SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h2d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 3h2d CHEC-LIKE
SUPERFAMILY PROTEIN
(Shewanella
oneidensis) 		5 / 12 GLY A 123
GLY A 121
ILE A 126
LEU A  13
PRO A 138
 None
 1.10A 1p91B-3h2dA:
undetectable		 1p91B-3h2dA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_0
(HEMK PROTEIN)		 3h2d CHEC-LIKE
SUPERFAMILY PROTEIN
(Shewanella
oneidensis) 		5 / 12 ILE A  59
GLY A  44
ILE A  46
VAL A  42
SER A 120
 None
 0.96A 1sg9B-3h2dA:
undetectable		 1sg9B-3h2dA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)		 3h2d CHEC-LIKE
SUPERFAMILY PROTEIN
(Shewanella
oneidensis) 		4 / 7 PHE A   9
PHE A 111
GLY A  55
THR A  53
 None
 0.84A 4ejjA-3h2dA:
undetectable		 4ejjA-3h2dA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_B_NCTB501_1
(CYTOCHROME P450 2A6)		 3h2d CHEC-LIKE
SUPERFAMILY PROTEIN
(Shewanella
oneidensis) 		4 / 7 PHE A   9
PHE A 111
GLY A  55
THR A  53
 None
 0.82A 4ejjB-3h2dA:
undetectable		 4ejjB-3h2dA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 3h2d CHEC-LIKE
SUPERFAMILY PROTEIN
(Shewanella
oneidensis) 		4 / 5 PHE A   9
PHE A 111
GLY A  55
THR A  53
 None
 0.89A 4ejjC-3h2dA:
undetectable		 4ejjC-3h2dA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 3h2d CHEC-LIKE
SUPERFAMILY PROTEIN
(Shewanella
oneidensis) 		5 / 12 ILE A  17
ALA A 146
TYR A 143
SER A 141
LEU A  23
 None
 1.15A 4qztC-3h2dA:
undetectable		 4qztC-3h2dA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_A_TRPA403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 3h2d CHEC-LIKE
SUPERFAMILY PROTEIN
(Shewanella
oneidensis) 		4 / 8 GLU A  91
THR A  97
ILE A  46
PRO A 116
 None
 0.97A 6a4iA-3h2dA:
undetectable		 6a4iA-3h2dA:
17.60