SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gyk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FO4_A_SALA3005_1 (XANTHINE DEHYDROGENASE)	3gyk	27KDA OUTER MEMBRANE PROTEIN (Ruegeria pomeroyi)	5 / 9	LEU A 151 PHE A 139 VAL A 24 LEU A 5 ALA A 134	None	1.42A	1fo4A-3gykA: undetectable	1fo4A-3gykA: 8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CBR_A_A80A201_1 (PROTEIN (CRABP-I))	3gyk	27KDA OUTER MEMBRANE PROTEIN (Ruegeria pomeroyi)	5 / 12	PHE A 6 LEU A 53 VAL A 51 VAL A 165 ARG A 2	None	1.02A	2cbrA-3gykA: undetectable	2cbrA-3gykA: 20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QHF_A_ACTA508_0 (CHORISMATE SYNTHASE)	3gyk	27KDA OUTER MEMBRANE PROTEIN (Ruegeria pomeroyi)	4 / 5	LEU A 73 ARG A 70 ALA A 72 ILE A 127	None	1.09A	2qhfA-3gykA: undetectable	2qhfA-3gykA: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZGW_A_ADNA1301_1 (BIOTIN--[ACETYL-COA- CARBOXYLASE] LIGASE)	3gyk	27KDA OUTER MEMBRANE PROTEIN (Ruegeria pomeroyi)	4 / 7	ARG A 70 GLU A 57 ALA A 125 ASN A 10	None	1.11A	2zgwA-3gykA: undetectable	2zgwA-3gykA: 19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP6_B_SALB3007_1 (TRANSCRIPTIONAL REGULATOR TCAR)	3gyk	27KDA OUTER MEMBRANE PROTEIN (Ruegeria pomeroyi)	5 / 9	ALA A 132 LEU A 133 GLN A 129 SER A 4 ASN A 1	None	1.44A	3kp6B-3gykA: undetectable	3kp6B-3gykA: 18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VW7_A_VPXA2001_2 (PROTEINASE-ACTIVATED RECEPTOR 1, LYSOZYME)	3gyk	27KDA OUTER MEMBRANE PROTEIN (Ruegeria pomeroyi)	4 / 4	PRO A 17 LEU A 53 HIS A 85 LEU A 88	None	1.16A	3vw7A-3gykA: undetectable	3vw7A-3gykA: 15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BP4_A_SAMA505_1 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC)	3gyk	27KDA OUTER MEMBRANE PROTEIN (Ruegeria pomeroyi)	3 / 3	ILE A 103 ASN A 30 CYH A 34	None	0.89A	6bp4A-3gykA: undetectable	6bp4A-3gykA: 22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6QGB_A_BEZA701_0 (MONO(2-HYDROXYETHYL) TEREPHTHALATE HYDROLASE)	3gyk	27KDA OUTER MEMBRANE PROTEIN (Ruegeria pomeroyi)	5 / 11	GLY A 99 LEU A 88 ALA A 87 ALA A 104 PHE A 84	None	1.37A	6qgbA-3gykA: undetectable	6qgbA-3gykA: 15.91

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FO4_A_SALA3005_1","XANTHINE DEHYDROGENASE","3gyk","27KDA OUTER MEMBRANE PROTEIN","Ruegeria pomeroyi",5,"LEU A 151;PHE A 139;VAL A  24;LEU A   5;ALA A 134","None","1.42A","1fo4A-3gykA:undetectable","1fo4A-3gykA:8.48"],["2CBR_A_A80A201_1","PROTEIN (CRABP-I)","3gyk","27KDA OUTER MEMBRANE PROTEIN","Ruegeria pomeroyi",5,"PHE A   6;LEU A  53;VAL A  51;VAL A 165;ARG A   2","None","1.02A","2cbrA-3gykA:undetectable","2cbrA-3gykA:20.99"],["2QHF_A_ACTA508_0","CHORISMATE SYNTHASE","3gyk","27KDA OUTER MEMBRANE PROTEIN","Ruegeria pomeroyi",4,"LEU A  73;ARG A  70;ALA A  72;ILE A 127","None","1.09A","2qhfA-3gykA:undetectable","2qhfA-3gykA:21.13"],["2ZGW_A_ADNA1301_1","BIOTIN--[ACETYL-COA-CARBOXYLASE] LIGASE","3gyk","27KDA OUTER MEMBRANE PROTEIN","Ruegeria pomeroyi",4,"ARG A  70;GLU A  57;ALA A 125;ASN A  10","None","1.11A","2zgwA-3gykA:undetectable","2zgwA-3gykA:19.74"],["3KP6_B_SALB3007_1","TRANSCRIPTIONAL REGULATOR TCAR","3gyk","27KDA OUTER MEMBRANE PROTEIN","Ruegeria pomeroyi",5,"ALA A 132;LEU A 133;GLN A 129;SER A   4;ASN A   1","None","1.44A","3kp6B-3gykA:undetectable","3kp6B-3gykA:18.89"],["3VW7_A_VPXA2001_2","PROTEINASE-ACTIVATED RECEPTOR 1, LYSOZYME","3gyk","27KDA OUTER MEMBRANE PROTEIN","Ruegeria pomeroyi",4,"PRO A  17;LEU A  53;HIS A  85;LEU A  88","None","1.16A","3vw7A-3gykA:undetectable","3vw7A-3gykA:15.50"],["6BP4_A_SAMA505_1","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC","3gyk","27KDA OUTER MEMBRANE PROTEIN","Ruegeria pomeroyi",3,"ILE A 103;ASN A  30;CYH A  34","None","0.89A","6bp4A-3gykA:undetectable","6bp4A-3gykA:22.15"],["6QGB_A_BEZA701_0","MONO(2-HYDROXYETHYL) TEREPHTHALATE HYDROLASE","3gyk","27KDA OUTER MEMBRANE PROTEIN","Ruegeria pomeroyi",5,"GLY A  99;LEU A  88;ALA A  87;ALA A 104;PHE A  84","None","1.37A","6qgbA-3gykA:undetectable","6qgbA-3gykA:15.91"]]