SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gz7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 3gz7 PUTATIVE ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASE
(Bordetella
bronchiseptica) 		4 / 8 LEU A  52
HIS A  62
HIS A  91
ALA A   6
 CIT  A  97 (-4.5A)
CIT  A  97 (-3.6A)
None
CIT  A  97 ( 3.9A)
 0.86A 2bnnA-3gz7A:
undetectable
2bnnB-3gz7A:
undetectable		 2bnnA-3gz7A:
23.20
2bnnB-3gz7A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3gz7 PUTATIVE ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASE
(Bordetella
bronchiseptica) 		4 / 7 PHE A  83
SER A   7
VAL A  89
ARG A  76
 CIT  A  97 (-4.7A)
None
None
CIT  A  97 (-3.8A)
 1.29A 3dqtA-3gz7A:
undetectable
3dqtB-3gz7A:
undetectable		 3dqtA-3gz7A:
13.69
3dqtB-3gz7A:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 3gz7 PUTATIVE ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASE
(Bordetella
bronchiseptica) 		3 / 3 HIS A  91
HIS A  62
MET A  63
 None
CIT  A  97 (-3.6A)
None
 0.82A 3mihA-3gz7A:
2.4		 3mihA-3gz7A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3gz7 PUTATIVE ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASE
(Bordetella
bronchiseptica) 		4 / 7 SER A   7
VAL A  89
ARG A  76
PHE A  83
 None
None
CIT  A  97 (-3.8A)
CIT  A  97 (-4.7A)
 1.20A 3n5tA-3gz7A:
undetectable
3n5tB-3gz7A:
undetectable		 3n5tA-3gz7A:
12.81
3n5tB-3gz7A:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3gz7 PUTATIVE ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASE
(Bordetella
bronchiseptica) 		4 / 7 PHE A  83
SER A   7
VAL A  89
ARG A  76
 CIT  A  97 (-4.7A)
None
None
CIT  A  97 (-3.8A)
 1.23A 4k5jA-3gz7A:
undetectable
4k5jB-3gz7A:
undetectable		 4k5jA-3gz7A:
12.84
4k5jB-3gz7A:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 3gz7 PUTATIVE ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASE
(Bordetella
bronchiseptica) 		4 / 7 PHE A  83
SER A   7
VAL A  89
ARG A  76
 CIT  A  97 (-4.7A)
None
None
CIT  A  97 (-3.8A)
 1.24A 5adlA-3gz7A:
undetectable
5adlB-3gz7A:
undetectable		 5adlA-3gz7A:
12.84
5adlB-3gz7A:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3gz7 PUTATIVE ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASE
(Bordetella
bronchiseptica) 		4 / 7 PHE A  83
SER A   7
VAL A  89
ARG A  76
 CIT  A  97 (-4.7A)
None
None
CIT  A  97 (-3.8A)
 1.23A 5fj3A-3gz7A:
undetectable
5fj3B-3gz7A:
undetectable		 5fj3A-3gz7A:
12.84
5fj3B-3gz7A:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_H_ADNH401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 3gz7 PUTATIVE ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASE
(Bordetella
bronchiseptica) 		5 / 9 GLY A  21
VAL A  79
LEU A  28
VAL A  38
LEU A  52
 None
None
None
None
CIT  A  97 (-4.5A)
 1.04A 5lw1H-3gz7A:
undetectable		 5lw1H-3gz7A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3gz7 PUTATIVE ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASE
(Bordetella
bronchiseptica) 		4 / 7 PHE A  83
SER A   7
VAL A  89
ARG A  76
 CIT  A  97 (-4.7A)
None
None
CIT  A  97 (-3.8A)
 1.21A 5vv7A-3gz7A:
undetectable
5vv7B-3gz7A:
undetectable		 5vv7A-3gz7A:
12.84
5vv7B-3gz7A:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3gz7 PUTATIVE ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASE
(Bordetella
bronchiseptica) 		4 / 7 PHE A  83
SER A   7
VAL A  89
ARG A  76
 CIT  A  97 (-4.7A)
None
None
CIT  A  97 (-3.8A)
 1.27A 5vvnA-3gz7A:
undetectable
5vvnB-3gz7A:
undetectable		 5vvnA-3gz7A:
12.84
5vvnB-3gz7A:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3gz7 PUTATIVE ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASE
(Bordetella
bronchiseptica) 		4 / 7 SER A   7
VAL A  89
ARG A  76
PHE A  83
 None
None
CIT  A  97 (-3.8A)
CIT  A  97 (-4.7A)
 1.20A 6av6A-3gz7A:
undetectable
6av6B-3gz7A:
undetectable		 6av6A-3gz7A:
21.30
6av6B-3gz7A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3gz7 PUTATIVE ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASE
(Bordetella
bronchiseptica) 		4 / 7 PHE A  83
SER A   7
VAL A  89
ARG A  76
 CIT  A  97 (-4.7A)
None
None
CIT  A  97 (-3.8A)
 1.11A 6av6C-3gz7A:
undetectable
6av6D-3gz7A:
undetectable		 6av6C-3gz7A:
21.30
6av6D-3gz7A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3gz7 PUTATIVE ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASE
(Bordetella
bronchiseptica) 		4 / 7 SER A   7
VAL A  89
ARG A  76
PHE A  83
 None
None
CIT  A  97 (-3.8A)
CIT  A  97 (-4.7A)
 1.24A 6av7A-3gz7A:
undetectable
6av7B-3gz7A:
undetectable		 6av7A-3gz7A:
21.30
6av7B-3gz7A:
21.30