SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h2y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 3h2y GTPASE FAMILY
PROTEIN
(Bacillus
anthracis) 		4 / 8 THR A 218
PRO A 219
GLY A 220
LEU A  63
 None
 0.82A 1h4oG-3h2yA:
undetectable		 1h4oG-3h2yA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3h2y GTPASE FAMILY
PROTEIN
(Bacillus
anthracis) 		4 / 5 PHE A 336
PHE A 280
HIS A 279
VAL A 334
 None
 1.24A 2lh6A-3h2yA:
undetectable		 2lh6A-3h2yA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_1
(PROTEASE)		 3h2y GTPASE FAMILY
PROTEIN
(Bacillus
anthracis) 		5 / 12 ARG A 288
LEU A 258
ASP A 333
ILE A 351
ILE A 327
 None
 1.01A 2o4nA-3h2yA:
undetectable		 2o4nA-3h2yA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 3h2y GTPASE FAMILY
PROTEIN
(Bacillus
anthracis) 		4 / 7 LEU A 150
PHE A 176
ILE A 154
PHE A 184
 None
 0.87A 2opxA-3h2yA:
2.1		 2opxA-3h2yA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3h2y GTPASE FAMILY
PROTEIN
(Bacillus
anthracis) 		5 / 12 SER A 362
VAL A 334
THR A 257
ILE A 351
PHE A 266
 None
 1.26A 2vdyA-3h2yA:
undetectable		 2vdyA-3h2yA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 3h2y GTPASE FAMILY
PROTEIN
(Bacillus
anthracis) 		4 / 7 THR A 218
PRO A 219
GLY A 220
LEU A  63
 None
 0.80A 2vl2B-3h2yA:
undetectable		 2vl2B-3h2yA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3h2y GTPASE FAMILY
PROTEIN
(Bacillus
anthracis) 		5 / 12 HIS A 354
ASP A 267
THR A 257
LEU A 320
PHE A 336
 None
 1.20A 3g1uB-3h2yA:
3.0		 3g1uB-3h2yA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3h2y GTPASE FAMILY
PROTEIN
(Bacillus
anthracis) 		5 / 12 HIS A 354
ASP A 267
THR A 257
LEU A 320
PHE A 336
 None
 1.17A 3g1uD-3h2yA:
3.0		 3g1uD-3h2yA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)		 3h2y GTPASE FAMILY
PROTEIN
(Bacillus
anthracis) 		4 / 7 PHE A 259
GLY A 262
PHE A 266
PHE A 336
 None
 0.99A 3ko0D-3h2yA:
undetectable
3ko0E-3h2yA:
undetectable		 3ko0D-3h2yA:
13.39
3ko0E-3h2yA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 3h2y GTPASE FAMILY
PROTEIN
(Bacillus
anthracis) 		4 / 8 PHE A 259
GLY A 262
PHE A 266
PHE A 336
 None
 0.95A 3ko0O-3h2yA:
undetectable
3ko0Q-3h2yA:
undetectable		 3ko0O-3h2yA:
13.39
3ko0Q-3h2yA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3h2y GTPASE FAMILY
PROTEIN
(Bacillus
anthracis) 		5 / 12 HIS A 354
ASP A 267
THR A 257
LEU A 320
PHE A 336
 None
 1.21A 3n58C-3h2yA:
undetectable		 3n58C-3h2yA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 3h2y GTPASE FAMILY
PROTEIN
(Bacillus
anthracis) 		4 / 5 ASP A  81
SER A 337
SER A 362
GLY A  84
 None
 1.03A 3rxhA-3h2yA:
undetectable		 3rxhA-3h2yA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_0
(METHYLTRANSFERASE
NSUN4)		 3h2y GTPASE FAMILY
PROTEIN
(Bacillus
anthracis) 		5 / 12 GLY A 159
GLY A 160
LYS A 161
GLY A  95
ASP A  70
 None
 1.04A 4fp9A-3h2yA:
undetectable		 4fp9A-3h2yA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_0
(METHYLTRANSFERASE
NSUN4)		 3h2y GTPASE FAMILY
PROTEIN
(Bacillus
anthracis) 		5 / 12 GLY A 159
GLY A 160
LYS A 161
GLY A  95
ASP A  70
 None
 1.04A 4fp9C-3h2yA:
undetectable		 4fp9C-3h2yA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_0
(METHYLTRANSFERASE
NSUN4)		 3h2y GTPASE FAMILY
PROTEIN
(Bacillus
anthracis) 		5 / 12 GLY A 159
GLY A 160
LYS A 161
GLY A  95
ASP A  70
 None
 1.04A 4fp9F-3h2yA:
undetectable		 4fp9F-3h2yA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RUJ_A_VDXA501_1
(VITAMIN D3 RECEPTOR
A)		 3h2y GTPASE FAMILY
PROTEIN
(Bacillus
anthracis) 		5 / 12 VAL A 231
SER A 235
ILE A 239
SER A 261
VAL A 359
 None
 1.42A 4rujA-3h2yA:
undetectable		 4rujA-3h2yA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE0_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3h2y GTPASE FAMILY
PROTEIN
(Bacillus
anthracis) 		5 / 9 PHE A  59
ILE A 221
GLY A  89
LEU A 131
LEU A 101
 None
 1.31A 4ze0A-3h2yA:
undetectable		 4ze0A-3h2yA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZGF_A_BEZA210_0
(UNCHARACTERIZED
PROTEIN)		 3h2y GTPASE FAMILY
PROTEIN
(Bacillus
anthracis) 		4 / 4 VAL A 231
ALA A 228
ASN A 170
GLN A 226
 None
None
DGI  A 369 (-3.9A)
None
 1.34A 4zgfA-3h2yA:
undetectable		 4zgfA-3h2yA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3h2y GTPASE FAMILY
PROTEIN
(Bacillus
anthracis) 		5 / 12 HIS A 354
ASP A 267
THR A 257
LEU A 320
PHE A 336
 None
 1.19A 5m66A-3h2yA:
2.5		 5m66A-3h2yA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_F_ADNF503_1
(ADENOSYLHOMOCYSTEINA
SE)		 3h2y GTPASE FAMILY
PROTEIN
(Bacillus
anthracis) 		5 / 12 HIS A 354
ASP A 267
THR A 257
LEU A 320
PHE A 336
 None
 1.34A 5utuF-3h2yA:
2.8		 5utuF-3h2yA:
23.03