SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h1t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 3h1t TYPE I SITE-SPECIFIC
RESTRICTION-MODIFICA
TION SYSTEM, R
(RESTRICTION)
SUBUNIT
(Vibrio
vulnificus) 		4 / 8 PHE A 533
ALA A 561
ARG A 378
LEU A 523
 None
 1.13A 2bxkA-3h1tA:
undetectable		 2bxkA-3h1tA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3h1t TYPE I SITE-SPECIFIC
RESTRICTION-MODIFICA
TION SYSTEM, R
(RESTRICTION)
SUBUNIT
(Vibrio
vulnificus) 		4 / 5 ALA A 280
ILE A 281
SER A 284
LYS A 322
 None
 1.06A 2othA-3h1tA:
undetectable		 2othA-3h1tA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 3h1t TYPE I SITE-SPECIFIC
RESTRICTION-MODIFICA
TION SYSTEM, R
(RESTRICTION)
SUBUNIT
(Vibrio
vulnificus) 		3 / 3 ARG A 456
ASP A 423
ASN A 461
 None
 0.83A 2zzmA-3h1tA:
4.5		 2zzmA-3h1tA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)		 3h1t TYPE I SITE-SPECIFIC
RESTRICTION-MODIFICA
TION SYSTEM, R
(RESTRICTION)
SUBUNIT
(Vibrio
vulnificus) 		4 / 4 ARG A 457
ASP A 431
GLY A 586
THR A 422
 None
 1.18A 3k4vB-3h1tA:
undetectable		 3k4vB-3h1tA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 3h1t TYPE I SITE-SPECIFIC
RESTRICTION-MODIFICA
TION SYSTEM, R
(RESTRICTION)
SUBUNIT
(Vibrio
vulnificus) 		4 / 8 ASP A 367
ASP A 368
GLN A  73
GLU A  72
 None
 0.99A 3oyaA-3h1tA:
undetectable		 3oyaA-3h1tA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 3h1t TYPE I SITE-SPECIFIC
RESTRICTION-MODIFICA
TION SYSTEM, R
(RESTRICTION)
SUBUNIT
(Vibrio
vulnificus) 		5 / 9 TYR A 358
ILE A 203
ILE A 357
VAL A 214
ILE A 218
 None
 1.10A 3p4wB-3h1tA:
undetectable		 3p4wB-3h1tA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 3h1t TYPE I SITE-SPECIFIC
RESTRICTION-MODIFICA
TION SYSTEM, R
(RESTRICTION)
SUBUNIT
(Vibrio
vulnificus) 		5 / 10 TYR A 358
ILE A 203
ILE A 357
VAL A 214
ILE A 218
 None
 1.11A 3p4wD-3h1tA:
undetectable		 3p4wD-3h1tA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 3h1t TYPE I SITE-SPECIFIC
RESTRICTION-MODIFICA
TION SYSTEM, R
(RESTRICTION)
SUBUNIT
(Vibrio
vulnificus) 		5 / 10 TYR A 358
ILE A 203
ILE A 357
VAL A 214
ILE A 218
 None
 1.10A 3p4wE-3h1tA:
undetectable		 3p4wE-3h1tA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3O_A_DLUA399_1
(PFV INTEGRASE)		 3h1t TYPE I SITE-SPECIFIC
RESTRICTION-MODIFICA
TION SYSTEM, R
(RESTRICTION)
SUBUNIT
(Vibrio
vulnificus) 		4 / 7 ASP A 367
ASP A 368
GLN A  73
GLU A  72
 None
 1.12A 3s3oA-3h1tA:
undetectable		 3s3oA-3h1tA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3h1t TYPE I SITE-SPECIFIC
RESTRICTION-MODIFICA
TION SYSTEM, R
(RESTRICTION)
SUBUNIT
(Vibrio
vulnificus) 		3 / 3 PRO A 356
LEU A 202
HIS A 312
 None
 0.69A 4pevA-3h1tA:
undetectable		 4pevA-3h1tA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 3h1t TYPE I SITE-SPECIFIC
RESTRICTION-MODIFICA
TION SYSTEM, R
(RESTRICTION)
SUBUNIT
(Vibrio
vulnificus) 		4 / 4 ILE A 185
ASN A 188
ILE A 218
VAL A 214
 None
 1.05A 4uy87-3h1tA:
undetectable		 4uy87-3h1tA:
3.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 3h1t TYPE I SITE-SPECIFIC
RESTRICTION-MODIFICA
TION SYSTEM, R
(RESTRICTION)
SUBUNIT
(Vibrio
vulnificus) 		3 / 3 VAL A 526
THR A 558
ARG A 414
 None
 0.71A 5b2sB-3h1tA:
0.3		 5b2sB-3h1tA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 3h1t TYPE I SITE-SPECIFIC
RESTRICTION-MODIFICA
TION SYSTEM, R
(RESTRICTION)
SUBUNIT
(Vibrio
vulnificus) 		3 / 3 VAL A 526
THR A 558
ARG A 414
 None
 0.73A 5b2tB-3h1tA:
3.1		 5b2tB-3h1tA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 3h1t TYPE I SITE-SPECIFIC
RESTRICTION-MODIFICA
TION SYSTEM, R
(RESTRICTION)
SUBUNIT
(Vibrio
vulnificus) 		4 / 6 ASP A 367
TYR A 110
TYR A 181
LEU A 114
 None
 0.83A 5bmvB-3h1tA:
undetectable		 5bmvB-3h1tA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 3h1t TYPE I SITE-SPECIFIC
RESTRICTION-MODIFICA
TION SYSTEM, R
(RESTRICTION)
SUBUNIT
(Vibrio
vulnificus) 		4 / 4 TYR A 374
GLY A 365
SER A 361
LEU A 362
 None
 1.42A 5bphC-3h1tA:
2.3		 5bphC-3h1tA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 3h1t TYPE I SITE-SPECIFIC
RESTRICTION-MODIFICA
TION SYSTEM, R
(RESTRICTION)
SUBUNIT
(Vibrio
vulnificus) 		4 / 6 GLU A 112
PHE A 118
THR A 133
TYR A 132
 None
 1.39A 5lrbA-3h1tA:
undetectable		 5lrbA-3h1tA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZ0_A_ZLDA301_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ETHR)		 3h1t TYPE I SITE-SPECIFIC
RESTRICTION-MODIFICA
TION SYSTEM, R
(RESTRICTION)
SUBUNIT
(Vibrio
vulnificus) 		5 / 12 GLY A 336
ILE A 308
TYR A 350
THR A 349
TRP A 322
 None
 1.42A 5nz0A-3h1tA:
undetectable		 5nz0A-3h1tA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UL4_A_SAMA803_0
(OXSB PROTEIN)		 3h1t TYPE I SITE-SPECIFIC
RESTRICTION-MODIFICA
TION SYSTEM, R
(RESTRICTION)
SUBUNIT
(Vibrio
vulnificus) 		5 / 12 PHE A 552
ALA A 206
ARG A 542
GLY A 538
ILE A 554
 None
 1.17A 5ul4A-3h1tA:
undetectable		 5ul4A-3h1tA:
21.62