SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h4x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FM6_A_9CRA501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 12	ALA A 263 ALA A 288 TRP A 324 LEU A 267 ALA A 264	None None None None EOH A 348 ( 3.9A)	1.00A	1fm6A-3h4xA: undetectable	1fm6A-3h4xA: 22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MIC_A_DVAA6_0 (GRAMICIDIN A)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	3 / 3	ALA A 234 VAL A 257 TRP A 179	None	0.91A	1micA-3h4xA: undetectable 1micB-3h4xA: undetectable	1micA-3h4xA: 5.68 1micB-3h4xA: 5.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXE_A_1FLA2002_1 (SERUM ALBUMIN)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 10	ALA A 315 LEU A 312 LEU A 267 ALA A 263 SER A 270	None	1.04A	2bxeA-3h4xA: undetectable	2bxeA-3h4xA: 20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PLW_A_SAMA203_1 (RIBOSOMAL RNA METHYLTRANSFERASE, PUTATIVE)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	3 / 3	SER A 84 ASP A 50 ASP A 110	None	0.78A	2plwA-3h4xA: undetectable	2plwA-3h4xA: 17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YVL_C_SAMC604_1 (HYPOTHETICAL PROTEIN)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 4	GLY A 141 GLU A 144 ASP A 146 TYR A 213	ACE A 368 (-3.3A) ACE A 368 (-3.1A) None None	1.03A	2yvlC-3h4xA: undetectable	2yvlC-3h4xA: 20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B6H_B_MXDB551_1 (PROSTACYCLIN SYNTHASE)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 6	TYR A 213 ALA A 214 LEU A 217 ALA A 170	None	0.93A	3b6hB-3h4xA: undetectable	3b6hB-3h4xA: 21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3J6P_B_TA1B502_1 (TUBULIN BETA CHAIN)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 12	VAL A 74 ASP A 62 LEU A 153 SER A 84 LEU A 59	None	1.15A	3j6pB-3h4xA: undetectable	3j6pB-3h4xA: 21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JUS_A_ECLA600_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 8	LEU A 125 GLY A 187 ALA A 156 ILE A 149	None None ACT A 361 ( 4.0A) None	0.80A	3jusA-3h4xA: undetectable	3jusA-3h4xA: 23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JUS_A_ECNA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 8	LEU A 125 GLY A 187 ALA A 156 ILE A 149	None None ACT A 361 ( 4.0A) None	0.80A	3jusA-3h4xA: undetectable	3jusA-3h4xA: 23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T3Z_A_9PLA501_1 (CYTOCHROME P450 2E1)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 6	PHE A 145 LEU A 108 PHE A 191 LEU A 63	None	0.99A	3t3zA-3h4xA: undetectable	3t3zA-3h4xA: 20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WSJ_A_MK1A201_1 (PROTEASE)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 9	LEU A 312 ALA A 322 ASP A 323 VAL A 34 LEU A 331	None	1.16A	3wsjA-3h4xA: undetectable	3wsjA-3h4xA: 14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AT0_A_ACTA1490_0 (3-KETOSTEROID-DELTA4 -5ALPHA-DEHYDROGENAS E)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	3 / 3	GLU A 41 TYR A 40 SER A 75	None	0.56A	4at0A-3h4xA: undetectable	4at0A-3h4xA: 25.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CP3_B_RBTB1129_1 (B-CELL LYMPHOMA 6 PROTEIN)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 7	ARG A 73 LEU A 63 ARG A 140 GLY A 106	None None GOL A 366 ( 3.6A) EOH A 349 (-3.7A)	0.88A	4cp3A-3h4xA: undetectable 4cp3B-3h4xA: undetectable	4cp3A-3h4xA: 15.29 4cp3B-3h4xA: 15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EJW_A_SRYA2001_1 (TRANSCRIPTIONAL REGULATOR TCAR)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 12	ALA A 234 GLU A 192 HIS A 236 TYR A 247 ARG A 246	None None EOH A 358 (-4.0A) None None	1.37A	4ejwA-3h4xA: undetectable	4ejwA-3h4xA: 18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEU_B_KANB301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 7	ASP A 62 ASP A 287 ASN A 38 GLU A 129	None EOH A 348 ( 4.5A) None None	0.82A	4feuB-3h4xA: undetectable	4feuB-3h4xA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEU_D_KAND301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 8	ASP A 62 ASP A 287 ASN A 38 GLU A 129	None EOH A 348 ( 4.5A) None None	0.90A	4feuD-3h4xA: undetectable	4feuD-3h4xA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEU_F_KANF301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 8	ASP A 62 ASP A 287 ASN A 38 GLU A 129	None EOH A 348 ( 4.5A) None None	0.85A	4feuF-3h4xA: undetectable	4feuF-3h4xA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEV_B_KANB301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 7	ASP A 62 ASP A 287 ASN A 38 GLU A 129	None EOH A 348 ( 4.5A) None None	0.89A	4fevB-3h4xA: undetectable	4fevB-3h4xA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEV_B_KANB301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 7	ASP A 62 ASP A 287 GLU A 41 GLU A 129	None EOH A 348 ( 4.5A) None None	1.04A	4fevB-3h4xA: undetectable	4fevB-3h4xA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEV_D_KAND301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 7	ASP A 62 ASP A 287 ASN A 38 GLU A 129	None EOH A 348 ( 4.5A) None None	0.87A	4fevD-3h4xA: undetectable	4fevD-3h4xA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEV_F_KANF301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 7	ASP A 62 ASP A 287 ASN A 38 GLU A 129	None EOH A 348 ( 4.5A) None None	0.87A	4fevF-3h4xA: undetectable	4fevF-3h4xA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEW_B_KANB301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 7	ASP A 62 ASP A 287 ASN A 38 GLU A 129	None EOH A 348 ( 4.5A) None None	0.90A	4fewB-3h4xA: undetectable	4fewB-3h4xA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEW_B_KANB301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 7	ASP A 62 ASP A 287 GLU A 41 GLU A 129	None EOH A 348 ( 4.5A) None None	0.96A	4fewB-3h4xA: undetectable	4fewB-3h4xA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEW_D_KAND301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 8	ASP A 62 ASP A 287 ASN A 38 GLU A 129	None EOH A 348 ( 4.5A) None None	0.87A	4fewD-3h4xA: undetectable	4fewD-3h4xA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEW_F_KANF301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 8	ASP A 62 ASP A 287 ASN A 38 GLU A 129	None EOH A 348 ( 4.5A) None None	0.87A	4fewF-3h4xA: undetectable	4fewF-3h4xA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEX_B_KANB301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 7	ASP A 62 ASP A 287 ASN A 38 GLU A 129	None EOH A 348 ( 4.5A) None None	0.91A	4fexB-3h4xA: undetectable	4fexB-3h4xA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GKH_B_KANB301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 8	ASP A 62 ASP A 287 ASN A 38 GLU A 129	None EOH A 348 ( 4.5A) None None	0.89A	4gkhB-3h4xA: undetectable	4gkhB-3h4xA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GKH_D_KAND301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 8	ASP A 62 ASP A 287 ASN A 38 GLU A 129	None EOH A 348 ( 4.5A) None None	0.89A	4gkhD-3h4xA: undetectable	4gkhD-3h4xA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GKH_D_KAND301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 8	ASP A 62 ASP A 287 GLU A 41 GLU A 129	None EOH A 348 ( 4.5A) None None	0.97A	4gkhD-3h4xA: undetectable	4gkhD-3h4xA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GKH_F_KANF301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 8	ASP A 62 ASP A 287 ASN A 38 GLU A 129	None EOH A 348 ( 4.5A) None None	0.87A	4gkhF-3h4xA: undetectable	4gkhF-3h4xA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GKH_G_KANG301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 7	ASP A 62 ASP A 287 ASN A 38 GLU A 129	None EOH A 348 ( 4.5A) None None	0.86A	4gkhG-3h4xA: undetectable	4gkhG-3h4xA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GKH_J_KANJ301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 6	ASP A 62 ASP A 287 ASN A 38 GLU A 129	None EOH A 348 ( 4.5A) None None	0.91A	4gkhJ-3h4xA: undetectable	4gkhJ-3h4xA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GKH_K_KANK301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 8	ASP A 62 ASP A 287 ASN A 38 GLU A 129	None EOH A 348 ( 4.5A) None None	0.88A	4gkhC-3h4xA: undetectable 4gkhK-3h4xA: undetectable	4gkhC-3h4xA: 21.59 4gkhK-3h4xA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GKI_A_KANA301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 8	ASP A 62 ASP A 287 ASN A 38 GLU A 129	None EOH A 348 ( 4.5A) None None	0.86A	4gkiA-3h4xA: undetectable	4gkiA-3h4xA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GKI_C_KANC301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 8	ASP A 62 ASP A 287 ASN A 38 GLU A 129	None EOH A 348 ( 4.5A) None None	0.87A	4gkiC-3h4xA: undetectable	4gkiC-3h4xA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GKI_G_KANG301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 8	ASP A 62 ASP A 287 ASN A 38 GLU A 129	None EOH A 348 ( 4.5A) None None	0.87A	4gkiE-3h4xA: undetectable 4gkiG-3h4xA: undetectable	4gkiE-3h4xA: 21.59 4gkiG-3h4xA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P7N_A_GCSA702_1 (POLY-BETA-1,6-N-ACET YL-D-GLUCOSAMINE N-DEACETYLASE)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	3 / 3	ASP A 210 TYR A 247 TRP A 208	None None EOH A 347 (-3.5A)	1.32A	4p7nA-3h4xA: 6.4	4p7nA-3h4xA: 20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R1Z_A_AERA601_1 (CYP17A1 PROTEIN)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 9	ALA A 263 ILE A 194 ASP A 262 GLY A 237 ALA A 238	None None EOH A 348 ( 2.5A) None None	1.20A	4r1zA-3h4xA: undetectable	4r1zA-3h4xA: 22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X61_A_SAMA701_0 (PROTEIN ARGININE N-METHYLTRANSFERASE 5)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 12	LEU A 58 MET A 111 GLU A 60 LEU A 61 CYH A 107	None	1.17A	4x61A-3h4xA: 5.9	4x61A-3h4xA: 19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CU6_A_ACTA403_0 (CASEIN KINASE II SUBUNIT ALPHA)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 6	ILE A 194 VAL A 258 ASP A 260 ALA A 234	None None EOH A 358 (-4.1A) None	0.50A	5cu6A-3h4xA: undetectable	5cu6A-3h4xA: 22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5D4U_C_SAMC301_0 (UNCHARACTERIZED PROTEIN MJ0489)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 12	GLY A 35 LEU A 125 THR A 321 ILE A 284 GLY A 297	None	0.99A	5d4uC-3h4xA: undetectable	5d4uC-3h4xA: 23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5D4U_D_SAMD301_0 (UNCHARACTERIZED PROTEIN MJ0489)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 12	GLY A 35 LEU A 125 THR A 321 ILE A 284 GLY A 297	None	0.99A	5d4uD-3h4xA: undetectable	5d4uD-3h4xA: 23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EML_A_SAMA701_0 (PROTEIN ARGININE N-METHYLTRANSFERASE 5)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 12	LEU A 58 MET A 111 GLU A 60 LEU A 61 CYH A 107	None	1.11A	5emlA-3h4xA: 2.0	5emlA-3h4xA: 19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EWJ_D_QELD503_1 (NMDA GLUTAMATE RECEPTOR SUBUNIT GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2B)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 12	THR A 209 LEU A 217 ALA A 234 ILE A 194 THR A 164	None	1.49A	5ewjC-3h4xA: undetectable 5ewjD-3h4xA: undetectable	5ewjC-3h4xA: 21.34 5ewjD-3h4xA: 21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LF3_K_BO2K305_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-1)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 11	ALA A 320 THR A 321 ALA A 322 GLY A 261 ALA A 263	None	0.90A	5lf3K-3h4xA: undetectable 5lf3L-3h4xA: undetectable	5lf3K-3h4xA: 21.07 5lf3L-3h4xA: 20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LF3_Y_BO2Y305_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-1)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 11	ALA A 320 THR A 321 ALA A 322 GLY A 261 ALA A 263	None	0.90A	5lf3Y-3h4xA: undetectable 5lf3Z-3h4xA: undetectable	5lf3Y-3h4xA: 21.07 5lf3Z-3h4xA: 20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LF7_K_6V8K305_0 (PROTEASOME SUBUNIT BETA TYPE-1 PROTEASOME SUBUNIT BETA TYPE-5)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 11	ALA A 320 THR A 321 ALA A 322 GLY A 261 ALA A 263	None	0.74A	5lf7K-3h4xA: undetectable 5lf7L-3h4xA: undetectable	5lf7K-3h4xA: 21.07 5lf7L-3h4xA: 20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LF7_Y_6V8Y306_0 (PROTEASOME SUBUNIT BETA TYPE-1 PROTEASOME SUBUNIT BETA TYPE-5)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 11	ALA A 320 THR A 321 ALA A 322 GLY A 261 ALA A 263	None	0.76A	5lf7Y-3h4xA: undetectable 5lf7Z-3h4xA: undetectable	5lf7Y-3h4xA: 21.07 5lf7Z-3h4xA: 20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M5K_B_ADNB502_1 (ADENOSYLHOMOCYSTEINA SE)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 12	HIS A 216 ASP A 146 THR A 230 GLY A 215 PHE A 134	EOH A 353 (-3.9A) None None None None	1.37A	5m5kB-3h4xA: undetectable	5m5kB-3h4xA: 21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ND2_B_TA1B601_1 (TUBULIN BETA-2B CHAIN)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 12	VAL A 36 ALA A 51 SER A 54 PHE A 48 LEU A 126	None	1.32A	5nd2B-3h4xA: undetectable	5nd2B-3h4xA: 21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OSP_A_ACTA403_0 (CASEIN KINASE II SUBUNIT ALPHA)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 7	ILE A 194 VAL A 258 ASP A 260 ALA A 234	None None EOH A 358 (-4.1A) None	0.48A	5ospA-3h4xA: undetectable	5ospA-3h4xA: 22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OSR_A_ACTA402_0 (CASEIN KINASE II SUBUNIT ALPHA)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	4 / 7	ILE A 194 VAL A 258 ASP A 260 ALA A 234	None None EOH A 358 (-4.1A) None	0.45A	5osrA-3h4xA: undetectable	5osrA-3h4xA: 22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F3M_A_ADNA502_1 (-)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 12	HIS A 216 ASP A 146 LEU A 220 GLY A 215 PHE A 134	EOH A 353 (-3.9A) None None None None	1.41A	6f3mA-3h4xA: undetectable	6f3mA-3h4xA: 21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F3M_C_ADNC502_1 (-)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 12	HIS A 216 ASP A 146 LEU A 220 GLY A 215 PHE A 134	EOH A 353 (-3.9A) None None None None	1.41A	6f3mC-3h4xA: undetectable	6f3mC-3h4xA: 21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F3N_A_ADNA505_1 (-)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 12	HIS A 216 ASP A 146 LEU A 220 GLY A 215 PHE A 134	EOH A 353 (-3.9A) None None None None	1.45A	6f3nA-3h4xA: undetectable	6f3nA-3h4xA: 21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F3N_C_ADNC505_1 (-)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 12	HIS A 216 ASP A 146 LEU A 220 GLY A 215 PHE A 134	EOH A 353 (-3.9A) None None None None	1.44A	6f3nC-3h4xA: undetectable	6f3nC-3h4xA: 21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F3N_D_ADND506_1 (-)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 12	HIS A 216 ASP A 146 LEU A 220 GLY A 215 PHE A 134	EOH A 353 (-3.9A) None None None None	1.46A	6f3nD-3h4xA: undetectable	6f3nD-3h4xA: 21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNF_C_QPSC602_2 (-)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 12	ASP A 287 HIS A 289 GLU A 41 GLU A 129 GLY A 196	EOH A 348 ( 4.5A) None None None None	1.43A	6gnfC-3h4xA: undetectable	6gnfC-3h4xA: 23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNG_A_QPSA601_1 (-)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 12	THR A 209 GLY A 133 GLY A 237 ASP A 260 ASP A 62	None None None EOH A 358 (-4.1A) None	1.14A	6gngA-3h4xA: undetectable	6gngA-3h4xA: 23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HWD_Y_BO2Y301_0 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	3h4x	PHOSPHATIDYLINOSITOL -SPECIFIC PHOSPHOLIPASE C1 (Streptomyces antibioticus)	5 / 11	ALA A 320 THR A 321 ALA A 322 GLY A 261 ALA A 263	None	0.91A	6hwdY-3h4xA: undetectable 6hwdZ-3h4xA: undetectable	6hwdY-3h4xA: 15.70 6hwdZ-3h4xA: 14.48

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FM6_A_9CRA501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"ALA A 263;ALA A 288;TRP A 324;LEU A 267;ALA A 264","None;None;None;None;EOH A 348 ( 3.9A)","1.00A","1fm6A-3h4xA:undetectable","1fm6A-3h4xA:22.04"],["1MIC_A_DVAA6_0","GRAMICIDIN A","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",3,"ALA A 234;VAL A 257;TRP A 179","None","0.91A","1micA-3h4xA:undetectable;1micB-3h4xA:undetectable","1micA-3h4xA:5.68;1micB-3h4xA:5.68"],["2BXE_A_1FLA2002_1","SERUM ALBUMIN","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"ALA A 315;LEU A 312;LEU A 267;ALA A 263;SER A 270","None","1.04A","2bxeA-3h4xA:undetectable","2bxeA-3h4xA:20.37"],["2PLW_A_SAMA203_1","RIBOSOMAL RNA METHYLTRANSFERASE, PUTATIVE","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",3,"SER A  84;ASP A  50;ASP A 110","None","0.78A","2plwA-3h4xA:undetectable","2plwA-3h4xA:17.68"],["2YVL_C_SAMC604_1","HYPOTHETICAL PROTEIN","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"GLY A 141;GLU A 144;ASP A 146;TYR A 213","ACE A 368 (-3.3A);ACE A 368 (-3.1A);None;None","1.03A","2yvlC-3h4xA:undetectable","2yvlC-3h4xA:20.23"],["3B6H_B_MXDB551_1","PROSTACYCLIN SYNTHASE","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"TYR A 213;ALA A 214;LEU A 217;ALA A 170","None","0.93A","3b6hB-3h4xA:undetectable","3b6hB-3h4xA:21.16"],["3J6P_B_TA1B502_1","TUBULIN BETA CHAIN","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"VAL A  74;ASP A  62;LEU A 153;SER A  84;LEU A  59","None","1.15A","3j6pB-3h4xA:undetectable","3j6pB-3h4xA:21.84"],["3JUS_A_ECLA600_1","LANOSTEROL 14-ALPHA DEMETHYLASE","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"LEU A 125;GLY A 187;ALA A 156;ILE A 149","None;None;ACT A 361 ( 4.0A);None","0.80A","3jusA-3h4xA:undetectable","3jusA-3h4xA:23.04"],["3JUS_A_ECNA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"LEU A 125;GLY A 187;ALA A 156;ILE A 149","None;None;ACT A 361 ( 4.0A);None","0.80A","3jusA-3h4xA:undetectable","3jusA-3h4xA:23.04"],["3T3Z_A_9PLA501_1","CYTOCHROME P450 2E1","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"PHE A 145;LEU A 108;PHE A 191;LEU A  63","None","0.99A","3t3zA-3h4xA:undetectable","3t3zA-3h4xA:20.17"],["3WSJ_A_MK1A201_1","PROTEASE","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"LEU A 312;ALA A 322;ASP A 323;VAL A  34;LEU A 331","None","1.16A","3wsjA-3h4xA:undetectable","3wsjA-3h4xA:14.94"],["4AT0_A_ACTA1490_0","3-KETOSTEROID-DELTA4-5ALPHA-DEHYDROGENASE","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",3,"GLU A  41;TYR A  40;SER A  75","None","0.56A","4at0A-3h4xA:undetectable","4at0A-3h4xA:25.38"],["4CP3_B_RBTB1129_1","B-CELL LYMPHOMA 6 PROTEIN;B-CELL LYMPHOMA 6 PROTEIN","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ARG A  73;LEU A  63;ARG A 140;GLY A 106","None;None;GOL A 366 ( 3.6A);EOH A 349 (-3.7A)","0.88A","4cp3A-3h4xA:undetectable;4cp3B-3h4xA:undetectable","4cp3A-3h4xA:15.29;4cp3B-3h4xA:15.29"],["4EJW_A_SRYA2001_1","TRANSCRIPTIONAL REGULATOR TCAR","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"ALA A 234;GLU A 192;HIS A 236;TYR A 247;ARG A 246","None;None;EOH A 358 (-4.0A);None;None","1.37A","4ejwA-3h4xA:undetectable","4ejwA-3h4xA:18.34"],["4FEU_B_KANB301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ASP A  62;ASP A 287;ASN A  38;GLU A 129","None;EOH A 348 ( 4.5A);None;None","0.82A","4feuB-3h4xA:undetectable","4feuB-3h4xA:21.59"],["4FEU_D_KAND301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ASP A  62;ASP A 287;ASN A  38;GLU A 129","None;EOH A 348 ( 4.5A);None;None","0.90A","4feuD-3h4xA:undetectable","4feuD-3h4xA:21.59"],["4FEU_F_KANF301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ASP A  62;ASP A 287;ASN A  38;GLU A 129","None;EOH A 348 ( 4.5A);None;None","0.85A","4feuF-3h4xA:undetectable","4feuF-3h4xA:21.59"],["4FEV_B_KANB301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ASP A  62;ASP A 287;ASN A  38;GLU A 129","None;EOH A 348 ( 4.5A);None;None","0.89A","4fevB-3h4xA:undetectable","4fevB-3h4xA:21.59"],["4FEV_B_KANB301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ASP A  62;ASP A 287;GLU A  41;GLU A 129","None;EOH A 348 ( 4.5A);None;None","1.04A","4fevB-3h4xA:undetectable","4fevB-3h4xA:21.59"],["4FEV_D_KAND301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ASP A  62;ASP A 287;ASN A  38;GLU A 129","None;EOH A 348 ( 4.5A);None;None","0.87A","4fevD-3h4xA:undetectable","4fevD-3h4xA:21.59"],["4FEV_F_KANF301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ASP A  62;ASP A 287;ASN A  38;GLU A 129","None;EOH A 348 ( 4.5A);None;None","0.87A","4fevF-3h4xA:undetectable","4fevF-3h4xA:21.59"],["4FEW_B_KANB301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ASP A  62;ASP A 287;ASN A  38;GLU A 129","None;EOH A 348 ( 4.5A);None;None","0.90A","4fewB-3h4xA:undetectable","4fewB-3h4xA:21.59"],["4FEW_B_KANB301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ASP A  62;ASP A 287;GLU A  41;GLU A 129","None;EOH A 348 ( 4.5A);None;None","0.96A","4fewB-3h4xA:undetectable","4fewB-3h4xA:21.59"],["4FEW_D_KAND301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ASP A  62;ASP A 287;ASN A  38;GLU A 129","None;EOH A 348 ( 4.5A);None;None","0.87A","4fewD-3h4xA:undetectable","4fewD-3h4xA:21.59"],["4FEW_F_KANF301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ASP A  62;ASP A 287;ASN A  38;GLU A 129","None;EOH A 348 ( 4.5A);None;None","0.87A","4fewF-3h4xA:undetectable","4fewF-3h4xA:21.59"],["4FEX_B_KANB301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ASP A  62;ASP A 287;ASN A  38;GLU A 129","None;EOH A 348 ( 4.5A);None;None","0.91A","4fexB-3h4xA:undetectable","4fexB-3h4xA:21.59"],["4GKH_B_KANB301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ASP A  62;ASP A 287;ASN A  38;GLU A 129","None;EOH A 348 ( 4.5A);None;None","0.89A","4gkhB-3h4xA:undetectable","4gkhB-3h4xA:21.59"],["4GKH_D_KAND301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ASP A  62;ASP A 287;ASN A  38;GLU A 129","None;EOH A 348 ( 4.5A);None;None","0.89A","4gkhD-3h4xA:undetectable","4gkhD-3h4xA:21.59"],["4GKH_D_KAND301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ASP A  62;ASP A 287;GLU A  41;GLU A 129","None;EOH A 348 ( 4.5A);None;None","0.97A","4gkhD-3h4xA:undetectable","4gkhD-3h4xA:21.59"],["4GKH_F_KANF301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ASP A  62;ASP A 287;ASN A  38;GLU A 129","None;EOH A 348 ( 4.5A);None;None","0.87A","4gkhF-3h4xA:undetectable","4gkhF-3h4xA:21.59"],["4GKH_G_KANG301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ASP A  62;ASP A 287;ASN A  38;GLU A 129","None;EOH A 348 ( 4.5A);None;None","0.86A","4gkhG-3h4xA:undetectable","4gkhG-3h4xA:21.59"],["4GKH_J_KANJ301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ASP A  62;ASP A 287;ASN A  38;GLU A 129","None;EOH A 348 ( 4.5A);None;None","0.91A","4gkhJ-3h4xA:undetectable","4gkhJ-3h4xA:21.59"],["4GKH_K_KANK301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB;AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ASP A  62;ASP A 287;ASN A  38;GLU A 129","None;EOH A 348 ( 4.5A);None;None","0.88A","4gkhC-3h4xA:undetectable;4gkhK-3h4xA:undetectable","4gkhC-3h4xA:21.59;4gkhK-3h4xA:21.59"],["4GKI_A_KANA301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ASP A  62;ASP A 287;ASN A  38;GLU A 129","None;EOH A 348 ( 4.5A);None;None","0.86A","4gkiA-3h4xA:undetectable","4gkiA-3h4xA:21.59"],["4GKI_C_KANC301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ASP A  62;ASP A 287;ASN A  38;GLU A 129","None;EOH A 348 ( 4.5A);None;None","0.87A","4gkiC-3h4xA:undetectable","4gkiC-3h4xA:21.59"],["4GKI_G_KANG301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB;AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ASP A  62;ASP A 287;ASN A  38;GLU A 129","None;EOH A 348 ( 4.5A);None;None","0.87A","4gkiE-3h4xA:undetectable;4gkiG-3h4xA:undetectable","4gkiE-3h4xA:21.59;4gkiG-3h4xA:21.59"],["4P7N_A_GCSA702_1","POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE N-DEACETYLASE","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",3,"ASP A 210;TYR A 247;TRP A 208","None;None;EOH A 347 (-3.5A)","1.32A","4p7nA-3h4xA:6.4","4p7nA-3h4xA:20.42"],["4R1Z_A_AERA601_1","CYP17A1 PROTEIN","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"ALA A 263;ILE A 194;ASP A 262;GLY A 237;ALA A 238","None;None;EOH A 348 ( 2.5A);None;None","1.20A","4r1zA-3h4xA:undetectable","4r1zA-3h4xA:22.99"],["4X61_A_SAMA701_0","PROTEIN ARGININE N-METHYLTRANSFERASE 5","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"LEU A  58;MET A 111;GLU A  60;LEU A  61;CYH A 107","None","1.17A","4x61A-3h4xA:5.9","4x61A-3h4xA:19.45"],["5CU6_A_ACTA403_0","CASEIN KINASE II SUBUNIT ALPHA","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ILE A 194;VAL A 258;ASP A 260;ALA A 234","None;None;EOH A 358 (-4.1A);None","0.50A","5cu6A-3h4xA:undetectable","5cu6A-3h4xA:22.13"],["5D4U_C_SAMC301_0","UNCHARACTERIZED PROTEIN MJ0489","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"GLY A  35;LEU A 125;THR A 321;ILE A 284;GLY A 297","None","0.99A","5d4uC-3h4xA:undetectable","5d4uC-3h4xA:23.77"],["5D4U_D_SAMD301_0","UNCHARACTERIZED PROTEIN MJ0489","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"GLY A  35;LEU A 125;THR A 321;ILE A 284;GLY A 297","None","0.99A","5d4uD-3h4xA:undetectable","5d4uD-3h4xA:23.77"],["5EML_A_SAMA701_0","PROTEIN ARGININE N-METHYLTRANSFERASE 5","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"LEU A  58;MET A 111;GLU A  60;LEU A  61;CYH A 107","None","1.11A","5emlA-3h4xA:2.0","5emlA-3h4xA:19.45"],["5EWJ_D_QELD503_1","NMDA GLUTAMATE RECEPTOR SUBUNIT;GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2B","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"THR A 209;LEU A 217;ALA A 234;ILE A 194;THR A 164","None","1.49A","5ewjC-3h4xA:undetectable;5ewjD-3h4xA:undetectable","5ewjC-3h4xA:21.34;5ewjD-3h4xA:21.38"],["5LF3_K_BO2K305_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-1","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"ALA A 320;THR A 321;ALA A 322;GLY A 261;ALA A 263","None","0.90A","5lf3K-3h4xA:undetectable;5lf3L-3h4xA:undetectable","5lf3K-3h4xA:21.07;5lf3L-3h4xA:20.24"],["5LF3_Y_BO2Y305_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-1","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"ALA A 320;THR A 321;ALA A 322;GLY A 261;ALA A 263","None","0.90A","5lf3Y-3h4xA:undetectable;5lf3Z-3h4xA:undetectable","5lf3Y-3h4xA:21.07;5lf3Z-3h4xA:20.24"],["5LF7_K_6V8K305_0","PROTEASOME SUBUNIT BETA TYPE-1;PROTEASOME SUBUNIT BETA TYPE-5","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"ALA A 320;THR A 321;ALA A 322;GLY A 261;ALA A 263","None","0.74A","5lf7K-3h4xA:undetectable;5lf7L-3h4xA:undetectable","5lf7K-3h4xA:21.07;5lf7L-3h4xA:20.24"],["5LF7_Y_6V8Y306_0","PROTEASOME SUBUNIT BETA TYPE-1;PROTEASOME SUBUNIT BETA TYPE-5","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"ALA A 320;THR A 321;ALA A 322;GLY A 261;ALA A 263","None","0.76A","5lf7Y-3h4xA:undetectable;5lf7Z-3h4xA:undetectable","5lf7Y-3h4xA:21.07;5lf7Z-3h4xA:20.24"],["5M5K_B_ADNB502_1","ADENOSYLHOMOCYSTEINASE","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"HIS A 216;ASP A 146;THR A 230;GLY A 215;PHE A 134","EOH A 353 (-3.9A);None;None;None;None","1.37A","5m5kB-3h4xA:undetectable","5m5kB-3h4xA:21.32"],["5ND2_B_TA1B601_1","TUBULIN BETA-2B CHAIN","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"VAL A  36;ALA A  51;SER A  54;PHE A  48;LEU A 126","None","1.32A","5nd2B-3h4xA:undetectable","5nd2B-3h4xA:21.84"],["5OSP_A_ACTA403_0","CASEIN KINASE II SUBUNIT ALPHA","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ILE A 194;VAL A 258;ASP A 260;ALA A 234","None;None;EOH A 358 (-4.1A);None","0.48A","5ospA-3h4xA:undetectable","5ospA-3h4xA:22.50"],["5OSR_A_ACTA402_0","CASEIN KINASE II SUBUNIT ALPHA","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",4,"ILE A 194;VAL A 258;ASP A 260;ALA A 234","None;None;EOH A 358 (-4.1A);None","0.45A","5osrA-3h4xA:undetectable","5osrA-3h4xA:22.50"],["6F3M_A_ADNA502_1","-","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"HIS A 216;ASP A 146;LEU A 220;GLY A 215;PHE A 134","EOH A 353 (-3.9A);None;None;None;None","1.41A","6f3mA-3h4xA:undetectable","6f3mA-3h4xA:21.56"],["6F3M_C_ADNC502_1","-","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"HIS A 216;ASP A 146;LEU A 220;GLY A 215;PHE A 134","EOH A 353 (-3.9A);None;None;None;None","1.41A","6f3mC-3h4xA:undetectable","6f3mC-3h4xA:21.56"],["6F3N_A_ADNA505_1","-","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"HIS A 216;ASP A 146;LEU A 220;GLY A 215;PHE A 134","EOH A 353 (-3.9A);None;None;None;None","1.45A","6f3nA-3h4xA:undetectable","6f3nA-3h4xA:21.56"],["6F3N_C_ADNC505_1","-","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"HIS A 216;ASP A 146;LEU A 220;GLY A 215;PHE A 134","EOH A 353 (-3.9A);None;None;None;None","1.44A","6f3nC-3h4xA:undetectable","6f3nC-3h4xA:21.56"],["6F3N_D_ADND506_1","-","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"HIS A 216;ASP A 146;LEU A 220;GLY A 215;PHE A 134","EOH A 353 (-3.9A);None;None;None;None","1.46A","6f3nD-3h4xA:undetectable","6f3nD-3h4xA:21.56"],["6GNF_C_QPSC602_2","-","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"ASP A 287;HIS A 289;GLU A  41;GLU A 129;GLY A 196","EOH A 348 ( 4.5A);None;None;None;None","1.43A","6gnfC-3h4xA:undetectable","6gnfC-3h4xA:23.49"],["6GNG_A_QPSA601_1","-","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"THR A 209;GLY A 133;GLY A 237;ASP A 260;ASP A  62","None;None;None;EOH A 358 (-4.1A);None","1.14A","6gngA-3h4xA:undetectable","6gngA-3h4xA:23.37"],["6HWD_Y_BO2Y301_0","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","3h4x","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C1","Streptomyces antibioticus",5,"ALA A 320;THR A 321;ALA A 322;GLY A 261;ALA A 263","None","0.91A","6hwdY-3h4xA:undetectable;6hwdZ-3h4xA:undetectable","6hwdY-3h4xA:15.70;6hwdZ-3h4xA:14.48"]]