SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gzt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FE2_A_LAXA700_1 (PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1)	3gzt	OUTER CAPSID GLYCOPROTEIN VP7 (Rotavirus A)	5 / 10	VAL B 116 VAL B 295 VAL B 299 ILE B 307 LEU B 83	None	0.96A	1fe2A-3gztB: undetectable	1fe2A-3gztB: 17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KPC_A_SAMA1000_0 (UNCHARACTERIZED PROTEIN MJ0100)	3gzt	OUTER CAPSID GLYCOPROTEIN VP7 (Rotavirus A)	5 / 11	THR B 75 VAL B 303 ILE B 306 ASN B 257 SER B 311	None	1.11A	3kpcA-3gztB: undetectable	3kpcA-3gztB: 19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RUN_A_CCSA165_0 (LYSOZYME)	3gzt	OUTER CAPSID GLYCOPROTEIN VP7 (Rotavirus A)	3 / 3	ASN B 182 ALA B 181 LYS B 183	None None CA B 322 ( 4.5A)	0.87A	3runA-3gztB: undetectable	3runA-3gztB: 19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I3C_A_AC2A301_1 (PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE)	3gzt	OUTER CAPSID GLYCOPROTEIN VP7 (Rotavirus A)	5 / 9	SER B 186 GLY B 188 ALA B 125 VAL B 129 GLU B 154	None	1.41A	5i3cA-3gztB: undetectable	5i3cA-3gztB: 22.76

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FE2_A_LAXA700_1","PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1","3gzt","OUTER CAPSID GLYCOPROTEIN VP7","Rotavirus A",5,"VAL B 116;VAL B 295;VAL B 299;ILE B 307;LEU B  83","None","0.96A","1fe2A-3gztB:undetectable","1fe2A-3gztB:17.48"],["3KPC_A_SAMA1000_0","UNCHARACTERIZED PROTEIN MJ0100","3gzt","OUTER CAPSID GLYCOPROTEIN VP7","Rotavirus A",5,"THR B  75;VAL B 303;ILE B 306;ASN B 257;SER B 311","None","1.11A","3kpcA-3gztB:undetectable","3kpcA-3gztB:19.14"],["3RUN_A_CCSA165_0","LYSOZYME","3gzt","OUTER CAPSID GLYCOPROTEIN VP7","Rotavirus A",3,"ASN B 182;ALA B 181;LYS B 183","None;None; CA B 322 ( 4.5A)","0.87A","3runA-3gztB:undetectable","3runA-3gztB:19.05"],["5I3C_A_AC2A301_1","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","3gzt","OUTER CAPSID GLYCOPROTEIN VP7","Rotavirus A",5,"SER B 186;GLY B 188;ALA B 125;VAL B 129;GLU B 154","None","1.41A","5i3cA-3gztB:undetectable","5i3cA-3gztB:22.76"]]