SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h51'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0M_C_KLNC1499_1 (CYTOCHROME P450 3A4)	3h51	PUTATIVE CALCIUM/CALMODULIN DEPENDENT PROTEIN KINASE II ASSOCIATION DOMAIN (Xanthomonas campestris)	4 / 7	LEU A 51 PHE A 88 ILE A 150 GLY A 98	None	0.64A	2v0mC-3h51A: undetectable	2v0mC-3h51A: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WEK_A_DIFA1373_1 (ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2)	3h51	PUTATIVE CALCIUM/CALMODULIN DEPENDENT PROTEIN KINASE II ASSOCIATION DOMAIN (Xanthomonas campestris)	4 / 8	PHE A 91 VAL A 59 PHE A 44 ASN A 48	UNL A 175 ( 4.0A) None None None	1.08A	2wekA-3h51A: undetectable	2wekA-3h51A: 18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DGQ_A_EAAA211_1 (GLUTATHIONE S-TRANSFERASE P)	3h51	PUTATIVE CALCIUM/CALMODULIN DEPENDENT PROTEIN KINASE II ASSOCIATION DOMAIN (Xanthomonas campestris)	4 / 5	ARG A 103 ILE A 100 TYR A 119 THR A 120	None	1.28A	3dgqA-3h51A: undetectable	3dgqA-3h51A: 21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_A_ACTA310_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	3h51	PUTATIVE CALCIUM/CALMODULIN DEPENDENT PROTEIN KINASE II ASSOCIATION DOMAIN (Xanthomonas campestris)	3 / 3	GLU A 89 HIS A 57 ARG A 81	None	0.94A	5uunA-3h51A: undetectable	5uunA-3h51A: 20.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2V0M_C_KLNC1499_1","CYTOCHROME P450 3A4","3h51","PUTATIVE CALCIUM\/CALMODULIN DEPENDENT PROTEIN KINASE II ASSOCIATION DOMAIN","Xanthomonas campestris",4,"LEU A  51;PHE A  88;ILE A 150;GLY A  98","None","0.64A","2v0mC-3h51A:undetectable","2v0mC-3h51A:14.88"],["2WEK_A_DIFA1373_1","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","3h51","PUTATIVE CALCIUM\/CALMODULIN DEPENDENT PROTEIN KINASE II ASSOCIATION DOMAIN","Xanthomonas campestris",4,"PHE A  91;VAL A  59;PHE A  44;ASN A  48","UNL A 175 ( 4.0A);None;None;None","1.08A","2wekA-3h51A:undetectable","2wekA-3h51A:18.18"],["3DGQ_A_EAAA211_1","GLUTATHIONE S-TRANSFERASE P","3h51","PUTATIVE CALCIUM\/CALMODULIN DEPENDENT PROTEIN KINASE II ASSOCIATION DOMAIN","Xanthomonas campestris",4,"ARG A 103;ILE A 100;TYR A 119;THR A 120","None","1.28A","3dgqA-3h51A:undetectable","3dgqA-3h51A:21.03"],["5UUN_A_ACTA310_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN","3h51","PUTATIVE CALCIUM\/CALMODULIN DEPENDENT PROTEIN KINASE II ASSOCIATION DOMAIN","Xanthomonas campestris",3,"GLU A  89;HIS A  57;ARG A  81","None","0.94A","5uunA-3h51A:undetectable","5uunA-3h51A:20.00"]]