SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gwl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CD2_A_FOLA207_0
(DIHYDROFOLATE
REDUCTASE)		 3gwl FAD-LINKED
SULFHYDRYL OXIDASE
(African
swine
fever
virus) 		5 / 12 ALA A 116
ILE A 135
PHE A 138
PHE A 152
LEU A 142
 None
None
None
None
FAD  A 334 (-4.6A)
 1.27A 4cd2A-3gwlA:
undetectable		 4cd2A-3gwlA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3gwl FAD-LINKED
SULFHYDRYL OXIDASE
(African
swine
fever
virus) 		4 / 8 SER A 165
ASP A 121
GLU A 166
GLN A 169
 None
 1.14A 4lnwA-3gwlA:
undetectable		 4lnwA-3gwlA:
18.15