SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h1s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA2001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 3h1s SUPEROXIDE DISMUTASE
(Francisella
tularensis) 		4 / 6 TRP A 158
GLY A 142
ASN A  66
PRO A 144
 None
 1.23A 1dedA-3h1sA:
undetectable		 1dedA-3h1sA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 3h1s SUPEROXIDE DISMUTASE
(Francisella
tularensis) 		3 / 3 PHE A 190
SER A  89
GLN A  91
 None
 0.75A 3smtA-3h1sA:
undetectable		 3smtA-3h1sA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3h1s SUPEROXIDE DISMUTASE
(Francisella
tularensis) 		4 / 8 GLN A 189
PHE A  76
PHE A  72
TRP A 124
 None
 1.00A 4fgjA-3h1sA:
undetectable
4fgjB-3h1sA:
undetectable		 4fgjA-3h1sA:
23.60
4fgjB-3h1sA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1102_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3h1s SUPEROXIDE DISMUTASE
(Francisella
tularensis) 		4 / 7 TYR A  10
ILE A  24
TYR A  28
HIS A  32
 None
 1.20A 4g5jA-3h1sA:
undetectable		 4g5jA-3h1sA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3h1s SUPEROXIDE DISMUTASE
(Francisella
tularensis) 		4 / 6 TRP A 124
GLN A 189
PHE A  76
PHE A  72
 None
 0.99A 4qogA-3h1sA:
undetectable
4qogB-3h1sA:
undetectable		 4qogA-3h1sA:
23.69
4qogB-3h1sA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3h1s SUPEROXIDE DISMUTASE
(Francisella
tularensis) 		5 / 12 LEU A 145
ILE A  64
HIS A  48
LEU A  42
GLY A  62
 None
 1.09A 5d4uA-3h1sA:
undetectable		 5d4uA-3h1sA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3h1s SUPEROXIDE DISMUTASE
(Francisella
tularensis) 		5 / 12 LEU A 145
ILE A  64
HIS A  48
LEU A  42
GLY A  62
 None
 1.09A 5d4uB-3h1sA:
undetectable		 5d4uB-3h1sA:
22.61