SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h0o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3h0o BETA-GLUCANASE
(Fibrobacter
succinogenes) 		3 / 3 ASN A 139
TRP A 141
GLN A 161
 TRS  A 404 (-3.3A)
TRS  A 404 (-3.9A)
None
 0.73A 1xoqA-3h0oA:
undetectable		 1xoqA-3h0oA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KUH_A_HLTA150_1
(CALMODULIN)		 3h0o BETA-GLUCANASE
(Fibrobacter
succinogenes) 		4 / 6 LEU A 103
MET A  39
LEU A 136
GLU A  24
 None
 1.18A 2kuhA-3h0oA:
undetectable		 2kuhA-3h0oA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1501_1
(CYTOCHROME P450 3A4)		 3h0o BETA-GLUCANASE
(Fibrobacter
succinogenes) 		5 / 10 PHE A 182
ILE A  73
PHE A  23
THR A 113
GLY A  21
 None
 1.32A 2v0mA-3h0oA:
undetectable		 2v0mA-3h0oA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA91_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3h0o BETA-GLUCANASE
(Fibrobacter
succinogenes) 		3 / 3 PHE A 162
GLN A  96
PHE A 236
 None
 0.74A 3rv5A-3h0oA:
undetectable		 3rv5A-3h0oA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 3h0o BETA-GLUCANASE
(Fibrobacter
succinogenes) 		4 / 7 PHE A 152
ALA A  32
THR A  35
LEU A 228
 None
 0.98A 3t3sC-3h0oA:
undetectable		 3t3sC-3h0oA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 3h0o BETA-GLUCANASE
(Fibrobacter
succinogenes) 		3 / 3 TRP A 198
TRP A 186
THR A 187
 None
 1.35A 4bboB-3h0oA:
undetectable		 4bboB-3h0oA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 3h0o BETA-GLUCANASE
(Fibrobacter
succinogenes) 		4 / 7 ILE A 163
LEU A  12
PHE A 193
GLY A 195
 None
None
ACT  A 405 (-4.5A)
None
 1.06A 4hc3A-3h0oA:
undetectable		 4hc3A-3h0oA:
16.23