SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h20'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_0
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 3h20 REPLICATION PROTEIN
B
(Plasmid
RSF1010) 		5 / 12 PHE A  22
LEU A  45
ALA A  41
GLY A  11
LEU A  73
 None
 0.98A 1kglA-3h20A:
undetectable		 1kglA-3h20A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_1
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 3h20 REPLICATION PROTEIN
B
(Plasmid
RSF1010) 		4 / 5 PRO A 135
ALA A 136
ASP A  86
ASP A  78
 None
 1.18A 2nyuB-3h20A:
undetectable		 2nyuB-3h20A:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN3_A_ID8A1356_1
(THYROXINE-BINDING
GLOBULIN)		 3h20 REPLICATION PROTEIN
B
(Plasmid
RSF1010) 		4 / 8 LEU A  51
LYS A  52
ASN A  55
ARG A 145
 None
None
None
DPO  A 327 (-4.0A)
 0.75A 2xn3A-3h20A:
undetectable
2xn3B-3h20A:
undetectable		 2xn3A-3h20A:
20.22
2xn3B-3h20A:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_1
(MODIFICATION
METHYLASE HHAI)		 3h20 REPLICATION PROTEIN
B
(Plasmid
RSF1010) 		3 / 3 GLU A 223
SER A 252
VAL A 296
 None
 0.78A 3eeoA-3h20A:
undetectable		 3eeoA-3h20A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_1
(PROTEASE)		 3h20 REPLICATION PROTEIN
B
(Plasmid
RSF1010) 		5 / 12 LEU A 127
ALA A 133
ASP A  78
PRO A  94
VAL A  76
 None
 1.14A 3gguA-3h20A:
undetectable		 3gguA-3h20A:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_A_ACRA720_1
(ALPHA-AMYLASE, SUSG)		 3h20 REPLICATION PROTEIN
B
(Plasmid
RSF1010) 		4 / 7 GLU A  38
TRP A  39
LEU A  51
ASN A  47
 None
 1.42A 3k8mA-3h20A:
undetectable		 3k8mA-3h20A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_2
(HIV-1 PROTEASE)		 3h20 REPLICATION PROTEIN
B
(Plasmid
RSF1010) 		4 / 7 ARG A 145
GLY A  11
ILE A  10
VAL A  98
 DPO  A 327 (-4.0A)
None
None
None
 0.70A 3ufnB-3h20A:
undetectable		 3ufnB-3h20A:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3h20 REPLICATION PROTEIN
B
(Plasmid
RSF1010) 		5 / 12 GLY A  72
ILE A 123
LEU A 119
GLY A 179
GLY A 173
 None
 1.05A 5d4uB-3h20A:
undetectable		 5d4uB-3h20A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3h20 REPLICATION PROTEIN
B
(Plasmid
RSF1010) 		3 / 3 VAL A  97
TYR A 105
GLN A 106
 None
 0.60A 5qgkA-3h20A:
undetectable		 5qgkA-3h20A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3h20 REPLICATION PROTEIN
B
(Plasmid
RSF1010) 		3 / 3 VAL A  97
TYR A 105
GLN A 106
 None
 0.58A 5qgrA-3h20A:
undetectable		 5qgrA-3h20A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3h20 REPLICATION PROTEIN
B
(Plasmid
RSF1010) 		3 / 3 VAL A  97
TYR A 105
GLN A 106
 None
 0.63A 5qgtA-3h20A:
undetectable		 5qgtA-3h20A:
18.46