SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h04'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 3h04 UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 GLY A  37
GLY A  38
GLY A  39
SER A 104
HIS A 248
 None
 0.17A 1dx6A-3h04A:
16.2		 1dx6A-3h04A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_B_RBFB502_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3h04 UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 11 ILE A 113
LEU A 112
GLY A 106
SER A 105
LEU A  40
 None
 1.47A 1kyvA-3h04A:
3.3
1kyvB-3h04A:
3.2		 1kyvA-3h04A:
20.36
1kyvB-3h04A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_2
(ESTROGEN RECEPTOR
BETA)		 3h04 UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		3 / 3 ASP A  47
LEU A  48
HIS A 216
 None
 0.63A 1qknA-3h04A:
undetectable		 1qknA-3h04A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 3h04 UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 GLY A  37
GLY A  38
GLY A  39
SER A 104
HIS A 248
 None
 0.22A 1qtiA-3h04A:
15.8		 1qtiA-3h04A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 3h04 UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 11 GLY A 127
ALA A 107
LEU A 112
VAL A 212
VAL A 122
 None
 1.08A 1ukbA-3h04A:
19.2		 1ukbA-3h04A:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)		 3h04 UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 GLY A  37
GLY A  38
GLY A  39
SER A 104
HIS A 248
 None
 0.20A 1w6rA-3h04A:
16.2		 1w6rA-3h04A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3h04 UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 THR A 100
PRO A 210
VAL A  82
TYR A  83
LEU A  65
 None
 1.44A 1z9hA-3h04A:
undetectable		 1z9hA-3h04A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3h04 UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 THR A 100
PRO A 210
VAL A  82
TYR A  83
LEU A  65
 None
 1.45A 1z9hB-3h04A:
undetectable		 1z9hB-3h04A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3h04 UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 THR A 100
PRO A 210
VAL A  82
TYR A  83
LEU A  65
 None
 1.44A 1z9hC-3h04A:
undetectable		 1z9hC-3h04A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8L_A_SAMA400_1
(HYPOTHETICAL PROTEIN
LMO1582)		 3h04 UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 4 THR A  28
THR A 273
ASP A 120
ASP A 118
 None
 1.45A 2f8lA-3h04A:
undetectable		 2f8lA-3h04A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_A_STIA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3h04 UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 6 LEU A  16
VAL A  73
ILE A  79
ARG A 180
 None
 1.01A 2hyyA-3h04A:
undetectable		 2hyyA-3h04A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 3h04 UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 7 ILE A 146
ILE A 175
LEU A 158
ILE A 155
 None
 0.86A 2q83A-3h04A:
undetectable		 2q83A-3h04A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_A_BEZA999_0
(CHOLINESTERASE)		 3h04 UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 7 GLY A  38
GLY A  39
SER A 104
HIS A 248
 None
 0.29A 3o9mA-3h04A:
16.2		 3o9mA-3h04A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 3h04 UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 6 GLY A  38
GLY A  39
SER A 104
HIS A 248
 None
 0.35A 3o9mB-3h04A:
16.2		 3o9mB-3h04A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 3h04 UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 GLY A  37
GLY A  38
GLY A  39
SER A 104
HIS A 248
 None
 0.15A 4ey6A-3h04A:
15.8		 4ey6A-3h04A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 3h04 UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 GLY A  37
GLY A  38
GLY A  39
SER A 104
HIS A 248
 None
 0.22A 4ey6B-3h04A:
15.6		 4ey6B-3h04A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 3h04 UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 6 SER A  74
LEU A  75
ASP A  76
LEU A  70
 None
 0.91A 4wozA-3h04A:
undetectable
4wozB-3h04A:
undetectable		 4wozA-3h04A:
24.77
4wozB-3h04A:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)		 3h04 UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 ALA A 107
GLY A 106
LYS A  44
ASN A  46
LEU A  65
 None
 1.26A 5nwuA-3h04A:
undetectable		 5nwuA-3h04A:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 3h04 UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		3 / 3 ARG A 180
PRO A 135
TYR A 221
 None
 1.06A 5tzoB-3h04A:
undetectable		 5tzoB-3h04A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 3h04 UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 8 GLY A 127
TRP A 185
VAL A 223
ASP A 222
 None
 0.85A 5vlmA-3h04A:
undetectable		 5vlmA-3h04A:
21.40