SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gwy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3COT_A_STRA1501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 3gwy PUTATIVE CTP
PYROPHOSPHOHYDROLASE
(Bacteroides
fragilis) 		4 / 7 TYR A  95
GLU A  58
TRP A 116
TRP A 105
 None
 1.48A 3cotA-3gwyA:
undetectable		 3cotA-3gwyA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3gwy PUTATIVE CTP
PYROPHOSPHOHYDROLASE
(Bacteroides
fragilis) 		4 / 7 LEU A  87
LYS A  68
GLN A  48
LEU A  51
 None
 1.05A 4ib4A-3gwyA:
undetectable		 4ib4A-3gwyA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3gwy PUTATIVE CTP
PYROPHOSPHOHYDROLASE
(Bacteroides
fragilis) 		4 / 7 ILE A  55
LEU A  51
GLY A  39
GLY A  38
 None
 0.81A 5a06A-3gwyA:
undetectable		 5a06A-3gwyA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3gwy PUTATIVE CTP
PYROPHOSPHOHYDROLASE
(Bacteroides
fragilis) 		4 / 7 ILE A  55
LEU A  51
GLY A  39
GLY A  38
 None
 0.83A 5a06C-3gwyA:
undetectable		 5a06C-3gwyA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3gwy PUTATIVE CTP
PYROPHOSPHOHYDROLASE
(Bacteroides
fragilis) 		4 / 7 ILE A  55
LEU A  51
GLY A  39
GLY A  38
 None
 0.82A 5a06E-3gwyA:
undetectable		 5a06E-3gwyA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3gwy PUTATIVE CTP
PYROPHOSPHOHYDROLASE
(Bacteroides
fragilis) 		4 / 7 ILE A  55
LEU A  51
GLY A  39
GLY A  38
 None
 0.82A 5a06F-3gwyA:
undetectable		 5a06F-3gwyA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3gwy PUTATIVE CTP
PYROPHOSPHOHYDROLASE
(Bacteroides
fragilis) 		4 / 5 TYR A  61
ARG A  94
MET A  59
LEU A  97
 None
 1.38A 5x1fW-3gwyA:
undetectable		 5x1fW-3gwyA:
17.86