SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gyr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E3V_B_DXCB801_0
(STEROID
DELTA-ISOMERASE)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 11 ASP A 202
TYR A  88
GLY A 215
LEU A 154
ALA A 204
 None
 1.41A 1e3vB-3gyrA:
0.0		 1e3vB-3gyrA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 6 HIS A 201
HIS A 203
HIS A 602
HIS A 527
HIS A 163
 C2O  A1002 (-3.7A)
C2O  A1002 (-3.4A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
 1.20A 1fweC-3gyrA:
undetectable		 1fweC-3gyrA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 8 THR A 450
GLY A 452
PHE A 546
ARG A 496
 None
 0.81A 1h4oB-3gyrA:
undetectable		 1h4oB-3gyrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 8 THR A 450
GLY A 452
PHE A 546
ARG A 496
 None
 0.82A 1h4oG-3gyrA:
undetectable		 1h4oG-3gyrA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 6 ILE A 316
ASN A 310
SER A 312
THR A 287
 None
 0.94A 1h7xB-3gyrA:
undetectable		 1h7xB-3gyrA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 8 THR A 450
GLY A 452
PHE A 546
ARG A 496
 None
 0.81A 1oc3A-3gyrA:
undetectable		 1oc3A-3gyrA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 524
CYH A 603
HIS A 608
MET A 613
 CU  A1000 (-3.0A)
CU  A1000 (-2.2A)
CU  A1000 (-3.6A)
CU  A1000 (-3.5A)
 0.71A 1oe1A-3gyrA:
21.1		 1oe1A-3gyrA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 524
CYH A 603
HIS A 608
MET A 613
 CU  A1000 (-3.0A)
CU  A1000 (-2.2A)
CU  A1000 (-3.6A)
CU  A1000 (-3.5A)
 0.69A 1oe2A-3gyrA:
17.4		 1oe2A-3gyrA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 524
CYH A 603
HIS A 608
MET A 613
 CU  A1000 (-3.0A)
CU  A1000 (-2.2A)
CU  A1000 (-3.6A)
CU  A1000 (-3.5A)
 0.73A 1oe3A-3gyrA:
21.2		 1oe3A-3gyrA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK2_A_ACAA91_1
(TISSUE-TYPE
PLASMINOGEN
ACTIVATOR)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 8 ASP A 576
ASP A 339
HIS A 201
LEU A 606
 None
None
C2O  A1002 (-3.7A)
None
 1.09A 1pk2A-3gyrA:
undetectable		 1pk2A-3gyrA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK2_A_ACAA91_1
(TISSUE-TYPE
PLASMINOGEN
ACTIVATOR)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 8 VAL A 332
ASP A 417
TRP A 303
HIS A 334
 None
 1.26A 1pk2A-3gyrA:
undetectable		 1pk2A-3gyrA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 8 PHE A 283
ASN A 137
SER A 279
ALA A 135
 None
 0.89A 1rqpC-3gyrA:
undetectable		 1rqpC-3gyrA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 8 PHE A 283
ASN A 137
SER A 279
ALA A 135
 None
 0.89A 1rqpA-3gyrA:
undetectable		 1rqpA-3gyrA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 12 LEU A 241
LEU A 308
LEU A 321
GLU A 407
VAL A 289
 None
 1.11A 1sn5B-3gyrA:
undetectable
1sn5D-3gyrA:
undetectable		 1sn5B-3gyrA:
14.26
1sn5D-3gyrA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 12 LEU A 321
GLU A 407
VAL A 289
LEU A 241
LEU A 308
 None
 1.07A 1sn5B-3gyrA:
undetectable
1sn5D-3gyrA:
undetectable		 1sn5B-3gyrA:
14.26
1sn5D-3gyrA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 524
CYH A 603
HIS A 608
MET A 613
 CU  A1000 (-3.0A)
CU  A1000 (-2.2A)
CU  A1000 (-3.6A)
CU  A1000 (-3.5A)
 0.25A 2fqdA-3gyrA:
37.6		 2fqdA-3gyrA:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 524
CYH A 603
HIS A 608
MET A 613
 CU  A1000 (-3.0A)
CU  A1000 (-2.2A)
CU  A1000 (-3.6A)
CU  A1000 (-3.5A)
 0.28A 2fqeA-3gyrA:
37.3		 2fqeA-3gyrA:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 161
HIS A 163
HIS A 527
HIS A 529
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
 0.30A 2fqeA-3gyrA:
37.3		 2fqeA-3gyrA:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 527
HIS A 529
HIS A 161
HIS A 163
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
 0.87A 2fqeA-3gyrA:
37.3		 2fqeA-3gyrA:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 524
CYH A 603
HIS A 608
MET A 613
 CU  A1000 (-3.0A)
CU  A1000 (-2.2A)
CU  A1000 (-3.6A)
CU  A1000 (-3.5A)
 0.29A 2fqfA-3gyrA:
37.3		 2fqfA-3gyrA:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 161
HIS A 163
HIS A 527
HIS A 529
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
 0.21A 2fqfA-3gyrA:
37.3		 2fqfA-3gyrA:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 527
HIS A 529
HIS A 161
HIS A 163
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
 0.83A 2fqfA-3gyrA:
37.3		 2fqfA-3gyrA:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 524
CYH A 603
HIS A 608
MET A 613
 CU  A1000 (-3.0A)
CU  A1000 (-2.2A)
CU  A1000 (-3.6A)
CU  A1000 (-3.5A)
 0.30A 2fqgA-3gyrA:
37.4		 2fqgA-3gyrA:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 161
HIS A 163
HIS A 527
HIS A 529
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
 0.15A 2fqgA-3gyrA:
37.4		 2fqgA-3gyrA:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 161
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 1.34A 2fqgA-3gyrA:
37.4		 2fqgA-3gyrA:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 527
HIS A 529
HIS A 161
HIS A 163
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
 0.81A 2fqgA-3gyrA:
37.4		 2fqgA-3gyrA:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 6 LEU A 241
LEU A 308
ILE A 239
ARG A 307
 None
 1.01A 2rlfC-3gyrA:
undetectable
2rlfD-3gyrA:
undetectable		 2rlfC-3gyrA:
6.05
2rlfD-3gyrA:
6.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 8 PHE A 283
ASN A 137
SER A 279
ALA A 135
 None
 0.90A 2v7uA-3gyrA:
undetectable		 2v7uA-3gyrA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		3 / 3 HIS A 602
HIS A 604
HIS A 527
 C2O  A1002 (-3.4A)
C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
 0.70A 2w0qA-3gyrA:
undetectable		 2w0qA-3gyrA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 6 PRO A 155
ILE A 113
ASN A 211
LEU A 216
 None
 1.25A 2wekB-3gyrA:
undetectable		 2wekB-3gyrA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 524
CYH A 603
HIS A 608
MET A 613
 CU  A1000 (-3.0A)
CU  A1000 (-2.2A)
CU  A1000 (-3.6A)
CU  A1000 (-3.5A)
 0.66A 2xxgA-3gyrA:
21.2		 2xxgA-3gyrA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 524
CYH A 603
HIS A 608
MET A 613
 CU  A1000 (-3.0A)
CU  A1000 (-2.2A)
CU  A1000 (-3.6A)
CU  A1000 (-3.5A)
 0.71A 2xxgC-3gyrA:
21.2		 2xxgC-3gyrA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_1
(PUTATIVE
MODIFICATION
METHYLASE)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		3 / 3 ASP A 323
THR A  42
GLU A 407
 None
 0.73A 2zifB-3gyrA:
undetectable		 2zifB-3gyrA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 9 PRO A  93
VAL A  92
GLY A  90
ILE A 113
GLY A 215
 None
 1.35A 3csjB-3gyrA:
undetectable		 3csjB-3gyrA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 7 TYR A 200
ILE A  67
GLY A  94
LEU A 162
 None
 0.88A 3elzA-3gyrA:
undetectable		 3elzA-3gyrA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 11 GLY A 386
GLY A 398
ASP A 395
ALA A 389
ALA A 391
 None
 1.05A 3g88A-3gyrA:
undetectable		 3g88A-3gyrA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 11 GLY A 386
GLY A 398
ASP A 395
ALA A 389
ALA A 391
 None
 1.05A 3g88B-3gyrA:
undetectable		 3g88B-3gyrA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 12 GLY A 386
GLY A 398
ASP A 395
ALA A 389
ALA A 391
 None
 1.07A 3g8bB-3gyrA:
undetectable		 3g8bB-3gyrA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_B_EAAB222_1
(GLUTATHIONE
S-TRANSFERASE P)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 9 PHE A 516
VAL A 580
VAL A 588
TRP A 514
GLY A 585
 None
 1.50A 3km6B-3gyrA:
undetectable		 3km6B-3gyrA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 12 LEU A 523
VAL A 320
ALA A 361
LEU A 308
ILE A 243
 None
 1.01A 3ku1H-3gyrA:
undetectable		 3ku1H-3gyrA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 6 TYR A 189
HIS A 161
THR A 160
VAL A 159
 None
CU  A1004 ( 3.2A)
None
None
 1.09A 3lb3A-3gyrA:
undetectable		 3lb3A-3gyrA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 6 TYR A 189
HIS A 161
THR A 160
VAL A 159
 None
CU  A1004 ( 3.2A)
None
None
 1.06A 3lb3B-3gyrA:
undetectable		 3lb3B-3gyrA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		3 / 3 HIS A 602
HIS A 527
HIS A 529
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
 0.77A 3mihA-3gyrA:
undetectable		 3mihA-3gyrA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		3 / 3 TYR A 304
GLY A 302
ASP A 417
 None
 0.64A 3ou6C-3gyrA:
undetectable		 3ou6C-3gyrA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		3 / 3 HIS A 203
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.22A 3qpkA-3gyrA:
22.4		 3qpkA-3gyrA:
25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA603_0
(LACCASE-1)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 163
TRP A 199
HIS A 201
HIS A 604
 C2O  A1002 (-3.3A)
None
C2O  A1002 (-3.7A)
C2O  A1002 (-3.9A)
 0.29A 3qpkA-3gyrA:
22.5		 3qpkA-3gyrA:
25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA604_0
(LACCASE-1)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 161
HIS A 163
HIS A 527
HIS A 529
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
 0.26A 3qpkA-3gyrA:
22.4		 3qpkA-3gyrA:
25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA604_0
(LACCASE-1)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 527
HIS A 529
HIS A 161
HIS A 163
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
 0.88A 3qpkA-3gyrA:
22.4		 3qpkA-3gyrA:
25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		3 / 3 HIS A 203
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.22A 3qpkB-3gyrA:
22.5		 3qpkB-3gyrA:
25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB603_0
(LACCASE-1)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 163
TRP A 199
HIS A 201
HIS A 604
 C2O  A1002 (-3.3A)
None
C2O  A1002 (-3.7A)
C2O  A1002 (-3.9A)
 0.31A 3qpkB-3gyrA:
22.5		 3qpkB-3gyrA:
25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 161
HIS A 163
HIS A 527
HIS A 529
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
 0.21A 3qpkB-3gyrA:
22.5		 3qpkB-3gyrA:
25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 161
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 1.25A 3qpkB-3gyrA:
22.5		 3qpkB-3gyrA:
25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 527
HIS A 529
HIS A 161
HIS A 163
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
 0.85A 3qpkB-3gyrA:
22.5		 3qpkB-3gyrA:
25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		3 / 3 TYR A 220
LEU A 368
ARG A 365
 None
 0.80A 3sufB-3gyrA:
undetectable		 3sufB-3gyrA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 6 HIS A 163
ASP A 224
ASP A 339
GLU A 227
 C2O  A1002 (-3.3A)
None
None
None
 1.33A 3vywA-3gyrA:
undetectable		 3vywA-3gyrA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_1
(MNMC2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 6 GLY A 164
ASP A 224
ASP A 339
GLU A 227
 None
 0.79A 3vywC-3gyrA:
undetectable		 3vywC-3gyrA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 12 VAL A 588
GLU A 461
TYR A 601
HIS A 527
VAL A 580
 None
None
None
CU  A1004 ( 3.2A)
None
 1.17A 4a97B-3gyrA:
undetectable
4a97C-3gyrA:
undetectable		 4a97B-3gyrA:
19.90
4a97C-3gyrA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B9Z_A_ACRA1818_1
(ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 12 LEU A 421
LEU A 232
GLU A 227
ARG A 305
ASP A 367
 None
 1.47A 4b9zA-3gyrA:
undetectable		 4b9zA-3gyrA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 524
CYH A 603
HIS A 608
MET A 613
 CU  A1000 (-3.0A)
CU  A1000 (-2.2A)
CU  A1000 (-3.6A)
CU  A1000 (-3.5A)
 0.30A 4ef3A-3gyrA:
37.2		 4ef3A-3gyrA:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 163
HIS A 201
HIS A 527
HIS A 604
 C2O  A1002 (-3.3A)
C2O  A1002 (-3.7A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.9A)
 0.30A 4ef3A-3gyrA:
37.2		 4ef3A-3gyrA:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 529
HIS A 602
HIS A 161
HIS A 203
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.72A 4ef3A-3gyrA:
37.2		 4ef3A-3gyrA:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1003_0
(BLUE COPPER OXIDASE
CUEO)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 5 HIS A 161
HIS A 203
HIS A 527
HIS A 529
HIS A 602
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.25A 4ef3A-3gyrA:
37.2		 4ef3A-3gyrA:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1003_0
(BLUE COPPER OXIDASE
CUEO)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 5 HIS A 527
HIS A 604
HIS A 161
HIS A 163
HIS A 201
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
C2O  A1002 (-3.7A)
 0.71A 4ef3A-3gyrA:
37.2		 4ef3A-3gyrA:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1004_0
(BLUE COPPER OXIDASE
CUEO)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 161
HIS A 163
HIS A 527
HIS A 529
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
 0.16A 4ef3A-3gyrA:
37.2		 4ef3A-3gyrA:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1004_0
(BLUE COPPER OXIDASE
CUEO)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 527
HIS A 529
HIS A 161
HIS A 163
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
 0.84A 4ef3A-3gyrA:
37.2		 4ef3A-3gyrA:
27.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 201
GLU A 607
HIS A 262
LEU A 154
 C2O  A1002 (-3.7A)
None
None
None
 1.39A 4m2rA-3gyrA:
undetectable		 4m2rA-3gyrA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA3_L_ACTL301_0
(C2095 HEAVY CHAIN
C2095 LIGHT CHAIN)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		3 / 3 PRO A 521
ASN A 518
HIS A 524
 None
None
CU  A1000 (-3.0A)
 1.00A 4ma3H-3gyrA:
undetectable
4ma3L-3gyrA:
2.0		 4ma3H-3gyrA:
16.20
4ma3L-3gyrA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 12 ALA A 360
GLN A 197
ILE A 243
LEU A 368
GLN A 335
 None
 1.24A 4r38B-3gyrA:
undetectable		 4r38B-3gyrA:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 GLY A 483
LEU A 519
PHE A 546
ILE A 479
 None
 0.81A 4xv2A-3gyrA:
undetectable		 4xv2A-3gyrA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 TYR A 402
GLY A  39
TYR A 286
GLY A 258
 None
 0.86A 5ayfA-3gyrA:
undetectable		 5ayfA-3gyrA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_1
(DIHYDROFOLATE
REDUCTASE)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		3 / 3 ASP A 371
ARG A 327
ARG A 378
 None
 0.96A 5eajB-3gyrA:
undetectable		 5eajB-3gyrA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA501_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 5 HIS A 161
HIS A 203
HIS A 527
HIS A 529
HIS A 602
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.20A 5mejA-3gyrA:
26.0		 5mejA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA501_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 5 HIS A 527
HIS A 604
HIS A 161
HIS A 163
HIS A 201
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
C2O  A1002 (-3.7A)
 0.70A 5mejA-3gyrA:
26.0		 5mejA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA502_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		6 / 6 HIS A 161
HIS A 163
TRP A 199
HIS A 201
HIS A 527
HIS A 604
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
None
C2O  A1002 (-3.7A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.9A)
 0.34A 5mejA-3gyrA:
26.0		 5mejA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA502_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 6 HIS A 161
HIS A 203
HIS A 527
HIS A 602
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.77A 5mejA-3gyrA:
26.0		 5mejA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA502_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 6 HIS A 527
HIS A 529
HIS A 602
HIS A 161
HIS A 203
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.68A 5mejA-3gyrA:
26.0		 5mejA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA503_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 161
HIS A 163
HIS A 527
HIS A 529
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
 0.18A 5mejA-3gyrA:
26.0		 5mejA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA503_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 161
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 1.23A 5mejA-3gyrA:
26.0		 5mejA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA503_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 527
HIS A 529
HIS A 161
HIS A 163
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
 0.81A 5mejA-3gyrA:
26.0		 5mejA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA501_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 5 HIS A 161
HIS A 203
HIS A 527
HIS A 529
HIS A 602
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.20A 5mewA-3gyrA:
26.1		 5mewA-3gyrA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA501_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 5 HIS A 527
HIS A 604
HIS A 161
HIS A 163
HIS A 201
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
C2O  A1002 (-3.7A)
 0.67A 5mewA-3gyrA:
26.1		 5mewA-3gyrA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA502_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		6 / 6 HIS A 161
HIS A 163
TRP A 199
HIS A 201
HIS A 527
HIS A 604
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
None
C2O  A1002 (-3.7A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.9A)
 0.34A 5mewA-3gyrA:
26.1		 5mewA-3gyrA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA502_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 6 HIS A 161
HIS A 203
HIS A 527
HIS A 602
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.77A 5mewA-3gyrA:
26.1		 5mewA-3gyrA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA502_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 6 HIS A 527
HIS A 529
HIS A 602
HIS A 161
HIS A 203
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.69A 5mewA-3gyrA:
26.1		 5mewA-3gyrA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA503_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 161
HIS A 163
HIS A 527
HIS A 529
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
 0.18A 5mewA-3gyrA:
26.1		 5mewA-3gyrA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA503_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 161
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 1.23A 5mewA-3gyrA:
26.1		 5mewA-3gyrA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA503_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 527
HIS A 529
HIS A 161
HIS A 163
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
 0.81A 5mewA-3gyrA:
26.1		 5mewA-3gyrA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA501_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 5 HIS A 161
HIS A 203
HIS A 527
HIS A 529
HIS A 602
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.20A 5mhuA-3gyrA:
26.0		 5mhuA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA501_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 5 HIS A 527
HIS A 604
HIS A 161
HIS A 163
HIS A 201
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
C2O  A1002 (-3.7A)
 0.67A 5mhuA-3gyrA:
26.0		 5mhuA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA502_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		6 / 6 HIS A 161
HIS A 163
TRP A 199
HIS A 201
HIS A 527
HIS A 604
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
None
C2O  A1002 (-3.7A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.9A)
 0.34A 5mhuA-3gyrA:
26.0		 5mhuA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA502_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 6 HIS A 161
HIS A 203
HIS A 527
HIS A 602
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.78A 5mhuA-3gyrA:
26.0		 5mhuA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA502_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 6 HIS A 527
HIS A 529
HIS A 602
HIS A 161
HIS A 203
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.69A 5mhuA-3gyrA:
26.0		 5mhuA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA503_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 161
HIS A 163
HIS A 527
HIS A 529
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
 0.17A 5mhuA-3gyrA:
26.0		 5mhuA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA503_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 161
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 1.25A 5mhuA-3gyrA:
26.0		 5mhuA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA503_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 527
HIS A 529
HIS A 161
HIS A 163
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
 0.81A 5mhuA-3gyrA:
26.0		 5mhuA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA501_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 5 HIS A 161
HIS A 203
HIS A 527
HIS A 529
HIS A 602
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.20A 5mhvA-3gyrA:
26.1		 5mhvA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA501_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 5 HIS A 527
HIS A 604
HIS A 161
HIS A 163
HIS A 201
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
C2O  A1002 (-3.7A)
 0.67A 5mhvA-3gyrA:
26.1		 5mhvA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA502_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		6 / 6 HIS A 161
HIS A 163
TRP A 199
HIS A 201
HIS A 527
HIS A 604
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
None
C2O  A1002 (-3.7A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.9A)
 0.34A 5mhvA-3gyrA:
26.1		 5mhvA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA502_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 6 HIS A 161
HIS A 203
HIS A 527
HIS A 602
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.78A 5mhvA-3gyrA:
26.1		 5mhvA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA502_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 6 HIS A 527
HIS A 529
HIS A 602
HIS A 161
HIS A 203
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.69A 5mhvA-3gyrA:
26.1		 5mhvA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA503_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 161
HIS A 163
HIS A 527
HIS A 529
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
 0.17A 5mhvA-3gyrA:
26.1		 5mhvA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA503_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 161
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 1.25A 5mhvA-3gyrA:
26.1		 5mhvA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA503_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 527
HIS A 529
HIS A 161
HIS A 163
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
 0.81A 5mhvA-3gyrA:
26.1		 5mhvA-3gyrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 527
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.17A 5mhwA-3gyrA:
26.1		 5mhwA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 604
HIS A 161
HIS A 163
HIS A 201
 C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
C2O  A1002 (-3.7A)
 0.68A 5mhwA-3gyrA:
26.1		 5mhwA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 5 HIS A 161
HIS A 163
TRP A 199
HIS A 201
HIS A 604
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
None
C2O  A1002 (-3.7A)
C2O  A1002 (-3.9A)
 0.34A 5mhwA-3gyrA:
26.1		 5mhwA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 527
HIS A 529
HIS A 602
HIS A 203
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
C2O  A1002 (-3.4A)
 0.73A 5mhwA-3gyrA:
26.1		 5mhwA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 604
HIS A 527
HIS A 602
HIS A 529
 C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
 0.91A 5mhwA-3gyrA:
26.1		 5mhwA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 161
HIS A 163
HIS A 527
HIS A 529
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
 0.17A 5mhwA-3gyrA:
26.1		 5mhwA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 161
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 1.26A 5mhwA-3gyrA:
26.1		 5mhwA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 527
HIS A 529
HIS A 161
HIS A 163
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
 0.81A 5mhwA-3gyrA:
26.1		 5mhwA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 527
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.17A 5mhxA-3gyrA:
26.0		 5mhxA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 604
HIS A 161
HIS A 163
HIS A 201
 C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
C2O  A1002 (-3.7A)
 0.69A 5mhxA-3gyrA:
26.0		 5mhxA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 5 HIS A 161
HIS A 163
TRP A 199
HIS A 201
HIS A 604
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
None
C2O  A1002 (-3.7A)
C2O  A1002 (-3.9A)
 0.35A 5mhxA-3gyrA:
26.0		 5mhxA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 527
HIS A 529
HIS A 602
HIS A 203
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
C2O  A1002 (-3.4A)
 0.73A 5mhxA-3gyrA:
26.0		 5mhxA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 604
HIS A 527
HIS A 602
HIS A 529
 C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
 0.91A 5mhxA-3gyrA:
26.0		 5mhxA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 161
HIS A 163
HIS A 527
HIS A 529
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
 0.17A 5mhxA-3gyrA:
26.0		 5mhxA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 161
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 1.26A 5mhxA-3gyrA:
26.0		 5mhxA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 527
HIS A 529
HIS A 161
HIS A 163
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
 0.82A 5mhxA-3gyrA:
26.0		 5mhxA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 527
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.17A 5mhyA-3gyrA:
26.1		 5mhyA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 604
HIS A 161
HIS A 163
HIS A 201
 C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
C2O  A1002 (-3.7A)
 0.68A 5mhyA-3gyrA:
26.1		 5mhyA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 5 HIS A 161
HIS A 163
TRP A 199
HIS A 201
HIS A 604
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
None
C2O  A1002 (-3.7A)
C2O  A1002 (-3.9A)
 0.35A 5mhyA-3gyrA:
26.1		 5mhyA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 527
HIS A 529
HIS A 602
HIS A 203
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
C2O  A1002 (-3.4A)
 0.73A 5mhyA-3gyrA:
26.1		 5mhyA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 604
HIS A 527
HIS A 602
HIS A 529
 C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
 0.91A 5mhyA-3gyrA:
26.1		 5mhyA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 161
HIS A 163
HIS A 527
HIS A 529
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
 0.17A 5mhyA-3gyrA:
26.1		 5mhyA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 161
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 1.26A 5mhyA-3gyrA:
26.1		 5mhyA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 527
HIS A 529
HIS A 161
HIS A 163
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
 0.82A 5mhyA-3gyrA:
26.1		 5mhyA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 527
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.18A 5mhzA-3gyrA:
26.2		 5mhzA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 604
HIS A 161
HIS A 163
HIS A 201
 C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
C2O  A1002 (-3.7A)
 0.68A 5mhzA-3gyrA:
26.2		 5mhzA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 5 HIS A 161
HIS A 163
TRP A 199
HIS A 201
HIS A 604
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
None
C2O  A1002 (-3.7A)
C2O  A1002 (-3.9A)
 0.35A 5mhzA-3gyrA:
26.2		 5mhzA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 527
HIS A 529
HIS A 602
HIS A 203
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
C2O  A1002 (-3.4A)
 0.74A 5mhzA-3gyrA:
26.2		 5mhzA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 604
HIS A 527
HIS A 602
HIS A 529
 C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
 0.91A 5mhzA-3gyrA:
26.2		 5mhzA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 161
HIS A 163
HIS A 527
HIS A 529
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
 0.17A 5mhzA-3gyrA:
26.2		 5mhzA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 161
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 1.27A 5mhzA-3gyrA:
26.2		 5mhzA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 527
HIS A 529
HIS A 161
HIS A 163
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
 0.82A 5mhzA-3gyrA:
26.2		 5mhzA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 527
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.18A 5mi1A-3gyrA:
26.1		 5mi1A-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 604
HIS A 161
HIS A 163
HIS A 201
 C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
C2O  A1002 (-3.7A)
 0.68A 5mi1A-3gyrA:
26.1		 5mi1A-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 5 HIS A 161
HIS A 163
TRP A 199
HIS A 201
HIS A 604
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
None
C2O  A1002 (-3.7A)
C2O  A1002 (-3.9A)
 0.35A 5mi1A-3gyrA:
26.1		 5mi1A-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 527
HIS A 529
HIS A 602
HIS A 203
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
C2O  A1002 (-3.4A)
 0.74A 5mi1A-3gyrA:
26.1		 5mi1A-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 604
HIS A 527
HIS A 602
HIS A 529
 C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
 0.91A 5mi1A-3gyrA:
26.1		 5mi1A-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 161
HIS A 163
HIS A 527
HIS A 529
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
 0.17A 5mi1A-3gyrA:
26.1		 5mi1A-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 161
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 1.27A 5mi1A-3gyrA:
26.1		 5mi1A-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 527
HIS A 529
HIS A 161
HIS A 163
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
 0.82A 5mi1A-3gyrA:
26.1		 5mi1A-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 527
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.18A 5mi2A-3gyrA:
26.1		 5mi2A-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 604
HIS A 161
HIS A 163
HIS A 201
 C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
C2O  A1002 (-3.7A)
 0.68A 5mi2A-3gyrA:
26.1		 5mi2A-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 5 HIS A 161
HIS A 163
TRP A 199
HIS A 201
HIS A 604
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
None
C2O  A1002 (-3.7A)
C2O  A1002 (-3.9A)
 0.35A 5mi2A-3gyrA:
26.1		 5mi2A-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 527
HIS A 529
HIS A 602
HIS A 203
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
C2O  A1002 (-3.4A)
 0.73A 5mi2A-3gyrA:
26.1		 5mi2A-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 604
HIS A 527
HIS A 602
HIS A 529
 C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
 0.91A 5mi2A-3gyrA:
26.1		 5mi2A-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 161
HIS A 163
HIS A 527
HIS A 529
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
 0.17A 5mi2A-3gyrA:
26.1		 5mi2A-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 161
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 1.26A 5mi2A-3gyrA:
26.1		 5mi2A-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 527
HIS A 529
HIS A 161
HIS A 163
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
 0.82A 5mi2A-3gyrA:
26.1		 5mi2A-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 527
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.18A 5miaA-3gyrA:
26.1		 5miaA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 604
HIS A 161
HIS A 163
HIS A 201
 C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
C2O  A1002 (-3.7A)
 0.67A 5miaA-3gyrA:
26.1		 5miaA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 5 HIS A 161
HIS A 163
TRP A 199
HIS A 201
HIS A 604
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
None
C2O  A1002 (-3.7A)
C2O  A1002 (-3.9A)
 0.35A 5miaA-3gyrA:
26.1		 5miaA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 527
HIS A 529
HIS A 602
HIS A 203
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
C2O  A1002 (-3.4A)
 0.74A 5miaA-3gyrA:
26.1		 5miaA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 604
HIS A 527
HIS A 602
HIS A 529
 C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
 0.91A 5miaA-3gyrA:
26.1		 5miaA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 161
HIS A 163
HIS A 527
HIS A 529
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
 0.17A 5miaA-3gyrA:
26.1		 5miaA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 161
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 1.27A 5miaA-3gyrA:
26.1		 5miaA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 527
HIS A 529
HIS A 161
HIS A 163
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
 0.81A 5miaA-3gyrA:
26.1		 5miaA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 527
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.18A 5mibA-3gyrA:
26.1		 5mibA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 604
HIS A 161
HIS A 163
HIS A 201
 C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
C2O  A1002 (-3.7A)
 0.68A 5mibA-3gyrA:
26.1		 5mibA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 5 HIS A 161
HIS A 163
TRP A 199
HIS A 201
HIS A 604
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
None
C2O  A1002 (-3.7A)
C2O  A1002 (-3.9A)
 0.35A 5mibA-3gyrA:
26.1		 5mibA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 527
HIS A 529
HIS A 602
HIS A 203
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
C2O  A1002 (-3.4A)
 0.74A 5mibA-3gyrA:
26.1		 5mibA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 604
HIS A 527
HIS A 602
HIS A 529
 C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
 0.91A 5mibA-3gyrA:
26.1		 5mibA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 161
HIS A 163
HIS A 527
HIS A 529
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
 0.17A 5mibA-3gyrA:
26.1		 5mibA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 161
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 1.27A 5mibA-3gyrA:
26.1		 5mibA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 527
HIS A 529
HIS A 161
HIS A 163
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
 0.82A 5mibA-3gyrA:
26.1		 5mibA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 527
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.18A 5micA-3gyrA:
26.1		 5micA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 604
HIS A 161
HIS A 163
HIS A 201
 C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
C2O  A1002 (-3.7A)
 0.68A 5micA-3gyrA:
26.1		 5micA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 5 HIS A 161
HIS A 163
TRP A 199
HIS A 201
HIS A 604
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
None
C2O  A1002 (-3.7A)
C2O  A1002 (-3.9A)
 0.35A 5micA-3gyrA:
26.1		 5micA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 527
HIS A 529
HIS A 602
HIS A 203
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
C2O  A1002 (-3.4A)
 0.74A 5micA-3gyrA:
26.1		 5micA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 604
HIS A 527
HIS A 602
HIS A 529
 C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
 0.92A 5micA-3gyrA:
26.1		 5micA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 161
HIS A 163
HIS A 527
HIS A 529
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
 0.17A 5micA-3gyrA:
26.1		 5micA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 161
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 1.27A 5micA-3gyrA:
26.1		 5micA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 527
HIS A 529
HIS A 161
HIS A 163
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
 0.82A 5micA-3gyrA:
26.1		 5micA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 527
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.18A 5midA-3gyrA:
26.0		 5midA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 604
HIS A 161
HIS A 163
HIS A 201
 C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
C2O  A1002 (-3.7A)
 0.68A 5midA-3gyrA:
26.0		 5midA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 5 HIS A 161
HIS A 163
TRP A 199
HIS A 201
HIS A 604
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
None
C2O  A1002 (-3.7A)
C2O  A1002 (-3.9A)
 0.35A 5midA-3gyrA:
26.0		 5midA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 527
HIS A 529
HIS A 602
HIS A 203
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
C2O  A1002 (-3.4A)
 0.74A 5midA-3gyrA:
26.0		 5midA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 604
HIS A 527
HIS A 602
HIS A 529
 C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
 0.92A 5midA-3gyrA:
26.0		 5midA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 161
HIS A 163
HIS A 527
HIS A 529
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
 0.18A 5midA-3gyrA:
26.0		 5midA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 161
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 1.27A 5midA-3gyrA:
26.0		 5midA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 527
HIS A 529
HIS A 161
HIS A 163
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
 0.82A 5midA-3gyrA:
26.0		 5midA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 527
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.19A 5mieA-3gyrA:
26.1		 5mieA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 604
HIS A 161
HIS A 163
HIS A 201
 C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
C2O  A1002 (-3.7A)
 0.68A 5mieA-3gyrA:
26.1		 5mieA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 5 HIS A 161
HIS A 163
TRP A 199
HIS A 201
HIS A 604
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
None
C2O  A1002 (-3.7A)
C2O  A1002 (-3.9A)
 0.35A 5mieA-3gyrA:
26.1		 5mieA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 527
HIS A 529
HIS A 602
HIS A 203
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
C2O  A1002 (-3.4A)
 0.74A 5mieA-3gyrA:
26.1		 5mieA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 604
HIS A 527
HIS A 602
HIS A 529
 C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
 0.92A 5mieA-3gyrA:
26.1		 5mieA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 161
HIS A 163
HIS A 527
HIS A 529
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
 0.17A 5mieA-3gyrA:
26.1		 5mieA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 161
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 1.27A 5mieA-3gyrA:
26.1		 5mieA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 527
HIS A 529
HIS A 161
HIS A 163
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
 0.82A 5mieA-3gyrA:
26.1		 5mieA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		3 / 3 HIS A 203
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 0.20A 5migA-3gyrA:
26.2		 5migA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 5 HIS A 161
HIS A 163
TRP A 199
HIS A 201
HIS A 604
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
None
C2O  A1002 (-3.7A)
C2O  A1002 (-3.9A)
 0.36A 5migA-3gyrA:
26.2		 5migA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 527
HIS A 529
HIS A 602
HIS A 203
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
C2O  A1002 (-3.4A)
 0.74A 5migA-3gyrA:
26.2		 5migA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 HIS A 604
HIS A 527
HIS A 602
HIS A 529
 C2O  A1002 (-3.9A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
 0.92A 5migA-3gyrA:
26.2		 5migA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 161
HIS A 163
HIS A 527
HIS A 529
 CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
 0.18A 5migA-3gyrA:
26.2		 5migA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 203
HIS A 161
HIS A 529
HIS A 602
 C2O  A1002 (-3.4A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.4A)
 1.27A 5migA-3gyrA:
26.2		 5migA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA603_0
(LACCASE 2)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 HIS A 527
HIS A 529
HIS A 161
HIS A 163
 CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
CU  A1004 ( 3.2A)
C2O  A1002 (-3.3A)
 0.81A 5migA-3gyrA:
26.2		 5migA-3gyrA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA307_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 ASP A 384
PRO A  43
GLU A  40
ARG A 401
 None
 1.17A 5uxcA-3gyrA:
undetectable		 5uxcA-3gyrA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW9_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 8 GLY A 168
ALA A 595
GLY A 170
GLU A 188
SER A 187
 None
 1.33A 5vw9A-3gyrA:
undetectable		 5vw9A-3gyrA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		3 / 3 ARG A 615
PHE A 599
LEU A 502
 None
 0.86A 5x1bC-3gyrA:
undetectable		 5x1bC-3gyrA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA503_1
(CYTOCHROME P450 2C9)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 5 PRO A 448
GLY A 449
THR A 450
LYS A 451
 None
 1.08A 5x23A-3gyrA:
undetectable		 5x23A-3gyrA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA503_1
(CYTOCHROME P450 2C9)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 6 PRO A 448
GLY A 449
THR A 450
LYS A 451
 None
 0.99A 5x24A-3gyrA:
undetectable		 5x24A-3gyrA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_1
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		3 / 3 THR A 208
GLU A 609
HIS A 529
 None
C2O  A1002 ( 4.8A)
CU  A1004 ( 3.2A)
 0.90A 5xioA-3gyrA:
undetectable		 5xioA-3gyrA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		3 / 3 THR A 208
GLU A 609
HIS A 529
 None
C2O  A1002 ( 4.8A)
CU  A1004 ( 3.2A)
 0.90A 5xiqD-3gyrA:
undetectable		 5xiqD-3gyrA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_1
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		5 / 12 LEU A 260
VAL A 121
GLY A 215
VAL A  92
LEU A  76
 None
 0.95A 5xv7A-3gyrA:
undetectable		 5xv7A-3gyrA:
8.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA502_1
(CYTOCHROME P450 2C9)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 6 PRO A 448
GLY A 449
THR A 450
LYS A 451
 None
 1.09A 5xxiA-3gyrA:
undetectable		 5xxiA-3gyrA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 6 ASP A 339
GLN A 335
ASN A 570
LEU A 368
 None
None
GOL  A5001 (-2.9A)
None
 1.11A 6ekuA-3gyrA:
undetectable		 6ekuA-3gyrA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 6 GLU A 512
ARG A 441
PHE A 504
VAL A 618
 None
 1.23A 6fgdA-3gyrA:
undetectable		 6fgdA-3gyrA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 3gyr PHENOXAZINONE
SYNTHASE
(Streptomyces
antibioticus) 		4 / 4 ARG A 305
GLU A 238
GLU A 227
ARG A 223
 None
 1.31A 6fk2A-3gyrA:
undetectable		 6fk2A-3gyrA:
12.08