SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gyq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FM6_X_BRLX504_1 (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	5 / 12	ILE A 146 GLY A 144 SER A 137 LEU A 195 LEU A 257	None None None SAM A 270 (-4.1A) None	1.35A	1fm6X-3gyqA: undetectable	1fm6X-3gyqA: 21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SA1_B_PODB700_1 (TUBULIN ALPHA CHAIN TUBULIN BETA CHAIN)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	5 / 12	VAL A 203 LEU A 121 LEU A 253 VAL A 118 ALA A 214	None	1.17A	1sa1A-3gyqA: undetectable 1sa1B-3gyqA: undetectable	1sa1A-3gyqA: 20.68 1sa1B-3gyqA: 21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V2X_A_SAMA400_0 (TRNA (GM18) METHYLTRANSFERASE)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	6 / 12	GLY A 223 GLY A 222 ILE A 238 MET A 240 SER A 246 LEU A 247	None None SAM A 270 (-3.5A) SAM A 270 (-3.5A) SAM A 270 (-2.8A) SAM A 270 (-4.4A)	1.26A	1v2xA-3gyqA: 17.5	1v2xA-3gyqA: 23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V2X_A_SAMA400_0 (TRNA (GM18) METHYLTRANSFERASE)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	5 / 12	PHE A 217 GLY A 218 GLY A 223 ILE A 238 LEU A 247	None SAM A 270 (-2.9A) None SAM A 270 (-3.5A) SAM A 270 (-4.4A)	0.67A	1v2xA-3gyqA: 17.5	1v2xA-3gyqA: 23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V2X_A_SAMA400_0 (TRNA (GM18) METHYLTRANSFERASE)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	7 / 12	PHE A 217 GLY A 218 ILE A 238 MET A 240 SER A 246 LEU A 247 VAL A 249	None SAM A 270 (-2.9A) SAM A 270 (-3.5A) SAM A 270 (-3.5A) SAM A 270 (-2.8A) SAM A 270 (-4.4A) SAM A 270 ( 4.2A)	0.77A	1v2xA-3gyqA: 17.5	1v2xA-3gyqA: 23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1X7P_A_SAMA301_0 (RRNA METHYLTRANSFERASE)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	6 / 11	GLY A 218 GLY A 223 ILE A 238 MET A 240 SER A 246 LEU A 247	SAM A 270 (-2.9A) None SAM A 270 (-3.5A) SAM A 270 (-3.5A) SAM A 270 (-2.8A) SAM A 270 (-4.4A)	0.91A	1x7pA-3gyqA: 20.9 1x7pB-3gyqA: 22.8	1x7pA-3gyqA: 27.99 1x7pB-3gyqA: 27.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1X7P_B_SAMB302_0 (RRNA METHYLTRANSFERASE)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	5 / 10	GLY A 218 GLY A 223 ILE A 238 MET A 240 LEU A 247	SAM A 270 (-2.9A) None SAM A 270 (-3.5A) SAM A 270 (-3.5A) SAM A 270 (-4.4A)	0.78A	1x7pA-3gyqA: 20.9 1x7pB-3gyqA: 22.8	1x7pA-3gyqA: 27.99 1x7pB-3gyqA: 27.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V95_A_HCYA1375_1 (CORTICOSTEROID-BINDI NG GLOBULIN)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	5 / 12	ALA A 14 PRO A 13 PHE A 97 ILE A 19 ASP A 20	None	1.29A	2v95A-3gyqA: undetectable	2v95A-3gyqA: 23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AXZ_A_ADNA401_1 (TRNA (GUANINE-N(1)-)-METH YLTRANSFERASE)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	5 / 12	LEU A 195 GLY A 218 GLY A 223 SER A 237 ILE A 238	SAM A 270 (-4.1A) SAM A 270 (-2.9A) None SAM A 270 (-4.3A) SAM A 270 (-3.5A)	0.69A	3axzA-3gyqA: 7.7	3axzA-3gyqA: 21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DCM_X_SAMX5452_0 (UNCHARACTERIZED PROTEIN TM_1570)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	6 / 11	ALA A 197 GLY A 218 GLY A 223 ILE A 238 LEU A 247 VAL A 249	SAM A 270 (-3.8A) SAM A 270 (-2.9A) None SAM A 270 (-3.5A) SAM A 270 (-4.4A) SAM A 270 ( 4.2A)	0.69A	3dcmX-3gyqA: 14.5	3dcmX-3gyqA: 23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EM0_B_CHDB151_0 (ILEAL BILE ACID-BINDING PROTEIN)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	5 / 12	ILE A 111 ILE A 146 VAL A 148 LEU A 253 LEU A 171	None	1.05A	3em0B-3gyqA: undetectable	3em0B-3gyqA: 19.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GYQ_A_SAMA270_0 (RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	10 / 12	LEU A 195 LYS A 196 ALA A 197 GLY A 218 LYS A 221 ILE A 238 MET A 240 SER A 246 LEU A 247 SER A 252	SAM A 270 (-4.1A) SAM A 270 (-3.3A) SAM A 270 (-3.8A) SAM A 270 (-2.9A) None SAM A 270 (-3.5A) SAM A 270 (-3.5A) SAM A 270 (-2.8A) SAM A 270 (-4.4A) SAM A 270 (-3.1A)	0.03A	3gyqA-3gyqA: 44.5 3gyqB-3gyqA: 39.3	3gyqA-3gyqA: 100.00 3gyqB-3gyqA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GYQ_A_SAMA270_0 (RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	7 / 12	LYS A 196 ALA A 197 GLY A 223 ILE A 238 MET A 240 SER A 246 LEU A 247	SAM A 270 (-3.3A) SAM A 270 (-3.8A) None SAM A 270 (-3.5A) SAM A 270 (-3.5A) SAM A 270 (-2.8A) SAM A 270 (-4.4A)	1.22A	3gyqA-3gyqA: 44.5 3gyqB-3gyqA: 39.3	3gyqA-3gyqA: 100.00 3gyqB-3gyqA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GYQ_B_SAMB270_0 (RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	8 / 11	GLY A 218 LYS A 221 ILE A 238 MET A 240 SER A 246 LEU A 247 VAL A 249 SER A 252	SAM A 270 (-2.9A) None SAM A 270 (-3.5A) SAM A 270 (-3.5A) SAM A 270 (-2.8A) SAM A 270 (-4.4A) SAM A 270 ( 4.2A) SAM A 270 (-3.1A)	0.86A	3gyqB-3gyqA: 39.3	3gyqB-3gyqA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GYQ_B_SAMB270_0 (RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	10 / 11	LEU A 195 LYS A 196 ALA A 197 GLY A 218 LYS A 221 ILE A 238 MET A 240 LEU A 247 VAL A 249 SER A 252	SAM A 270 (-4.1A) SAM A 270 (-3.3A) SAM A 270 (-3.8A) SAM A 270 (-2.9A) None SAM A 270 (-3.5A) SAM A 270 (-3.5A) SAM A 270 (-4.4A) SAM A 270 ( 4.2A) SAM A 270 (-3.1A)	0.43A	3gyqB-3gyqA: 39.3	3gyqB-3gyqA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GYQ_B_SAMB270_0 (RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	6 / 11	LYS A 196 ALA A 197 GLY A 223 ILE A 238 MET A 240 LEU A 247	SAM A 270 (-3.3A) SAM A 270 (-3.8A) None SAM A 270 (-3.5A) SAM A 270 (-3.5A) SAM A 270 (-4.4A)	1.38A	3gyqB-3gyqA: 39.3	3gyqB-3gyqA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3NK7_A_SAMA770_0 (23S RRNA METHYLTRANSFERASE)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	6 / 12	ASN A 129 GLY A 218 MET A 240 SER A 246 ASN A 248 VAL A 249	None SAM A 270 (-2.9A) SAM A 270 (-3.5A) SAM A 270 (-2.8A) SAM A 270 ( 4.9A) SAM A 270 ( 4.2A)	0.92A	3nk7A-3gyqA: 30.7	3nk7A-3gyqA: 73.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3NK7_A_SAMA770_0 (23S RRNA METHYLTRANSFERASE)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	9 / 12	ASN A 129 LEU A 195 GLY A 218 GLY A 223 ILE A 238 MET A 240 ASN A 248 VAL A 249 SER A 252	None SAM A 270 (-4.1A) SAM A 270 (-2.9A) None SAM A 270 (-3.5A) SAM A 270 (-3.5A) SAM A 270 ( 4.9A) SAM A 270 ( 4.2A) SAM A 270 (-3.1A)	0.59A	3nk7A-3gyqA: 30.7	3nk7A-3gyqA: 73.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3NK7_B_SAMB770_0 (23S RRNA METHYLTRANSFERASE)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	8 / 12	ASN A 129 GLY A 218 GLY A 223 ILE A 238 MET A 240 SER A 246 LEU A 247 VAL A 249	None SAM A 270 (-2.9A) None SAM A 270 (-3.5A) SAM A 270 (-3.5A) SAM A 270 (-2.8A) SAM A 270 (-4.4A) SAM A 270 ( 4.2A)	0.92A	3nk7B-3gyqA: 30.7	3nk7B-3gyqA: 73.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3NK7_B_SAMB770_0 (23S RRNA METHYLTRANSFERASE)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	10 / 12	ASN A 129 LEU A 195 PHE A 217 GLY A 218 GLY A 223 ILE A 238 MET A 240 LEU A 247 VAL A 249 SER A 252	None SAM A 270 (-4.1A) None SAM A 270 (-2.9A) None SAM A 270 (-3.5A) SAM A 270 (-3.5A) SAM A 270 (-4.4A) SAM A 270 ( 4.2A) SAM A 270 (-3.1A)	0.61A	3nk7B-3gyqA: 30.7	3nk7B-3gyqA: 73.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3NK7_B_SAMB770_0 (23S RRNA METHYLTRANSFERASE)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	6 / 12	LEU A 195 PHE A 217 GLU A 220 ILE A 238 MET A 240 SER A 252	SAM A 270 (-4.1A) None None SAM A 270 (-3.5A) SAM A 270 (-3.5A) SAM A 270 (-3.1A)	1.06A	3nk7B-3gyqA: 30.7	3nk7B-3gyqA: 73.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TQ8_A_TOPA2001_1 (DIHYDROFOLATE REDUCTASE)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	5 / 9	ILE A 145 ALA A 142 SER A 188 ILE A 185 ILE A 146	None	1.16A	3tq8A-3gyqA: 2.7	3tq8A-3gyqA: 21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X3M_A_ADNA301_1 (RNA 2'-O RIBOSE METHYLTRANSFERASE)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	5 / 9	GLY A 218 ILE A 238 MET A 240 SER A 246 VAL A 249	SAM A 270 (-2.9A) SAM A 270 (-3.5A) SAM A 270 (-3.5A) SAM A 270 (-2.8A) SAM A 270 ( 4.2A)	0.91A	4x3mA-3gyqA: 22.8	4x3mA-3gyqA: 29.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X3M_B_ADNB301_1 (RNA 2'-O RIBOSE METHYLTRANSFERASE)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	5 / 9	GLY A 218 ILE A 238 MET A 240 LEU A 247 VAL A 249	SAM A 270 (-2.9A) SAM A 270 (-3.5A) SAM A 270 (-3.5A) SAM A 270 (-4.4A) SAM A 270 ( 4.2A)	0.62A	4x3mB-3gyqA: 22.9	4x3mB-3gyqA: 29.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X3M_B_ADNB301_1 (RNA 2'-O RIBOSE METHYLTRANSFERASE)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	5 / 9	ILE A 238 MET A 240 SER A 246 LEU A 247 VAL A 249	SAM A 270 (-3.5A) SAM A 270 (-3.5A) SAM A 270 (-2.8A) SAM A 270 (-4.4A) SAM A 270 ( 4.2A)	0.78A	4x3mB-3gyqA: 22.9	4x3mB-3gyqA: 29.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YSH_B_GLYB401_0 (GLYCINE OXIDASE)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	4 / 6	PHE A 97 LYS A 95 GLY A 55 TYR A 54	None	1.09A	4yshB-3gyqA: undetectable	4yshB-3gyqA: 23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JVZ_B_FLPB601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	5 / 12	VAL A 173 LEU A 171 LEU A 147 GLY A 166 LEU A 160	None	1.14A	5jvzB-3gyqA: undetectable	5jvzB-3gyqA: 19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L0Z_A_SAMA304_0 (PROBABLE RNA METHYLTRANSFERASE, TRMH FAMILY)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	5 / 12	GLY A 218 GLY A 223 ILE A 238 SER A 246 LEU A 247	SAM A 270 (-2.9A) None SAM A 270 (-3.5A) SAM A 270 (-2.8A) SAM A 270 (-4.4A)	0.85A	5l0zA-3gyqA: 22.9	5l0zA-3gyqA: 27.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L0Z_B_SAMB304_0 (PROBABLE RNA METHYLTRANSFERASE, TRMH FAMILY)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	5 / 10	GLY A 218 GLY A 223 ILE A 238 SER A 246 LEU A 247	SAM A 270 (-2.9A) None SAM A 270 (-3.5A) SAM A 270 (-2.8A) SAM A 270 (-4.4A)	0.77A	5l0zB-3gyqA: 23.1	5l0zB-3gyqA: 27.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VOP_B_C2FB3001_0 (5-METHYLTETRAHYDROFO LATE HOMOCYSTEINE S-METHYLTRANSFERASE)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	5 / 12	ASN A 264 GLY A 141 VAL A 203 LEU A 195 GLY A 254	None None None SAM A 270 (-4.1A) None	1.06A	5vopB-3gyqA: undetectable	5vopB-3gyqA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZHM_B_SAMB301_1 (TRNA (GUANINE-N(1)-)-METH YLTRANSFERASE)	3gyq	RRNA (ADENOSINE-2'-O-)-ME THYLTRANSFERASE (Streptomyces cyaneus)	5 / 12	LEU A 195 GLY A 218 GLY A 223 SER A 237 ILE A 238	SAM A 270 (-4.1A) SAM A 270 (-2.9A) None SAM A 270 (-4.3A) SAM A 270 (-3.5A)	0.86A	5zhmB-3gyqA: 7.7	5zhmB-3gyqA: 24.43

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FM6_X_BRLX504_1","PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",5,"ILE A 146;GLY A 144;SER A 137;LEU A 195;LEU A 257","None;None;None;SAM A 270 (-4.1A);None","1.35A","1fm6X-3gyqA:undetectable","1fm6X-3gyqA:21.58"],["1SA1_B_PODB700_1","TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",5,"VAL A 203;LEU A 121;LEU A 253;VAL A 118;ALA A 214","None","1.17A","1sa1A-3gyqA:undetectable;1sa1B-3gyqA:undetectable","1sa1A-3gyqA:20.68;1sa1B-3gyqA:21.75"],["1V2X_A_SAMA400_0","TRNA (GM18) METHYLTRANSFERASE","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",6,"GLY A 223;GLY A 222;ILE A 238;MET A 240;SER A 246;LEU A 247","None;None;SAM A 270 (-3.5A);SAM A 270 (-3.5A);SAM A 270 (-2.8A);SAM A 270 (-4.4A)","1.26A","1v2xA-3gyqA:17.5","1v2xA-3gyqA:23.83"],["1V2X_A_SAMA400_0","TRNA (GM18) METHYLTRANSFERASE","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",5,"PHE A 217;GLY A 218;GLY A 223;ILE A 238;LEU A 247","None;SAM A 270 (-2.9A);None;SAM A 270 (-3.5A);SAM A 270 (-4.4A)","0.67A","1v2xA-3gyqA:17.5","1v2xA-3gyqA:23.83"],["1V2X_A_SAMA400_0","TRNA (GM18) METHYLTRANSFERASE","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",7,"PHE A 217;GLY A 218;ILE A 238;MET A 240;SER A 246;LEU A 247;VAL A 249","None;SAM A 270 (-2.9A);SAM A 270 (-3.5A);SAM A 270 (-3.5A);SAM A 270 (-2.8A);SAM A 270 (-4.4A);SAM A 270 ( 4.2A)","0.77A","1v2xA-3gyqA:17.5","1v2xA-3gyqA:23.83"],["1X7P_A_SAMA301_0","RRNA METHYLTRANSFERASE","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",6,"GLY A 218;GLY A 223;ILE A 238;MET A 240;SER A 246;LEU A 247","SAM A 270 (-2.9A);None;SAM A 270 (-3.5A);SAM A 270 (-3.5A);SAM A 270 (-2.8A);SAM A 270 (-4.4A)","0.91A","1x7pA-3gyqA:20.9;1x7pB-3gyqA:22.8","1x7pA-3gyqA:27.99;1x7pB-3gyqA:27.99"],["1X7P_B_SAMB302_0","RRNA METHYLTRANSFERASE","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",5,"GLY A 218;GLY A 223;ILE A 238;MET A 240;LEU A 247","SAM A 270 (-2.9A);None;SAM A 270 (-3.5A);SAM A 270 (-3.5A);SAM A 270 (-4.4A)","0.78A","1x7pA-3gyqA:20.9;1x7pB-3gyqA:22.8","1x7pA-3gyqA:27.99;1x7pB-3gyqA:27.99"],["2V95_A_HCYA1375_1","CORTICOSTEROID-BINDING GLOBULIN","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",5,"ALA A  14;PRO A  13;PHE A  97;ILE A  19;ASP A  20","None","1.29A","2v95A-3gyqA:undetectable","2v95A-3gyqA:23.33"],["3AXZ_A_ADNA401_1","TRNA (GUANINE-N(1)-)-METHYLTRANSFERASE","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",5,"LEU A 195;GLY A 218;GLY A 223;SER A 237;ILE A 238","SAM A 270 (-4.1A);SAM A 270 (-2.9A);None;SAM A 270 (-4.3A);SAM A 270 (-3.5A)","0.69A","3axzA-3gyqA:7.7","3axzA-3gyqA:21.36"],["3DCM_X_SAMX5452_0","UNCHARACTERIZED PROTEIN TM_1570","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",6,"ALA A 197;GLY A 218;GLY A 223;ILE A 238;LEU A 247;VAL A 249","SAM A 270 (-3.8A);SAM A 270 (-2.9A);None;SAM A 270 (-3.5A);SAM A 270 (-4.4A);SAM A 270 ( 4.2A)","0.69A","3dcmX-3gyqA:14.5","3dcmX-3gyqA:23.27"],["3EM0_B_CHDB151_0","ILEAL BILE ACID-BINDING PROTEIN","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",5,"ILE A 111;ILE A 146;VAL A 148;LEU A 253;LEU A 171","None","1.05A","3em0B-3gyqA:undetectable","3em0B-3gyqA:19.33"],["3GYQ_A_SAMA270_0","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",10,"LEU A 195;LYS A 196;ALA A 197;GLY A 218;LYS A 221;ILE A 238;MET A 240;SER A 246;LEU A 247;SER A 252","SAM A 270 (-4.1A);SAM A 270 (-3.3A);SAM A 270 (-3.8A);SAM A 270 (-2.9A);None;SAM A 270 (-3.5A);SAM A 270 (-3.5A);SAM A 270 (-2.8A);SAM A 270 (-4.4A);SAM A 270 (-3.1A)","0.03A","3gyqA-3gyqA:44.5;3gyqB-3gyqA:39.3","3gyqA-3gyqA:100.00;3gyqB-3gyqA:100.00"],["3GYQ_A_SAMA270_0","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",7,"LYS A 196;ALA A 197;GLY A 223;ILE A 238;MET A 240;SER A 246;LEU A 247","SAM A 270 (-3.3A);SAM A 270 (-3.8A);None;SAM A 270 (-3.5A);SAM A 270 (-3.5A);SAM A 270 (-2.8A);SAM A 270 (-4.4A)","1.22A","3gyqA-3gyqA:44.5;3gyqB-3gyqA:39.3","3gyqA-3gyqA:100.00;3gyqB-3gyqA:100.00"],["3GYQ_B_SAMB270_0","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",8,"GLY A 218;LYS A 221;ILE A 238;MET A 240;SER A 246;LEU A 247;VAL A 249;SER A 252","SAM A 270 (-2.9A);None;SAM A 270 (-3.5A);SAM A 270 (-3.5A);SAM A 270 (-2.8A);SAM A 270 (-4.4A);SAM A 270 ( 4.2A);SAM A 270 (-3.1A)","0.86A","3gyqB-3gyqA:39.3","3gyqB-3gyqA:100.00"],["3GYQ_B_SAMB270_0","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",10,"LEU A 195;LYS A 196;ALA A 197;GLY A 218;LYS A 221;ILE A 238;MET A 240;LEU A 247;VAL A 249;SER A 252","SAM A 270 (-4.1A);SAM A 270 (-3.3A);SAM A 270 (-3.8A);SAM A 270 (-2.9A);None;SAM A 270 (-3.5A);SAM A 270 (-3.5A);SAM A 270 (-4.4A);SAM A 270 ( 4.2A);SAM A 270 (-3.1A)","0.43A","3gyqB-3gyqA:39.3","3gyqB-3gyqA:100.00"],["3GYQ_B_SAMB270_0","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",6,"LYS A 196;ALA A 197;GLY A 223;ILE A 238;MET A 240;LEU A 247","SAM A 270 (-3.3A);SAM A 270 (-3.8A);None;SAM A 270 (-3.5A);SAM A 270 (-3.5A);SAM A 270 (-4.4A)","1.38A","3gyqB-3gyqA:39.3","3gyqB-3gyqA:100.00"],["3NK7_A_SAMA770_0","23S RRNA METHYLTRANSFERASE","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",6,"ASN A 129;GLY A 218;MET A 240;SER A 246;ASN A 248;VAL A 249","None;SAM A 270 (-2.9A);SAM A 270 (-3.5A);SAM A 270 (-2.8A);SAM A 270 ( 4.9A);SAM A 270 ( 4.2A)","0.92A","3nk7A-3gyqA:30.7","3nk7A-3gyqA:73.53"],["3NK7_A_SAMA770_0","23S RRNA METHYLTRANSFERASE","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",9,"ASN A 129;LEU A 195;GLY A 218;GLY A 223;ILE A 238;MET A 240;ASN A 248;VAL A 249;SER A 252","None;SAM A 270 (-4.1A);SAM A 270 (-2.9A);None;SAM A 270 (-3.5A);SAM A 270 (-3.5A);SAM A 270 ( 4.9A);SAM A 270 ( 4.2A);SAM A 270 (-3.1A)","0.59A","3nk7A-3gyqA:30.7","3nk7A-3gyqA:73.53"],["3NK7_B_SAMB770_0","23S RRNA METHYLTRANSFERASE","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",8,"ASN A 129;GLY A 218;GLY A 223;ILE A 238;MET A 240;SER A 246;LEU A 247;VAL A 249","None;SAM A 270 (-2.9A);None;SAM A 270 (-3.5A);SAM A 270 (-3.5A);SAM A 270 (-2.8A);SAM A 270 (-4.4A);SAM A 270 ( 4.2A)","0.92A","3nk7B-3gyqA:30.7","3nk7B-3gyqA:73.53"],["3NK7_B_SAMB770_0","23S RRNA METHYLTRANSFERASE","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",10,"ASN A 129;LEU A 195;PHE A 217;GLY A 218;GLY A 223;ILE A 238;MET A 240;LEU A 247;VAL A 249;SER A 252","None;SAM A 270 (-4.1A);None;SAM A 270 (-2.9A);None;SAM A 270 (-3.5A);SAM A 270 (-3.5A);SAM A 270 (-4.4A);SAM A 270 ( 4.2A);SAM A 270 (-3.1A)","0.61A","3nk7B-3gyqA:30.7","3nk7B-3gyqA:73.53"],["3NK7_B_SAMB770_0","23S RRNA METHYLTRANSFERASE","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",6,"LEU A 195;PHE A 217;GLU A 220;ILE A 238;MET A 240;SER A 252","SAM A 270 (-4.1A);None;None;SAM A 270 (-3.5A);SAM A 270 (-3.5A);SAM A 270 (-3.1A)","1.06A","3nk7B-3gyqA:30.7","3nk7B-3gyqA:73.53"],["3TQ8_A_TOPA2001_1","DIHYDROFOLATE REDUCTASE","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",5,"ILE A 145;ALA A 142;SER A 188;ILE A 185;ILE A 146","None","1.16A","3tq8A-3gyqA:2.7","3tq8A-3gyqA:21.03"],["4X3M_A_ADNA301_1","RNA 2'-O RIBOSE METHYLTRANSFERASE","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",5,"GLY A 218;ILE A 238;MET A 240;SER A 246;VAL A 249","SAM A 270 (-2.9A);SAM A 270 (-3.5A);SAM A 270 (-3.5A);SAM A 270 (-2.8A);SAM A 270 ( 4.2A)","0.91A","4x3mA-3gyqA:22.8","4x3mA-3gyqA:29.23"],["4X3M_B_ADNB301_1","RNA 2'-O RIBOSE METHYLTRANSFERASE","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",5,"GLY A 218;ILE A 238;MET A 240;LEU A 247;VAL A 249","SAM A 270 (-2.9A);SAM A 270 (-3.5A);SAM A 270 (-3.5A);SAM A 270 (-4.4A);SAM A 270 ( 4.2A)","0.62A","4x3mB-3gyqA:22.9","4x3mB-3gyqA:29.23"],["4X3M_B_ADNB301_1","RNA 2'-O RIBOSE METHYLTRANSFERASE","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",5,"ILE A 238;MET A 240;SER A 246;LEU A 247;VAL A 249","SAM A 270 (-3.5A);SAM A 270 (-3.5A);SAM A 270 (-2.8A);SAM A 270 (-4.4A);SAM A 270 ( 4.2A)","0.78A","4x3mB-3gyqA:22.9","4x3mB-3gyqA:29.23"],["4YSH_B_GLYB401_0","GLYCINE OXIDASE","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",4,"PHE A  97;LYS A  95;GLY A  55;TYR A  54","None","1.09A","4yshB-3gyqA:undetectable","4yshB-3gyqA:23.22"],["5JVZ_B_FLPB601_1","PROSTAGLANDIN G\/H SYNTHASE 2","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",5,"VAL A 173;LEU A 171;LEU A 147;GLY A 166;LEU A 160","None","1.14A","5jvzB-3gyqA:undetectable","5jvzB-3gyqA:19.07"],["5L0Z_A_SAMA304_0","PROBABLE RNA METHYLTRANSFERASE, TRMH FAMILY","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",5,"GLY A 218;GLY A 223;ILE A 238;SER A 246;LEU A 247","SAM A 270 (-2.9A);None;SAM A 270 (-3.5A);SAM A 270 (-2.8A);SAM A 270 (-4.4A)","0.85A","5l0zA-3gyqA:22.9","5l0zA-3gyqA:27.36"],["5L0Z_B_SAMB304_0","PROBABLE RNA METHYLTRANSFERASE, TRMH FAMILY","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",5,"GLY A 218;GLY A 223;ILE A 238;SER A 246;LEU A 247","SAM A 270 (-2.9A);None;SAM A 270 (-3.5A);SAM A 270 (-2.8A);SAM A 270 (-4.4A)","0.77A","5l0zB-3gyqA:23.1","5l0zB-3gyqA:27.36"],["5VOP_B_C2FB3001_0","5-METHYLTETRAHYDROFOLATE HOMOCYSTEINE S-METHYLTRANSFERASE","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",5,"ASN A 264;GLY A 141;VAL A 203;LEU A 195;GLY A 254","None;None;None;SAM A 270 (-4.1A);None","1.06A","5vopB-3gyqA:undetectable","5vopB-3gyqA:21.43"],["5ZHM_B_SAMB301_1","TRNA (GUANINE-N(1)-)-METHYLTRANSFERASE","3gyq","RRNA (ADENOSINE-2'-O-)-METHYLTRANSFERASE","Streptomyces cyaneus",5,"LEU A 195;GLY A 218;GLY A 223;SER A 237;ILE A 238","SAM A 270 (-4.1A);SAM A 270 (-2.9A);None;SAM A 270 (-4.3A);SAM A 270 (-3.5A)","0.86A","5zhmB-3gyqA:7.7","5zhmB-3gyqA:24.43"]]