SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h3d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 3h3d MATERNAL PROTEIN
PUMILIO
(Drosophila
melanogaster) 		5 / 10 LEU X 208
LEU X 201
ILE X 218
GLU X 151
LEU X 186
 None
 1.05A 1wopA-3h3dX:
undetectable		 1wopA-3h3dX:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3h3d MATERNAL PROTEIN
PUMILIO
(Drosophila
melanogaster) 		5 / 12 GLN X 103
VAL X 109
GLY X 106
ALA X  61
ALA X  60
 None
 0.93A 3sufB-3h3dX:
undetectable		 3sufB-3h3dX:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3h3d MATERNAL PROTEIN
PUMILIO
(Drosophila
melanogaster) 		4 / 6 LEU X 222
GLN X 183
LEU X 186
GLU X 187
 None
 1.05A 4nc3A-3h3dX:
undetectable		 4nc3A-3h3dX:
19.63