SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h4y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 3h4y PUTATIVE CHEMOTAXIS
PROTEIN
(Desulfovibrio
vulgaris) 		5 / 12 PRO A  30
ASN A 144
ILE A  26
LEU A  20
VAL A  17
 None
 1.00A 1r30A-3h4yA:
undetectable		 1r30A-3h4yA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 3h4y PUTATIVE CHEMOTAXIS
PROTEIN
(Desulfovibrio
vulgaris) 		5 / 12 PRO A  30
ASN A 144
ILE A  26
LEU A  20
VAL A  17
 None
 1.00A 1r30B-3h4yA:
undetectable		 1r30B-3h4yA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3h4y PUTATIVE CHEMOTAXIS
PROTEIN
(Desulfovibrio
vulgaris) 		4 / 5 SER A  60
VAL A 150
SER A  46
VAL A  48
 None
 1.26A 2j9cA-3h4yA:
undetectable
2j9cB-3h4yA:
undetectable
2j9cC-3h4yA:
undetectable		 2j9cA-3h4yA:
22.84
2j9cB-3h4yA:
22.84
2j9cC-3h4yA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 3h4y PUTATIVE CHEMOTAXIS
PROTEIN
(Desulfovibrio
vulgaris) 		5 / 10 ALA A  47
THR A  16
LEU A  20
MET A  23
VAL A  19
 None
 1.41A 2wuzA-3h4yA:
undetectable		 2wuzA-3h4yA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 3h4y PUTATIVE CHEMOTAXIS
PROTEIN
(Desulfovibrio
vulgaris) 		5 / 10 ALA A  47
THR A  16
LEU A  20
MET A  23
VAL A  19
 None
 1.41A 2wuzB-3h4yA:
undetectable		 2wuzB-3h4yA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_2
(PHOSPHOLIPASE A2)		 3h4y PUTATIVE CHEMOTAXIS
PROTEIN
(Desulfovibrio
vulgaris) 		5 / 9 VAL A  94
VAL A  91
GLY A  92
PRO A 118
GLY A 100
 None
 1.22A 3bjwG-3h4yA:
undetectable		 3bjwG-3h4yA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3h4y PUTATIVE CHEMOTAXIS
PROTEIN
(Desulfovibrio
vulgaris) 		5 / 12 MET A 109
ILE A  98
ILE A  13
VAL A 150
ARG A 103
 None
 1.00A 3fpjB-3h4yA:
undetectable		 3fpjB-3h4yA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA278_0
(UNIVERSAL STRESS
PROTEIN)		 3h4y PUTATIVE CHEMOTAXIS
PROTEIN
(Desulfovibrio
vulgaris) 		3 / 3 SER A 116
GLY A  50
SER A 119
 None
 0.41A 3loqA-3h4yA:
2.0		 3loqA-3h4yA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 3h4y PUTATIVE CHEMOTAXIS
PROTEIN
(Desulfovibrio
vulgaris) 		4 / 8 THR A  16
GLY A  31
PHE A 141
SER A   2
 None
 1.10A 3tzfB-3h4yA:
undetectable		 3tzfB-3h4yA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 3h4y PUTATIVE CHEMOTAXIS
PROTEIN
(Desulfovibrio
vulgaris) 		4 / 8 LEU A  71
CYH A  67
PHE A  63
PRO A  28
 None
 1.20A 4j7uD-3h4yA:
undetectable		 4j7uD-3h4yA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3h4y PUTATIVE CHEMOTAXIS
PROTEIN
(Desulfovibrio
vulgaris) 		4 / 6 ALA A  15
THR A  16
VAL A  19
VAL A  61
 None
 0.95A 5eckA-3h4yA:
undetectable		 5eckA-3h4yA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3h4y PUTATIVE CHEMOTAXIS
PROTEIN
(Desulfovibrio
vulgaris) 		4 / 8 ALA A  15
THR A  16
VAL A  19
VAL A  61
 None
 0.79A 5ecnD-3h4yA:
undetectable		 5ecnD-3h4yA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 3h4y PUTATIVE CHEMOTAXIS
PROTEIN
(Desulfovibrio
vulgaris) 		3 / 3 PRO A  33
ILE A  49
SER A   2
 None
 0.70A 5fsaA-3h4yA:
undetectable		 5fsaA-3h4yA:
14.88