SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gxk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 3gxk GOOSE-TYPE LYSOZYME
1
(Gadus
morhua) 		4 / 8 ASP A   7
ILE A   8
THR A   9
PRO A  63
 None
 0.89A 1hmyA-3gxkA:
undetectable		 1hmyA-3gxkA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3gxk GOOSE-TYPE LYSOZYME
1
(Gadus
morhua) 		5 / 11 ASP A 118
GLY A 122
TYR A 151
ILE A 117
VAL A  55
 None
 1.47A 1tmxA-3gxkA:
undetectable		 1tmxA-3gxkA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3gxk GOOSE-TYPE LYSOZYME
1
(Gadus
morhua) 		5 / 12 ASP A 118
GLY A 122
TYR A 151
ILE A 117
VAL A  55
 None
 1.43A 1tmxB-3gxkA:
undetectable		 1tmxB-3gxkA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_A_GBNA502_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 3gxk GOOSE-TYPE LYSOZYME
1
(Gadus
morhua) 		4 / 8 GLY A 122
THR A 121
ALA A 120
TYR A 173
 None
 0.75A 2a1hA-3gxkA:
undetectable
2a1hB-3gxkA:
undetectable		 2a1hA-3gxkA:
20.33
2a1hB-3gxkA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_B_GBNB501_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 3gxk GOOSE-TYPE LYSOZYME
1
(Gadus
morhua) 		4 / 8 TYR A 173
GLY A 122
THR A 121
ALA A 120
 None
 0.76A 2a1hA-3gxkA:
undetectable
2a1hB-3gxkA:
undetectable		 2a1hA-3gxkA:
20.33
2a1hB-3gxkA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3gxk GOOSE-TYPE LYSOZYME
1
(Gadus
morhua) 		5 / 12 ILE A 131
GLN A 132
GLY A   6
ASP A   7
LEU A 124
 None
 1.11A 2zw9A-3gxkA:
undetectable		 2zw9A-3gxkA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3gxk GOOSE-TYPE LYSOZYME
1
(Gadus
morhua) 		4 / 5 ASN A  53
ALA A  56
PRO A  63
ALA A  67
 None
 1.28A 3twpD-3gxkA:
undetectable		 3twpD-3gxkA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3gxk GOOSE-TYPE LYSOZYME
1
(Gadus
morhua) 		3 / 3 ASP A 172
LYS A 171
ASP A 165
 None
 0.78A 4a7tA-3gxkA:
undetectable		 4a7tA-3gxkA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7G_A_ACTA514_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3gxk GOOSE-TYPE LYSOZYME
1
(Gadus
morhua) 		4 / 4 ALA A  64
VAL A  65
ASP A  62
LEU A 144
 None
 1.32A 4e7gA-3gxkA:
undetectable		 4e7gA-3gxkA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)		 3gxk GOOSE-TYPE LYSOZYME
1
(Gadus
morhua) 		4 / 6 ARG A 180
ALA A  33
ASP A 176
LEU A  26
 None
 1.11A 4ot2A-3gxkA:
undetectable		 4ot2A-3gxkA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)		 3gxk GOOSE-TYPE LYSOZYME
1
(Gadus
morhua) 		4 / 6 ARG A  75
ASP A  24
VAL A 177
ASP A 176
 None
 1.23A 4xqeA-3gxkA:
undetectable		 4xqeA-3gxkA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 3gxk GOOSE-TYPE LYSOZYME
1
(Gadus
morhua) 		4 / 6 ARG A  75
ASP A  24
VAL A 177
ASP A 176
 None
 1.24A 4xqeB-3gxkA:
undetectable		 4xqeB-3gxkA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 3gxk GOOSE-TYPE LYSOZYME
1
(Gadus
morhua) 		4 / 6 GLY A  15
THR A  13
SER A  34
VAL A  31
 None
 0.87A 5ewuA-3gxkA:
undetectable		 5ewuA-3gxkA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3gxk GOOSE-TYPE LYSOZYME
1
(Gadus
morhua) 		3 / 3 GLY A 156
ASP A 155
ASN A 126
 None
 0.41A 5jglA-3gxkA:
undetectable		 5jglA-3gxkA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3gxk GOOSE-TYPE LYSOZYME
1
(Gadus
morhua) 		3 / 3 VAL A 158
VAL A 164
GLN A 142
 None
 0.72A 5qglA-3gxkA:
undetectable		 5qglA-3gxkA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_1
(CARNOSINE
N-METHYLTRANSFERASE)		 3gxk GOOSE-TYPE LYSOZYME
1
(Gadus
morhua) 		4 / 5 ARG A 103
TYR A 104
GLU A  73
ASP A 176
 None
 1.48A 5yf0A-3gxkA:
undetectable		 5yf0A-3gxkA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_B_SAMB503_1
(CARNOSINE
N-METHYLTRANSFERASE)		 3gxk GOOSE-TYPE LYSOZYME
1
(Gadus
morhua) 		4 / 4 ARG A 103
TYR A 104
GLU A  73
ASP A 176
 None
 1.50A 5yf0B-3gxkA:
0.0		 5yf0B-3gxkA:
18.90