SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gz5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQW_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN)		 3gz5 MUTT/NUDIX FAMILY
PROTEIN
(Shewanella
oneidensis) 		5 / 12 PHE A  27
THR A 103
VAL A  90
LEU A  52
ILE A 146
 None
 1.22A 1kqwA-3gz5A:
undetectable		 1kqwA-3gz5A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 3gz5 MUTT/NUDIX FAMILY
PROTEIN
(Shewanella
oneidensis) 		4 / 5 LEU A  38
GLY A  51
HIS A 142
ILE A 146
 None
 0.69A 1xf1A-3gz5A:
undetectable		 1xf1A-3gz5A:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_B_ACTB1108_0
(C5A PEPTIDASE)		 3gz5 MUTT/NUDIX FAMILY
PROTEIN
(Shewanella
oneidensis) 		4 / 6 LEU A  38
GLY A  51
HIS A 142
ILE A 146
 None
 0.74A 1xf1B-3gz5A:
undetectable		 1xf1B-3gz5A:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 3gz5 MUTT/NUDIX FAMILY
PROTEIN
(Shewanella
oneidensis) 		5 / 7 LEU A 203
LEU A 222
PHE A 171
LEU A 173
PRO A 163
 None
 1.00A 2vq5B-3gz5A:
undetectable		 2vq5B-3gz5A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_B_0LAB602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 3gz5 MUTT/NUDIX FAMILY
PROTEIN
(Shewanella
oneidensis) 		4 / 6 LEU A 176
LEU A 203
ILE A 204
THR A 226
 None
 1.01A 4do3B-3gz5A:
undetectable		 4do3B-3gz5A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 3gz5 MUTT/NUDIX FAMILY
PROTEIN
(Shewanella
oneidensis) 		4 / 5 LEU A  26
ALA A  24
LEU A  37
VAL A  22
 None
 1.11A 5cr1A-3gz5A:
undetectable		 5cr1A-3gz5A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA814_0
(UNCHARACTERIZED
PROTEIN)		 3gz5 MUTT/NUDIX FAMILY
PROTEIN
(Shewanella
oneidensis) 		4 / 5 TYR A 159
GLN A 155
THR A 154
LEU A 184
 None
 1.15A 6d8pA-3gz5A:
undetectable		 6d8pA-3gz5A:
15.22