SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h2i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_SAMA635_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		5 / 12 TYR A 125
GLY A 207
GLY A 179
LEU A 330
PRO A 204
 None
 1.22A 1qzzA-3h2iA:
2.1		 1qzzA-3h2iA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		4 / 8 PHE A 269
LEU A 275
GLY A 231
TYR A 138
 None
 0.90A 1rmtC-3h2iA:
undetectable		 1rmtC-3h2iA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B82_A_ADNA1001_1
(CLASS B ACID
PHOSPHATASE)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		5 / 10 PHE A 269
GLU A  89
LEU A 275
GLY A 231
TYR A 138
 None
 1.26A 2b82A-3h2iA:
undetectable		 2b82A-3h2iA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B82_B_ADNB1002_1
(CLASS B ACID
PHOSPHATASE)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		5 / 9 PHE A 269
GLU A  89
LEU A 275
GLY A 231
TYR A 138
 None
 1.24A 2b82B-3h2iA:
1.4		 2b82B-3h2iA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_A_SAMA1500_0
(ASPARTOKINASE)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		4 / 8 ILE A 149
SER A 146
LEU A 193
GLU A 196
 None
 0.78A 2cdqA-3h2iA:
undetectable		 2cdqA-3h2iA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		5 / 11 ILE A  54
HIS A 140
LEU A 126
GLY A  58
GLU A  57
 None
 1.41A 2fn1A-3h2iA:
undetectable		 2fn1A-3h2iA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_1
(PROTEASE)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		5 / 12 LEU A 128
ALA A 147
ASP A 150
GLY A  55
VAL A  56
 None
 1.16A 2o4lA-3h2iA:
undetectable		 2o4lA-3h2iA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UYQ_A_SAMA1311_0
(HYPOTHETICAL PROTEIN
ML2640)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		5 / 7 ALA A 203
VAL A 362
ASP A 390
LEU A 393
ARG A 389
 None
 1.34A 2uyqA-3h2iA:
undetectable		 2uyqA-3h2iA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		4 / 7 PHE A 310
PRO A 208
LEU A 139
ALA A 238
 None
 1.16A 2vcvA-3h2iA:
undetectable		 2vcvA-3h2iA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		4 / 7 PHE A 310
PRO A 208
LEU A 139
ALA A 238
 None
 1.09A 2vcvL-3h2iA:
undetectable		 2vcvL-3h2iA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		3 / 3 PRO A 165
GLY A  77
TYR A  79
 None
 0.73A 2vouA-3h2iA:
undetectable		 2vouA-3h2iA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		3 / 3 PHE A 302
ASN A 308
PHE A 298
 None
 1.06A 2zbuD-3h2iA:
undetectable		 2zbuD-3h2iA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DLC_A_SAMA220_0
(PUTATIVE
S-ADENOSYL-L-METHION
INE-DEPENDENT
METHYLTRANSFERASE)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		5 / 12 TYR A 299
GLY A 221
ASP A 336
VAL A 339
HIS A 377
 None
 1.37A 3dlcA-3h2iA:
undetectable		 3dlcA-3h2iA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA270_0
(PROTEIN SSM1)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		4 / 5 LEU A 139
SER A 141
LEU A 211
PRO A 208
 None
 1.03A 3onnA-3h2iA:
3.6		 3onnA-3h2iA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP7_B_SVRB499_1
(PYRUVATE KINASE)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		5 / 10 PRO A 340
ASN A 335
GLY A 332
GLY A 226
ALA A 337
 None
 1.49A 3pp7B-3h2iA:
4.6		 3pp7B-3h2iA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		4 / 8 GLY A 235
SER A 236
TYR A 293
THR A 229
 None
 0.76A 3pwwA-3h2iA:
undetectable		 3pwwA-3h2iA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_2
(NEURAMINIDASE)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		3 / 3 ARG A 187
ARG A 354
TRP A 322
 None
 1.38A 4b7nA-3h2iA:
undetectable		 4b7nA-3h2iA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		3 / 3 ARG A 187
ARG A 354
TRP A 322
 None
 1.42A 4cpzC-3h2iA:
undetectable		 4cpzC-3h2iA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		3 / 3 ARG A 187
ARG A 354
TRP A 322
 None
 1.43A 4cpzE-3h2iA:
undetectable		 4cpzE-3h2iA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		3 / 3 ARG A 187
ARG A 354
TRP A 322
 None
 1.33A 4cpzF-3h2iA:
undetectable		 4cpzF-3h2iA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		3 / 3 ARG A 187
ARG A 354
TRP A 322
 None
 1.32A 4cpzG-3h2iA:
undetectable		 4cpzG-3h2iA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		3 / 3 ARG A 187
ARG A 354
TRP A 322
 None
 1.37A 4cpzH-3h2iA:
undetectable		 4cpzH-3h2iA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA302_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		4 / 5 HIS A 377
TYR A 209
GLY A 207
SER A 176
 None
 1.27A 4fu8A-3h2iA:
undetectable		 4fu8A-3h2iA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_3
(HIV-1 PROTEASE)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		3 / 3 ASP A 390
LEU A 329
VAL A 200
 None
 0.58A 4jecB-3h2iA:
undetectable		 4jecB-3h2iA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		4 / 7 LEU A 233
PRO A  87
SER A 176
MET A 378
 None
 1.27A 4klrA-3h2iA:
2.6		 4klrA-3h2iA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QKN_A_JMSA602_1
(ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		4 / 8 THR A 164
LEU A  81
VAL A 158
SER A 157
 None
 0.96A 4qknA-3h2iA:
undetectable		 4qknA-3h2iA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		5 / 12 HIS A 140
ALA A 142
SER A 146
LEU A 126
PRO A 137
 None
 1.10A 4uilH-3h2iA:
undetectable
4uilL-3h2iA:
undetectable		 4uilH-3h2iA:
20.76
4uilL-3h2iA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		5 / 12 TYR A 175
LEU A 139
PHE A 310
PHE A 215
HIS A 377
 None
 1.28A 4ze1A-3h2iA:
undetectable		 4ze1A-3h2iA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		5 / 12 LEU A 211
HIS A 377
PRO A 204
ASP A 336
LEU A 361
 None
 1.39A 5dv4A-3h2iA:
undetectable		 5dv4A-3h2iA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		3 / 3 TRP A 261
ILE A 232
SER A 236
 None
 0.99A 5gqbA-3h2iA:
undetectable		 5gqbA-3h2iA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		5 / 12 ALA A 182
GLY A 178
SER A 206
GLY A  83
LEU A 392
 None
 1.12A 5gwxA-3h2iA:
2.0		 5gwxA-3h2iA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		5 / 12 THR A 181
GLY A  83
LEU A  67
ALA A 154
LEU A   7
 None
 1.43A 5jglB-3h2iA:
undetectable		 5jglB-3h2iA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_2
(WTFP-TAG,GP41)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		3 / 3 LEU A 211
LEU A 319
TRP A 322
 None
 0.93A 5nwuA-3h2iA:
undetectable		 5nwuA-3h2iA:
8.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		3 / 3 GLY A 127
LEU A 128
HIS A 136
 None
 0.49A 5u63A-3h2iA:
1.6		 5u63A-3h2iA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		3 / 3 GLY A 127
LEU A 128
HIS A 136
 None
 0.48A 5u63B-3h2iA:
1.7		 5u63B-3h2iA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3h2i ESTERASE
(Xanthomonas
oryzae) 		4 / 5 PRO A 296
GLY A 297
TYR A 299
VAL A 256
 None
 1.34A 5x80C-3h2iA:
undetectable
5x80D-3h2iA:
undetectable		 5x80C-3h2iA:
17.18
5x80D-3h2iA:
17.18