SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h1n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3h1n PROBABLE GLUTATHIONE
S-TRANSFERASE
(Bordetella
bronchiseptica) 		5 / 12 ILE A  11
GLY A  10
TYR A 210
LEU A   5
TYR A  29
 None
 1.46A 1fm6X-3h1nA:
undetectable		 1fm6X-3h1nA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3h1n PROBABLE GLUTATHIONE
S-TRANSFERASE
(Bordetella
bronchiseptica) 		4 / 5 PRO A  56
ILE A 223
GLY A  13
TYR A   7
 None
CL  A 234 (-4.2A)
CL  A 234 (-3.6A)
None
 1.08A 2jkjD-3h1nA:
undetectable		 2jkjD-3h1nA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3h1n PROBABLE GLUTATHIONE
S-TRANSFERASE
(Bordetella
bronchiseptica) 		4 / 5 PRO A  56
ILE A 223
GLY A  13
TYR A   7
 None
CL  A 234 (-4.2A)
CL  A 234 (-3.6A)
None
 1.09A 2jkjF-3h1nA:
undetectable		 2jkjF-3h1nA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3h1n PROBABLE GLUTATHIONE
S-TRANSFERASE
(Bordetella
bronchiseptica) 		4 / 8 TYR A   7
ILE A  11
GLY A  13
ARG A  14
 None
None
CL  A 234 (-3.6A)
None
 0.81A 2vctA-3h1nA:
20.8		 2vctA-3h1nA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3h1n PROBABLE GLUTATHIONE
S-TRANSFERASE
(Bordetella
bronchiseptica) 		4 / 8 TYR A   7
ILE A  11
GLY A  13
ARG A  14
 None
None
CL  A 234 (-3.6A)
None
 0.79A 2vctB-3h1nA:
20.7		 2vctB-3h1nA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3h1n PROBABLE GLUTATHIONE
S-TRANSFERASE
(Bordetella
bronchiseptica) 		4 / 8 TYR A   7
ILE A  11
GLY A  13
ARG A  14
 None
None
CL  A 234 (-3.6A)
None
 0.78A 2vctC-3h1nA:
4.9		 2vctC-3h1nA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_D_ASDD1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3h1n PROBABLE GLUTATHIONE
S-TRANSFERASE
(Bordetella
bronchiseptica) 		4 / 7 TYR A   7
ILE A  11
GLY A  13
ARG A  14
 None
None
CL  A 234 (-3.6A)
None
 0.75A 2vctD-3h1nA:
20.6		 2vctD-3h1nA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3h1n PROBABLE GLUTATHIONE
S-TRANSFERASE
(Bordetella
bronchiseptica) 		4 / 8 LEU A  72
GLN A  96
SER A 168
HIS A 171
 None
 1.01A 3kp2A-3h1nA:
undetectable
3kp2B-3h1nA:
undetectable		 3kp2A-3h1nA:
20.00
3kp2B-3h1nA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 3h1n PROBABLE GLUTATHIONE
S-TRANSFERASE
(Bordetella
bronchiseptica) 		4 / 8 GLU A  23
PHE A  -2
GLN A  -1
ARG A 215
 None
None
None
EDO  A 236 (-2.9A)
 0.99A 3mjrD-3h1nA:
undetectable		 3mjrD-3h1nA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_D_T44D328_1
(5-HYDROXYISOURATE
HYDROLASE)		 3h1n PROBABLE GLUTATHIONE
S-TRANSFERASE
(Bordetella
bronchiseptica) 		5 / 9 LEU A   5
PRO A  56
LEU A  58
THR A  68
LEU A  72
 None
 1.15A 3q1eB-3h1nA:
undetectable
3q1eD-3h1nA:
undetectable		 3q1eB-3h1nA:
16.67
3q1eD-3h1nA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA91_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3h1n PROBABLE GLUTATHIONE
S-TRANSFERASE
(Bordetella
bronchiseptica) 		3 / 3 PHE A  17
GLN A  67
PHE A 224
 None
 0.56A 3rv5A-3h1nA:
undetectable		 3rv5A-3h1nA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_2
(POL POLYPROTEIN)		 3h1n PROBABLE GLUTATHIONE
S-TRANSFERASE
(Bordetella
bronchiseptica) 		5 / 9 ARG A  45
ALA A  33
ASP A   9
GLY A  37
LEU A  41
 None
 1.15A 3u7sB-3h1nA:
undetectable		 3u7sB-3h1nA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_A_BRLA501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3h1n PROBABLE GLUTATHIONE
S-TRANSFERASE
(Bordetella
bronchiseptica) 		4 / 5 GLY A  13
LEU A  72
LEU A   5
LEU A 211
 CL  A 234 (-3.6A)
None
None
None
 0.86A 4o8fA-3h1nA:
undetectable		 4o8fA-3h1nA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_1
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 3h1n PROBABLE GLUTATHIONE
S-TRANSFERASE
(Bordetella
bronchiseptica) 		5 / 12 GLY A 222
PHE A 133
LEU A 102
ARG A  14
PHE A 224
 CL  A 234 ( 3.9A)
None
None
None
None
 1.29A 5nknA-3h1nA:
undetectable		 5nknA-3h1nA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 3h1n PROBABLE GLUTATHIONE
S-TRANSFERASE
(Bordetella
bronchiseptica) 		5 / 12 ILE A  71
TYR A  57
ALA A  33
LEU A  22
ASP A  31
 None
 1.29A 6ie8A-3h1nA:
undetectable		 6ie8A-3h1nA:
20.78