SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gyx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BRP_A_RTLA183_0
(RETINOL BINDING
PROTEIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		5 / 12 PHE A 496
ALA A 224
MET A 227
GLY A 456
PHE A 500
 None
 1.22A 1brpA-3gyxA:
undetectable		 1brpA-3gyxA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_0
(FTSJ)		 3gyx ADENYLYLSULFATE
REDUCTASE
ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas;
Desulfovibrio
gigas) 		6 / 12 GLY A 388
PRO B   2
GLY A 248
TRP B  48
PHE A 382
LEU A 383
 None
 1.29A 1eizA-3gyxA:
2.2		 1eizA-3gyxA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		3 / 3 ALA A 234
VAL A 254
TRP A 255
 None
 0.96A 1gmkA-3gyxA:
undetectable
1gmkB-3gyxA:
undetectable		 1gmkA-3gyxA:
2.61
1gmkB-3gyxA:
2.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		3 / 4 VAL A 254
TRP A 251
TRP A 255
 None
FAD  A1000 (-3.7A)
None
 1.19A 1gmkA-3gyxA:
undetectable
1gmkB-3gyxA:
undetectable		 1gmkA-3gyxA:
2.61
1gmkB-3gyxA:
2.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		3 / 4 VAL A 254
TRP A 251
TRP A 255
 None
FAD  A1000 (-3.7A)
None
 0.97A 1gmkC-3gyxA:
undetectable
1gmkD-3gyxA:
undetectable		 1gmkC-3gyxA:
2.61
1gmkD-3gyxA:
2.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9J_H_TESH1010_1
(RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT HEAVY
CHAIN
RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT LIGHT
CHAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		5 / 11 SER A 472
VAL A 117
TYR A  80
GLY A 167
LEU A  74
 FAD  A1000 (-2.7A)
None
None
None
FAD  A1000 (-3.9A)
 1.27A 1i9jH-3gyxA:
undetectable
1i9jL-3gyxA:
undetectable		 1i9jH-3gyxA:
16.33
1i9jL-3gyxA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		3 / 3 ASP A 579
LEU A 572
LEU A 576
 None
 0.65A 1ikeA-3gyxA:
undetectable		 1ikeA-3gyxA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		5 / 9 SER A 242
GLY A 246
ALA B  71
LEU A 392
GLY A 286
 None
 1.16A 1jb0A-3gyxA:
undetectable		 1jb0A-3gyxA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.36A 1k2sA-3gyxB:
undetectable
1k2sB-3gyxB:
undetectable		 1k2sA-3gyxB:
16.46
1k2sB-3gyxB:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 1k2tA-3gyxA:
2.9
1k2tB-3gyxA:
undetectable		 1k2tA-3gyxA:
21.08
1k2tB-3gyxA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.30A 1k2tA-3gyxB:
undetectable
1k2tB-3gyxB:
undetectable		 1k2tA-3gyxB:
16.46
1k2tB-3gyxB:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		5 / 12 ILE A 173
ALA A  62
SER A  63
TRP A 255
GLY A  73
 None
FAD  A1000 ( 4.3A)
None
None
None
 1.08A 1kiaA-3gyxA:
undetectable		 1kiaA-3gyxA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.32A 1lzxA-3gyxB:
undetectable
1lzxB-3gyxB:
undetectable		 1lzxA-3gyxB:
16.46
1lzxB-3gyxB:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 1lzzA-3gyxA:
0.0
1lzzB-3gyxA:
undetectable		 1lzzA-3gyxA:
21.08
1lzzB-3gyxA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.34A 1m00A-3gyxA:
undetectable
1m00B-3gyxA:
undetectable		 1m00A-3gyxA:
21.08
1m00B-3gyxA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 1m00A-3gyxB:
undetectable
1m00B-3gyxB:
undetectable		 1m00A-3gyxB:
16.46
1m00B-3gyxB:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.33A 1mmvA-3gyxA:
undetectable
1mmvB-3gyxA:
undetectable		 1mmvA-3gyxA:
21.08
1mmvB-3gyxA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.33A 1mmvA-3gyxB:
undetectable
1mmvB-3gyxB:
undetectable		 1mmvA-3gyxB:
16.46
1mmvB-3gyxB:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		3 / 3 PHE A 613
TRP A 636
GLU A 616
 None
 0.89A 1mogA-3gyxA:
undetectable		 1mogA-3gyxA:
7.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		3 / 3 PHE A 639
TRP A 425
GLU A 270
 None
 1.15A 1mogA-3gyxA:
undetectable		 1mogA-3gyxA:
7.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 1om4A-3gyxA:
0.0
1om4B-3gyxA:
undetectable		 1om4A-3gyxA:
20.98
1om4B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 1om4A-3gyxB:
undetectable
1om4B-3gyxB:
undetectable		 1om4A-3gyxB:
16.67
1om4B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.30A 1om5A-3gyxB:
undetectable
1om5B-3gyxB:
undetectable		 1om5A-3gyxB:
16.67
1om5B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.29A 1p6jA-3gyxA:
undetectable
1p6jB-3gyxA:
undetectable		 1p6jA-3gyxA:
21.01
1p6jB-3gyxA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 1p6jA-3gyxB:
undetectable
1p6jB-3gyxB:
undetectable		 1p6jA-3gyxB:
16.67
1p6jB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 1p6kA-3gyxA:
0.0
1p6kB-3gyxA:
undetectable		 1p6kA-3gyxA:
20.33
1p6kB-3gyxA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.32A 1p6kA-3gyxB:
undetectable
1p6kB-3gyxB:
undetectable		 1p6kA-3gyxB:
16.67
1p6kB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 8 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 1rs6A-3gyxB:
undetectable
1rs6B-3gyxB:
undetectable		 1rs6A-3gyxB:
16.67
1rs6B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.24A 1rs7A-3gyxA:
undetectable
1rs7B-3gyxA:
undetectable		 1rs7A-3gyxA:
21.01
1rs7B-3gyxA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 1rs7A-3gyxB:
undetectable
1rs7B-3gyxB:
undetectable		 1rs7A-3gyxB:
16.67
1rs7B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 3gyx ADENYLYLSULFATE
REDUCTASE
ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas;
Desulfovibrio
gigas) 		3 / 3 ALA A 257
VAL A 254
TRP B  48
 None
 0.89A 1tkqB-3gyxA:
undetectable		 1tkqB-3gyxA:
2.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		3 / 3 ARG A 282
SER B  52
TYR B  51
 None
SF4  B1000 ( 4.6A)
None
 0.70A 1x70A-3gyxA:
undetectable		 1x70A-3gyxA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XPQ_A_SPMA924_1
(FMS1 PROTEIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		5 / 11 ASP A  96
PHE A 278
LEU A 341
PHE A 622
CYH A 310
 None
 1.46A 1xpqA-3gyxA:
13.7		 1xpqA-3gyxA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.35A 1zzqA-3gyxA:
undetectable
1zzqB-3gyxA:
undetectable		 1zzqA-3gyxA:
20.36
1zzqB-3gyxA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.33A 1zzqA-3gyxB:
undetectable
1zzqB-3gyxB:
undetectable		 1zzqA-3gyxB:
16.46
1zzqB-3gyxB:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.30A 2g6hA-3gyxB:
undetectable
2g6hB-3gyxB:
undetectable		 2g6hA-3gyxB:
16.46
2g6hB-3gyxB:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 2g6kA-3gyxB:
undetectable
2g6kB-3gyxB:
undetectable		 2g6kA-3gyxB:
16.46
2g6kB-3gyxB:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.32A 2g6mA-3gyxB:
undetectable
2g6mB-3gyxB:
undetectable		 2g6mA-3gyxB:
16.46
2g6mB-3gyxB:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 GLY A 152
ASP A 153
ASN A 151
ASP A 131
 None
 1.04A 2g72B-3gyxA:
undetectable		 2g72B-3gyxA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.25A 2hx3A-3gyxB:
undetectable
2hx3B-3gyxB:
undetectable		 2hx3A-3gyxB:
16.67
2hx3B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 2hx4A-3gyxA:
undetectable
2hx4B-3gyxA:
undetectable		 2hx4A-3gyxA:
20.98
2hx4B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 2hx4A-3gyxB:
undetectable
2hx4B-3gyxB:
undetectable		 2hx4A-3gyxB:
16.67
2hx4B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		3 / 3 ALA A 178
GLY A  35
SER A  67
 None
FAD  A1000 (-3.3A)
FAD  A1000 (-2.9A)
 0.57A 2ivuA-3gyxA:
undetectable		 2ivuA-3gyxA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.35A 3b3mA-3gyxA:
undetectable
3b3mB-3gyxA:
undetectable		 3b3mA-3gyxA:
20.98
3b3mB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.32A 3b3mA-3gyxB:
undetectable
3b3mB-3gyxB:
undetectable		 3b3mA-3gyxB:
16.67
3b3mB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.28A 3b3nA-3gyxA:
undetectable
3b3nB-3gyxA:
undetectable		 3b3nA-3gyxA:
20.98
3b3nB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 3b3nA-3gyxB:
undetectable
3b3nB-3gyxB:
undetectable		 3b3nA-3gyxB:
16.67
3b3nB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 3b3oA-3gyxA:
undetectable
3b3oB-3gyxA:
undetectable		 3b3oA-3gyxA:
20.98
3b3oB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 3b3oA-3gyxB:
undetectable
3b3oB-3gyxB:
undetectable		 3b3oA-3gyxB:
16.67
3b3oB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.34A 3b3pA-3gyxA:
undetectable
3b3pB-3gyxA:
undetectable		 3b3pA-3gyxA:
20.98
3b3pB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 8 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.26A 3b3pA-3gyxB:
undetectable
3b3pB-3gyxB:
undetectable		 3b3pA-3gyxB:
16.67
3b3pB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.29A 3hsnA-3gyxA:
undetectable
3hsnB-3gyxA:
undetectable		 3hsnA-3gyxA:
20.98
3hsnB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 3hsnA-3gyxB:
undetectable
3hsnB-3gyxB:
undetectable		 3hsnA-3gyxB:
16.67
3hsnB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 3hsoA-3gyxA:
undetectable
3hsoB-3gyxA:
undetectable		 3hsoA-3gyxA:
20.98
3hsoB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.27A 3hsoA-3gyxB:
undetectable
3hsoB-3gyxB:
undetectable		 3hsoA-3gyxB:
16.67
3hsoB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 3hspA-3gyxA:
undetectable
3hspB-3gyxA:
undetectable		 3hspA-3gyxA:
20.98
3hspB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.33A 3jt3A-3gyxA:
undetectable
3jt3B-3gyxA:
undetectable		 3jt3A-3gyxA:
20.98
3jt3B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.27A 3jt3A-3gyxB:
undetectable
3jt3B-3gyxB:
undetectable		 3jt3A-3gyxB:
16.67
3jt3B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.34A 3jt4A-3gyxA:
0.0
3jt4B-3gyxA:
undetectable		 3jt4A-3gyxA:
20.98
3jt4B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 3jt4A-3gyxB:
undetectable
3jt4B-3gyxB:
undetectable		 3jt4A-3gyxB:
16.67
3jt4B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.33A 3jt5A-3gyxA:
undetectable
3jt5B-3gyxA:
undetectable		 3jt5A-3gyxA:
20.98
3jt5B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 3jt5A-3gyxB:
undetectable
3jt5B-3gyxB:
undetectable		 3jt5A-3gyxB:
16.67
3jt5B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.34A 3jt6A-3gyxA:
undetectable
3jt6B-3gyxA:
undetectable		 3jt6A-3gyxA:
20.98
3jt6B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.34A 3jt7A-3gyxA:
undetectable
3jt7B-3gyxA:
undetectable		 3jt7A-3gyxA:
20.98
3jt7B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 3jt7A-3gyxB:
undetectable
3jt7B-3gyxB:
undetectable		 3jt7A-3gyxB:
16.67
3jt7B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.34A 3jt8A-3gyxA:
undetectable
3jt8B-3gyxA:
0.0		 3jt8A-3gyxA:
20.98
3jt8B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.27A 3jt8A-3gyxB:
undetectable
3jt8B-3gyxB:
undetectable		 3jt8A-3gyxB:
16.67
3jt8B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.32A 3jt9A-3gyxB:
undetectable
3jt9B-3gyxB:
undetectable		 3jt9A-3gyxB:
16.67
3jt9B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 3jwsA-3gyxA:
undetectable
3jwsB-3gyxA:
undetectable		 3jwsA-3gyxA:
20.83
3jwsB-3gyxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 3jwsA-3gyxB:
undetectable
3jwsB-3gyxB:
undetectable		 3jwsA-3gyxB:
16.67
3jwsB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 3jwtA-3gyxA:
undetectable
3jwtB-3gyxA:
undetectable		 3jwtA-3gyxA:
20.83
3jwtB-3gyxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 3jwtA-3gyxB:
undetectable
3jwtB-3gyxB:
undetectable		 3jwtA-3gyxB:
16.67
3jwtB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 3jwuA-3gyxA:
undetectable
3jwuB-3gyxA:
undetectable		 3jwuA-3gyxA:
20.83
3jwuB-3gyxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 3jwuA-3gyxB:
undetectable
3jwuB-3gyxB:
undetectable		 3jwuA-3gyxB:
16.67
3jwuB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.29A 3jwvA-3gyxA:
undetectable
3jwvB-3gyxA:
undetectable		 3jwvA-3gyxA:
20.83
3jwvB-3gyxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.27A 3jwvA-3gyxB:
undetectable
3jwvB-3gyxB:
undetectable		 3jwvA-3gyxB:
16.67
3jwvB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.33A 3jx0A-3gyxA:
undetectable
3jx0B-3gyxA:
undetectable		 3jx0A-3gyxA:
20.30
3jx0B-3gyxA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_2
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		3 / 3 ARG A  91
THR A 333
THR A  79
 None
 0.64A 3k2hB-3gyxA:
undetectable		 3k2hB-3gyxA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		3 / 3 TRP A 255
ALA A 257
VAL A 254
 None
 0.92A 3l8lA-3gyxA:
undetectable
3l8lB-3gyxA:
undetectable		 3l8lA-3gyxA:
2.61
3l8lB-3gyxA:
3.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 3n2rA-3gyxA:
undetectable
3n2rB-3gyxA:
undetectable		 3n2rA-3gyxA:
20.98
3n2rB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 3n2rA-3gyxB:
undetectable
3n2rB-3gyxB:
undetectable		 3n2rA-3gyxB:
16.67
3n2rB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.41A 3n5vA-3gyxA:
undetectable
3n5vB-3gyxA:
undetectable		 3n5vA-3gyxA:
20.98
3n5vB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 3n5vA-3gyxB:
undetectable
3n5vB-3gyxB:
undetectable		 3n5vA-3gyxB:
16.67
3n5vB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.35A 3n5yA-3gyxA:
undetectable
3n5yB-3gyxA:
undetectable		 3n5yA-3gyxA:
20.98
3n5yB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 3n5yA-3gyxB:
undetectable
3n5yB-3gyxB:
undetectable		 3n5yA-3gyxB:
16.67
3n5yB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.34A 3n5zA-3gyxA:
undetectable
3n5zB-3gyxA:
undetectable		 3n5zA-3gyxA:
20.98
3n5zB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.30A 3n5zA-3gyxB:
undetectable
3n5zB-3gyxB:
undetectable		 3n5zA-3gyxB:
16.67
3n5zB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.23A 3nljA-3gyxB:
undetectable
3nljB-3gyxB:
undetectable		 3nljA-3gyxB:
19.15
3nljB-3gyxB:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.26A 3nlkA-3gyxA:
undetectable
3nlkB-3gyxA:
undetectable		 3nlkA-3gyxA:
20.83
3nlkB-3gyxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.25A 3nlkA-3gyxB:
undetectable
3nlkB-3gyxB:
undetectable		 3nlkA-3gyxB:
16.67
3nlkB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 3nlmA-3gyxA:
undetectable
3nlmB-3gyxA:
undetectable		 3nlmA-3gyxA:
20.98
3nlmB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.27A 3nlnA-3gyxA:
undetectable
3nlnB-3gyxA:
undetectable		 3nlnA-3gyxA:
20.83
3nlnB-3gyxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.30A 3nlnA-3gyxB:
undetectable
3nlnB-3gyxB:
undetectable		 3nlnA-3gyxB:
16.67
3nlnB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 3nloA-3gyxA:
undetectable
3nloB-3gyxA:
undetectable		 3nloA-3gyxA:
20.83
3nloB-3gyxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 3nloA-3gyxB:
undetectable
3nloB-3gyxB:
undetectable		 3nloA-3gyxB:
16.67
3nloB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 3nlvA-3gyxA:
0.0
3nlvB-3gyxA:
undetectable		 3nlvA-3gyxA:
20.98
3nlvB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 3nlvA-3gyxB:
undetectable
3nlvB-3gyxB:
undetectable		 3nlvA-3gyxB:
16.67
3nlvB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 3nlwA-3gyxA:
undetectable
3nlwB-3gyxA:
undetectable		 3nlwA-3gyxA:
20.98
3nlwB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 3nlwA-3gyxB:
undetectable
3nlwB-3gyxB:
undetectable		 3nlwA-3gyxB:
16.67
3nlwB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.34A 3nlxA-3gyxA:
undetectable
3nlxB-3gyxA:
undetectable		 3nlxA-3gyxA:
20.98
3nlxB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 3nlxA-3gyxB:
undetectable
3nlxB-3gyxB:
undetectable		 3nlxA-3gyxB:
16.67
3nlxB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.33A 3nlyA-3gyxA:
undetectable
3nlyB-3gyxA:
undetectable		 3nlyA-3gyxA:
20.98
3nlyB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 8 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.27A 3nlyA-3gyxB:
undetectable
3nlyB-3gyxB:
undetectable		 3nlyA-3gyxB:
16.67
3nlyB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 3nlzA-3gyxA:
undetectable
3nlzB-3gyxA:
undetectable		 3nlzA-3gyxA:
20.98
3nlzB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 3nm0A-3gyxA:
2.5
3nm0B-3gyxA:
undetectable		 3nm0A-3gyxA:
20.98
3nm0B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.30A 3nm0A-3gyxB:
undetectable
3nm0B-3gyxB:
undetectable		 3nm0A-3gyxB:
16.67
3nm0B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.33A 3nnyA-3gyxA:
undetectable
3nnyB-3gyxA:
0.0		 3nnyA-3gyxA:
20.98
3nnyB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.27A 3nnyA-3gyxB:
undetectable
3nnyB-3gyxB:
undetectable		 3nnyA-3gyxB:
16.67
3nnyB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 3nnzA-3gyxA:
undetectable
3nnzB-3gyxA:
undetectable		 3nnzA-3gyxA:
20.98
3nnzB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 3nnzA-3gyxB:
undetectable
3nnzB-3gyxB:
undetectable		 3nnzA-3gyxB:
16.67
3nnzB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_A_PQNA847_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		5 / 9 SER A 242
GLY A 246
ALA B  71
LEU A 392
GLY A 286
 None
 1.17A 3pcqA-3gyxA:
0.2		 3pcqA-3gyxA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.33A 3pneA-3gyxA:
2.6
3pneB-3gyxA:
undetectable		 3pneA-3gyxA:
20.98
3pneB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.27A 3pneA-3gyxB:
undetectable
3pneB-3gyxB:
undetectable		 3pneA-3gyxB:
16.67
3pneB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 3pnfA-3gyxA:
undetectable
3pnfB-3gyxA:
undetectable		 3pnfA-3gyxA:
20.98
3pnfB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.30A 3pnfA-3gyxB:
undetectable
3pnfB-3gyxB:
undetectable		 3pnfA-3gyxB:
16.67
3pnfB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.34A 3pngA-3gyxA:
undetectable
3pngB-3gyxA:
undetectable		 3pngA-3gyxA:
20.98
3pngB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 3pngA-3gyxB:
undetectable
3pngB-3gyxB:
undetectable		 3pngA-3gyxB:
16.67
3pngB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 3q99A-3gyxA:
undetectable
3q99B-3gyxA:
undetectable		 3q99A-3gyxA:
20.98
3q99B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.32A 3q9aA-3gyxB:
undetectable
3q9aB-3gyxB:
undetectable		 3q9aA-3gyxB:
16.67
3q9aB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.34A 3rqjA-3gyxA:
undetectable
3rqjB-3gyxA:
undetectable		 3rqjA-3gyxA:
20.98
3rqjB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.30A 3rqjA-3gyxB:
undetectable
3rqjB-3gyxB:
undetectable		 3rqjA-3gyxB:
16.67
3rqjB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.33A 3rqlA-3gyxA:
2.5
3rqlB-3gyxA:
undetectable		 3rqlA-3gyxA:
20.98
3rqlB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 8 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 3rqlA-3gyxB:
undetectable
3rqlB-3gyxB:
undetectable		 3rqlA-3gyxB:
16.67
3rqlB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.34A 3rqmA-3gyxA:
undetectable
3rqmB-3gyxA:
undetectable		 3rqmA-3gyxA:
20.98
3rqmB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.30A 3rqmA-3gyxB:
undetectable
3rqmB-3gyxB:
undetectable		 3rqmA-3gyxB:
16.67
3rqmB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.33A 3rqnA-3gyxA:
2.5
3rqnB-3gyxA:
undetectable		 3rqnA-3gyxA:
20.98
3rqnB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 3rqnA-3gyxB:
undetectable
3rqnB-3gyxB:
undetectable		 3rqnA-3gyxB:
16.67
3rqnB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 3svpA-3gyxA:
undetectable
3svpB-3gyxA:
undetectable		 3svpA-3gyxA:
20.98
3svpB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.25A 3svpA-3gyxB:
undetectable
3svpB-3gyxB:
undetectable		 3svpA-3gyxB:
16.67
3svpB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 3tylA-3gyxA:
undetectable
3tylB-3gyxA:
undetectable		 3tylA-3gyxA:
20.98
3tylB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 3tylA-3gyxB:
undetectable
3tylB-3gyxB:
undetectable		 3tylA-3gyxB:
16.67
3tylB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.28A 3tymA-3gyxA:
undetectable
3tymB-3gyxA:
undetectable		 3tymA-3gyxA:
20.98
3tymB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 3tynA-3gyxA:
undetectable
3tynB-3gyxA:
undetectable		 3tynA-3gyxA:
20.98
3tynB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.26A 3tynA-3gyxB:
undetectable
3tynB-3gyxB:
undetectable		 3tynA-3gyxB:
16.67
3tynB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 3tyoA-3gyxA:
0.0
3tyoB-3gyxA:
undetectable		 3tyoA-3gyxA:
20.98
3tyoB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 3tyoA-3gyxB:
undetectable
3tyoB-3gyxB:
undetectable		 3tyoA-3gyxB:
16.67
3tyoB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.29A 3ufoA-3gyxA:
undetectable
3ufoB-3gyxA:
undetectable		 3ufoA-3gyxA:
20.98
3ufoB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 3ufoA-3gyxB:
undetectable
3ufoB-3gyxB:
undetectable		 3ufoA-3gyxB:
16.67
3ufoB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.29A 3ufpA-3gyxA:
undetectable
3ufpB-3gyxA:
2.7		 3ufpA-3gyxA:
20.98
3ufpB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.24A 3ufpA-3gyxB:
undetectable
3ufpB-3gyxB:
undetectable		 3ufpA-3gyxB:
16.67
3ufpB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.27A 3ufqA-3gyxA:
undetectable
3ufqB-3gyxA:
0.0		 3ufqA-3gyxA:
20.98
3ufqB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.25A 3ufqA-3gyxB:
undetectable
3ufqB-3gyxB:
undetectable		 3ufqA-3gyxB:
16.67
3ufqB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.43A 3ufrA-3gyxA:
undetectable
3ufrB-3gyxA:
0.0		 3ufrA-3gyxA:
20.98
3ufrB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.24A 3ufrA-3gyxB:
undetectable
3ufrB-3gyxB:
undetectable		 3ufrA-3gyxB:
16.67
3ufrB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 3ufsA-3gyxA:
undetectable
3ufsB-3gyxA:
undetectable		 3ufsA-3gyxA:
20.98
3ufsB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.26A 3ufsA-3gyxB:
undetectable
3ufsB-3gyxB:
undetectable		 3ufsA-3gyxB:
16.67
3ufsB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.26A 3uftA-3gyxB:
undetectable
3uftB-3gyxB:
undetectable		 3uftA-3gyxB:
16.67
3uftB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.33A 3ufuA-3gyxA:
undetectable
3ufuB-3gyxA:
undetectable		 3ufuA-3gyxA:
20.98
3ufuB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 3ufuA-3gyxB:
undetectable
3ufuB-3gyxB:
undetectable		 3ufuA-3gyxB:
16.67
3ufuB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.29A 3ufvA-3gyxA:
undetectable
3ufvB-3gyxA:
undetectable		 3ufvA-3gyxA:
20.98
3ufvB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.34A 3ufwA-3gyxA:
0.0
3ufwB-3gyxA:
undetectable		 3ufwA-3gyxA:
20.98
3ufwB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 3ufwA-3gyxB:
undetectable
3ufwB-3gyxB:
undetectable		 3ufwA-3gyxB:
16.67
3ufwB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		5 / 12 PRO A  18
LEU A 507
ILE A 511
ILE A  20
PHE A 500
 None
 1.29A 4a79B-3gyxA:
7.7		 4a79B-3gyxA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 4c39A-3gyxA:
0.0
4c39B-3gyxA:
undetectable		 4c39A-3gyxA:
20.98
4c39B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 4c39A-3gyxB:
undetectable
4c39B-3gyxB:
undetectable		 4c39A-3gyxB:
16.67
4c39B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.33A 4camA-3gyxA:
undetectable
4camB-3gyxA:
0.0		 4camA-3gyxA:
20.98
4camB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 4camA-3gyxB:
undetectable
4camB-3gyxB:
undetectable		 4camA-3gyxB:
16.67
4camB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.29A 4canA-3gyxA:
undetectable
4canB-3gyxA:
undetectable		 4canA-3gyxA:
20.98
4canB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 4canA-3gyxB:
undetectable
4canB-3gyxB:
undetectable		 4canA-3gyxB:
16.67
4canB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.28A 4caoA-3gyxA:
undetectable
4caoB-3gyxA:
0.0		 4caoA-3gyxA:
20.98
4caoB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.24A 4caoA-3gyxB:
undetectable
4caoB-3gyxB:
undetectable		 4caoA-3gyxB:
16.67
4caoB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.29A 4capA-3gyxA:
undetectable
4capB-3gyxA:
undetectable		 4capA-3gyxA:
20.98
4capB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 4caqA-3gyxA:
undetectable
4caqB-3gyxA:
0.0		 4caqA-3gyxA:
20.98
4caqB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 4caqA-3gyxB:
undetectable
4caqB-3gyxB:
undetectable		 4caqA-3gyxB:
16.67
4caqB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.29A 4cdtA-3gyxA:
undetectable
4cdtB-3gyxA:
undetectable		 4cdtA-3gyxA:
20.98
4cdtB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.27A 4cdtA-3gyxB:
undetectable
4cdtB-3gyxB:
undetectable		 4cdtA-3gyxB:
16.67
4cdtB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 4ctpA-3gyxA:
0.0
4ctpB-3gyxA:
undetectable		 4ctpA-3gyxA:
20.98
4ctpB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 4ctpA-3gyxB:
undetectable
4ctpB-3gyxB:
undetectable		 4ctpA-3gyxB:
16.67
4ctpB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 4ctqA-3gyxA:
0.0
4ctqB-3gyxA:
undetectable		 4ctqA-3gyxA:
20.98
4ctqB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.26A 4ctqA-3gyxB:
undetectable
4ctqB-3gyxB:
undetectable		 4ctqA-3gyxB:
16.67
4ctqB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 4ctrA-3gyxA:
undetectable
4ctrB-3gyxA:
undetectable		 4ctrA-3gyxA:
20.98
4ctrB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 4ctrA-3gyxB:
undetectable
4ctrB-3gyxB:
undetectable		 4ctrA-3gyxB:
16.67
4ctrB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 4cttA-3gyxA:
undetectable
4cttB-3gyxA:
undetectable		 4cttA-3gyxA:
20.98
4cttB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 4cttA-3gyxB:
undetectable
4cttB-3gyxB:
undetectable		 4cttA-3gyxB:
16.67
4cttB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 4ctuA-3gyxA:
undetectable
4ctuB-3gyxA:
0.0		 4ctuA-3gyxA:
20.98
4ctuB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.33A 4ctvA-3gyxA:
undetectable
4ctvB-3gyxA:
undetectable		 4ctvA-3gyxA:
20.98
4ctvB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.32A 4ctvA-3gyxB:
undetectable
4ctvB-3gyxB:
undetectable		 4ctvA-3gyxB:
16.67
4ctvB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.33A 4ctwA-3gyxA:
0.0
4ctwB-3gyxA:
undetectable		 4ctwA-3gyxA:
20.98
4ctwB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.33A 4ctwA-3gyxB:
undetectable
4ctwB-3gyxB:
undetectable		 4ctwA-3gyxB:
16.67
4ctwB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.35A 4ctxA-3gyxA:
0.0
4ctxB-3gyxA:
undetectable		 4ctxA-3gyxA:
20.98
4ctxB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.32A 4ctxA-3gyxB:
undetectable
4ctxB-3gyxB:
undetectable		 4ctxA-3gyxB:
16.67
4ctxB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.34A 4cx5A-3gyxA:
undetectable
4cx5B-3gyxA:
undetectable		 4cx5A-3gyxA:
20.98
4cx5B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.32A 4cx5A-3gyxB:
undetectable
4cx5B-3gyxB:
undetectable		 4cx5A-3gyxB:
16.92
4cx5B-3gyxB:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.33A 4cx6A-3gyxA:
undetectable
4cx6B-3gyxA:
undetectable		 4cx6A-3gyxA:
20.98
4cx6B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 4cx6A-3gyxB:
undetectable
4cx6B-3gyxB:
undetectable		 4cx6A-3gyxB:
16.92
4cx6B-3gyxB:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.35A 4d1nA-3gyxA:
undetectable
4d1nB-3gyxA:
undetectable		 4d1nA-3gyxA:
21.00
4d1nB-3gyxA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.34A 4d1nA-3gyxB:
undetectable
4d1nB-3gyxB:
undetectable		 4d1nA-3gyxB:
17.91
4d1nB-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 4d1nC-3gyxA:
undetectable
4d1nD-3gyxA:
undetectable		 4d1nC-3gyxA:
21.00
4d1nD-3gyxA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 4d1nC-3gyxB:
undetectable
4d1nD-3gyxB:
undetectable		 4d1nC-3gyxB:
17.91
4d1nD-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.28A 4d2yA-3gyxA:
undetectable
4d2yB-3gyxA:
undetectable		 4d2yA-3gyxA:
20.98
4d2yB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.27A 4d2yA-3gyxB:
undetectable
4d2yB-3gyxB:
undetectable		 4d2yA-3gyxB:
16.67
4d2yB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.23A 4d2zA-3gyxA:
undetectable
4d2zB-3gyxA:
undetectable		 4d2zA-3gyxA:
20.98
4d2zB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.26A 4d2zA-3gyxB:
undetectable
4d2zB-3gyxB:
undetectable		 4d2zA-3gyxB:
16.67
4d2zB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.26A 4d30A-3gyxB:
undetectable
4d30B-3gyxB:
undetectable		 4d30A-3gyxB:
16.67
4d30B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.27A 4d31A-3gyxA:
undetectable
4d31B-3gyxA:
undetectable		 4d31A-3gyxA:
20.98
4d31B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 4d32A-3gyxA:
undetectable
4d32B-3gyxA:
undetectable		 4d32A-3gyxA:
20.98
4d32B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.33A 4d3bA-3gyxA:
2.6
4d3bB-3gyxA:
undetectable		 4d3bA-3gyxA:
20.98
4d3bB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.30A 4d3bA-3gyxB:
undetectable
4d3bB-3gyxB:
undetectable		 4d3bA-3gyxB:
16.67
4d3bB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 4d7oA-3gyxA:
undetectable
4d7oB-3gyxA:
2.5		 4d7oA-3gyxA:
20.98
4d7oB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_D_SAMD800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		5 / 10 ILE A  20
ALA A 504
GLU A 506
GLY A 208
HIS A 220
 None
 1.37A 4e47D-3gyxA:
undetectable		 4e47D-3gyxA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.34A 4euxA-3gyxA:
undetectable
4euxB-3gyxA:
2.5		 4euxA-3gyxA:
20.98
4euxB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		3 / 3 PHE A 278
TYR A 287
TYR A 413
 None
 0.93A 4ffwA-3gyxA:
undetectable		 4ffwA-3gyxA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_2
(DIPEPTIDYL PEPTIDASE
4)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		3 / 3 ARG A 336
TYR A 413
ASN A 276
 None
 0.79A 4ffwB-3gyxA:
undetectable		 4ffwB-3gyxA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.33A 4fvwA-3gyxA:
undetectable
4fvwB-3gyxA:
undetectable		 4fvwA-3gyxA:
20.98
4fvwB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.32A 4fvwA-3gyxB:
undetectable
4fvwB-3gyxB:
undetectable		 4fvwA-3gyxB:
16.67
4fvwB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 4fvxA-3gyxA:
undetectable
4fvxB-3gyxA:
undetectable		 4fvxA-3gyxA:
20.98
4fvxB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 4fvxA-3gyxB:
undetectable
4fvxB-3gyxB:
undetectable		 4fvxA-3gyxB:
16.67
4fvxB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 4fvyA-3gyxA:
undetectable
4fvyB-3gyxA:
undetectable		 4fvyA-3gyxA:
20.98
4fvyB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.30A 4fvzA-3gyxB:
undetectable
4fvzB-3gyxB:
undetectable		 4fvzA-3gyxB:
16.67
4fvzB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.33A 4fw0A-3gyxA:
undetectable
4fw0B-3gyxA:
undetectable		 4fw0A-3gyxA:
20.98
4fw0B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 4fw0A-3gyxB:
undetectable
4fw0B-3gyxB:
undetectable		 4fw0A-3gyxB:
16.67
4fw0B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 4gqeA-3gyxA:
undetectable
4gqeB-3gyxA:
undetectable		 4gqeA-3gyxA:
20.98
4gqeB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.30A 4gqeA-3gyxB:
undetectable
4gqeB-3gyxB:
undetectable		 4gqeA-3gyxB:
16.67
4gqeB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_D_SAMD401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		5 / 11 ILE A  20
ALA A 504
GLU A 506
GLY A 208
HIS A 220
 None
 1.38A 4jdsD-3gyxA:
undetectable		 4jdsD-3gyxA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.34A 4jsfA-3gyxA:
0.0
4jsfB-3gyxA:
undetectable		 4jsfA-3gyxA:
20.98
4jsfB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 4jsgA-3gyxA:
undetectable
4jsgB-3gyxA:
undetectable		 4jsgA-3gyxA:
20.44
4jsgB-3gyxA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.30A 4jsgA-3gyxB:
undetectable
4jsgB-3gyxB:
undetectable		 4jsgA-3gyxB:
16.67
4jsgB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.26A 4jshA-3gyxB:
undetectable
4jshB-3gyxB:
undetectable		 4jshA-3gyxB:
16.67
4jshB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 4jsiA-3gyxA:
undetectable
4jsiB-3gyxA:
undetectable		 4jsiA-3gyxA:
20.98
4jsiB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.25A 4jsiA-3gyxB:
undetectable
4jsiB-3gyxB:
undetectable		 4jsiA-3gyxB:
16.67
4jsiB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 4jsjA-3gyxA:
undetectable
4jsjB-3gyxA:
undetectable		 4jsjA-3gyxA:
20.98
4jsjB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 4jsjA-3gyxB:
undetectable
4jsjB-3gyxB:
undetectable		 4jsjA-3gyxB:
16.67
4jsjB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA505_0
(RNA POLYMERASE
3D-POL)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		3 / 3 CYH A 231
ASN A 256
LYS A  61
 FAD  A1000 (-3.5A)
FAD  A1000 ( 4.4A)
None
 1.45A 4k50A-3gyxA:
undetectable		 4k50A-3gyxA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 4k5dA-3gyxA:
undetectable
4k5dB-3gyxA:
undetectable		 4k5dA-3gyxA:
20.98
4k5dB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 4k5dA-3gyxB:
undetectable
4k5dB-3gyxB:
undetectable		 4k5dA-3gyxB:
16.67
4k5dB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 4k5eA-3gyxA:
undetectable
4k5eB-3gyxA:
undetectable		 4k5eA-3gyxA:
20.44
4k5eB-3gyxA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 4k5eA-3gyxB:
undetectable
4k5eB-3gyxB:
undetectable		 4k5eA-3gyxB:
16.67
4k5eB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 4k5fA-3gyxA:
undetectable
4k5fB-3gyxA:
undetectable		 4k5fA-3gyxA:
20.98
4k5fB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 4k5fA-3gyxB:
undetectable
4k5fB-3gyxB:
undetectable		 4k5fA-3gyxB:
16.67
4k5fB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.33A 4k5gA-3gyxA:
undetectable
4k5gB-3gyxA:
undetectable		 4k5gA-3gyxA:
20.98
4k5gB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.30A 4k5gA-3gyxB:
undetectable
4k5gB-3gyxB:
undetectable		 4k5gA-3gyxB:
16.67
4k5gB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.28A 4kchA-3gyxA:
undetectable
4kchB-3gyxA:
undetectable		 4kchA-3gyxA:
20.98
4kchB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 4kciA-3gyxA:
undetectable
4kciB-3gyxA:
undetectable		 4kciA-3gyxA:
20.98
4kciB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.27A 4kciA-3gyxB:
undetectable
4kciB-3gyxB:
undetectable		 4kciA-3gyxB:
16.67
4kciB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 4kcjA-3gyxA:
undetectable
4kcjB-3gyxA:
undetectable		 4kcjA-3gyxA:
20.98
4kcjB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.30A 4kcjA-3gyxB:
undetectable
4kcjB-3gyxB:
undetectable		 4kcjA-3gyxB:
16.67
4kcjB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.25A 4kckA-3gyxA:
undetectable
4kckB-3gyxA:
undetectable		 4kckA-3gyxA:
20.98
4kckB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.26A 4kckA-3gyxB:
undetectable
4kckB-3gyxB:
undetectable		 4kckA-3gyxB:
16.67
4kckB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.29A 4kclA-3gyxA:
undetectable
4kclB-3gyxA:
2.7		 4kclA-3gyxA:
20.98
4kclB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 4kclA-3gyxB:
undetectable
4kclB-3gyxB:
undetectable		 4kclA-3gyxB:
16.67
4kclB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.26A 4kcmA-3gyxA:
undetectable
4kcmB-3gyxA:
undetectable		 4kcmA-3gyxA:
20.98
4kcmB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 4kcnA-3gyxA:
undetectable
4kcnB-3gyxA:
0.0		 4kcnA-3gyxA:
20.98
4kcnB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 4kcnA-3gyxB:
undetectable
4kcnB-3gyxB:
undetectable		 4kcnA-3gyxB:
16.67
4kcnB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.29A 4kcoA-3gyxA:
0.0
4kcoB-3gyxA:
undetectable		 4kcoA-3gyxA:
20.98
4kcoB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 4kcoA-3gyxB:
undetectable
4kcoB-3gyxB:
undetectable		 4kcoA-3gyxB:
16.67
4kcoB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_A_LYAA304_1
(FOLATE RECEPTOR BETA)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		5 / 12 ASP A  96
THR A 333
TRP A 251
HIS A 418
GLY A 233
 None
None
FAD  A1000 (-3.7A)
FAD  A1000 (-4.5A)
None
 1.40A 4kn2A-3gyxA:
undetectable		 4kn2A-3gyxA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_B_LYAB304_1
(FOLATE RECEPTOR BETA)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		5 / 12 ASP A  96
THR A 333
TRP A 251
HIS A 418
GLY A 233
 None
None
FAD  A1000 (-3.7A)
FAD  A1000 (-4.5A)
None
 1.40A 4kn2B-3gyxA:
0.0		 4kn2B-3gyxA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_1
(FOLATE RECEPTOR BETA)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		5 / 12 ASP A  96
THR A 333
TRP A 251
HIS A 418
GLY A 233
 None
None
FAD  A1000 (-3.7A)
FAD  A1000 (-4.5A)
None
 1.40A 4kn2C-3gyxA:
undetectable		 4kn2C-3gyxA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		5 / 11 SER A 242
GLY A 246
ALA B  71
LEU A 392
GLY A 286
 None
 1.18A 4l6v1-3gyxA:
undetectable
4l6v6-3gyxA:
undetectable		 4l6v1-3gyxA:
21.07
4l6v6-3gyxA:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 4luxA-3gyxA:
0.0
4luxB-3gyxA:
undetectable		 4luxA-3gyxA:
20.98
4luxB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 4luxA-3gyxB:
undetectable
4luxB-3gyxB:
undetectable		 4luxA-3gyxB:
16.67
4luxB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NED_A_PFNA709_1
(LACTOTRANSFERRIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 VAL A 434
ASP A 104
ALA A 466
PHE A 639
 None
 1.22A 4nedA-3gyxA:
undetectable		 4nedA-3gyxA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		3 / 3 GLU A 505
TYR A 516
GLU A  17
 None
 0.74A 4ryaA-3gyxA:
undetectable		 4ryaA-3gyxA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 4 ALA A 142
VAL A 127
GLY A 124
THR B 106
 None
 0.78A 4ubeA-3gyxA:
2.9		 4ubeA-3gyxA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.28A 4uchA-3gyxA:
0.0
4uchB-3gyxA:
undetectable		 4uchA-3gyxA:
20.83
4uchB-3gyxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.34A 4ugzA-3gyxA:
undetectable
4ugzB-3gyxA:
undetectable		 4ugzA-3gyxA:
20.98
4ugzB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.27A 4ugzA-3gyxB:
undetectable
4ugzB-3gyxB:
undetectable		 4ugzA-3gyxB:
16.67
4ugzB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 4uh0A-3gyxA:
undetectable
4uh0B-3gyxA:
undetectable		 4uh0A-3gyxA:
20.98
4uh0B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.27A 4uh0A-3gyxB:
undetectable
4uh0B-3gyxB:
undetectable		 4uh0A-3gyxB:
16.67
4uh0B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 4uh1A-3gyxA:
undetectable
4uh1B-3gyxA:
undetectable		 4uh1A-3gyxA:
20.98
4uh1B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 4uh1A-3gyxB:
undetectable
4uh1B-3gyxB:
undetectable		 4uh1A-3gyxB:
16.67
4uh1B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.33A 4uh2A-3gyxA:
undetectable
4uh2B-3gyxA:
undetectable		 4uh2A-3gyxA:
20.98
4uh2B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.27A 4uh2A-3gyxB:
undetectable
4uh2B-3gyxB:
undetectable		 4uh2A-3gyxB:
16.67
4uh2B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.33A 4uh3A-3gyxA:
undetectable
4uh3B-3gyxA:
0.0		 4uh3A-3gyxA:
20.98
4uh3B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 4uh4A-3gyxA:
undetectable
4uh4B-3gyxA:
undetectable		 4uh4A-3gyxA:
20.98
4uh4B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.26A 4uh4A-3gyxB:
undetectable
4uh4B-3gyxB:
undetectable		 4uh4A-3gyxB:
16.67
4uh4B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 4uh5A-3gyxA:
undetectable
4uh5B-3gyxA:
undetectable		 4uh5A-3gyxA:
20.86
4uh5B-3gyxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 4uh5A-3gyxB:
undetectable
4uh5B-3gyxB:
undetectable		 4uh5A-3gyxB:
17.91
4uh5B-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.34A 4uh6A-3gyxA:
0.0
4uh6B-3gyxA:
2.5		 4uh6A-3gyxA:
20.86
4uh6B-3gyxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 4uh6A-3gyxB:
undetectable
4uh6B-3gyxB:
undetectable		 4uh6A-3gyxB:
17.91
4uh6B-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 4upmA-3gyxA:
undetectable
4upmB-3gyxA:
0.0		 4upmA-3gyxA:
20.98
4upmB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.27A 4upmA-3gyxB:
undetectable
4upmB-3gyxB:
undetectable		 4upmA-3gyxB:
16.67
4upmB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.27A 4upnA-3gyxA:
undetectable
4upnB-3gyxA:
2.7		 4upnA-3gyxA:
20.98
4upnB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.24A 4upnA-3gyxB:
undetectable
4upnB-3gyxB:
undetectable		 4upnA-3gyxB:
16.67
4upnB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 4upoA-3gyxA:
undetectable
4upoB-3gyxA:
undetectable		 4upoA-3gyxA:
20.98
4upoB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.27A 4upoA-3gyxB:
undetectable
4upoB-3gyxB:
undetectable		 4upoA-3gyxB:
16.67
4upoB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.29A 4uppA-3gyxA:
undetectable
4uppB-3gyxA:
undetectable		 4uppA-3gyxA:
20.98
4uppB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 4uppA-3gyxB:
undetectable
4uppB-3gyxB:
undetectable		 4uppA-3gyxB:
16.67
4uppB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.24A 4v3uA-3gyxA:
0.0
4v3uB-3gyxA:
undetectable		 4v3uA-3gyxA:
21.00
4v3uB-3gyxA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.30A 4v3uA-3gyxB:
undetectable
4v3uB-3gyxB:
undetectable		 4v3uA-3gyxB:
17.91
4v3uB-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.28A 4v3uC-3gyxA:
2.4
4v3uD-3gyxA:
undetectable		 4v3uC-3gyxA:
21.00
4v3uD-3gyxA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.26A 4v3vA-3gyxA:
0.0
4v3vB-3gyxA:
undetectable		 4v3vA-3gyxA:
20.98
4v3vB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.25A 4v3vA-3gyxB:
undetectable
4v3vB-3gyxB:
undetectable		 4v3vA-3gyxB:
16.67
4v3vB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.27A 4v3yA-3gyxA:
undetectable
4v3yB-3gyxA:
undetectable		 4v3yA-3gyxA:
20.98
4v3yB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA907_0
(PROTEIN ARGONAUTE-2)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 5 ALA A 257
THR A 603
THR A 262
TYR A 261
 None
 1.15A 4w5oA-3gyxA:
0.6		 4w5oA-3gyxA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ALA A 257
THR A 603
THR A 262
TYR A 261
 None
 1.11A 4w5qA-3gyxA:
undetectable		 4w5qA-3gyxA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		5 / 12 GLY A 416
TYR A  89
LEU A 109
PHE A 471
LEU A  97
 None
 1.30A 4xldA-3gyxA:
undetectable		 4xldA-3gyxA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA907_0
(PROTEIN ARGONAUTE-2)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 5 ALA A 257
THR A 603
THR A 262
TYR A 261
 None
 1.15A 4z4eA-3gyxA:
0.6		 4z4eA-3gyxA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ALA A 257
THR A 603
THR A 262
TYR A 261
 None
 1.14A 4z4fA-3gyxA:
undetectable		 4z4fA-3gyxA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 5 ALA A 257
THR A 603
THR A 262
TYR A 261
 None
 1.14A 4z4gA-3gyxA:
undetectable		 4z4gA-3gyxA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ALA A 257
THR A 603
THR A 262
TYR A 261
 None
 1.12A 4z4iA-3gyxA:
undetectable		 4z4iA-3gyxA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 5ad4A-3gyxA:
undetectable
5ad4B-3gyxA:
undetectable		 5ad4A-3gyxA:
20.98
5ad4B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.27A 5ad4A-3gyxB:
undetectable
5ad4B-3gyxB:
undetectable		 5ad4A-3gyxB:
16.67
5ad4B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 5ad5A-3gyxA:
undetectable
5ad5B-3gyxA:
undetectable		 5ad5A-3gyxA:
20.98
5ad5B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.27A 5ad5A-3gyxB:
undetectable
5ad5B-3gyxB:
undetectable		 5ad5A-3gyxB:
16.67
5ad5B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.26A 5ad6A-3gyxA:
0.0
5ad6B-3gyxA:
undetectable		 5ad6A-3gyxA:
20.98
5ad6B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.26A 5ad6A-3gyxB:
undetectable
5ad6B-3gyxB:
undetectable		 5ad6A-3gyxB:
16.67
5ad6B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 5ad7A-3gyxB:
undetectable
5ad7B-3gyxB:
undetectable		 5ad7A-3gyxB:
16.67
5ad7B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 5ad8A-3gyxB:
undetectable
5ad8B-3gyxB:
undetectable		 5ad8A-3gyxB:
16.67
5ad8B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.27A 5ad9A-3gyxA:
undetectable
5ad9B-3gyxA:
undetectable		 5ad9A-3gyxA:
20.98
5ad9B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.22A 5ad9A-3gyxB:
undetectable
5ad9B-3gyxB:
undetectable		 5ad9A-3gyxB:
16.67
5ad9B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 5adaA-3gyxA:
undetectable
5adaB-3gyxA:
undetectable		 5adaA-3gyxA:
20.98
5adaB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.25A 5adaA-3gyxB:
undetectable
5adaB-3gyxB:
undetectable		 5adaA-3gyxB:
16.67
5adaB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.27A 5adbA-3gyxB:
undetectable
5adbB-3gyxB:
undetectable		 5adbA-3gyxB:
16.67
5adbB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 5adcA-3gyxA:
undetectable
5adcB-3gyxA:
undetectable		 5adcA-3gyxA:
20.98
5adcB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 5adcA-3gyxB:
undetectable
5adcB-3gyxB:
undetectable		 5adcA-3gyxB:
16.67
5adcB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 5addA-3gyxB:
undetectable
5addB-3gyxB:
undetectable		 5addA-3gyxB:
19.15
5addB-3gyxB:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.21A 5adeA-3gyxB:
undetectable
5adeB-3gyxB:
undetectable		 5adeA-3gyxB:
19.15
5adeB-3gyxB:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 5adfA-3gyxA:
0.0
5adfB-3gyxA:
2.7		 5adfA-3gyxA:
20.86
5adfB-3gyxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.28A 5adgA-3gyxA:
undetectable
5adgB-3gyxA:
undetectable		 5adgA-3gyxA:
20.86
5adgB-3gyxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.30A 5adgA-3gyxB:
undetectable
5adgB-3gyxB:
undetectable		 5adgA-3gyxB:
17.91
5adgB-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.28A 5adiA-3gyxA:
undetectable
5adiB-3gyxA:
2.8		 5adiA-3gyxA:
20.86
5adiB-3gyxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.28A 5agkA-3gyxA:
undetectable
5agkB-3gyxA:
2.7		 5agkA-3gyxA:
20.98
5agkB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.32A 5agkA-3gyxB:
undetectable
5agkB-3gyxB:
undetectable		 5agkA-3gyxB:
16.67
5agkB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 5aglA-3gyxA:
undetectable
5aglB-3gyxA:
undetectable		 5aglA-3gyxA:
20.98
5aglB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 5aglA-3gyxB:
undetectable
5aglB-3gyxB:
undetectable		 5aglA-3gyxB:
16.67
5aglB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 5agmA-3gyxA:
undetectable
5agmB-3gyxA:
undetectable		 5agmA-3gyxA:
20.98
5agmB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 5agnA-3gyxA:
undetectable
5agnB-3gyxA:
undetectable		 5agnA-3gyxA:
20.98
5agnB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 5agnA-3gyxB:
undetectable
5agnB-3gyxB:
undetectable		 5agnA-3gyxB:
16.67
5agnB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 5agoA-3gyxA:
undetectable
5agoB-3gyxA:
undetectable		 5agoA-3gyxA:
20.98
5agoB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 5agoA-3gyxB:
undetectable
5agoB-3gyxB:
undetectable		 5agoA-3gyxB:
16.67
5agoB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 3gyx ADENYLYLSULFATE
REDUCTASE
ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas;
Desulfovibrio
gigas) 		3 / 3 THR B 133
ASP A 115
GLU A  42
 None
 0.85A 5fa8A-3gyxB:
undetectable		 5fa8A-3gyxB:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.26A 5fvpA-3gyxA:
2.6
5fvpB-3gyxA:
undetectable		 5fvpA-3gyxA:
20.98
5fvpB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.26A 5fvpA-3gyxB:
undetectable
5fvpB-3gyxB:
undetectable		 5fvpA-3gyxB:
16.67
5fvpB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 5fvqA-3gyxB:
undetectable
5fvqB-3gyxB:
undetectable		 5fvqA-3gyxB:
16.67
5fvqB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.35A 5fvrA-3gyxA:
undetectable
5fvrB-3gyxA:
undetectable		 5fvrA-3gyxA:
20.98
5fvrB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.30A 5fvrA-3gyxB:
undetectable
5fvrB-3gyxB:
undetectable		 5fvrA-3gyxB:
16.67
5fvrB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 5fvsA-3gyxB:
undetectable
5fvsB-3gyxB:
undetectable		 5fvsA-3gyxB:
16.67
5fvsB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.32A 5fvtA-3gyxB:
undetectable
5fvtB-3gyxB:
undetectable		 5fvtA-3gyxB:
16.67
5fvtB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 5fvuA-3gyxB:
undetectable
5fvuB-3gyxB:
undetectable		 5fvuA-3gyxB:
17.91
5fvuB-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.34A 5fvvA-3gyxA:
0.0
5fvvB-3gyxA:
undetectable		 5fvvA-3gyxA:
20.86
5fvvB-3gyxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.27A 5fvwA-3gyxA:
undetectable
5fvwB-3gyxA:
undetectable		 5fvwA-3gyxA:
20.86
5fvwB-3gyxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.33A 5fvwA-3gyxB:
undetectable
5fvwB-3gyxB:
undetectable		 5fvwA-3gyxB:
17.91
5fvwB-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.29A 5fvxA-3gyxA:
undetectable
5fvxB-3gyxA:
2.2		 5fvxA-3gyxA:
20.86
5fvxB-3gyxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 5fw0A-3gyxA:
undetectable
5fw0B-3gyxA:
undetectable		 5fw0A-3gyxA:
20.98
5fw0B-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.27A 5fw0A-3gyxB:
undetectable
5fw0B-3gyxB:
undetectable		 5fw0A-3gyxB:
16.67
5fw0B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 5g0nA-3gyxB:
undetectable
5g0nB-3gyxB:
undetectable		 5g0nA-3gyxB:
16.67
5g0nB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 5g0oA-3gyxA:
undetectable
5g0oB-3gyxA:
undetectable		 5g0oA-3gyxA:
20.30
5g0oB-3gyxA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.27A 5g0oA-3gyxB:
undetectable
5g0oB-3gyxB:
undetectable		 5g0oA-3gyxB:
16.67
5g0oB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.29A 5g0pA-3gyxA:
undetectable
5g0pB-3gyxA:
undetectable		 5g0pA-3gyxA:
20.30
5g0pB-3gyxA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		5 / 11 PRO A 514
LEU A 591
VAL A 219
VAL A 194
GLY A 211
 None
 1.39A 5hbmA-3gyxA:
undetectable		 5hbmA-3gyxA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_E_SAME301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		5 / 12 ALA A 626
PRO A 412
GLY A 553
THR A 548
TYR A 559
 None
 1.20A 5hfjE-3gyxA:
undetectable		 5hfjE-3gyxA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		5 / 9 SER A 242
GLY A 246
ALA B  71
LEU A 392
GLY A 286
 None
 1.18A 5l8rA-3gyxA:
undetectable		 5l8rA-3gyxA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 5unrA-3gyxB:
undetectable
5unrB-3gyxB:
undetectable		 5unrA-3gyxB:
16.67
5unrB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.34A 5unsA-3gyxA:
undetectable
5unsB-3gyxA:
undetectable		 5unsA-3gyxA:
20.98
5unsB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 5unsA-3gyxB:
undetectable
5unsB-3gyxB:
undetectable		 5unsA-3gyxB:
16.67
5unsB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.33A 5untA-3gyxA:
undetectable
5untB-3gyxA:
undetectable		 5untA-3gyxA:
20.98
5untB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.30A 5untA-3gyxB:
undetectable
5untB-3gyxB:
undetectable		 5untA-3gyxB:
16.67
5untB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 5unuA-3gyxA:
undetectable
5unuB-3gyxA:
undetectable		 5unuA-3gyxA:
20.98
5unuB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.25A 5unuA-3gyxB:
undetectable
5unuB-3gyxB:
undetectable		 5unuA-3gyxB:
16.67
5unuB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 5unvA-3gyxB:
undetectable
5unvB-3gyxB:
undetectable		 5unvA-3gyxB:
16.67
5unvB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.29A 5unwA-3gyxA:
undetectable
5unwB-3gyxA:
undetectable		 5unwA-3gyxA:
20.98
5unwB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.25A 5unwA-3gyxB:
undetectable
5unwB-3gyxB:
undetectable		 5unwA-3gyxB:
16.67
5unwB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.23A 5unxA-3gyxA:
2.6
5unxB-3gyxA:
undetectable		 5unxA-3gyxA:
20.98
5unxB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.22A 5unxA-3gyxB:
undetectable
5unxB-3gyxB:
undetectable		 5unxA-3gyxB:
16.67
5unxB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.28A 5unyA-3gyxA:
undetectable
5unyB-3gyxA:
undetectable		 5unyA-3gyxA:
20.98
5unyB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 5unyA-3gyxB:
undetectable
5unyB-3gyxB:
undetectable		 5unyA-3gyxB:
16.67
5unyB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 5unzA-3gyxB:
undetectable
5unzB-3gyxB:
undetectable		 5unzA-3gyxB:
16.67
5unzB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.27A 5uo0A-3gyxB:
undetectable
5uo0B-3gyxB:
undetectable		 5uo0A-3gyxB:
16.67
5uo0B-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.28A 5uo1A-3gyxA:
undetectable
5uo1B-3gyxA:
undetectable		 5uo1A-3gyxA:
20.86
5uo1B-3gyxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 5uo1A-3gyxB:
undetectable
5uo1B-3gyxB:
undetectable		 5uo1A-3gyxB:
17.91
5uo1B-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.32A 5uo2A-3gyxB:
undetectable
5uo2B-3gyxB:
undetectable		 5uo2A-3gyxB:
17.91
5uo2B-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.24A 5uo3A-3gyxA:
undetectable
5uo3B-3gyxA:
undetectable		 5uo3A-3gyxA:
20.86
5uo3B-3gyxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 5uo3A-3gyxB:
undetectable
5uo3B-3gyxB:
undetectable		 5uo3A-3gyxB:
17.91
5uo3B-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 5uo4A-3gyxA:
undetectable
5uo4B-3gyxA:
undetectable		 5uo4A-3gyxA:
20.86
5uo4B-3gyxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.32A 5uo4A-3gyxB:
undetectable
5uo4B-3gyxB:
undetectable		 5uo4A-3gyxB:
17.91
5uo4B-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 5uo5A-3gyxA:
undetectable
5uo5B-3gyxA:
undetectable		 5uo5A-3gyxA:
20.86
5uo5B-3gyxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.32A 5uo5A-3gyxB:
undetectable
5uo5B-3gyxB:
undetectable		 5uo5A-3gyxB:
17.91
5uo5B-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 5uo6A-3gyxB:
undetectable
5uo6B-3gyxB:
undetectable		 5uo6A-3gyxB:
17.91
5uo6B-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.26A 5uo7A-3gyxB:
undetectable
5uo7B-3gyxB:
undetectable		 5uo7A-3gyxB:
17.91
5uo7B-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 4 LEU A  57
LEU A  28
SER A  24
ALA A 224
 None
 1.07A 5uunA-3gyxA:
undetectable		 5uunA-3gyxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.29A 5vuiA-3gyxA:
undetectable
5vuiB-3gyxA:
undetectable		 5vuiA-3gyxA:
20.98
5vuiB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.26A 5vuiA-3gyxB:
undetectable
5vuiB-3gyxB:
undetectable		 5vuiA-3gyxB:
16.67
5vuiB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.35A 5vujA-3gyxA:
undetectable
5vujB-3gyxA:
0.0		 5vujA-3gyxA:
20.98
5vujB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 5vujA-3gyxB:
undetectable
5vujB-3gyxB:
undetectable		 5vujA-3gyxB:
16.67
5vujB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.28A 5vukA-3gyxA:
undetectable
5vukB-3gyxA:
undetectable		 5vukA-3gyxA:
20.98
5vukB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 5vukA-3gyxB:
undetectable
5vukB-3gyxB:
undetectable		 5vukA-3gyxB:
16.67
5vukB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 5vulA-3gyxA:
undetectable
5vulB-3gyxA:
undetectable		 5vulA-3gyxA:
20.98
5vulB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 5vulA-3gyxB:
undetectable
5vulB-3gyxB:
undetectable		 5vulA-3gyxB:
16.67
5vulB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 5vumA-3gyxA:
undetectable
5vumB-3gyxA:
undetectable		 5vumA-3gyxA:
20.98
5vumB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 5vumA-3gyxB:
undetectable
5vumB-3gyxB:
undetectable		 5vumA-3gyxB:
16.67
5vumB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 5vunA-3gyxA:
undetectable
5vunB-3gyxA:
undetectable		 5vunA-3gyxA:
20.98
5vunB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 5vunA-3gyxB:
undetectable
5vunB-3gyxB:
undetectable		 5vunA-3gyxB:
16.67
5vunB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.33A 5vuoA-3gyxA:
2.7
5vuoB-3gyxA:
undetectable		 5vuoA-3gyxA:
20.98
5vuoB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 5vuoA-3gyxB:
undetectable
5vuoB-3gyxB:
undetectable		 5vuoA-3gyxB:
16.67
5vuoB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 5vupA-3gyxA:
undetectable
5vupB-3gyxA:
undetectable		 5vupA-3gyxA:
20.98
5vupB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 5vupA-3gyxB:
undetectable
5vupB-3gyxB:
undetectable		 5vupA-3gyxB:
16.67
5vupB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 5vuqA-3gyxA:
undetectable
5vuqB-3gyxA:
undetectable		 5vuqA-3gyxA:
20.98
5vuqB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 5vuqA-3gyxB:
undetectable
5vuqB-3gyxB:
undetectable		 5vuqA-3gyxB:
16.67
5vuqB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 5vurA-3gyxB:
undetectable
5vurB-3gyxB:
undetectable		 5vurA-3gyxB:
16.67
5vurB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 5vusA-3gyxA:
2.5
5vusB-3gyxA:
undetectable		 5vusA-3gyxA:
20.98
5vusB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.25A 5vusA-3gyxB:
undetectable
5vusB-3gyxB:
undetectable		 5vusA-3gyxB:
16.67
5vusB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.33A 5vutA-3gyxA:
undetectable
5vutB-3gyxA:
undetectable		 5vutA-3gyxA:
20.98
5vutB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.27A 5vutA-3gyxB:
undetectable
5vutB-3gyxB:
undetectable		 5vutA-3gyxB:
16.67
5vutB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 5vuuA-3gyxA:
undetectable
5vuuB-3gyxA:
undetectable		 5vuuA-3gyxA:
20.98
5vuuB-3gyxA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 5vuuA-3gyxB:
undetectable
5vuuB-3gyxB:
undetectable		 5vuuA-3gyxB:
16.67
5vuuB-3gyxB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 5vuvA-3gyxA:
2.6
5vuvB-3gyxA:
undetectable		 5vuvA-3gyxA:
20.86
5vuvB-3gyxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 5vuvA-3gyxB:
undetectable
5vuvB-3gyxB:
undetectable		 5vuvA-3gyxB:
17.91
5vuvB-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.27A 5vuwA-3gyxA:
undetectable
5vuwB-3gyxA:
undetectable		 5vuwA-3gyxA:
20.86
5vuwB-3gyxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.33A 5vuwA-3gyxB:
undetectable
5vuwB-3gyxB:
undetectable		 5vuwA-3gyxB:
17.91
5vuwB-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 5vuxA-3gyxA:
undetectable
5vuxB-3gyxA:
undetectable		 5vuxA-3gyxA:
20.86
5vuxB-3gyxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.24A 5vuyA-3gyxA:
2.6
5vuyB-3gyxA:
undetectable		 5vuyA-3gyxA:
20.86
5vuyB-3gyxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.30A 5vuyA-3gyxB:
undetectable
5vuyB-3gyxB:
undetectable		 5vuyA-3gyxB:
17.91
5vuyB-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 5vuzA-3gyxA:
undetectable
5vuzB-3gyxA:
undetectable		 5vuzA-3gyxA:
20.86
5vuzB-3gyxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.32A 5vuzA-3gyxB:
undetectable
5vuzB-3gyxB:
undetectable		 5vuzA-3gyxB:
17.91
5vuzB-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 5vv0A-3gyxA:
2.6
5vv0B-3gyxA:
2.8		 5vv0A-3gyxA:
21.01
5vv0B-3gyxA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.30A 5vv0A-3gyxB:
undetectable
5vv0B-3gyxB:
undetectable		 5vv0A-3gyxB:
17.91
5vv0B-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 5vv1A-3gyxA:
undetectable
5vv1B-3gyxA:
2.9		 5vv1A-3gyxA:
20.86
5vv1B-3gyxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.32A 5vv1A-3gyxB:
undetectable
5vv1B-3gyxB:
undetectable		 5vv1A-3gyxB:
17.91
5vv1B-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.29A 5vv2A-3gyxA:
0.0
5vv2B-3gyxA:
2.6		 5vv2A-3gyxA:
20.86
5vv2B-3gyxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 5vv2A-3gyxB:
undetectable
5vv2B-3gyxB:
undetectable		 5vv2A-3gyxB:
17.91
5vv2B-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 5vv3A-3gyxA:
2.6
5vv3B-3gyxA:
undetectable		 5vv3A-3gyxA:
20.86
5vv3B-3gyxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 5vv3A-3gyxB:
undetectable
5vv3B-3gyxB:
undetectable		 5vv3A-3gyxB:
17.91
5vv3B-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 5vv4A-3gyxB:
undetectable
5vv4B-3gyxB:
undetectable		 5vv4A-3gyxB:
17.91
5vv4B-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.26A 5vv5A-3gyxA:
0.0
5vv5B-3gyxA:
2.7		 5vv5A-3gyxA:
20.86
5vv5B-3gyxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.24A 5vv5A-3gyxB:
undetectable
5vv5B-3gyxB:
undetectable		 5vv5A-3gyxB:
17.91
5vv5B-3gyxB:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 6 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.28A 6auqA-3gyxA:
undetectable
6auqB-3gyxA:
undetectable		 6auqA-3gyxA:
7.53
6auqB-3gyxA:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 6auqA-3gyxB:
undetectable
6auqB-3gyxB:
undetectable		 6auqA-3gyxB:
18.18
6auqB-3gyxB:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 6aurA-3gyxB:
undetectable
6aurB-3gyxB:
undetectable		 6aurA-3gyxB:
18.18
6aurB-3gyxB:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 6ausA-3gyxA:
undetectable
6ausB-3gyxA:
undetectable		 6ausA-3gyxA:
7.53
6ausB-3gyxA:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 6autA-3gyxA:
undetectable
6autB-3gyxA:
undetectable		 6autA-3gyxA:
7.53
6autB-3gyxA:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 6autA-3gyxB:
undetectable
6autB-3gyxB:
undetectable		 6autA-3gyxB:
18.18
6autB-3gyxB:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.29A 6auuA-3gyxA:
2.4
6auuB-3gyxA:
undetectable		 6auuA-3gyxA:
7.53
6auuB-3gyxA:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.26A 6auuA-3gyxB:
undetectable
6auuB-3gyxB:
undetectable		 6auuA-3gyxB:
18.18
6auuB-3gyxB:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 6auvA-3gyxA:
0.0
6auvB-3gyxA:
0.0		 6auvA-3gyxA:
7.53
6auvB-3gyxA:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.30A 6auvA-3gyxB:
undetectable
6auvB-3gyxB:
undetectable		 6auvA-3gyxB:
18.18
6auvB-3gyxB:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.32A 6auwA-3gyxA:
0.0
6auwB-3gyxA:
undetectable		 6auwA-3gyxA:
7.53
6auwB-3gyxA:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 6auwA-3gyxB:
undetectable
6auwB-3gyxB:
undetectable		 6auwA-3gyxB:
18.18
6auwB-3gyxB:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 6auxA-3gyxA:
undetectable
6auxB-3gyxA:
undetectable		 6auxA-3gyxA:
7.53
6auxB-3gyxA:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 6auxA-3gyxB:
undetectable
6auxB-3gyxB:
undetectable		 6auxA-3gyxB:
18.18
6auxB-3gyxB:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.29A 6auyA-3gyxA:
0.0
6auyB-3gyxA:
2.8		 6auyA-3gyxA:
8.72
6auyB-3gyxA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 6auzA-3gyxB:
undetectable
6auzB-3gyxB:
undetectable		 6auzA-3gyxB:
21.60
6auzB-3gyxB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 6av0A-3gyxA:
undetectable
6av0B-3gyxA:
2.9		 6av0A-3gyxA:
8.72
6av0B-3gyxA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 6av0A-3gyxB:
undetectable
6av0B-3gyxB:
undetectable		 6av0A-3gyxB:
21.60
6av0B-3gyxB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.25A 6av1A-3gyxA:
undetectable
6av1B-3gyxA:
undetectable		 6av1A-3gyxA:
8.72
6av1B-3gyxA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.28A 6av1A-3gyxB:
undetectable
6av1B-3gyxB:
undetectable		 6av1A-3gyxB:
21.60
6av1B-3gyxB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.29A 6av2A-3gyxA:
undetectable
6av2B-3gyxA:
undetectable		 6av2A-3gyxA:
8.72
6av2B-3gyxA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.29A 6av2A-3gyxB:
undetectable
6av2B-3gyxB:
undetectable		 6av2A-3gyxB:
21.60
6av2B-3gyxB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.31A 6av3A-3gyxA:
undetectable
6av3B-3gyxA:
2.9		 6av3A-3gyxA:
8.72
6av3B-3gyxA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 6av4A-3gyxA:
undetectable
6av4B-3gyxA:
undetectable		 6av4A-3gyxA:
8.72
6av4B-3gyxA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 6av4A-3gyxB:
undetectable
6av4B-3gyxB:
undetectable		 6av4A-3gyxB:
21.60
6av4B-3gyxB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.29A 6av5A-3gyxA:
undetectable
6av5B-3gyxA:
undetectable		 6av5A-3gyxA:
8.72
6av5B-3gyxA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas;
Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.29A 6cicA-3gyxA:
0.0
6cicB-3gyxA:
undetectable		 6cicA-3gyxA:
8.72
6cicB-3gyxA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_B_H4BB802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas;
Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.31A 6cicA-3gyxB:
undetectable
6cicB-3gyxB:
undetectable		 6cicA-3gyxB:
21.60
6cicB-3gyxB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas;
Desulfovibrio
gigas) 		4 / 7 ARG A  66
VAL A 387
TRP B  88
GLU A 380
 None
 1.30A 6cidA-3gyxA:
2.9
6cidB-3gyxA:
2.5		 6cidA-3gyxA:
8.72
6cidB-3gyxA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_B_H4BB803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gyx ADENYLYLSULFATE
REDUCTASE
ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas;
Desulfovibrio
gigas) 		4 / 7 TRP B  88
GLU A 380
ARG A  66
VAL A 387
 None
 1.32A 6cidA-3gyxB:
undetectable
6cidB-3gyxB:
undetectable		 6cidA-3gyxB:
21.60
6cidB-3gyxB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 3gyx ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas) 		3 / 3 HIS A 220
ASN A 213
LEU A 214
 None
 0.77A 6f7lB-3gyxA:
9.7		 6f7lB-3gyxA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3gyx ADENYLYLSULFATE
REDUCTASE
ADENYLYLSULFATE
REDUCTASE
(Desulfovibrio
gigas;
Desulfovibrio
gigas) 		5 / 10 SER A 242
GLY A 246
ALA B  71
LEU A 392
GLY A 286
 None
 1.14A 6hqbA-3gyxA:
undetectable
6hqbJ-3gyxA:
undetectable		 6hqbA-3gyxA:
9.06
6hqbJ-3gyxA:
5.25