SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gx1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_G_AG2G7003_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3gx1 LIN1832 PROTEIN
(Listeria
innocua) 		4 / 6 LEU A 566
LEU A 646
GLY A 647
ILE A 653
 None
SO4  A 709 ( 4.2A)
None
None
 0.80A 1mt1G-3gx1A:
undetectable
1mt1J-3gx1A:
undetectable		 1mt1G-3gx1A:
21.54
1mt1J-3gx1A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_K_AG2K7002_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3gx1 LIN1832 PROTEIN
(Listeria
innocua) 		4 / 7 ILE A 653
LEU A 566
LEU A 646
GLY A 647
 None
None
SO4  A 709 ( 4.2A)
None
 0.83A 1mt1H-3gx1A:
undetectable
1mt1K-3gx1A:
undetectable		 1mt1H-3gx1A:
21.43
1mt1K-3gx1A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_F_AG2F7016_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3gx1 LIN1832 PROTEIN
(Listeria
innocua) 		4 / 8 LEU A 566
LEU A 646
GLY A 647
ILE A 653
 None
SO4  A 709 ( 4.2A)
None
None
 0.79A 1n13A-3gx1A:
undetectable
1n13F-3gx1A:
undetectable		 1n13A-3gx1A:
21.54
1n13F-3gx1A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_E_AG2E671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3gx1 LIN1832 PROTEIN
(Listeria
innocua) 		4 / 7 ILE A 653
LEU A 566
LEU A 646
GLY A 647
 None
None
SO4  A 709 ( 4.2A)
None
 0.85A 2qqcD-3gx1A:
undetectable
2qqcE-3gx1A:
undetectable		 2qqcD-3gx1A:
20.86
2qqcE-3gx1A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_K_AG2K671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3gx1 LIN1832 PROTEIN
(Listeria
innocua) 		4 / 8 ILE A 653
LEU A 566
LEU A 646
GLY A 647
 None
None
SO4  A 709 ( 4.2A)
None
 0.81A 2qqcH-3gx1A:
undetectable
2qqcK-3gx1A:
undetectable		 2qqcH-3gx1A:
20.86
2qqcK-3gx1A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_B_AG2B671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3gx1 LIN1832 PROTEIN
(Listeria
innocua) 		4 / 8 ILE A 653
LEU A 566
LEU A 646
GLY A 647
 None
None
SO4  A 709 ( 4.2A)
None
 0.74A 2qqdB-3gx1A:
undetectable
2qqdC-3gx1A:
undetectable		 2qqdB-3gx1A:
20.86
2qqdC-3gx1A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3gx1 LIN1832 PROTEIN
(Listeria
innocua) 		4 / 6 SER A 570
GLY A 649
ASP A 652
ARG A 648
 SO4  A 708 (-3.1A)
SO4  A 704 ( 3.9A)
None
SO4  A 702 ( 2.7A)
 0.94A 5cdnR-3gx1A:
undetectable
5cdnS-3gx1A:
3.7		 5cdnR-3gx1A:
15.15
5cdnS-3gx1A:
21.65