SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h07'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 3h07 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE
(Yersinia
pestis) 		5 / 11 HIS A 153
VAL A  31
CYH A  69
GLY A 142
ILE A 158
 None
 1.26A 2uxpB-3h07A:
undetectable		 2uxpB-3h07A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)		 3h07 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE
(Yersinia
pestis) 		5 / 12 ILE A 122
VAL A 137
ILE A  59
VAL A  66
VAL A 171
 None
 1.07A 3iw1A-3h07A:
undetectable		 3iw1A-3h07A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 3h07 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE
(Yersinia
pestis) 		4 / 6 LEU A   6
SER A   7
PHE A   9
ILE A 189
 None
 0.96A 3ko0B-3h07A:
undetectable		 3ko0B-3h07A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 3h07 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE
(Yersinia
pestis) 		5 / 12 ALA A 185
HIS A 184
GLY A  41
ALA A 156
ASN A  39
 None
 1.11A 3tm4A-3h07A:
undetectable		 3tm4A-3h07A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)		 3h07 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE
(Yersinia
pestis) 		3 / 3 ASP A 204
VAL A  31
LEU A 160
 None
 0.67A 5e5jB-3h07A:
undetectable		 5e5jB-3h07A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 3h07 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE
(Yersinia
pestis) 		5 / 12 GLY A  28
VAL A 200
ALA A 161
LEU A 160
ALA A 156
 None
 0.88A 5kpcA-3h07A:
undetectable		 5kpcA-3h07A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA511_1
(PROTON-GATED ION
CHANNEL)		 3h07 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE
(Yersinia
pestis) 		4 / 8 PRO A 139
ILE A 118
ALA A 121
ILE A 122
 None
 0.67A 5mvmA-3h07A:
undetectable
5mvmB-3h07A:
undetectable		 5mvmA-3h07A:
16.75
5mvmB-3h07A:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_0
(REGULATORY PROTEIN
TETR)		 3h07 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE
(Yersinia
pestis) 		5 / 12 MET A  55
GLN A  54
LEU A 115
ILE A 118
CYH A  69
 None
 1.33A 5vlmB-3h07A:
undetectable		 5vlmB-3h07A:
24.38