SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3gzy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
(Comamonas
testosteroni) 		4 / 8 PHE A 173
MET A  60
THR A 205
LEU A 198
 None
 0.92A 1ea1A-3gzyA:
undetectable		 1ea1A-3gzyA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3002_1
(SERUM ALBUMIN)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 8 GLN B  22
LEU B  21
LEU B 154
SER B 130
 None
 1.16A 1hk2A-3gzyB:
undetectable		 1hk2A-3gzyB:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_4
(HIV-1 PROTEASE)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
(Comamonas
testosteroni) 		4 / 4 GLY A 387
ASP A 385
GLY A 380
THR A 336
 None
 1.07A 1hxbB-3gzyA:
undetectable		 1hxbB-3gzyA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni;
Comamonas
testosteroni) 		4 / 4 GLY A 246
LEU A 247
GLY B  89
ARG B  92
 None
 1.28A 1j7kA-3gzyA:
undetectable		 1j7kA-3gzyA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
(Comamonas
testosteroni) 		3 / 3 TRP A 452
HIS A 442
MET A 446
 None
 1.08A 1l5qB-3gzyA:
undetectable		 1l5qB-3gzyA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
(Comamonas
testosteroni) 		3 / 3 ARG A 343
VAL A 350
TRP A 351
 None
 1.21A 1qwcA-3gzyA:
undetectable		 1qwcA-3gzyA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 7 PHE B 185
PHE B  41
SER B 106
ARG B 136
 None
 1.23A 1rqpB-3gzyB:
undetectable		 1rqpB-3gzyB:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SKX_A_RFPA1_1
(ORPHAN NUCLEAR
RECEPTOR PXR)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
(Comamonas
testosteroni) 		5 / 12 VAL A  95
TRP A 176
HIS A 341
ILE A 211
PHE A 353
 None
 1.48A 1skxA-3gzyA:
undetectable		 1skxA-3gzyA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 7 ILE B 165
LEU B  48
ARG B  31
LEU B  36
 None
 0.85A 1v54N-3gzyB:
undetectable
1v54W-3gzyB:
undetectable		 1v54N-3gzyB:
15.34
1v54W-3gzyB:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 7 ILE B 165
LEU B  48
ARG B  31
LEU B  36
 None
 0.86A 1v55A-3gzyB:
undetectable
1v55J-3gzyB:
undetectable		 1v55A-3gzyB:
15.34
1v55J-3gzyB:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 8 ILE B 165
LEU B  48
ARG B  31
LEU B  36
 None
 0.80A 1v55N-3gzyB:
undetectable
1v55W-3gzyB:
undetectable		 1v55N-3gzyB:
15.34
1v55W-3gzyB:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XL6_B_SPMB3001_1
(INWARD RECTIFIER
POTASSIUM CHANNEL)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
(Comamonas
testosteroni) 		4 / 5 ALA A 432
TYR A 431
ALA A 428
TYR A 429
 None
 1.02A 1xl6A-3gzyA:
undetectable
1xl6B-3gzyA:
undetectable		 1xl6A-3gzyA:
23.08
1xl6B-3gzyA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AKE_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
(Comamonas
testosteroni) 		5 / 12 TYR A 295
GLY A 204
THR A 201
GLU A 202
ILE A 364
 None
 1.34A 2akeA-3gzyA:
undetectable		 2akeA-3gzyA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA601_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
(Comamonas
testosteroni) 		5 / 12 TYR A 295
GLY A 204
THR A 201
GLU A 202
ILE A 364
 None
 1.34A 2azxA-3gzyA:
undetectable		 2azxA-3gzyA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 7 ILE B 165
LEU B  48
ARG B  31
LEU B  36
 None
 0.82A 2dyrN-3gzyB:
undetectable
2dyrW-3gzyB:
undetectable		 2dyrN-3gzyB:
15.34
2dyrW-3gzyB:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 8 ILE B 165
LEU B  48
ARG B  31
LEU B  36
 None
 0.77A 2eijN-3gzyB:
undetectable
2eijW-3gzyB:
undetectable		 2eijN-3gzyB:
15.34
2eijW-3gzyB:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 8 ILE B 165
LEU B  48
ARG B  31
LEU B  36
 None
 0.92A 2einA-3gzyB:
undetectable
2einJ-3gzyB:
undetectable		 2einA-3gzyB:
15.34
2einJ-3gzyB:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		5 / 12 LEU B 172
ASP B 144
ALA B  33
VAL B 184
TYR B  54
 None
 1.15A 2g70A-3gzyB:
undetectable		 2g70A-3gzyB:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		5 / 12 LEU B 172
ASP B 144
ALA B  33
VAL B 184
TYR B  54
 None
 1.19A 2g70B-3gzyB:
undetectable		 2g70B-3gzyB:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
(Comamonas
testosteroni) 		3 / 3 ARG A 374
GLY A 289
PRO A 290
 None
 0.52A 2hreD-3gzyA:
undetectable		 2hreD-3gzyA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni;
Comamonas
testosteroni) 		3 / 3 GLY A 112
ARG B  62
TYR A  73
 None
 0.85A 2opxA-3gzyA:
undetectable		 2opxA-3gzyA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_A_CLUA808_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
(Comamonas
testosteroni) 		4 / 7 ALA A 274
TYR A 193
MET A 317
HIS A 321
 None
 1.25A 2pncA-3gzyA:
undetectable		 2pncA-3gzyA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_B_CLUB809_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
(Comamonas
testosteroni) 		4 / 6 ALA A 274
TYR A 193
MET A 317
HIS A 321
 None
 1.36A 2pncB-3gzyA:
undetectable		 2pncB-3gzyA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1299_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 7 PHE B 185
PHE B  41
SER B 106
ARG B 136
 None
 1.28A 2v7uB-3gzyB:
undetectable		 2v7uB-3gzyB:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni;
Comamonas
testosteroni) 		3 / 3 TYR A  73
GLU B  66
THR B  60
 None
 0.99A 2y7hB-3gzyA:
undetectable		 2y7hB-3gzyA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 8 ILE B 165
LEU B  48
ARG B  31
LEU B  36
 None
 0.84A 3abkA-3gzyB:
undetectable
3abkJ-3gzyB:
undetectable		 3abkA-3gzyB:
15.34
3abkJ-3gzyB:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 8 ILE B 165
LEU B  48
ARG B  31
LEU B  36
 None
 0.82A 3abmN-3gzyB:
undetectable
3abmW-3gzyB:
undetectable		 3abmN-3gzyB:
15.34
3abmW-3gzyB:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 7 ILE B 165
LEU B  48
ARG B  31
LEU B  36
 None
 0.88A 3ag3A-3gzyB:
undetectable
3ag3J-3gzyB:
undetectable		 3ag3A-3gzyB:
15.34
3ag3J-3gzyB:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 8 ILE B 165
LEU B  48
ARG B  31
LEU B  36
 None
 0.89A 3ag3N-3gzyB:
undetectable
3ag3W-3gzyB:
undetectable		 3ag3N-3gzyB:
15.34
3ag3W-3gzyB:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 8 ILE B 165
LEU B  48
ARG B  31
LEU B  36
 None
 0.81A 3asnN-3gzyB:
undetectable
3asnW-3gzyB:
undetectable		 3asnN-3gzyB:
15.34
3asnW-3gzyB:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 8 ILE B 165
LEU B  48
ARG B  31
LEU B  36
 None
 0.79A 3asoN-3gzyB:
undetectable
3asoW-3gzyB:
undetectable		 3asoN-3gzyB:
15.34
3asoW-3gzyB:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
(Comamonas
testosteroni) 		5 / 12 LEU A  35
ILE A  24
GLU A 433
ALA A 409
ASP A  36
 None
 1.25A 3axtA-3gzyA:
undetectable		 3axtA-3gzyA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DLC_A_SAMA220_0
(PUTATIVE
S-ADENOSYL-L-METHION
INE-DEPENDENT
METHYLTRANSFERASE)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
(Comamonas
testosteroni) 		5 / 12 GLY A 271
GLY A 438
SER A 229
VAL A 324
SER A 267
 None
 1.01A 3dlcA-3gzyA:
undetectable		 3dlcA-3gzyA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		3 / 3 TYR B  54
ASP B 152
HIS B 110
 None
 0.69A 3e23A-3gzyB:
undetectable		 3e23A-3gzyB:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
(Comamonas
testosteroni) 		3 / 3 ASP A 386
PHE A 376
SER A 329
 FE2  A 701 (-1.9A)
None
None
 0.86A 3i5uB-3gzyA:
undetectable		 3i5uB-3gzyA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_2
(HIV-1 PROTEASE)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
(Comamonas
testosteroni) 		4 / 4 GLY A 387
ASP A 385
GLY A 380
THR A 336
 None
 1.01A 3k4vC-3gzyA:
undetectable		 3k4vC-3gzyA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
(Comamonas
testosteroni) 		4 / 8 ASP A  36
TYR A  40
LEU A  45
LEU A  27
 None
 1.03A 3lm8B-3gzyA:
undetectable
3lm8D-3gzyA:
undetectable		 3lm8B-3gzyA:
21.04
3lm8D-3gzyA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni;
Comamonas
testosteroni) 		3 / 3 GLY A 379
TRP A 214
VAL B 177
 None
 0.65A 3n62B-3gzyA:
undetectable		 3n62B-3gzyA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni;
Comamonas
testosteroni) 		3 / 3 GLY A 379
TRP A 214
VAL B 177
 None
 0.66A 3n65B-3gzyA:
undetectable		 3n65B-3gzyA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni;
Comamonas
testosteroni) 		3 / 3 GLY A 379
TRP A 214
VAL B 177
 None
 0.65A 3n66B-3gzyA:
undetectable		 3n66B-3gzyA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A2000_1
(P38A)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
(Comamonas
testosteroni) 		5 / 12 ASP A  42
ILE A  39
MET A 397
ALA A  41
TYR A  40
 None
 1.10A 3ohtA-3gzyA:
undetectable
3ohtB-3gzyA:
undetectable		 3ohtA-3gzyA:
20.21
3ohtB-3gzyA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni;
Comamonas
testosteroni) 		4 / 7 ASP B  82
PHE B  80
GLY A 379
THR B  86
 None
 1.12A 3vnsA-3gzyB:
undetectable		 3vnsA-3gzyB:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni;
Comamonas
testosteroni) 		4 / 7 ASP B  82
PHE B  80
GLY A 380
THR B  86
 None
 0.84A 3vnsA-3gzyB:
undetectable		 3vnsA-3gzyB:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
(Comamonas
testosteroni) 		3 / 3 PHE A 325
VAL A  53
GLU A  49
 None
 0.83A 4fvqA-3gzyA:
undetectable		 4fvqA-3gzyA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
(Comamonas
testosteroni) 		4 / 7 ILE A 337
CYH A 328
LEU A 187
MET A 197
 None
 0.85A 4xumA-3gzyA:
undetectable		 4xumA-3gzyA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 7 ILE B 165
LEU B  48
ARG B  31
LEU B  36
 None
 0.79A 5b1bA-3gzyB:
undetectable
5b1bJ-3gzyB:
undetectable		 5b1bA-3gzyB:
15.34
5b1bJ-3gzyB:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
(Comamonas
testosteroni) 		3 / 3 ARG A 343
VAL A 350
TRP A 351
 None
 1.23A 5fvoA-3gzyA:
undetectable		 5fvoA-3gzyA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 7 ILE B 165
LEU B  48
ARG B  31
LEU B  36
 None
 0.79A 5iy5A-3gzyB:
undetectable
5iy5J-3gzyB:
undetectable		 5iy5A-3gzyB:
15.34
5iy5J-3gzyB:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1103_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 8 GLN B 174
ASP B 144
GLY A 379
ARG B  90
 None
 1.04A 5nzyA-3gzyB:
undetectable		 5nzyA-3gzyB:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
(Comamonas
testosteroni) 		5 / 12 VAL A  83
LEU A  97
LEU A  50
ALA A 163
LEU A  59
 None
 1.15A 5og9B-3gzyA:
undetectable		 5og9B-3gzyA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
(Comamonas
testosteroni) 		4 / 7 TYR A 431
TYR A 429
ASP A 230
HIS A 321
 None
 1.18A 5ov9B-3gzyA:
undetectable		 5ov9B-3gzyA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni;
Comamonas
testosteroni) 		3 / 3 GLY A 379
TRP A 214
VAL B 177
 None
 0.65A 5vuoB-3gzyA:
undetectable		 5vuoB-3gzyA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 7 ILE B 165
LEU B  48
ARG B  31
LEU B  36
 None
 0.93A 5xdqA-3gzyB:
undetectable
5xdqJ-3gzyB:
undetectable		 5xdqA-3gzyB:
15.34
5xdqJ-3gzyB:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 7 ILE B 165
LEU B  48
ARG B  31
LEU B  36
 None
 0.79A 5xdqN-3gzyB:
undetectable
5xdqW-3gzyB:
undetectable		 5xdqN-3gzyB:
15.34
5xdqW-3gzyB:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 8 ILE B 165
LEU B  48
ARG B  31
LEU B  36
 None
 0.76A 5xdxN-3gzyB:
undetectable
5xdxW-3gzyB:
undetectable		 5xdxN-3gzyB:
15.34
5xdxW-3gzyB:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 8 ILE B 165
LEU B  48
ARG B  31
LEU B  36
 None
 0.83A 5zcpN-3gzyB:
undetectable
5zcpW-3gzyB:
undetectable		 5zcpN-3gzyB:
15.34
5zcpW-3gzyB:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 8 ILE B 165
LEU B  48
ARG B  31
LEU B  36
 None
 0.91A 5zcqN-3gzyB:
undetectable
5zcqW-3gzyB:
undetectable		 5zcqN-3gzyB:
15.34
5zcqW-3gzyB:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_A_P2EA1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT ALPHA
(Comamonas
testosteroni) 		4 / 4 PRO A 424
MET A 317
GLY A 319
VAL A 196
 None
 1.38A 6ak3A-3gzyA:
undetectable		 6ak3A-3gzyA:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J21_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		5 / 12 ASN B 181
VAL B 143
HIS B 110
PHE B 146
PHE B 186
 None
 1.49A 6j21A-3gzyB:
undetectable		 6j21A-3gzyB:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3gzy BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Comamonas
testosteroni) 		4 / 5 ILE B 165
LEU B  48
ARG B  31
LEU B  36
 None
 0.83A 6nmpN-3gzyB:
undetectable
6nmpW-3gzyB:
undetectable		 6nmpN-3gzyB:
15.34
6nmpW-3gzyB:
18.35