SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h0d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BU8_A_TF4A1379_1
(PYRUVATE
DEHYDROGENASE KINASE
ISOENZYME 2)		 3h0d CTSR
(Geobacillus
stearothermophil
us) 		4 / 8 LEU A  12
ILE A  42
ILE A  70
ILE A  68
 None
 0.80A 2bu8A-3h0dA:
undetectable		 2bu8A-3h0dA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 3h0d CTSR
(Geobacillus
stearothermophil
us) 		4 / 7 SER A  96
ASP A 100
SER A  97
SER A  94
 None
 1.12A 2cmlA-3h0dA:
undetectable		 2cmlA-3h0dA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3h0d CTSR
(Geobacillus
stearothermophil
us) 		3 / 3 MET A 123
GLN A  95
ARG A 135
 None
None
PO4  A 157 (-3.9A)
 1.09A 5ewzB-3h0dA:
3.1		 5ewzB-3h0dA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3h0d CTSR
(Geobacillus
stearothermophil
us) 		3 / 3 MET A 123
GLN A  95
ARG A 135
 None
None
PO4  A 157 (-3.9A)
 1.06A 5m35B-3h0dA:
3.1		 5m35B-3h0dA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3h0d CTSR
(Geobacillus
stearothermophil
us) 		3 / 3 MET A 123
GLN A  95
ARG A 135
 None
None
PO4  A 157 (-3.9A)
 1.04A 5m36A-3h0dA:
2.3		 5m36A-3h0dA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3h0d CTSR
(Geobacillus
stearothermophil
us) 		3 / 3 MET A 123
GLN A  95
ARG A 135
 None
None
PO4  A 157 (-3.9A)
 1.08A 6fn9A-3h0dA:
undetectable		 6fn9A-3h0dA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3h0d CTSR
(Geobacillus
stearothermophil
us) 		3 / 3 MET A 123
GLN A  95
ARG A 135
 None
None
PO4  A 157 (-3.9A)
 1.10A 6fnaB-3h0dA:
3.0		 6fnaB-3h0dA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3h0d CTSR
(Geobacillus
stearothermophil
us) 		3 / 3 MET A 123
GLN A  95
ARG A 135
 None
None
PO4  A 157 (-3.9A)
 1.07A 6fnbA-3h0dA:
2.9		 6fnbA-3h0dA:
24.22