SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gxv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 3gxv REPLICATIVE DNA
HELICASE
(Helicobacter
pylori) 		4 / 8 PHE A  40
LEU A  53
ASP A  39
VAL A  98
 None
 0.70A 1iwiA-3gxvA:
undetectable		 1iwiA-3gxvA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 3gxv REPLICATIVE DNA
HELICASE
(Helicobacter
pylori) 		4 / 7 PHE A  40
LEU A  53
ASP A  39
VAL A  98
 None
 0.69A 4cp4A-3gxvA:
undetectable		 4cp4A-3gxvA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3gxv REPLICATIVE DNA
HELICASE
(Helicobacter
pylori) 		4 / 7 ARG A 108
ALA A 104
GLY A  46
GLU A  50
 None
 0.91A 5bs8A-3gxvA:
undetectable
5bs8C-3gxvA:
undetectable
5bs8D-3gxvA:
undetectable		 5bs8A-3gxvA:
13.50
5bs8C-3gxvA:
13.50
5bs8D-3gxvA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3gxv REPLICATIVE DNA
HELICASE
(Helicobacter
pylori) 		4 / 7 ALA A 104
GLY A  46
GLU A  50
ARG A 108
 None
 0.90A 5bs8A-3gxvA:
undetectable
5bs8B-3gxvA:
undetectable
5bs8C-3gxvA:
undetectable		 5bs8A-3gxvA:
13.50
5bs8B-3gxvA:
19.60
5bs8C-3gxvA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3gxv REPLICATIVE DNA
HELICASE
(Helicobacter
pylori) 		4 / 7 ALA A 104
GLY A  46
GLU A  50
ARG A 108
 None
 0.90A 5btdA-3gxvA:
undetectable
5btdB-3gxvA:
undetectable
5btdC-3gxvA:
undetectable		 5btdA-3gxvA:
13.50
5btdB-3gxvA:
19.60
5btdC-3gxvA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3gxv REPLICATIVE DNA
HELICASE
(Helicobacter
pylori) 		4 / 7 ARG A 108
ALA A 104
GLY A  46
GLU A  50
 None
 0.91A 5btdA-3gxvA:
undetectable
5btdC-3gxvA:
undetectable
5btdD-3gxvA:
undetectable		 5btdA-3gxvA:
13.50
5btdC-3gxvA:
13.50
5btdD-3gxvA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3gxv REPLICATIVE DNA
HELICASE
(Helicobacter
pylori) 		4 / 6 ALA A 104
GLY A  46
GLU A  50
ARG A 108
 None
 0.90A 5btgA-3gxvA:
undetectable
5btgB-3gxvA:
undetectable
5btgC-3gxvA:
undetectable		 5btgA-3gxvA:
13.50
5btgB-3gxvA:
19.60
5btgC-3gxvA:
13.50