SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h4q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 3h4q PUTATIVE
ACETYLTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 ALA A  20
GLU A  19
LEU A  23
ILE A  64
PRO A 131
 None
 1.13A 2qxsA-3h4qA:
undetectable		 2qxsA-3h4qA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 3h4q PUTATIVE
ACETYLTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 ALA A  20
GLU A  19
LEU A  23
ILE A  64
PRO A 131
 None
 1.13A 2qxsB-3h4qA:
undetectable		 2qxsB-3h4qA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA201_1
(PROTEIN S100-A4)		 3h4q PUTATIVE
ACETYLTRANSFERASE
(Staphylococcus
aureus) 		5 / 9 GLY A 140
ILE A  89
PHE A 126
PHE A 136
GLY A 134
 None
 1.35A 3ko0A-3h4qA:
undetectable
3ko0C-3h4qA:
undetectable		 3ko0A-3h4qA:
16.40
3ko0C-3h4qA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 3h4q PUTATIVE
ACETYLTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 GLY A  62
PHE A  63
ILE A  89
PHE A  42
 None
 0.85A 3ko0O-3h4qA:
undetectable
3ko0Q-3h4qA:
undetectable		 3ko0O-3h4qA:
16.40
3ko0Q-3h4qA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 3h4q PUTATIVE
ACETYLTRANSFERASE
(Staphylococcus
aureus) 		5 / 10 GLY A 140
ILE A  89
PHE A 126
PHE A 136
GLY A 134
 None
 1.33A 3ko0R-3h4qA:
undetectable
3ko0T-3h4qA:
undetectable		 3ko0R-3h4qA:
16.40
3ko0T-3h4qA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 3h4q PUTATIVE
ACETYLTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 ILE A  60
VAL A  53
ARG A   3
 None
 0.61A 3p73A-3h4qA:
undetectable		 3p73A-3h4qA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TF1_A_ACTA191_0
(METHYL-ACCEPTING
CHEMOTAXIS PROTEIN)		 3h4q PUTATIVE
ACETYLTRANSFERASE
(Staphylococcus
aureus) 		4 / 5 THR A 123
ILE A  89
PHE A 141
LEU A 128
 None
None
None
UNL  A 170 ( 4.1A)
 1.21A 3tf1A-3h4qA:
undetectable		 3tf1A-3h4qA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_A_1N1A601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3h4q PUTATIVE
ACETYLTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 MET A   1
ASP A   9
PHE A  63
 None
 0.90A 4xeyA-3h4qA:
undetectable		 4xeyA-3h4qA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3h4q PUTATIVE
ACETYLTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 MET A   1
ASP A   9
PHE A  63
 None
 0.86A 4xeyB-3h4qA:
undetectable		 4xeyB-3h4qA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 3h4q PUTATIVE
ACETYLTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 LEU A  51
VAL A  53
ILE A  60
LEU A  39
LEU A  14
 None
 1.06A 4yvpB-3h4qA:
undetectable		 4yvpB-3h4qA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3h4q PUTATIVE
ACETYLTRANSFERASE
(Staphylococcus
aureus) 		4 / 7 ILE A  60
GLU A  19
GLY A  94
GLY A  62
 None
None
UNL  A 170 (-4.1A)
None
 0.78A 5a06A-3h4qA:
undetectable		 5a06A-3h4qA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3h4q PUTATIVE
ACETYLTRANSFERASE
(Staphylococcus
aureus) 		4 / 7 ILE A  60
GLU A  19
GLY A  94
GLY A  62
 None
None
UNL  A 170 (-4.1A)
None
 0.80A 5a06C-3h4qA:
undetectable		 5a06C-3h4qA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3h4q PUTATIVE
ACETYLTRANSFERASE
(Staphylococcus
aureus) 		4 / 7 ILE A  60
GLU A  19
GLY A  94
GLY A  62
 None
None
UNL  A 170 (-4.1A)
None
 0.79A 5a06E-3h4qA:
undetectable		 5a06E-3h4qA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3h4q PUTATIVE
ACETYLTRANSFERASE
(Staphylococcus
aureus) 		4 / 7 ILE A  60
GLU A  19
GLY A  94
GLY A  62
 None
None
UNL  A 170 (-4.1A)
None
 0.78A 5a06F-3h4qA:
undetectable		 5a06F-3h4qA:
19.29