SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gzb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3gzb PUTATIVE SNOAL-LIKE
POLYKETIDE CYCLASE
(Shewanella
putrefaciens) 		5 / 10 GLY A 103
GLY A 105
VAL A  76
HIS A  73
VAL A 117
 None
None
None
MRD  A 154 (-4.0A)
None
 1.32A 4c5nB-3gzbA:
undetectable		 4c5nB-3gzbA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)		 3gzb PUTATIVE SNOAL-LIKE
POLYKETIDE CYCLASE
(Shewanella
putrefaciens) 		3 / 3 ASP A  47
ARG A  46
ASP A 128
 None
 0.59A 4fp9A-3gzbA:
undetectable		 4fp9A-3gzbA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 3gzb PUTATIVE SNOAL-LIKE
POLYKETIDE CYCLASE
(Shewanella
putrefaciens) 		3 / 3 ASP A  47
ARG A  46
ASP A 128
 None
 0.55A 4fp9C-3gzbA:
undetectable		 4fp9C-3gzbA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 3gzb PUTATIVE SNOAL-LIKE
POLYKETIDE CYCLASE
(Shewanella
putrefaciens) 		3 / 3 ASP A  47
ARG A  46
ASP A 128
 None
 0.54A 4fp9F-3gzbA:
undetectable		 4fp9F-3gzbA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 3gzb PUTATIVE SNOAL-LIKE
POLYKETIDE CYCLASE
(Shewanella
putrefaciens) 		5 / 12 ILE A  96
GLY A  97
ASN A  82
PRO A 120
ALA A 118
 None
 1.02A 4rvgA-3gzbA:
undetectable		 4rvgA-3gzbA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_2
(THYROXINE-BINDING
GLOBULIN)		 3gzb PUTATIVE SNOAL-LIKE
POLYKETIDE CYCLASE
(Shewanella
putrefaciens) 		3 / 3 LEU A 130
ARG A 133
ARG A 132
 None
 0.84A 4yiaB-3gzbA:
undetectable		 4yiaB-3gzbA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3gzb PUTATIVE SNOAL-LIKE
POLYKETIDE CYCLASE
(Shewanella
putrefaciens) 		4 / 6 TYR A  28
ASP A 139
HIS A 137
ILE A  49
 None
MRD  A 154 (-4.6A)
None
None
 1.27A 5ih0A-3gzbA:
undetectable		 5ih0A-3gzbA:
19.93