SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gyw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3gyw NUCLEOSOME ASSEMBLY
PROTEIN 1, PUTATIVE
(Plasmodium
falciparum) 		4 / 5 PHE A 150
LEU A 107
PHE A 229
SER A 224
 None
 1.37A 1wrkB-3gywA:
undetectable		 1wrkB-3gywA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XMU_A_ROFA101_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 3gyw NUCLEOSOME ASSEMBLY
PROTEIN 1, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP A 121
LEU A 125
ILE A 188
SER A 161
PHE A 152
 None
 1.28A 1xmuA-3gywA:
undetectable		 1xmuA-3gywA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOM_A_CIOA603_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3gyw NUCLEOSOME ASSEMBLY
PROTEIN 1, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP A 121
LEU A 125
ILE A 188
SER A 161
PHE A 152
 None
 1.19A 1xomA-3gywA:
undetectable		 1xomA-3gywA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3gyw NUCLEOSOME ASSEMBLY
PROTEIN 1, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP A 121
LEU A 125
ILE A 188
SER A 161
PHE A 152
 None
 1.19A 1xoqA-3gywA:
undetectable		 1xoqA-3gywA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3gyw NUCLEOSOME ASSEMBLY
PROTEIN 1, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP A 121
LEU A 125
ILE A 188
SER A 161
PHE A 152
 None
 1.20A 1xoqB-3gywA:
undetectable		 1xoqB-3gywA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O0M_A_ACTA146_0
(HIT FAMILY PROTEIN)		 3gyw NUCLEOSOME ASSEMBLY
PROTEIN 1, PUTATIVE
(Plasmodium
falciparum) 		4 / 4 ASP A 119
GLU A 118
GLU A 122
ARG A 108
 None
 1.44A 3o0mA-3gywA:
0.1		 3o0mA-3gywA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3gyw NUCLEOSOME ASSEMBLY
PROTEIN 1, PUTATIVE
(Plasmodium
falciparum) 		4 / 7 ASP A 134
ARG A 132
TYR A 151
ASP A  80
 None
 1.17A 6mn5B-3gywA:
undetectable		 6mn5B-3gywA:
14.07