SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gzr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3gzr UNCHARACTERIZED
PROTEIN WITH A
NTF2-LIKE FOLD
(Caulobacter
vibrioides) 		5 / 12 LEU A 139
HIS A  83
LEU A 137
THR A 138
GLY A  70
 None
 1.15A 1jffB-3gzrA:
undetectable		 1jffB-3gzrA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_B_ACTB704_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 3gzr UNCHARACTERIZED
PROTEIN WITH A
NTF2-LIKE FOLD
(Caulobacter
vibrioides) 		3 / 3 ARG A 144
GLY A  63
ASP A  62
 None
 0.52A 1kf6A-3gzrA:
undetectable
1kf6B-3gzrA:
undetectable		 1kf6A-3gzrA:
12.24
1kf6B-3gzrA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3gzr UNCHARACTERIZED
PROTEIN WITH A
NTF2-LIKE FOLD
(Caulobacter
vibrioides) 		5 / 12 LEU A 139
HIS A  83
LEU A 137
THR A 138
GLY A  70
 None
 1.15A 2hxfB-3gzrA:
undetectable		 2hxfB-3gzrA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3gzr UNCHARACTERIZED
PROTEIN WITH A
NTF2-LIKE FOLD
(Caulobacter
vibrioides) 		5 / 12 LEU A 139
HIS A  83
LEU A 137
THR A 138
GLY A  70
 None
 1.15A 2hxhB-3gzrA:
undetectable		 2hxhB-3gzrA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3gzr UNCHARACTERIZED
PROTEIN WITH A
NTF2-LIKE FOLD
(Caulobacter
vibrioides) 		5 / 12 LEU A 139
HIS A  83
LEU A 137
THR A 138
GLY A  70
 None
 1.14A 2p4nB-3gzrA:
undetectable		 2p4nB-3gzrA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 3gzr UNCHARACTERIZED
PROTEIN WITH A
NTF2-LIKE FOLD
(Caulobacter
vibrioides) 		5 / 12 LEU A 139
HIS A  83
LEU A 137
THR A 138
GLY A  70
 None
 1.15A 2wbeB-3gzrA:
undetectable		 2wbeB-3gzrA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 3gzr UNCHARACTERIZED
PROTEIN WITH A
NTF2-LIKE FOLD
(Caulobacter
vibrioides) 		5 / 12 LEU A 139
HIS A  83
LEU A 137
THR A 138
GLY A  70
 None
 1.15A 3dcoB-3gzrA:
undetectable		 3dcoB-3gzrA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 3gzr UNCHARACTERIZED
PROTEIN WITH A
NTF2-LIKE FOLD
(Caulobacter
vibrioides) 		5 / 12 LEU A 139
HIS A  83
LEU A 137
THR A 138
GLY A  70
 None
 1.15A 3edlB-3gzrA:
undetectable		 3edlB-3gzrA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3gzr UNCHARACTERIZED
PROTEIN WITH A
NTF2-LIKE FOLD
(Caulobacter
vibrioides) 		4 / 7 THR A 100
GLU A 102
VAL A 114
THR A 116
 None
 0.65A 3em0B-3gzrA:
2.6		 3em0B-3gzrA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 3gzr UNCHARACTERIZED
PROTEIN WITH A
NTF2-LIKE FOLD
(Caulobacter
vibrioides) 		5 / 12 LEU A 139
HIS A  83
LEU A 137
THR A 138
GLY A  70
 None
 1.12A 3iz0B-3gzrA:
undetectable		 3iz0B-3gzrA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 3gzr UNCHARACTERIZED
PROTEIN WITH A
NTF2-LIKE FOLD
(Caulobacter
vibrioides) 		5 / 11 ARG A 104
ALA A 141
ILE A  40
GLY A 153
ILE A  36
 None
 1.07A 3s53B-3gzrA:
undetectable		 3s53B-3gzrA:
17.48