SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h32'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3h32 FIBRINOGEN ALPHA
CHAIN
FIBRINOGEN BETA
CHAIN
(Homo
sapiens) 		4 / 6 ILE A 156
TRP B 317
GLY B 434
GLY B 414
 None
 0.77A 2qx6A-3h32A:
undetectable
2qx6B-3h32A:
undetectable		 2qx6A-3h32A:
19.69
2qx6B-3h32A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_A_T44A128_1
(TRANSTHYRETIN)		 3h32 FIBRINOGEN BETA
CHAIN
(Homo
sapiens) 		4 / 4 LYS B 323
LEU B 311
ALA B 324
LEU B 310
 None
 1.49A 2roxA-3h32B:
undetectable		 2roxA-3h32B:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3h32 FIBRINOGEN ALPHA
CHAIN
FIBRINOGEN BETA
CHAIN
(Homo
sapiens;
Homo
sapiens) 		5 / 12 ASN B 160
THR B 163
VAL A 130
ILE A 133
GLN A 137
 None
 1.49A 3em0A-3h32B:
undetectable		 3em0A-3h32B:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 3h32 FIBRINOGEN ALPHA
CHAIN
FIBRINOGEN BETA
CHAIN
(Homo
sapiens;
Homo
sapiens) 		3 / 3 LYS A 157
ARG B 415
ASP A 146
 None
 1.45A 3o7wA-3h32A:
undetectable		 3o7wA-3h32A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 3h32 FIBRINOGEN BETA
CHAIN
(Homo
sapiens) 		5 / 12 TYR B 269
GLY B 400
TYR B 378
ALA B 410
PHE B 375
 None
 1.19A 3vywA-3h32B:
undetectable		 3vywA-3h32B:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 3h32 FIBRINOGEN BETA
CHAIN
(Homo
sapiens) 		5 / 12 TYR B 269
GLY B 400
TYR B 378
ALA B 410
PHE B 375
 None
 1.20A 3vywB-3h32B:
undetectable		 3vywB-3h32B:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 3h32 FIBRINOGEN BETA
CHAIN
(Homo
sapiens) 		5 / 12 TYR B 269
GLY B 400
TYR B 378
ALA B 410
PHE B 375
 None
 1.20A 3vywD-3h32B:
undetectable		 3vywD-3h32B:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_1
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 3h32 FIBRINOGEN BETA
CHAIN
(Homo
sapiens) 		5 / 12 ALA B 410
VAL B 436
GLU B 291
PHE B 273
TYR B 404
 None
 1.47A 4zj8A-3h32B:
undetectable		 4zj8A-3h32B:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3h32 FIBRINOGEN BETA
CHAIN
(Homo
sapiens) 		4 / 7 ILE B 299
LEU B 294
GLY B 272
GLY B 295
 None
 0.84A 5a06A-3h32B:
undetectable		 5a06A-3h32B:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3h32 FIBRINOGEN BETA
CHAIN
(Homo
sapiens) 		4 / 7 ILE B 299
LEU B 294
GLY B 272
GLY B 295
 None
 0.83A 5a06C-3h32B:
undetectable		 5a06C-3h32B:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3h32 FIBRINOGEN BETA
CHAIN
(Homo
sapiens) 		4 / 7 ILE B 299
LEU B 294
GLY B 272
GLY B 295
 None
 0.82A 5a06E-3h32B:
undetectable		 5a06E-3h32B:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3h32 FIBRINOGEN BETA
CHAIN
(Homo
sapiens) 		4 / 7 ILE B 299
LEU B 294
GLY B 272
GLY B 295
 None
 0.84A 5a06F-3h32B:
undetectable		 5a06F-3h32B:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3h32 FIBRINOGEN BETA
CHAIN
(Homo
sapiens) 		4 / 6 SER B 451
GLU B 313
GLY B 272
GLY B 274
 None
 0.95A 5cdnT-3h32B:
undetectable
5cdnU-3h32B:
undetectable		 5cdnT-3h32B:
21.07
5cdnU-3h32B:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3h32 FIBRINOGEN BETA
CHAIN
(Homo
sapiens) 		4 / 5 ALA B 357
PRO B 412
GLY B 295
LEU B 310
 None
 0.97A 5eslA-3h32B:
undetectable		 5eslA-3h32B:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I75_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3h32 FIBRINOGEN ALPHA
CHAIN
FIBRINOGEN BETA
CHAIN
(Homo
sapiens) 		5 / 12 GLY B 263
PHE B 262
SER A 160
GLY B 258
GLY B 272
 None
 1.05A 5i75A-3h32B:
undetectable		 5i75A-3h32B:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_1
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 3h32 FIBRINOGEN BETA
CHAIN
(Homo
sapiens) 		4 / 4 SER B 376
ASP B 398
HIS B 408
ASP B 383
 None
None
None
CA  B 502 (-2.6A)
 1.50A 5x7fA-3h32B:
0.0		 5x7fA-3h32B:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3h32 FIBRINOGEN BETA
CHAIN
(Homo
sapiens) 		5 / 9 GLY B 414
TYR B 404
ASP B 433
GLY B 434
PRO B 412
 None
 1.32A 5zniA-3h32B:
undetectable		 5zniA-3h32B:
11.16