SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h09'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4004_1
(SERUM ALBUMIN)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 4 VAL A 177
PHE A 523
SER A  78
VAL A  79
 None
 1.46A 1e7cA-3h09A:
undetectable		 1e7cA-3h09A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_1
(HIV-1 PROTEASE)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 9 GLY A 660
ILE A 499
GLY A 522
ILE A 543
ILE A 540
 None
None
None
None
ACT  A1800 (-4.0A)
 1.01A 1hpvA-3h09A:
undetectable		 1hpvA-3h09A:
7.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_2
(PROTEASE)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 11 GLY A 660
ILE A 499
GLY A 522
ILE A 543
ILE A 540
 None
None
None
None
ACT  A1800 (-4.0A)
 0.91A 1n49B-3h09A:
undetectable		 1n49B-3h09A:
8.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_1
(PROTEASE)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 11 GLY A 660
ILE A 499
GLY A 522
ILE A 543
ILE A 540
 None
None
None
None
ACT  A1800 (-4.0A)
 0.90A 1n49C-3h09A:
undetectable		 1n49C-3h09A:
8.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 8 THR A 689
LEU A 687
VAL A 801
VAL A 737
 None
 1.08A 1o76B-3h09A:
undetectable		 1o76B-3h09A:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 12 TYR A 520
GLY A 546
GLY A 660
ILE A 543
THR A 175
 None
 1.04A 1p91B-3h09A:
undetectable		 1p91B-3h09A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_0
(HEMK PROTEIN)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 12 PRO A 291
GLY A 207
GLY A 205
ILE A  86
ALA A 283
 None
 0.97A 1sg9B-3h09A:
undetectable		 1sg9B-3h09A:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 6 VAL A 389
ILE A 403
ILE A 360
ASP A 370
 None
 0.86A 1uwhB-3h09A:
undetectable		 1uwhB-3h09A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.44A 1v54A-3h09A:
undetectable		 1v54A-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.46A 1v54N-3h09A:
undetectable		 1v54N-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.47A 1v55A-3h09A:
undetectable		 1v55A-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.46A 1v55N-3h09A:
undetectable		 1v55N-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 8 ASP A 580
TYR A 608
THR A 575
PRO A 576
 None
 0.97A 1z2bB-3h09A:
undetectable		 1z2bB-3h09A:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.42A 2dyrA-3h09A:
undetectable		 2dyrA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.46A 2dyrN-3h09A:
undetectable		 2dyrN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.46A 2dysA-3h09A:
undetectable		 2dysA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.44A 2dysN-3h09A:
undetectable		 2dysN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.44A 2eijA-3h09A:
undetectable		 2eijA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.45A 2eijN-3h09A:
undetectable		 2eijN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.43A 2eikA-3h09A:
undetectable		 2eikA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.47A 2eikN-3h09A:
undetectable		 2eikN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.44A 2eilA-3h09A:
undetectable		 2eilA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.48A 2eilN-3h09A:
undetectable		 2eilN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.46A 2eimA-3h09A:
undetectable		 2eimA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.49A 2eimN-3h09A:
undetectable		 2eimN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.47A 2einA-3h09A:
undetectable		 2einA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.47A 2einN-3h09A:
undetectable		 2einN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 8 TYR A 165
GLY A 306
THR A  88
ILE A  90
 None
 0.83A 2f9wA-3h09A:
undetectable
2f9wB-3h09A:
undetectable		 2f9wA-3h09A:
14.20
2f9wB-3h09A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 11 LEU A 410
LEU A 391
ILE A 403
PRO A 353
ASN A 352
 None
None
None
MLA  A2100 (-3.9A)
None
 1.18A 2ft9A-3h09A:
undetectable		 2ft9A-3h09A:
8.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 879
HIS A 861
HIS A 859
 None
 0.70A 2oqeA-3h09A:
undetectable		 2oqeA-3h09A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 879
HIS A 861
HIS A 859
 None
 0.69A 2oqeB-3h09A:
undetectable		 2oqeB-3h09A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 879
HIS A 861
HIS A 859
 None
 0.71A 2oqeC-3h09A:
undetectable		 2oqeC-3h09A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 879
HIS A 861
HIS A 859
 None
 0.68A 2oqeD-3h09A:
undetectable		 2oqeD-3h09A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 879
HIS A 861
HIS A 859
 None
 0.71A 2oqeF-3h09A:
undetectable		 2oqeF-3h09A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 12 GLY A 242
GLY A 236
SER A 206
ASP A 216
ILE A 211
 None
 1.15A 2wa2A-3h09A:
undetectable		 2wa2A-3h09A:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 7 ILE A 461
LEU A 460
VAL A 434
GLY A 458
 None
 0.81A 2wd9A-3h09A:
undetectable		 2wd9A-3h09A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.45A 2y69A-3h09A:
undetectable		 2y69A-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.43A 2y69N-3h09A:
undetectable		 2y69N-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 8 ILE A  86
SER A 137
TYR A 239
SER A 102
 None
 1.03A 2zw9B-3h09A:
undetectable		 2zw9B-3h09A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.48A 2zxwA-3h09A:
undetectable		 2zxwA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.46A 2zxwN-3h09A:
undetectable		 2zxwN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.46A 3abkA-3h09A:
undetectable		 3abkA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.43A 3abkN-3h09A:
undetectable		 3abkN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.45A 3ablA-3h09A:
undetectable		 3ablA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.47A 3ablN-3h09A:
undetectable		 3ablN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.45A 3abmA-3h09A:
undetectable		 3abmA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.42A 3abmN-3h09A:
undetectable		 3abmN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.44A 3ag1A-3h09A:
undetectable		 3ag1A-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.41A 3ag1N-3h09A:
undetectable		 3ag1N-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.43A 3ag2A-3h09A:
undetectable		 3ag2A-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.46A 3ag2N-3h09A:
undetectable		 3ag2N-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.43A 3ag3A-3h09A:
undetectable		 3ag3A-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.42A 3ag3N-3h09A:
undetectable		 3ag3N-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.46A 3ag4A-3h09A:
undetectable		 3ag4A-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.42A 3ag4N-3h09A:
undetectable		 3ag4N-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.39A 3asnA-3h09A:
undetectable		 3asnA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.43A 3asnN-3h09A:
undetectable		 3asnN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.39A 3asoA-3h09A:
undetectable		 3asoA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.41A 3asoN-3h09A:
undetectable		 3asoN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_3
(PHOSPHOLIPASE A2)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 5 VAL A 737
VAL A 736
THR A 802
THR A 712
 None
 1.27A 3bjwG-3h09A:
undetectable		 3bjwG-3h09A:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 5 VAL A 737
VAL A 736
THR A 802
THR A 712
 None
 1.30A 3bjwD-3h09A:
undetectable		 3bjwD-3h09A:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.69A 3bvdA-3h09A:
undetectable		 3bvdA-3h09A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 8 HIS A 109
GLY A 115
ASN A 116
PHE A 136
 None
 1.25A 3ccfA-3h09A:
undetectable		 3ccfA-3h09A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 9 PHE A 110
VAL A  82
GLY A 115
ARG A 134
GLY A 111
 None
 1.38A 3csjB-3h09A:
undetectable		 3csjB-3h09A:
12.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.48A 3dtuA-3h09A:
undetectable		 3dtuA-3h09A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.45A 3dtuC-3h09A:
undetectable		 3dtuC-3h09A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 7 ILE A  72
PHE A  77
PHE A 293
GLY A 300
 None
 0.89A 3em0B-3h09A:
undetectable		 3em0B-3h09A:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 879
HIS A 861
HIS A 859
 None
 0.69A 3hiiA-3h09A:
undetectable		 3hiiA-3h09A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 879
HIS A 861
HIS A 859
 None
 0.69A 3hiiB-3h09A:
undetectable		 3hiiB-3h09A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J7Z_A_ERYA9000_0
(23S RRNA
50S RIBOSOMAL
PROTEIN L22
ERMCL NASCENT CHAIN)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 LYS A 726
ILE A 211
PHE A 210
 None
 0.99A 3j7zS-3h09A:
undetectable
3j7za-3h09A:
undetectable		 3j7zS-3h09A:
9.02
3j7za-3h09A:
2.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_1
(FIV PROTEASE)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 10 LEU A 452
ILE A 499
VAL A 497
ILE A 461
LEU A 472
 None
 1.00A 3ogqA-3h09A:
undetectable		 3ogqA-3h09A:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_B_KKKB413_1
(FLAVOHEMOGLOBIN)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 12 TYR A 314
ALA A 238
HIS A 100
LEU A 222
GLY A 205
 None
None
ACT  A1900 (-4.1A)
None
None
 1.12A 3ozwB-3h09A:
undetectable		 3ozwB-3h09A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_C_ACHC323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 8 GLU A 176
TYR A 135
LEU A 170
PHE A 110
 None
 1.00A 3rqwC-3h09A:
undetectable
3rqwD-3h09A:
undetectable		 3rqwC-3h09A:
14.18
3rqwD-3h09A:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 8 GLU A 176
TYR A 135
LEU A 170
PHE A 110
 None
 1.00A 3rqwI-3h09A:
undetectable
3rqwJ-3h09A:
undetectable		 3rqwI-3h09A:
14.18
3rqwJ-3h09A:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_J_ACHJ323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 8 GLU A 176
TYR A 135
LEU A 170
PHE A 110
 None
 1.00A 3rqwF-3h09A:
undetectable
3rqwJ-3h09A:
undetectable		 3rqwF-3h09A:
14.18
3rqwJ-3h09A:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S33_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.60A 3s33A-3h09A:
undetectable		 3s33A-3h09A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.68A 3s38A-3h09A:
undetectable		 3s38A-3h09A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S39_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.58A 3s39A-3h09A:
undetectable		 3s39A-3h09A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.66A 3s3aA-3h09A:
undetectable		 3s3aA-3h09A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3B_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.59A 3s3bA-3h09A:
undetectable		 3s3bA-3h09A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3C_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.64A 3s3cA-3h09A:
undetectable		 3s3cA-3h09A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3D_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.59A 3s3dA-3h09A:
undetectable		 3s3dA-3h09A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SGL_A_SAMA692_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 12 GLY A 679
GLY A 703
THR A 704
LEU A 705
GLY A 564
 None
 0.99A 3sglA-3h09A:
undetectable		 3sglA-3h09A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 12 LEU A 371
LEU A 399
GLY A 409
GLN A 405
PHE A 412
 None
 1.17A 3tbgC-3h09A:
undetectable		 3tbgC-3h09A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_2
(ADENOSINE KINASE,
PUTATIVE)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 5 LEU A 279
ALA A 244
MET A  74
ASN A  43
 None
 1.50A 3uq6A-3h09A:
undetectable		 3uq6A-3h09A:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 12 PRO A  92
GLY A 456
SER A 504
VAL A 479
LEU A 472
 None
 1.20A 3v8vA-3h09A:
undetectable		 3v8vA-3h09A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_B_SAMB801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 11 GLY A 458
SER A 504
ASP A 476
VAL A 506
LEU A 472
 None
 1.18A 3v8vB-3h09A:
undetectable		 3v8vB-3h09A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 12 GLY A 429
GLY A 408
ASN A 383
PHE A 173
LEU A 452
 None
 1.19A 3vywA-3h09A:
undetectable		 3vywA-3h09A:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 12 GLY A 429
GLY A 408
ASN A 383
PHE A 173
LEU A 452
 None
 1.16A 3vywB-3h09A:
undetectable		 3vywB-3h09A:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_0
(MNMC2)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 12 GLY A 429
GLY A 386
ASN A 383
PHE A 173
LEU A 452
 None
 1.14A 3vywC-3h09A:
undetectable		 3vywC-3h09A:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 12 GLY A 429
GLY A 408
ASN A 383
PHE A 173
LEU A 452
 None
 1.18A 3vywD-3h09A:
undetectable		 3vywD-3h09A:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 12 LEU A 827
ILE A 783
VAL A 781
LEU A 760
VAL A 700
 None
 1.02A 3w68A-3h09A:
undetectable		 3w68A-3h09A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 12 LEU A 827
ILE A 783
VAL A 781
LEU A 760
VAL A 700
 None
 1.06A 3w68D-3h09A:
undetectable		 3w68D-3h09A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.45A 3wg7A-3h09A:
undetectable		 3wg7A-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.47A 3wg7N-3h09A:
undetectable		 3wg7N-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.45A 3x2qA-3h09A:
undetectable		 3x2qA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.44A 3x2qN-3h09A:
undetectable		 3x2qN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 7 ASN A 872
LEU A 900
GLY A 876
SER A 905
 None
 0.82A 4cp3A-3h09A:
undetectable
4cp3B-3h09A:
undetectable		 4cp3A-3h09A:
8.97
4cp3B-3h09A:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA302_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 5 HIS A 100
TYR A 239
GLY A 286
SER A 288
 ACT  A1900 (-4.1A)
None
ACT  A1900 (-3.5A)
ACT  A1900 (-2.6A)
 1.13A 4fu8A-3h09A:
12.2		 4fu8A-3h09A:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 12 VAL A 852
GLY A 842
GLY A 864
ILE A 844
LEU A 835
 None
 1.01A 4iv0A-3h09A:
undetectable		 4iv0A-3h09A:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7A_A_MXDA1002_1
(ANDROGEN RECEPTOR)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 GLU A 321
TRP A 319
LYS A 160
 None
 1.44A 4k7aA-3h09A:
undetectable		 4k7aA-3h09A:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 8 THR A 689
LEU A 687
VAL A 801
VAL A 737
 None
 1.10A 4l4eA-3h09A:
undetectable		 4l4eA-3h09A:
16.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 12 VAL A 852
GLY A 842
GLY A 864
ILE A 844
LEU A 835
 None
 1.05A 4mwzB-3h09A:
undetectable		 4mwzB-3h09A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_C_377C401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 6 GLU A 176
TYR A 135
LEU A 170
PHE A 110
 None
 1.09A 4twdB-3h09A:
undetectable
4twdC-3h09A:
undetectable		 4twdB-3h09A:
13.55
4twdC-3h09A:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_E_377E401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 6 GLU A 176
TYR A 135
LEU A 170
PHE A 110
 None
 1.05A 4twdD-3h09A:
undetectable
4twdE-3h09A:
undetectable		 4twdD-3h09A:
13.55
4twdE-3h09A:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 7 GLU A 176
TYR A 135
LEU A 170
PHE A 110
 None
 1.09A 4twdF-3h09A:
undetectable
4twdJ-3h09A:
undetectable		 4twdF-3h09A:
13.55
4twdJ-3h09A:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 6 GLU A 176
TYR A 135
LEU A 170
PHE A 110
 None
 1.08A 4twdF-3h09A:
undetectable
4twdG-3h09A:
undetectable		 4twdF-3h09A:
13.55
4twdG-3h09A:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_J_377J401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 6 GLU A 176
TYR A 135
LEU A 170
PHE A 110
 None
 1.11A 4twdI-3h09A:
undetectable
4twdJ-3h09A:
undetectable		 4twdI-3h09A:
13.55
4twdJ-3h09A:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.43A 5b1aA-3h09A:
undetectable		 5b1aA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.47A 5b1aN-3h09A:
undetectable		 5b1aN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.43A 5b1bA-3h09A:
undetectable		 5b1bA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.47A 5b1bN-3h09A:
undetectable		 5b1bN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.42A 5b3sA-3h09A:
undetectable		 5b3sA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.47A 5b3sN-3h09A:
undetectable		 5b3sN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_C_MMZC503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 4 TYR A 520
ASN A 133
SER A 130
SER A 129
 None
 1.32A 5gsnC-3h09A:
0.0		 5gsnC-3h09A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 12 VAL A 138
ARG A 169
LEU A 371
LEU A 410
GLY A 409
 None
 1.35A 5iktB-3h09A:
undetectable		 5iktB-3h09A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.46A 5iy5A-3h09A:
undetectable		 5iy5A-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.43A 5iy5N-3h09A:
undetectable		 5iy5N-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 LYS A 438
ASP A 436
ILE A 461
 None
 0.76A 5kc4E-3h09A:
undetectable		 5kc4E-3h09A:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 6 ARG A 169
ASN A 141
ASN A  91
GLN A  93
 None
 1.15A 5l6eA-3h09A:
undetectable		 5l6eA-3h09A:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MTH_B_ACTB302_0
(ANTIBODY FAB HEAVY
CHAIN
ANTIBODY FAB LIGHT
CHAIN)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 5 TYR A 282
TYR A 308
TYR A 248
ARG A 203
 None
 1.30A 5mthA-3h09A:
1.4
5mthB-3h09A:
0.6		 5mthA-3h09A:
13.32
5mthB-3h09A:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 12 LEU A 827
ILE A 783
VAL A 781
LEU A 760
VAL A 700
 None
 1.02A 5mugA-3h09A:
undetectable		 5mugA-3h09A:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 12 ALA A 407
GLY A 408
SER A 388
LYS A 387
ASN A 402
 None
 1.22A 5nwuA-3h09A:
undetectable		 5nwuA-3h09A:
3.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA608_0
(ACETYLCHOLINESTERASE)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 7 ASP A 936
THR A 910
LEU A 912
THR A 938
 None
 1.07A 5ov9A-3h09A:
undetectable		 5ov9A-3h09A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 6 PRO A 353
VAL A 369
VAL A 389
ILE A 403
 MLA  A2100 (-3.9A)
None
None
None
 0.84A 5pbeA-3h09A:
undetectable		 5pbeA-3h09A:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.43A 5w97a-3h09A:
undetectable		 5w97a-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.43A 5waua-3h09A:
undetectable		 5waua-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.46A 5x19A-3h09A:
undetectable		 5x19A-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.49A 5x19N-3h09A:
undetectable		 5x19N-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.55A 5x1bA-3h09A:
undetectable		 5x1bA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.47A 5x1bN-3h09A:
undetectable		 5x1bN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.50A 5x1fA-3h09A:
undetectable		 5x1fA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.46A 5x1fN-3h09A:
undetectable		 5x1fN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 8 ARG A 745
GLY A 657
PHE A 658
TYR A 800
 None
ACT  A1800 ( 4.5A)
None
None
 0.78A 5x5qF-3h09A:
undetectable		 5x5qF-3h09A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.46A 5xdqA-3h09A:
undetectable		 5xdqA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.46A 5xdqN-3h09A:
undetectable		 5xdqN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.43A 5xdxA-3h09A:
undetectable		 5xdxA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.43A 5xdxN-3h09A:
undetectable		 5xdxN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.46A 5z84A-3h09A:
undetectable		 5z84A-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.51A 5z84N-3h09A:
undetectable		 5z84N-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.46A 5z85A-3h09A:
undetectable		 5z85A-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.50A 5z85N-3h09A:
undetectable		 5z85N-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.42A 5z86A-3h09A:
undetectable		 5z86A-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.49A 5z86N-3h09A:
undetectable		 5z86N-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.43A 5zcoA-3h09A:
undetectable		 5zcoA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.46A 5zcoN-3h09A:
undetectable		 5zcoN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.43A 5zcpA-3h09A:
undetectable		 5zcpA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.49A 5zcpN-3h09A:
undetectable		 5zcpN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.44A 5zcqA-3h09A:
undetectable		 5zcqA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.46A 5zcqN-3h09A:
undetectable		 5zcqN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_A_TLFA300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 12 VAL A 868
ILE A 783
VAL A 821
VAL A 852
PHE A 833
 None
 1.24A 6ap6A-3h09A:
undetectable		 6ap6A-3h09A:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_B_TLFB300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 12 VAL A 868
ILE A 783
VAL A 821
VAL A 852
PHE A 833
 None
 1.24A 6ap6B-3h09A:
undetectable		 6ap6B-3h09A:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 TYR A 606
ASN A 578
LEU A 603
 None
 0.81A 6b58A-3h09A:
undetectable		 6b58A-3h09A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		5 / 12 PHE A 841
LEU A 871
VAL A 852
THR A 843
GLY A 842
 None
 1.22A 6brdA-3h09A:
undetectable		 6brdA-3h09A:
5.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		4 / 6 ALA A 493
LEU A 528
SER A 518
ASN A 533
 None
 0.96A 6f88B-3h09A:
undetectable		 6f88B-3h09A:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.73A 6giqa-3h09A:
undetectable		 6giqa-3h09A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.45A 6hu9a-3h09A:
undetectable		 6hu9a-3h09A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.54A 6hu9m-3h09A:
undetectable		 6hu9m-3h09A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.48A 6nknA-3h09A:
undetectable		 6nknA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.45A 6nknN-3h09A:
undetectable		 6nknN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.48A 6nmfA-3h09A:
undetectable		 6nmfA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.45A 6nmfN-3h09A:
undetectable		 6nmfN-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.50A 6nmpA-3h09A:
undetectable		 6nmpA-3h09A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h09 IMMUNOGLOBULIN A1
PROTEASE
(Haemophilus
influenzae) 		3 / 3 HIS A 859
HIS A 879
HIS A 861
 None
 0.44A 6nmpN-3h09A:
undetectable		 6nmpN-3h09A:
19.62