SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h0x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_2
(HMG-COA REDUCTASE)		 3h0x 78 KDA
GLUCOSE-REGULATED
PROTEIN HOMOLOG
(Saccharomyces
cerevisiae) 		4 / 8 GLU A 556
LEU A 553
ALA A 441
LEU A 442
 None
 0.92A 1hwiD-3h0xA:
undetectable		 1hwiD-3h0xA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 3h0x 78 KDA
GLUCOSE-REGULATED
PROTEIN HOMOLOG
(Saccharomyces
cerevisiae) 		6 / 12 LEU A 504
ASP A 535
GLY A 537
ILE A 470
VAL A 481
ILE A 507
 None
 1.36A 3jw2B-3h0xA:
undetectable		 3jw2B-3h0xA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 3h0x 78 KDA
GLUCOSE-REGULATED
PROTEIN HOMOLOG
(Saccharomyces
cerevisiae) 		6 / 12 LEU A 504
ASP A 535
GLY A 537
ILE A 470
VAL A 481
ILE A 507
 None
 1.36A 4jecA-3h0xA:
undetectable		 4jecA-3h0xA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 3h0x 78 KDA
GLUCOSE-REGULATED
PROTEIN HOMOLOG
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 485
ILE A 446
VAL A 531
ILE A 546
 None
 0.66A 5bmvC-3h0xA:
undetectable		 5bmvC-3h0xA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FDY_U_DB8U302_1
(-)		 3h0x 78 KDA
GLUCOSE-REGULATED
PROTEIN HOMOLOG
(Saccharomyces
cerevisiae) 		5 / 9 PRO A 455
MET A 453
VAL A 485
SER A 468
ILE A 446
 None
 1.37A 6fdyU-3h0xA:
undetectable		 6fdyU-3h0xA:
19.49