SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h1i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVM_A_TMGA501_1
(METHIONINE
AMINOPEPTIDASE)		 3h1i CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
(Gallus
gallus) 		4 / 7 CYH E 158
TYR E 157
TYR E 165
CYH E 139
 FES  E 501 (-2.2A)
None
None
FES  E 501 (-2.2A)
 1.27A 1yvmA-3h1iE:
undetectable		 1yvmA-3h1iE:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_B_CHDB1086_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 3h1i CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
(Gallus
gallus) 		5 / 10 GLN E 108
GLU E 105
ARG E 172
PHE E 153
GLY E 151
 None
 1.34A 2eikA-3h1iE:
undetectable
2eikB-3h1iE:
0.0
2eikT-3h1iE:
0.0		 2eikA-3h1iE:
15.86
2eikB-3h1iE:
21.37
2eikT-3h1iE:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_B_CHDB1086_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 3h1i CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
(Gallus
gallus) 		5 / 10 GLN E 108
GLU E 105
ARG E 172
PHE E 153
GLY E 151
 None
 1.36A 2eimA-3h1iE:
0.3
2eimB-3h1iE:
0.5
2eimT-3h1iE:
0.0		 2eimA-3h1iE:
15.86
2eimB-3h1iE:
21.37
2eimT-3h1iE:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3h1i CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
(Gallus
gallus) 		5 / 12 TYR E 185
ILE E  76
LEU E  78
VAL E 127
PHE E  89
 None
 1.28A 2qo6A-3h1iE:
undetectable		 2qo6A-3h1iE:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA500_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 3h1i CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
(Gallus
gallus) 		4 / 4 ALA E 176
HIS E 141
HIS E 161
PRO E 175
 None
FES  E 501 (-3.1A)
FES  E 501 ( 3.1A)
None
 1.32A 3mbgA-3h1iE:
undetectable		 3mbgA-3h1iE:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC900_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 3h1i CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
(Gallus
gallus) 		4 / 4 ALA E 176
HIS E 141
HIS E 161
PRO E 175
 None
FES  E 501 (-3.1A)
FES  E 501 ( 3.1A)
None
 1.32A 3mbgC-3h1iE:
undetectable		 3mbgC-3h1iE:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 3h1i CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
(Gallus
gallus) 		3 / 3 PRO E 183
TYR E 185
GLY E 196
 None
 0.69A 4g2zA-3h1iE:
undetectable		 4g2zA-3h1iE:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3h1i CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
(Gallus
gallus) 		3 / 3 THR E 140
HIS E 122
LEU E 117
 None
 0.80A 5axdA-3h1iE:
undetectable		 5axdA-3h1iE:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3h1i CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
(Gallus
gallus) 		3 / 3 THR E 140
HIS E 122
LEU E 117
 None
 0.80A 5axdC-3h1iE:
undetectable		 5axdC-3h1iE:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 3h1i CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
(Gallus
gallus) 		5 / 10 GLY E 155
TYR E 156
GLY E 169
SER E 168
ARG E 101
 None
 1.42A 5hwkB-3h1iE:
undetectable		 5hwkB-3h1iE:
23.89