SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h3l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 3h3l PUTATIVE SUGAR
HYDROLASE
(Parabacteroides
distasonis) 		3 / 3 GLU A 111
TRP A  52
LYS A  86
 None
 1.40A 1qu2A-3h3lA:
undetectable		 1qu2A-3h3lA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3h3l PUTATIVE SUGAR
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 GLN A 144
ASN A 161
GLY A 160
ASP A 159
MET A 200
 None
 1.19A 2zw9A-3h3lA:
undetectable		 2zw9A-3h3lA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 3h3l PUTATIVE SUGAR
HYDROLASE
(Parabacteroides
distasonis) 		3 / 3 TYR A 138
TYR A  67
ILE A 136
 None
 0.84A 3eteA-3h3lA:
undetectable
3eteB-3h3lA:
undetectable		 3eteA-3h3lA:
20.09
3eteB-3h3lA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3h3l PUTATIVE SUGAR
HYDROLASE
(Parabacteroides
distasonis) 		3 / 3 CYH A 234
PRO A 231
ASP A 169
 None
 0.93A 3hlwB-3h3lA:
undetectable		 3hlwB-3h3lA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 3h3l PUTATIVE SUGAR
HYDROLASE
(Parabacteroides
distasonis) 		3 / 3 PRO A 135
THR A 134
LEU A 240
 None
 0.73A 3ttrA-3h3lA:
undetectable		 3ttrA-3h3lA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 3h3l PUTATIVE SUGAR
HYDROLASE
(Parabacteroides
distasonis) 		4 / 6 THR A  60
ASN A  62
GLY A  63
ILE A 265
 None
 1.03A 3w9tF-3h3lA:
undetectable		 3w9tF-3h3lA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_C_MIYC392_1
(TETX2 PROTEIN)		 3h3l PUTATIVE SUGAR
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 GLU A 207
PHE A 210
VAL A 167
ILE A 171
ILE A 197
 None
 1.22A 4a99A-3h3lA:
undetectable
4a99C-3h3lA:
undetectable		 4a99A-3h3lA:
21.70
4a99C-3h3lA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)		 3h3l PUTATIVE SUGAR
HYDROLASE
(Parabacteroides
distasonis) 		3 / 3 CYH A 234
PRO A 231
ASP A 169
 None
 0.88A 4pm5A-3h3lA:
undetectable		 4pm5A-3h3lA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)		 3h3l PUTATIVE SUGAR
HYDROLASE
(Parabacteroides
distasonis) 		4 / 7 PHE A  56
ASP A  57
GLY A  81
THR A  60
 None
 1.13A 4zxiA-3h3lA:
undetectable		 4zxiA-3h3lA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 3h3l PUTATIVE SUGAR
HYDROLASE
(Parabacteroides
distasonis) 		3 / 3 ASP A  71
ASP A  98
ASN A 121
 None
 0.85A 6gngB-3h3lA:
undetectable		 6gngB-3h3lA:
18.77