SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h1q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 147
THR A 166
PRO A 165
 None
 0.81A 1a7yA-3h1qA:
undetectable		 1a7yA-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 166
PRO A 165
THR A 147
 None
 0.85A 1a7yB-3h1qA:
undetectable		 1a7yB-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 147
THR A 166
PRO A 165
 None
 0.75A 1a7yB-3h1qA:
undetectable		 1a7yB-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 147
THR A 166
PRO A 165
 None
 0.80A 1dscC-3h1qA:
undetectable		 1dscC-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 147
THR A 166
PRO A 165
 None
 0.86A 1fjaC-3h1qA:
undetectable		 1fjaC-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 147
THR A 166
PRO A 165
 None
 0.86A 1fjaD-3h1qA:
undetectable		 1fjaD-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 166
PRO A 165
THR A 147
 None
 0.83A 1i3wE-3h1qA:
undetectable		 1i3wE-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 147
THR A 166
PRO A 165
 None
 0.82A 1i3wE-3h1qA:
undetectable		 1i3wE-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 147
THR A 166
PRO A 165
 None
 0.83A 1i3wF-3h1qA:
undetectable		 1i3wF-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 166
PRO A 165
THR A 147
 None
 0.80A 1i3wG-3h1qA:
undetectable		 1i3wG-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 147
THR A 166
PRO A 165
 None
 0.78A 1i3wG-3h1qA:
undetectable		 1i3wG-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 147
THR A 166
PRO A 165
 None
 0.81A 1i3wH-3h1qA:
undetectable		 1i3wH-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		4 / 8 ASP A  36
ILE A 265
GLY A 264
GLY A 231
 ATP  A 301 (-2.5A)
None
None
ATP  A 301 (-3.5A)
 0.58A 1me7A-3h1qA:
undetectable		 1me7A-3h1qA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 166
PRO A 165
THR A 147
 None
 0.82A 1mnvD-3h1qA:
undetectable		 1mnvD-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 147
THR A 166
PRO A 165
 None
 0.83A 1qfiA-3h1qA:
undetectable		 1qfiA-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 147
THR A 166
PRO A 165
 None
 0.77A 1qfiB-3h1qA:
undetectable		 1qfiB-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		4 / 8 ALA A  95
LEU A  32
GLY A  33
GLY A  62
 None
None
ATP  A 301 ( 3.8A)
None
 0.86A 1rukH-3h1qA:
undetectable
1rukL-3h1qA:
undetectable		 1rukH-3h1qA:
21.13
1rukL-3h1qA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		5 / 12 LEU A 258
ILE A 265
THR A  94
ILE A  14
LEU A  10
 ATP  A 301 (-3.8A)
None
None
None
None
 1.14A 1tw4B-3h1qA:
undetectable		 1tw4B-3h1qA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 166
PRO A 165
THR A 147
 None
 0.81A 1unjF-3h1qA:
undetectable		 1unjF-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 147
THR A 166
PRO A 165
 None
 0.82A 1unjF-3h1qA:
undetectable		 1unjF-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 166
PRO A 165
THR A 147
 None
 0.85A 1unjL-3h1qA:
undetectable		 1unjL-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 147
THR A 166
PRO A 165
 None
 0.83A 1unjL-3h1qA:
undetectable		 1unjL-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 166
PRO A 165
THR A 147
 None
 0.84A 1unjR-3h1qA:
undetectable		 1unjR-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 147
THR A 166
PRO A 165
 None
 0.83A 1unjR-3h1qA:
undetectable		 1unjR-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 147
THR A 166
PRO A 165
 None
 0.82A 1unjW-3h1qA:
undetectable		 1unjW-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 166
PRO A 165
THR A 147
 None
 0.83A 1unjX-3h1qA:
undetectable		 1unjX-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 147
THR A 166
PRO A 165
 None
 0.82A 1unjX-3h1qA:
undetectable		 1unjX-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 166
PRO A 165
THR A 147
 None
 0.83A 1unmE-3h1qA:
undetectable		 1unmE-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 147
THR A 166
PRO A 165
 None
 0.81A 1unmE-3h1qA:
undetectable		 1unmE-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 166
PRO A 165
THR A 147
 None
 0.79A 1unmF-3h1qA:
undetectable		 1unmF-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 147
THR A 166
PRO A 165
 None
 0.76A 1unmF-3h1qA:
undetectable		 1unmF-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 147
THR A 166
PRO A 165
 None
 0.76A 209dC-3h1qA:
undetectable		 209dC-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_A_GBNA502_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		4 / 8 GLY A 232
THR A 233
ALA A 234
VAL A 140
 ATP  A 301 (-3.1A)
ATP  A 301 (-4.7A)
None
None
 0.83A 2a1hA-3h1qA:
undetectable
2a1hB-3h1qA:
undetectable		 2a1hA-3h1qA:
21.84
2a1hB-3h1qA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_B_GBNB501_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		4 / 8 VAL A 140
GLY A 232
THR A 233
ALA A 234
 None
ATP  A 301 (-3.1A)
ATP  A 301 (-4.7A)
None
 0.87A 2a1hA-3h1qA:
undetectable
2a1hB-3h1qA:
undetectable		 2a1hA-3h1qA:
21.84
2a1hB-3h1qA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		5 / 12 GLY A 167
GLY A 149
GLY A 144
ILE A 139
VAL A 214
 None
None
ATP  A 301 (-3.1A)
None
None
 0.98A 2oxtA-3h1qA:
undetectable		 2oxtA-3h1qA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		4 / 6 PHE A 243
PHE A 239
GLY A 167
GLY A 168
 None
None
None
ATP  A 301 (-3.4A)
 1.00A 2qr2A-3h1qA:
undetectable
2qr2B-3h1qA:
undetectable		 2qr2A-3h1qA:
20.98
2qr2B-3h1qA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		4 / 5 GLY A 167
GLY A 168
PHE A 243
PHE A 239
 None
ATP  A 301 (-3.4A)
None
None
 0.94A 2qr2A-3h1qA:
undetectable
2qr2B-3h1qA:
undetectable		 2qr2A-3h1qA:
20.98
2qr2B-3h1qA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		4 / 8 PHE A 243
ILE A 207
GLY A 167
GLY A 168
 None
None
None
ATP  A 301 (-3.4A)
 0.75A 2qx4A-3h1qA:
undetectable
2qx4B-3h1qA:
undetectable		 2qx4A-3h1qA:
20.98
2qx4B-3h1qA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		4 / 6 PHE A 243
ILE A 207
GLY A 167
GLY A 168
 None
None
None
ATP  A 301 (-3.4A)
 0.75A 2qx6A-3h1qA:
undetectable
2qx6B-3h1qA:
undetectable		 2qx6A-3h1qA:
20.98
2qx6B-3h1qA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1501_1
(CYTOCHROME P450 3A4)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		5 / 10 ASP A  31
ILE A 150
LEU A 259
ILE A 213
GLY A 145
 ATP  A 301 (-3.7A)
None
None
None
ATP  A 301 (-3.7A)
 1.15A 2v0mA-3h1qA:
undetectable		 2v0mA-3h1qA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		4 / 8 HIS A 256
ASN A   8
ASP A  12
ARG A  16
 None
 1.09A 2v57A-3h1qA:
undetectable		 2v57A-3h1qA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_C_PRLC1187_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		4 / 8 HIS A 256
ASN A   8
ASP A  12
ARG A  16
 None
 1.09A 2v57C-3h1qA:
undetectable		 2v57C-3h1qA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		4 / 7 PRO A 262
PRO A 257
GLY A 231
LEU A  53
 None
None
ATP  A 301 (-3.5A)
None
 0.94A 2vl2B-3h1qA:
undetectable		 2vl2B-3h1qA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 166
PRO A 165
THR A 147
 None
 0.89A 316dC-3h1qA:
undetectable		 316dC-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_B_FLPB701_1
(CYCLOOXYGENASE-2)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		5 / 11 VAL A  30
LEU A  39
LEU A  32
GLY A 116
ALA A 115
 None
 1.12A 3pghB-3h1qA:
undetectable		 3pghB-3h1qA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		4 / 8 LEU A 171
GLY A 167
THR A 148
VAL A 229
 None
 0.87A 4c9nA-3h1qA:
undetectable		 4c9nA-3h1qA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		4 / 6 TRP A  55
ASN A  11
TYR A 235
LEU A 258
 None
None
ATP  A 301 (-4.3A)
ATP  A 301 (-3.8A)
 1.37A 4f8yA-3h1qA:
undetectable
4f8yB-3h1qA:
undetectable		 4f8yA-3h1qA:
20.22
4f8yB-3h1qA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		3 / 3 THR A 166
PRO A 165
THR A 147
 None
 0.87A 4hivD-3h1qA:
undetectable		 4hivD-3h1qA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		4 / 8 THR A  94
THR A 100
LEU A 122
VAL A  64
 None
 0.94A 4l4eA-3h1qA:
undetectable		 4l4eA-3h1qA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		4 / 8 THR A  94
THR A 100
LEU A 122
VAL A  64
 None
 0.94A 4l4fA-3h1qA:
undetectable		 4l4fA-3h1qA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		5 / 12 TYR A 235
GLY A 232
LEU A   3
GLY A  46
LEU A  10
 ATP  A 301 (-4.3A)
ATP  A 301 (-3.1A)
None
None
None
 0.94A 4ze1A-3h1qA:
undetectable		 4ze1A-3h1qA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_2
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		4 / 4 VAL A 260
LEU A 259
LEU A 258
ASP A  36
 None
None
ATP  A 301 (-3.8A)
ATP  A 301 (-2.5A)
 1.36A 5xv7A-3h1qA:
undetectable		 5xv7A-3h1qA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_B_EY4B500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		4 / 6 GLN A 252
VAL A 253
ALA A 234
THR A 233
 None
None
None
ATP  A 301 (-4.7A)
 0.94A 6cduB-3h1qA:
undetectable
6cduC-3h1qA:
undetectable		 6cduB-3h1qA:
23.91
6cduC-3h1qA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_C_HISC402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		5 / 9 LEU A  89
GLY A  51
LEU A  39
THR A  42
VAL A  49
 None
 1.22A 6czmB-3h1qA:
undetectable
6czmC-3h1qA:
undetectable		 6czmB-3h1qA:
24.86
6czmC-3h1qA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		5 / 9 LEU A  89
GLY A  51
LEU A  39
THR A  42
VAL A  49
 None
 1.21A 6czmD-3h1qA:
undetectable
6czmE-3h1qA:
undetectable		 6czmD-3h1qA:
24.86
6czmE-3h1qA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_F_HISF402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3h1q ETHANOLAMINE
UTILIZATION PROTEIN
EUTJ
(Carboxydothermus
hydrogenoformans) 		5 / 10 LEU A  89
GLY A  51
LEU A  39
THR A  42
VAL A  49
 None
 1.21A 6czmE-3h1qA:
undetectable
6czmF-3h1qA:
undetectable		 6czmE-3h1qA:
24.86
6czmF-3h1qA:
24.86