SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gy9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOZ_A_CIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3gy9 GCN5-RELATED
N-ACETYLTRANSFERASE
(Exiguobacterium
sibiricum) 		5 / 12 ALA A  53
ILE A   5
LEU A 125
ILE A  78
MET A 101
 None
 1.02A 1xozA-3gy9A:
undetectable		 1xozA-3gy9A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 3gy9 GCN5-RELATED
N-ACETYLTRANSFERASE
(Exiguobacterium
sibiricum) 		5 / 12 GLY A  93
GLY A  91
VAL A  81
LEU A  97
ILE A 100
 COA  A 201 (-3.4A)
COA  A 201 (-3.2A)
COA  A 201 (-4.3A)
None
None
 1.00A 1zq9B-3gy9A:
undetectable		 1zq9B-3gy9A:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_A_VIAA901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3gy9 GCN5-RELATED
N-ACETYLTRANSFERASE
(Exiguobacterium
sibiricum) 		5 / 11 ALA A  53
ILE A   5
PHE A 121
LEU A 125
ILE A  78
 None
None
COA  A 201 (-3.8A)
None
None
 1.12A 2h42A-3gy9A:
undetectable		 2h42A-3gy9A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_B_VIAB902_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3gy9 GCN5-RELATED
N-ACETYLTRANSFERASE
(Exiguobacterium
sibiricum) 		5 / 12 ALA A  53
ILE A   5
LEU A 125
ILE A  78
MET A 101
 None
 1.06A 2h42B-3gy9A:
undetectable		 2h42B-3gy9A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 3gy9 GCN5-RELATED
N-ACETYLTRANSFERASE
(Exiguobacterium
sibiricum) 		4 / 8 PHE A 144
GLY A 126
PHE A 127
SER A 147
 None
 0.89A 3tzfB-3gy9A:
undetectable		 3tzfB-3gy9A:
22.10