SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h5t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P91_A_SAMA1401_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE A)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	5 / 11	GLY A 72 GLY A 131 ILE A 134 TYR A 135 LEU A 347	None	0.96A	1p91A-3h5tA: 2.0	1p91A-3h5tA: 23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PCG_A_ESTA1_1 (ESTROGEN RECEPTOR)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	5 / 10	LEU A 195 ALA A 280 LEU A 300 LEU A 298 ILE A 192	None	1.28A	1pcgA-3h5tA: undetectable	1pcgA-3h5tA: 23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V55_J_CHDJ3060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE I CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 7	ILE A 147 LEU A 152 THR A 331 LEU A 332	None	0.73A	1v55A-3h5tA: undetectable 1v55J-3h5tA: undetectable	1v55A-3h5tA: 21.02 1v55J-3h5tA: 9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V55_W_CHDW4060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE I CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 8	ILE A 147 LEU A 152 THR A 331 LEU A 332	None	0.73A	1v55N-3h5tA: undetectable 1v55W-3h5tA: undetectable	1v55N-3h5tA: 21.02 1v55W-3h5tA: 9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIL_W_CHDW1060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 8	ILE A 147 LEU A 152 THR A 331 LEU A 332	None	0.74A	2eilN-3h5tA: undetectable 2eilW-3h5tA: undetectable	2eilN-3h5tA: 21.02 2eilW-3h5tA: 9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIN_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 8	ILE A 147 LEU A 152 THR A 331 LEU A 332	None	0.77A	2einA-3h5tA: undetectable 2einJ-3h5tA: undetectable	2einA-3h5tA: 21.02 2einJ-3h5tA: 9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IVU_A_ZD6A3015_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET PRECURSOR)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	3 / 3	ALA A 228 GLY A 193 SER A 196	None	0.59A	2ivuA-3h5tA: undetectable	2ivuA-3h5tA: 20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J2P_C_SC2C1289_1 (FICOLIN-2)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 6	ARG A 224 ASP A 85 SER A 88 SER A 136	None	0.99A	2j2pA-3h5tA: undetectable 2j2pC-3h5tA: undetectable	2j2pA-3h5tA: 20.11 2j2pC-3h5tA: 20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J2P_F_SC2F1289_1 (FICOLIN-2)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 6	ARG A 224 ASP A 85 SER A 88 SER A 136	None	1.01A	2j2pD-3h5tA: undetectable 2j2pF-3h5tA: undetectable	2j2pD-3h5tA: 20.11 2j2pF-3h5tA: 20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCD_A_RAPA138_1 (OUTER MEMBRANE PROTEIN MIP)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	5 / 11	TYR A 135 ASP A 158 GLN A 97 VAL A 95 VAL A 345	None	1.15A	2vcdA-3h5tA: undetectable	2vcdA-3h5tA: 16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABK_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 8	ILE A 147 LEU A 152 THR A 331 LEU A 332	None	0.77A	3abkA-3h5tA: undetectable 3abkJ-3h5tA: undetectable	3abkA-3h5tA: 21.02 3abkJ-3h5tA: 9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABM_W_CHDW1060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 8	ILE A 147 LEU A 152 THR A 331 LEU A 332	None	0.76A	3abmN-3h5tA: undetectable 3abmW-3h5tA: undetectable	3abmN-3h5tA: 21.02 3abmW-3h5tA: 9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG3_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 7	ILE A 147 LEU A 152 THR A 331 LEU A 332	None	0.74A	3ag3A-3h5tA: undetectable 3ag3J-3h5tA: undetectable	3ag3A-3h5tA: 21.02 3ag3J-3h5tA: 9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG3_W_CHDW1059_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 8	ILE A 147 LEU A 152 THR A 331 LEU A 332	None	0.76A	3ag3N-3h5tA: undetectable 3ag3W-3h5tA: undetectable	3ag3N-3h5tA: 21.02 3ag3W-3h5tA: 9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASN_W_CHDW1059_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 8	ILE A 147 LEU A 152 THR A 331 LEU A 332	None	0.75A	3asnN-3h5tA: undetectable 3asnW-3h5tA: undetectable	3asnN-3h5tA: 21.02 3asnW-3h5tA: 9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASO_W_CHDW1059_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 8	ILE A 147 LEU A 152 THR A 331 LEU A 332	None	0.75A	3asoN-3h5tA: undetectable 3asoW-3h5tA: undetectable	3asoN-3h5tA: 21.02 3asoW-3h5tA: 9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDW_A_RITA100_2 (PROTEASE)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	5 / 9	ALA A 127 ILE A 147 GLY A 131 ILE A 71 ILE A 107	None	1.07A	3ndwB-3h5tA: undetectable	3ndwB-3h5tA: 14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ROD_D_NCAD302_0 (NICOTINAMIDE N-METHYLTRANSFERASE)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 7	TYR A 81 ASP A 277 ALA A 278 ASP A 304	None	1.01A	3rodD-3h5tA: undetectable	3rodD-3h5tA: 22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SI7_D_ACTD4_0 (CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 5	LEU A 40 LEU A 19 GLY A 20 THR A 25	None	0.66A	3si7C-3h5tA: undetectable 3si7D-3h5tA: undetectable	3si7C-3h5tA: 18.80 3si7D-3h5tA: 18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_B_IL2B901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	5 / 12	LEU A 263 VAL A 283 PHE A 281 THR A 301 THR A 316	None	1.25A	3sp9B-3h5tA: undetectable	3sp9B-3h5tA: 20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UA5_A_06XA502_1 (CYTOCHROME P450 2B6)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	5 / 11	LEU A 287 GLU A 264 GLU A 257 PHE A 256 VAL A 290	None	1.44A	3ua5A-3h5tA: undetectable	3ua5A-3h5tA: 21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VAS_B_ADNB401_2 (PUTATIVE ADENOSINE KINASE)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 5	LEU A 19 ALA A 17 MET A 51 THR A 47	None	1.40A	3vasB-3h5tA: 3.5	3vasB-3h5tA: 20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DX5_B_MIYB1103_1 (ACRIFLAVINE RESISTANCE PROTEIN B)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	5 / 12	PHE A 326 GLY A 325 ASN A 321 ASP A 90 ALA A 96	None	1.19A	4dx5B-3h5tA: undetectable	4dx5B-3h5tA: 16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKV_C_AERC601_2 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 6	LEU A 273 ASP A 277 VAL A 258 ALA A 259	None	1.10A	4nkvC-3h5tA: undetectable	4nkvC-3h5tA: 22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B1A_J_CHDJ102_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 7	ILE A 147 LEU A 152 THR A 331 LEU A 332	None	0.75A	5b1aA-3h5tA: undetectable 5b1aJ-3h5tA: undetectable	5b1aA-3h5tA: 21.02 5b1aJ-3h5tA: 9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B3S_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 7	ILE A 147 LEU A 152 THR A 331 LEU A 332	None	0.81A	5b3sA-3h5tA: undetectable 5b3sJ-3h5tA: undetectable	5b3sA-3h5tA: 21.02 5b3sJ-3h5tA: 9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5H2U_A_1N1A501_1 (PROTEIN-TYROSINE KINASE 6)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	6 / 12	LEU A 287 ALA A 294 LEU A 314 THR A 356 GLY A 282 GLY A 302	None	1.46A	5h2uA-3h5tA: undetectable	5h2uA-3h5tA: 23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KPC_A_SAMA401_1 (PAVINE N-METHYLTRANSFERASE)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 5	PHE A 91 ASN A 173 GLN A 319 ASP A 223	None	0.86A	5kpcA-3h5tA: undetectable	5kpcA-3h5tA: 18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WGQ_A_ESTA601_1 (ESTROGEN RECEPTOR)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	5 / 9	ALA A 98 GLU A 330 LEU A 333 GLY A 72 LEU A 104	None	1.47A	5wgqA-3h5tA: undetectable	5wgqA-3h5tA: 11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XDQ_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 7	ILE A 147 LEU A 152 THR A 331 LEU A 332	None	0.78A	5xdqN-3h5tA: undetectable 5xdqW-3h5tA: undetectable	5xdqN-3h5tA: 21.02 5xdqW-3h5tA: 9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XDX_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT VIIA-HEART)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 7	ILE A 147 LEU A 152 THR A 331 LEU A 332	None	0.77A	5xdxA-3h5tA: undetectable 5xdxJ-3h5tA: undetectable	5xdxA-3h5tA: 21.02 5xdxJ-3h5tA: 9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XOO_B_ADNB503_1 (GLYCOSAMINOGLYCAN XYLOSYLKINASE)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 5	LEU A 213 VAL A 208 GLU A 246 LEU A 199	None	1.06A	5xooB-3h5tA: undetectable	5xooB-3h5tA: 12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCP_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 7	ILE A 147 LEU A 152 THR A 331 LEU A 332	None	0.79A	5zcpA-3h5tA: undetectable 5zcpJ-3h5tA: undetectable	5zcpA-3h5tA: 21.02 5zcpJ-3h5tA: 9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCP_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 8	ILE A 147 LEU A 152 THR A 331 LEU A 332	None	0.79A	5zcpN-3h5tA: undetectable 5zcpW-3h5tA: undetectable	5zcpN-3h5tA: 21.02 5zcpW-3h5tA: 9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCQ_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 7	ILE A 147 LEU A 152 THR A 331 LEU A 332	None	0.77A	5zcqA-3h5tA: undetectable 5zcqJ-3h5tA: undetectable	5zcqA-3h5tA: 21.02 5zcqJ-3h5tA: 9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_D_AQ4D602_0 (CYTOCHROME P450 1A1)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	5 / 12	ILE A 192 SER A 299 GLY A 188 ALA A 187 ASP A 186	None	1.05A	6dwnD-3h5tA: undetectable	6dwnD-3h5tA: 12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6G1P_B_ACTB403_0 (ADP-RIBOSYLHYDROLASE LIKE 2)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	3 / 3	PHE A 256 ARG A 252 GLN A 253	None	1.13A	6g1pB-3h5tA: undetectable	6g1pB-3h5tA: 24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NMF_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 7	ILE A 147 LEU A 152 THR A 331 LEU A 332	None	0.85A	6nmfA-3h5tA: undetectable 6nmfJ-3h5tA: undetectable	6nmfA-3h5tA: 21.02 6nmfJ-3h5tA: 9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NMP_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3h5t	TRANSCRIPTIONAL REGULATOR, LACI FAMILY (Corynebacterium glutamicum)	4 / 5	ILE A 147 LEU A 152 THR A 331 LEU A 332	None	0.84A	6nmpN-3h5tA: undetectable 6nmpW-3h5tA: undetectable	6nmpN-3h5tA: 21.02 6nmpW-3h5tA: 9.56

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1P91_A_SAMA1401_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE A","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",5,"GLY A  72;GLY A 131;ILE A 134;TYR A 135;LEU A 347","None","0.96A","1p91A-3h5tA:2.0","1p91A-3h5tA:23.06"],["1PCG_A_ESTA1_1","ESTROGEN RECEPTOR","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",5,"LEU A 195;ALA A 280;LEU A 300;LEU A 298;ILE A 192","None","1.28A","1pcgA-3h5tA:undetectable","1pcgA-3h5tA:23.20"],["1V55_J_CHDJ3060_0","CYTOCHROME C OXIDASE POLYPEPTIDE I;CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"ILE A 147;LEU A 152;THR A 331;LEU A 332","None","0.73A","1v55A-3h5tA:undetectable;1v55J-3h5tA:undetectable","1v55A-3h5tA:21.02;1v55J-3h5tA:9.56"],["1V55_W_CHDW4060_0","CYTOCHROME C OXIDASE POLYPEPTIDE I;CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"ILE A 147;LEU A 152;THR A 331;LEU A 332","None","0.73A","1v55N-3h5tA:undetectable;1v55W-3h5tA:undetectable","1v55N-3h5tA:21.02;1v55W-3h5tA:9.56"],["2EIL_W_CHDW1060_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"ILE A 147;LEU A 152;THR A 331;LEU A 332","None","0.74A","2eilN-3h5tA:undetectable;2eilW-3h5tA:undetectable","2eilN-3h5tA:21.02;2eilW-3h5tA:9.56"],["2EIN_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"ILE A 147;LEU A 152;THR A 331;LEU A 332","None","0.77A","2einA-3h5tA:undetectable;2einJ-3h5tA:undetectable","2einA-3h5tA:21.02;2einJ-3h5tA:9.56"],["2IVU_A_ZD6A3015_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET PRECURSOR","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",3,"ALA A 228;GLY A 193;SER A 196","None","0.59A","2ivuA-3h5tA:undetectable","2ivuA-3h5tA:20.63"],["2J2P_C_SC2C1289_1","FICOLIN-2;FICOLIN-2","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"ARG A 224;ASP A  85;SER A  88;SER A 136","None","0.99A","2j2pA-3h5tA:undetectable;2j2pC-3h5tA:undetectable","2j2pA-3h5tA:20.11;2j2pC-3h5tA:20.11"],["2J2P_F_SC2F1289_1","FICOLIN-2;FICOLIN-2","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"ARG A 224;ASP A  85;SER A  88;SER A 136","None","1.01A","2j2pD-3h5tA:undetectable;2j2pF-3h5tA:undetectable","2j2pD-3h5tA:20.11;2j2pF-3h5tA:20.11"],["2VCD_A_RAPA138_1","OUTER MEMBRANE PROTEIN MIP","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",5,"TYR A 135;ASP A 158;GLN A  97;VAL A  95;VAL A 345","None","1.15A","2vcdA-3h5tA:undetectable","2vcdA-3h5tA:16.76"],["3ABK_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"ILE A 147;LEU A 152;THR A 331;LEU A 332","None","0.77A","3abkA-3h5tA:undetectable;3abkJ-3h5tA:undetectable","3abkA-3h5tA:21.02;3abkJ-3h5tA:9.56"],["3ABM_W_CHDW1060_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"ILE A 147;LEU A 152;THR A 331;LEU A 332","None","0.76A","3abmN-3h5tA:undetectable;3abmW-3h5tA:undetectable","3abmN-3h5tA:21.02;3abmW-3h5tA:9.56"],["3AG3_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"ILE A 147;LEU A 152;THR A 331;LEU A 332","None","0.74A","3ag3A-3h5tA:undetectable;3ag3J-3h5tA:undetectable","3ag3A-3h5tA:21.02;3ag3J-3h5tA:9.56"],["3AG3_W_CHDW1059_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"ILE A 147;LEU A 152;THR A 331;LEU A 332","None","0.76A","3ag3N-3h5tA:undetectable;3ag3W-3h5tA:undetectable","3ag3N-3h5tA:21.02;3ag3W-3h5tA:9.56"],["3ASN_W_CHDW1059_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"ILE A 147;LEU A 152;THR A 331;LEU A 332","None","0.75A","3asnN-3h5tA:undetectable;3asnW-3h5tA:undetectable","3asnN-3h5tA:21.02;3asnW-3h5tA:9.56"],["3ASO_W_CHDW1059_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"ILE A 147;LEU A 152;THR A 331;LEU A 332","None","0.75A","3asoN-3h5tA:undetectable;3asoW-3h5tA:undetectable","3asoN-3h5tA:21.02;3asoW-3h5tA:9.56"],["3NDW_A_RITA100_2","PROTEASE;PROTEASE","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",5,"ALA A 127;ILE A 147;GLY A 131;ILE A  71;ILE A 107","None","1.07A","3ndwB-3h5tA:undetectable","3ndwB-3h5tA:14.81"],["3ROD_D_NCAD302_0","NICOTINAMIDE N-METHYLTRANSFERASE","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"TYR A  81;ASP A 277;ALA A 278;ASP A 304","None","1.01A","3rodD-3h5tA:undetectable","3rodD-3h5tA:22.05"],["3SI7_D_ACTD4_0","CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"LEU A  40;LEU A  19;GLY A  20;THR A  25","None","0.66A","3si7C-3h5tA:undetectable;3si7D-3h5tA:undetectable","3si7C-3h5tA:18.80;3si7D-3h5tA:18.80"],["3SP9_B_IL2B901_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",5,"LEU A 263;VAL A 283;PHE A 281;THR A 301;THR A 316","None","1.25A","3sp9B-3h5tA:undetectable","3sp9B-3h5tA:20.65"],["3UA5_A_06XA502_1","CYTOCHROME P450 2B6","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",5,"LEU A 287;GLU A 264;GLU A 257;PHE A 256;VAL A 290","None","1.44A","3ua5A-3h5tA:undetectable","3ua5A-3h5tA:21.86"],["3VAS_B_ADNB401_2","PUTATIVE ADENOSINE KINASE","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"LEU A  19;ALA A  17;MET A  51;THR A  47","None","1.40A","3vasB-3h5tA:3.5","3vasB-3h5tA:20.53"],["4DX5_B_MIYB1103_1","ACRIFLAVINE RESISTANCE PROTEIN B","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",5,"PHE A 326;GLY A 325;ASN A 321;ASP A  90;ALA A  96","None","1.19A","4dx5B-3h5tA:undetectable","4dx5B-3h5tA:16.35"],["4NKV_C_AERC601_2","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"LEU A 273;ASP A 277;VAL A 258;ALA A 259","None","1.10A","4nkvC-3h5tA:undetectable","4nkvC-3h5tA:22.74"],["5B1A_J_CHDJ102_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"ILE A 147;LEU A 152;THR A 331;LEU A 332","None","0.75A","5b1aA-3h5tA:undetectable;5b1aJ-3h5tA:undetectable","5b1aA-3h5tA:21.02;5b1aJ-3h5tA:9.56"],["5B3S_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"ILE A 147;LEU A 152;THR A 331;LEU A 332","None","0.81A","5b3sA-3h5tA:undetectable;5b3sJ-3h5tA:undetectable","5b3sA-3h5tA:21.02;5b3sJ-3h5tA:9.56"],["5H2U_A_1N1A501_1","PROTEIN-TYROSINE KINASE 6","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",6,"LEU A 287;ALA A 294;LEU A 314;THR A 356;GLY A 282;GLY A 302","None","1.46A","5h2uA-3h5tA:undetectable","5h2uA-3h5tA:23.91"],["5KPC_A_SAMA401_1","PAVINE N-METHYLTRANSFERASE","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"PHE A  91;ASN A 173;GLN A 319;ASP A 223","None","0.86A","5kpcA-3h5tA:undetectable","5kpcA-3h5tA:18.76"],["5WGQ_A_ESTA601_1","ESTROGEN RECEPTOR","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",5,"ALA A  98;GLU A 330;LEU A 333;GLY A  72;LEU A 104","None","1.47A","5wgqA-3h5tA:undetectable","5wgqA-3h5tA:11.38"],["5XDQ_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"ILE A 147;LEU A 152;THR A 331;LEU A 332","None","0.78A","5xdqN-3h5tA:undetectable;5xdqW-3h5tA:undetectable","5xdqN-3h5tA:21.02;5xdqW-3h5tA:9.56"],["5XDX_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT VIIA-HEART","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"ILE A 147;LEU A 152;THR A 331;LEU A 332","None","0.77A","5xdxA-3h5tA:undetectable;5xdxJ-3h5tA:undetectable","5xdxA-3h5tA:21.02;5xdxJ-3h5tA:9.56"],["5XOO_B_ADNB503_1","GLYCOSAMINOGLYCAN XYLOSYLKINASE","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"LEU A 213;VAL A 208;GLU A 246;LEU A 199","None","1.06A","5xooB-3h5tA:undetectable","5xooB-3h5tA:12.29"],["5ZCP_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"ILE A 147;LEU A 152;THR A 331;LEU A 332","None","0.79A","5zcpA-3h5tA:undetectable;5zcpJ-3h5tA:undetectable","5zcpA-3h5tA:21.02;5zcpJ-3h5tA:9.56"],["5ZCP_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"ILE A 147;LEU A 152;THR A 331;LEU A 332","None","0.79A","5zcpN-3h5tA:undetectable;5zcpW-3h5tA:undetectable","5zcpN-3h5tA:21.02;5zcpW-3h5tA:9.56"],["5ZCQ_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"ILE A 147;LEU A 152;THR A 331;LEU A 332","None","0.77A","5zcqA-3h5tA:undetectable;5zcqJ-3h5tA:undetectable","5zcqA-3h5tA:21.02;5zcqJ-3h5tA:9.56"],["6DWN_D_AQ4D602_0","CYTOCHROME P450 1A1","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",5,"ILE A 192;SER A 299;GLY A 188;ALA A 187;ASP A 186","None","1.05A","6dwnD-3h5tA:undetectable","6dwnD-3h5tA:12.18"],["6G1P_B_ACTB403_0","ADP-RIBOSYLHYDROLASE LIKE 2","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",3,"PHE A 256;ARG A 252;GLN A 253","None","1.13A","6g1pB-3h5tA:undetectable","6g1pB-3h5tA:24.81"],["6NMF_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"ILE A 147;LEU A 152;THR A 331;LEU A 332","None","0.85A","6nmfA-3h5tA:undetectable;6nmfJ-3h5tA:undetectable","6nmfA-3h5tA:21.02;6nmfJ-3h5tA:9.56"],["6NMP_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3h5t","TRANSCRIPTIONAL REGULATOR, LACI FAMILY","Corynebacterium glutamicum",4,"ILE A 147;LEU A 152;THR A 331;LEU A 332","None","0.84A","6nmpN-3h5tA:undetectable;6nmpW-3h5tA:undetectable","6nmpN-3h5tA:21.02;6nmpW-3h5tA:9.56"]]