SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h2t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		4 / 7 PHE A 517
VAL A 538
ILE A 592
GLY A 556
 None
 0.86A 11gsA-3h2tA:
undetectable		 11gsA-3h2tA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		5 / 11 VAL A 541
ILE A 540
LEU A 611
ILE A 606
PHE A 515
 None
 1.00A 1yatA-3h2tA:
undetectable		 1yatA-3h2tA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		5 / 10 ALA A 559
ILE A 555
GLU A 565
ILE A 609
TYR A 590
 None
 1.20A 2dm6A-3h2tA:
undetectable
2dm6B-3h2tA:
undetectable		 2dm6A-3h2tA:
22.46
2dm6B-3h2tA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		4 / 8 PHE A 517
VAL A 538
ILE A 592
GLY A 556
 None
 0.85A 2gssA-3h2tA:
undetectable		 2gssA-3h2tA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		4 / 8 PHE A 517
VAL A 538
ILE A 592
GLY A 556
 None
 0.85A 2gssB-3h2tA:
undetectable		 2gssB-3h2tA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		4 / 6 LEU A 465
PHE A 459
ILE A 482
ALA A 480
 None
 1.08A 2j5mA-3h2tA:
undetectable		 2j5mA-3h2tA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		4 / 7 PHE A 517
VAL A 538
ILE A 592
GLY A 556
 None
 0.86A 3gssA-3h2tA:
undetectable		 3gssA-3h2tA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		4 / 7 PHE A 517
VAL A 538
ILE A 592
GLY A 556
 None
 0.86A 3gssB-3h2tA:
undetectable		 3gssB-3h2tA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		4 / 8 PHE A 517
VAL A 538
ILE A 592
GLY A 556
 None
 0.89A 3hjoA-3h2tA:
undetectable		 3hjoA-3h2tA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		4 / 8 PHE A 517
VAL A 538
ILE A 592
GLY A 556
 None
 0.88A 3hjoB-3h2tA:
undetectable		 3hjoB-3h2tA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		5 / 11 ILE A 621
ILE A 602
ILE A 592
VAL A 553
GLY A 593
 None
 0.80A 3kw4A-3h2tA:
undetectable		 3kw4A-3h2tA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		4 / 8 PHE A 517
VAL A 538
ILE A 592
GLY A 556
 None
 0.92A 3n9jA-3h2tA:
undetectable		 3n9jA-3h2tA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_2
(PROTEASE)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		5 / 9 ALA A 471
ASP A 470
GLY A 477
ILE A 476
ILE A 440
 None
 1.13A 3ndwB-3h2tA:
undetectable		 3ndwB-3h2tA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		5 / 11 ARG A 586
VAL A 541
ILE A 540
ILE A 606
PHE A 515
 None
 1.30A 3o5rA-3h2tA:
undetectable		 3o5rA-3h2tA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		4 / 7 VAL A 468
LEU A 651
ASN A 644
ILE A 653
 None
 0.96A 3rfmA-3h2tA:
undetectable		 3rfmA-3h2tA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		5 / 10 ARG A 586
VAL A 541
ILE A 540
ILE A 606
PHE A 515
 None
 1.33A 3uqaA-3h2tA:
undetectable		 3uqaA-3h2tA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		3 / 3 GLN A 361
THR A 634
ASN A 456
 None
 0.86A 3v4tE-3h2tA:
undetectable		 3v4tE-3h2tA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		5 / 11 ARG A 586
VAL A 541
ILE A 540
ILE A 606
PHE A 515
 None
 1.23A 4dz2A-3h2tA:
undetectable
4dz2B-3h2tA:
undetectable		 4dz2A-3h2tA:
18.46
4dz2B-3h2tA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		5 / 11 TYR A 536
ASP A 562
ARG A 521
TYR A 590
ILE A 609
 None
 1.19A 4dz2A-3h2tA:
undetectable
4dz2B-3h2tA:
undetectable		 4dz2A-3h2tA:
18.46
4dz2B-3h2tA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		5 / 11 ARG A 586
VAL A 541
ILE A 540
ILE A 606
PHE A 515
 None
 1.17A 4dz2A-3h2tA:
undetectable
4dz2B-3h2tA:
undetectable		 4dz2A-3h2tA:
18.46
4dz2B-3h2tA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		5 / 11 TYR A 536
ASP A 562
ARG A 521
TYR A 590
ILE A 609
 None
 1.14A 4dz2A-3h2tA:
undetectable
4dz2B-3h2tA:
undetectable		 4dz2A-3h2tA:
18.46
4dz2B-3h2tA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		5 / 10 ARG A 586
VAL A 541
ILE A 540
ILE A 606
PHE A 515
 None
 1.18A 4dz3A-3h2tA:
undetectable		 4dz3A-3h2tA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		5 / 10 TYR A 536
ASP A 562
ARG A 521
TYR A 590
ILE A 609
 None
 1.17A 4dz3A-3h2tA:
undetectable		 4dz3A-3h2tA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		5 / 12 VAL A 541
ILE A 540
LEU A 611
ILE A 606
PHE A 515
 None
 1.05A 5b8iC-3h2tA:
undetectable		 5b8iC-3h2tA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		5 / 11 VAL A 541
ILE A 540
ILE A 609
ILE A 606
PHE A 515
 None
 1.23A 5hw8D-3h2tA:
undetectable		 5hw8D-3h2tA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		5 / 11 VAL A 541
ILE A 540
ILE A 609
ILE A 606
PHE A 515
 None
 1.20A 5hw8G-3h2tA:
undetectable		 5hw8G-3h2tA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA607_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		4 / 4 GLY A 637
ARG A 486
ASN A 412
LEU A 639
 None
 1.16A 6b58A-3h2tA:
undetectable		 6b58A-3h2tA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J21_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		5 / 12 PRO A 378
ILE A 357
ILE A 392
VAL A 349
PHE A 455
 None
 1.46A 6j21A-3h2tA:
undetectable		 6j21A-3h2tA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		5 / 10 ARG A 586
VAL A 541
ILE A 540
ILE A 606
PHE A 515
 None
 1.34A 6mkeC-3h2tA:
undetectable		 6mkeC-3h2tA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 3h2t BASEPLATE STRUCTURAL
PROTEIN GP6
(Escherichia
virus
T4) 		5 / 10 ARG A 586
VAL A 541
ILE A 540
ILE A 606
PHE A 515
 None
 1.35A 6mkeD-3h2tA:
undetectable		 6mkeD-3h2tA:
13.13