SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h0k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_2
(CARBONIC ANHYDRASE
II)		 3h0k UPF0200 PROTEIN
SSO1041
(Sulfolobus
solfataricus) 		4 / 4 HIS A  85
VAL A  88
THR A  82
LEU A 105
 None
 1.39A 1oq5A-3h0kA:
undetectable		 1oq5A-3h0kA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_H_FUAH709_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3h0k UPF0200 PROTEIN
SSO1041
(Sulfolobus
solfataricus) 		6 / 12 LEU A 106
VAL A  77
PHE A  90
VAL A  10
VAL A  72
ALA A  73
 None
 1.44A 1q23H-3h0kA:
undetectable
1q23I-3h0kA:
undetectable		 1q23H-3h0kA:
18.64
1q23I-3h0kA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_1
(PROTEASE)		 3h0k UPF0200 PROTEIN
SSO1041
(Sulfolobus
solfataricus) 		5 / 12 LEU A  80
ASP A  40
GLY A  92
VAL A  93
ILE A  36
 None
 1.25A 2o4lA-3h0kA:
undetectable		 2o4lA-3h0kA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 3h0k UPF0200 PROTEIN
SSO1041
(Sulfolobus
solfataricus) 		6 / 9 LEU A  80
ASP A  40
GLY A  92
VAL A  93
VAL A  88
ILE A  36
 None
 1.16A 3oxvA-3h0kA:
undetectable		 3oxvA-3h0kA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_2
(HIV-1 PROTEASE)		 3h0k UPF0200 PROTEIN
SSO1041
(Sulfolobus
solfataricus) 		6 / 10 LEU A  80
ASP A  40
GLY A  92
VAL A  93
VAL A  88
ILE A  36
 None
 1.32A 3oxwD-3h0kA:
undetectable		 3oxwD-3h0kA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 3h0k UPF0200 PROTEIN
SSO1041
(Sulfolobus
solfataricus) 		5 / 12 VAL A 180
LEU A  96
VAL A  99
GLY A  15
MET A  38
 None
 1.35A 6brdA-3h0kA:
undetectable		 6brdA-3h0kA:
19.44