SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h41'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_A_T3A1_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 ILE A 215
ILE A 302
LEU A 214
LEU A 277
ILE A 253
 PG4  A   2 (-3.7A)
None
None
None
None
 1.15A 1bsxA-3h41A:
undetectable		 1bsxA-3h41A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_B_T3B2_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 ILE A 215
ILE A 302
LEU A 214
LEU A 277
ILE A 253
 PG4  A   2 (-3.7A)
None
None
None
None
 1.15A 1bsxB-3h41A:
undetectable		 1bsxB-3h41A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		3 / 3 GLN A 109
HIS A 243
PRO A 254
 None
 0.65A 1d8cA-3h41A:
undetectable		 1d8cA-3h41A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GXS_A_BEZA601_0
(P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
A
P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
B)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		4 / 7 ASP A 237
SER A 257
TRP A 228
ALA A 229
 DGL  A 502 ( 3.7A)
DGL  A 502 (-2.8A)
ALA  A 501 ( 3.7A)
ALA  A 501 ( 3.8A)
 1.00A 1gxsA-3h41A:
undetectable
1gxsB-3h41A:
undetectable		 1gxsA-3h41A:
20.00
1gxsB-3h41A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA733_1
(ALPHA AMYLASE)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		4 / 6 SER A 165
THR A 148
LEU A 192
ASP A 196
 None
 1.33A 1mxdA-3h41A:
undetectable		 1mxdA-3h41A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 ILE A 215
ILE A 302
LEU A 214
LEU A 277
ILE A 253
 PG4  A   2 (-3.7A)
None
None
None
None
 1.23A 1xzxX-3h41A:
undetectable		 1xzxX-3h41A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		4 / 6 THR A  84
ALA A 229
ARG A 255
PRO A 119
 None
ALA  A 501 ( 3.8A)
ALA  A 501 ( 4.1A)
None
 1.02A 2ql8A-3h41A:
undetectable
2ql8B-3h41A:
undetectable		 2ql8A-3h41A:
18.51
2ql8B-3h41A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 ILE A 227
GLY A 230
GLN A  85
LEU A  74
THR A  39
 None
 0.64A 3eeyC-3h41A:
undetectable		 3eeyC-3h41A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 ILE A 227
GLY A 230
GLN A  85
LEU A  74
THR A  39
 None
 0.67A 3eeyE-3h41A:
undetectable		 3eeyE-3h41A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 ILE A 227
GLY A 230
GLN A  85
LEU A  74
THR A  39
 None
 0.75A 3eeyF-3h41A:
undetectable		 3eeyF-3h41A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		4 / 7 GLY A 285
GLY A 287
GLU A 323
ALA A 326
 None
PG4  A   5 ( 4.4A)
None
None
 0.82A 3fpjB-3h41A:
undetectable		 3fpjB-3h41A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 235
GLY A 218
GLY A 233
THR A 217
ILE A 302
 None
 0.90A 3p97C-3h41A:
undetectable		 3p97C-3h41A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 235
GLY A 218
GLY A 233
THR A 217
ILE A 302
 None
 0.90A 4ctjC-3h41A:
undetectable		 4ctjC-3h41A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		4 / 8 GLN A 109
GLN A  90
ASN A 167
THR A 168
 None
 1.19A 4d1yA-3h41A:
undetectable
4d1yB-3h41A:
undetectable		 4d1yA-3h41A:
21.66
4d1yB-3h41A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		4 / 8 PRO A 209
GLN A 203
ILE A 253
MET A 294
 None
 1.07A 4iilA-3h41A:
undetectable		 4iilA-3h41A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 235
GLY A 218
GLY A 233
THR A 217
ILE A 302
 None
 0.89A 5e9qC-3h41A:
undetectable		 5e9qC-3h41A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 235
GLY A 218
GLY A 233
THR A 217
ILE A 302
 None
 0.90A 5ec8C-3h41A:
undetectable		 5ec8C-3h41A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 235
GLY A 218
GLY A 233
THR A 217
ILE A 302
 None
 0.90A 5ehgA-3h41A:
undetectable		 5ehgA-3h41A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 235
GLY A 218
GLY A 233
THR A 217
ILE A 302
 None
 0.87A 5ehgC-3h41A:
undetectable		 5ehgC-3h41A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 235
GLY A 218
GLY A 233
THR A 217
ILE A 302
 None
 0.89A 5eifC-3h41A:
undetectable		 5eifC-3h41A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		4 / 5 TRP A  41
LEU A 127
PRO A 123
LEU A  88
 None
None
PG4  A   3 ( 4.5A)
None
 1.10A 5eshA-3h41A:
undetectable		 5eshA-3h41A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 235
GLY A 218
GLY A 233
THR A 217
ILE A 302
 None
 0.92A 5ikmA-3h41A:
undetectable		 5ikmA-3h41A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 235
GLY A 218
GLY A 233
THR A 217
ILE A 302
 None
 0.91A 5kqrA-3h41A:
undetectable		 5kqrA-3h41A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 235
GLY A 218
GLY A 233
THR A 217
ILE A 302
 None
 0.90A 5kqsA-3h41A:
undetectable		 5kqsA-3h41A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 235
GLY A 218
GLY A 233
THR A 217
ILE A 302
 None
 0.89A 5m5bA-3h41A:
undetectable		 5m5bA-3h41A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_A_SAMA301_0
(NS5)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 235
GLY A 218
GLY A 233
THR A 217
ILE A 302
 None
 0.89A 5njvA-3h41A:
undetectable		 5njvA-3h41A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 235
GLY A 218
GLY A 233
THR A 217
ILE A 302
 None
 0.86A 5wz1A-3h41A:
undetectable		 5wz1A-3h41A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 235
GLY A 218
GLY A 233
THR A 217
ILE A 302
 None
 0.85A 5wz1B-3h41A:
undetectable		 5wz1B-3h41A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 235
GLY A 218
GLY A 233
THR A 217
ILE A 302
 None
 0.87A 5wz1C-3h41A:
undetectable		 5wz1C-3h41A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 235
GLY A 218
GLY A 233
THR A 217
ILE A 302
 None
 0.85A 5wz1D-3h41A:
undetectable		 5wz1D-3h41A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 235
GLY A 218
GLY A 233
THR A 217
ILE A 302
 None
 0.89A 5wz1E-3h41A:
undetectable		 5wz1E-3h41A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 235
GLY A 218
GLY A 233
THR A 217
ILE A 302
 None
 0.85A 5wz1F-3h41A:
undetectable		 5wz1F-3h41A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 235
GLY A 218
GLY A 233
THR A 217
ILE A 302
 None
 0.87A 5wz1G-3h41A:
undetectable		 5wz1G-3h41A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 235
GLY A 218
GLY A 233
THR A 217
ILE A 302
 None
 0.89A 5wz1H-3h41A:
undetectable		 5wz1H-3h41A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 235
GLY A 218
GLY A 233
THR A 217
ILE A 302
 None
 0.88A 5wz2A-3h41A:
undetectable		 5wz2A-3h41A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 3h41 NLP/P60 FAMILY
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 235
GLY A 218
GLY A 233
THR A 217
ILE A 302
 None
 0.89A 5wz2C-3h41A:
undetectable		 5wz2C-3h41A:
21.28