SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h74'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 4 THR A 211
LEU A 215
VAL A 218
LEU A 222
 GOL  A 283 ( 4.7A)
None
None
None
 0.49A 1fbmD-3h74A:
undetectable		 1fbmD-3h74A:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 5 THR A 211
LEU A 215
VAL A 218
LEU A 222
 GOL  A 283 ( 4.7A)
None
None
None
 0.74A 1fbmE-3h74A:
undetectable		 1fbmE-3h74A:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMK_A_H4BA1427_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		5 / 12 VAL A   6
LEU A  18
SER A  11
LEU A  40
HIS A 279
 None
 1.46A 1mmkA-3h74A:
undetectable		 1mmkA-3h74A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU3_A_MRCA993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		5 / 12 GLY A  15
ASN A 209
ASP A   9
HIS A  43
VAL A  13
 None
 1.49A 1qu3A-3h74A:
undetectable		 1qu3A-3h74A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		5 / 12 GLY A 206
GLY A 210
ASN A 209
ALA A 260
ASP A 255
 None
 1.02A 2bm9F-3h74A:
undetectable		 2bm9F-3h74A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 SER A  17
ASP A   9
SER A  19
GLN A 257
 None
 0.94A 2cmlC-3h74A:
undetectable		 2cmlC-3h74A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		5 / 12 THR A  91
ASP A   9
HIS A 279
ALA A 125
VAL A 107
 None
 1.43A 2g72A-3h74A:
undetectable		 2g72A-3h74A:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 LEU A  77
TRP A 239
ASP A 213
THR A 214
 None
 1.18A 2y69C-3h74A:
undetectable
2y69N-3h74A:
undetectable
2y69P-3h74A:
undetectable		 2y69C-3h74A:
21.50
2y69N-3h74A:
21.65
2y69P-3h74A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YY8_B_SAMB500_0
(UPF0106 PROTEIN
PH0461)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		5 / 11 LEU A 215
GLY A 210
VAL A 259
ILE A 219
ALA A 216
 None
 1.02A 2yy8A-3h74A:
undetectable
2yy8B-3h74A:
undetectable		 2yy8A-3h74A:
23.55
2yy8B-3h74A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 TRP A 239
ASP A 213
THR A 214
LEU A  77
 None
 1.15A 3ablA-3h74A:
undetectable
3ablC-3h74A:
undetectable
3ablP-3h74A:
undetectable		 3ablA-3h74A:
21.65
3ablC-3h74A:
21.50
3ablP-3h74A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 LEU A  77
TRP A 239
ASP A 213
THR A 214
 None
 1.17A 3ablC-3h74A:
undetectable
3ablN-3h74A:
undetectable
3ablP-3h74A:
undetectable		 3ablC-3h74A:
21.50
3ablN-3h74A:
21.65
3ablP-3h74A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 TRP A 239
ASP A 213
THR A 214
LEU A  77
 None
 1.11A 3abmA-3h74A:
undetectable
3abmC-3h74A:
undetectable
3abmP-3h74A:
undetectable		 3abmA-3h74A:
21.65
3abmC-3h74A:
21.50
3abmP-3h74A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 LEU A  77
TRP A 239
ASP A 213
THR A 214
 None
 1.18A 3asnC-3h74A:
undetectable
3asnN-3h74A:
undetectable
3asnP-3h74A:
undetectable		 3asnC-3h74A:
21.50
3asnN-3h74A:
21.65
3asnP-3h74A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 TRP A 239
ASP A 213
THR A 214
LEU A  77
 None
 1.19A 3asoA-3h74A:
undetectable
3asoC-3h74A:
undetectable
3asoP-3h74A:
undetectable		 3asoA-3h74A:
21.65
3asoC-3h74A:
21.50
3asoP-3h74A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		5 / 12 THR A 214
ALA A 217
LEU A  25
LEU A  22
LEU A 264
 None
 1.07A 3hm1A-3h74A:
undetectable		 3hm1A-3h74A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB800_0
(GLUTAMATE RECEPTOR 2)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		5 / 10 SER A  20
SER A  11
LEU A  10
ASP A   9
GLY A 258
 None
 1.07A 3lsfB-3h74A:
0.0
3lsfE-3h74A:
0.0		 3lsfB-3h74A:
20.74
3lsfE-3h74A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE800_0
(GLUTAMATE RECEPTOR 2)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		5 / 10 GLY A 258
SER A  20
SER A  11
LEU A  10
ASP A   9
 None
 1.07A 3lsfB-3h74A:
0.0
3lsfE-3h74A:
0.0		 3lsfB-3h74A:
20.74
3lsfE-3h74A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 SER A  20
SER A  11
LEU A  10
ASP A   9
 None
 0.88A 3lsfH-3h74A:
undetectable		 3lsfH-3h74A:
20.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MBH_A_PXLA400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		5 / 11 ASP A   9
LEU A  40
TYR A  80
VAL A 107
ASP A 213
 None
 0.96A 3mbhA-3h74A:
33.7		 3mbhA-3h74A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MBH_A_PXLA400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		6 / 11 ASP A   9
SER A  11
LEU A  40
HIS A  43
THR A  44
ASP A 213
 None
 0.78A 3mbhA-3h74A:
33.7		 3mbhA-3h74A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MBH_A_PXLA400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		5 / 11 ASP A   9
TYR A  80
VAL A 107
TYR A 115
ASP A 213
 None
 0.91A 3mbhA-3h74A:
33.7		 3mbhA-3h74A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MBH_B_PXLB400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		7 / 12 ASP A   9
SER A  11
SER A  17
LEU A  40
HIS A  43
THR A  44
ASP A 213
 None
 0.77A 3mbhB-3h74A:
33.4		 3mbhB-3h74A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MBH_B_PXLB400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		7 / 12 ASP A   9
SER A  11
SER A  17
LEU A  40
HIS A  43
VAL A 107
ASP A 213
 None
 0.98A 3mbhB-3h74A:
33.4		 3mbhB-3h74A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MBH_B_PXLB400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		6 / 12 ASP A   9
SER A  17
LEU A  40
TYR A  80
VAL A 107
ASP A 213
 None
 0.89A 3mbhB-3h74A:
33.4		 3mbhB-3h74A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MBH_B_PXLB400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		5 / 12 ASP A   9
TYR A  80
VAL A 107
TYR A 115
ASP A 213
 None
 0.90A 3mbhB-3h74A:
33.4		 3mbhB-3h74A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MBH_C_PXLC400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		8 / 12 ASP A   9
SER A  11
SER A  17
LEU A  40
HIS A  43
THR A  44
VAL A 107
ASP A 213
 None
 0.95A 3mbhC-3h74A:
33.4		 3mbhC-3h74A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MBH_C_PXLC400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		6 / 12 ASP A   9
SER A  17
LEU A  40
TYR A  80
VAL A 107
ASP A 213
 None
 0.91A 3mbhC-3h74A:
33.4		 3mbhC-3h74A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MBH_C_PXLC400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		5 / 12 ASP A   9
TYR A  80
VAL A 107
TYR A 115
ASP A 213
 None
 0.91A 3mbhC-3h74A:
33.4		 3mbhC-3h74A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MBH_D_PXLD400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		7 / 12 ASP A   9
SER A  11
SER A  17
LEU A  40
HIS A  43
THR A  44
ASP A 213
 None
 0.77A 3mbhD-3h74A:
33.7		 3mbhD-3h74A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MBH_D_PXLD400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		7 / 12 ASP A   9
SER A  11
SER A  17
LEU A  40
HIS A  43
VAL A 107
ASP A 213
 None
 0.98A 3mbhD-3h74A:
33.7		 3mbhD-3h74A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MBH_D_PXLD400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		7 / 12 ASP A   9
SER A  17
LEU A  40
HIS A  43
TYR A  80
VAL A 107
ASP A 213
 None
 1.02A 3mbhD-3h74A:
33.7		 3mbhD-3h74A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MBH_D_PXLD400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		5 / 12 ASP A   9
TYR A  80
VAL A 107
TYR A 115
ASP A 213
 None
 0.91A 3mbhD-3h74A:
33.7		 3mbhD-3h74A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MBH_E_PXLE400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		8 / 12 ASP A   9
SER A  11
SER A  17
LEU A  40
HIS A  43
THR A  44
VAL A 107
ASP A 213
 None
 0.94A 3mbhE-3h74A:
33.7		 3mbhE-3h74A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MBH_E_PXLE400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		6 / 12 ASP A   9
SER A  17
LEU A  40
TYR A  80
VAL A 107
ASP A 213
 None
 0.93A 3mbhE-3h74A:
33.7		 3mbhE-3h74A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MBH_F_PXLF400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		5 / 11 ASP A   9
LEU A  40
TYR A  80
VAL A 107
ASP A 213
 None
 0.94A 3mbhF-3h74A:
33.6		 3mbhF-3h74A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MBH_F_PXLF400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		6 / 11 ASP A   9
SER A  11
LEU A  40
HIS A  43
THR A  44
ASP A 213
 None
 0.81A 3mbhF-3h74A:
33.6		 3mbhF-3h74A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MBH_F_PXLF400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		6 / 11 ASP A   9
SER A  11
LEU A  40
HIS A  43
VAL A 107
ASP A 213
 None
 1.04A 3mbhF-3h74A:
33.6		 3mbhF-3h74A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MBH_F_PXLF400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		5 / 11 ASP A   9
TYR A  80
VAL A 107
TYR A 115
ASP A 213
 None
 0.89A 3mbhF-3h74A:
33.6		 3mbhF-3h74A:
33.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_A_GJZA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 6 LEU A 240
ILE A 219
ALA A 216
THR A 177
 GOL  A 283 ( 4.2A)
None
None
None
 1.03A 3mdrA-3h74A:
undetectable		 3mdrA-3h74A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		5 / 11 LEU A 108
ASP A 105
LEU A 137
GLY A 212
ASP A 213
 None
SO4  A 281 ( 4.5A)
None
SO4  A 281 (-3.4A)
None
 1.44A 3sfuC-3h74A:
undetectable		 3sfuC-3h74A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 TRP A 239
ASP A 213
THR A 214
LEU A  77
 None
 1.08A 3wg7A-3h74A:
undetectable
3wg7C-3h74A:
undetectable
3wg7P-3h74A:
undetectable		 3wg7A-3h74A:
21.65
3wg7C-3h74A:
21.50
3wg7P-3h74A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 TRP A 239
ASP A 213
THR A 214
LEU A  77
 None
 1.06A 3x2qA-3h74A:
undetectable
3x2qC-3h74A:
undetectable
3x2qP-3h74A:
undetectable		 3x2qA-3h74A:
21.65
3x2qC-3h74A:
21.50
3x2qP-3h74A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 LEU A  77
TRP A 239
ASP A 213
THR A 214
 None
 1.15A 3x2qC-3h74A:
undetectable
3x2qN-3h74A:
1.5
3x2qP-3h74A:
undetectable		 3x2qC-3h74A:
21.50
3x2qN-3h74A:
21.65
3x2qP-3h74A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 7 VAL A 135
ILE A 136
LEU A 157
LEU A 161
 None
 0.88A 4l1wA-3h74A:
undetectable		 4l1wA-3h74A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		5 / 12 LEU A  77
VAL A 103
LEU A 137
VAL A 135
THR A 232
 None
 0.98A 4m2wA-3h74A:
undetectable		 4m2wA-3h74A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_A_MRVA1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 7 TYR A  93
LEU A  22
THR A  26
THR A  37
 None
 1.02A 4mbsA-3h74A:
undetectable		 4mbsA-3h74A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 SER A  11
SER A  45
ASP A 255
ASP A 254
 None
 1.44A 4qb9D-3h74A:
undetectable		 4qb9D-3h74A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		5 / 10 LEU A 264
LEU A 265
GLY A 262
ALA A 217
ILE A 268
 None
 1.16A 4xj7C-3h74A:
undetectable
4xj7D-3h74A:
undetectable		 4xj7C-3h74A:
24.61
4xj7D-3h74A:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 7 VAL A 135
ILE A 136
LEU A 157
LEU A 161
 None
 0.95A 4xo7A-3h74A:
undetectable		 4xo7A-3h74A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 TRP A 239
ASP A 213
THR A 214
LEU A  77
 None
 1.10A 5b1aA-3h74A:
undetectable
5b1aC-3h74A:
undetectable
5b1aP-3h74A:
undetectable		 5b1aA-3h74A:
21.65
5b1aC-3h74A:
21.50
5b1aP-3h74A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 TRP A 239
ASP A 213
THR A 214
LEU A  77
 None
 1.13A 5b3sA-3h74A:
undetectable
5b3sC-3h74A:
undetectable
5b3sP-3h74A:
undetectable		 5b3sA-3h74A:
21.65
5b3sC-3h74A:
21.50
5b3sP-3h74A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		3 / 3 ASP A 213
VAL A   6
LEU A  25
 None
 0.60A 5e5jB-3h74A:
undetectable		 5e5jB-3h74A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 TRP A 239
ASP A 213
THR A 214
LEU A  77
 None
 1.07A 5wauA-3h74A:
undetectable
5wauC-3h74A:
undetectable
5wauc-3h74A:
undetectable		 5wauA-3h74A:
21.65
5wauC-3h74A:
21.50
5wauc-3h74A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 TRP A 239
ASP A 213
THR A 214
LEU A  77
 None
 1.11A 5x19A-3h74A:
undetectable
5x19C-3h74A:
undetectable
5x19P-3h74A:
undetectable		 5x19A-3h74A:
21.65
5x19C-3h74A:
21.50
5x19P-3h74A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 TRP A 239
ASP A 213
THR A 214
LEU A  77
 None
 1.09A 5xdqA-3h74A:
undetectable
5xdqC-3h74A:
undetectable
5xdqP-3h74A:
undetectable		 5xdqA-3h74A:
21.65
5xdqC-3h74A:
21.50
5xdqP-3h74A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 LEU A  77
TRP A 239
ASP A 213
THR A 214
 None
 1.15A 5xdxC-3h74A:
undetectable
5xdxN-3h74A:
undetectable
5xdxP-3h74A:
undetectable		 5xdxC-3h74A:
20.92
5xdxN-3h74A:
21.65
5xdxP-3h74A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 TRP A 239
ASP A 213
THR A 214
LEU A  77
 None
 1.09A 5z84A-3h74A:
undetectable
5z84C-3h74A:
undetectable
5z84P-3h74A:
undetectable		 5z84A-3h74A:
21.65
5z84C-3h74A:
21.50
5z84P-3h74A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 TRP A 239
ASP A 213
THR A 214
LEU A  77
 None
 1.08A 5z85A-3h74A:
undetectable
5z85C-3h74A:
undetectable
5z85P-3h74A:
undetectable		 5z85A-3h74A:
21.65
5z85C-3h74A:
21.50
5z85P-3h74A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 TRP A 239
ASP A 213
THR A 214
LEU A  77
 None
 1.08A 5z86A-3h74A:
undetectable
5z86C-3h74A:
undetectable
5z86P-3h74A:
undetectable		 5z86A-3h74A:
21.65
5z86C-3h74A:
21.50
5z86P-3h74A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 LEU A  77
TRP A 239
ASP A 213
THR A 214
 None
 1.16A 5z86C-3h74A:
undetectable
5z86N-3h74A:
undetectable
5z86P-3h74A:
undetectable		 5z86C-3h74A:
21.50
5z86N-3h74A:
21.65
5z86P-3h74A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 TRP A 239
ASP A 213
THR A 214
LEU A  77
 None
 1.08A 5zcoA-3h74A:
undetectable
5zcoC-3h74A:
undetectable
5zcoP-3h74A:
undetectable		 5zcoA-3h74A:
21.65
5zcoC-3h74A:
21.50
5zcoP-3h74A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 TRP A 239
ASP A 213
THR A 214
LEU A  77
 None
 1.11A 5zcpA-3h74A:
undetectable
5zcpC-3h74A:
undetectable
5zcpP-3h74A:
undetectable		 5zcpA-3h74A:
21.65
5zcpC-3h74A:
21.50
5zcpP-3h74A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 LEU A  77
TRP A 239
ASP A 213
THR A 214
 None
 1.14A 5zcpC-3h74A:
undetectable
5zcpN-3h74A:
undetectable
5zcpP-3h74A:
undetectable		 5zcpC-3h74A:
21.50
5zcpN-3h74A:
21.65
5zcpP-3h74A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 TRP A 239
ASP A 213
THR A 214
LEU A  77
 None
 1.11A 5zcqA-3h74A:
undetectable
5zcqC-3h74A:
undetectable
5zcqP-3h74A:
undetectable		 5zcqA-3h74A:
21.65
5zcqC-3h74A:
21.50
5zcqP-3h74A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h74 PYRIDOXAL KINASE
(Lactobacillus
plantarum) 		4 / 8 LEU A  77
TRP A 239
ASP A 213
THR A 214
 None
 1.15A 6nknC-3h74A:
undetectable
6nknN-3h74A:
undetectable
6nknP-3h74A:
undetectable		 6nknC-3h74A:
21.50
6nknN-3h74A:
21.65
6nknP-3h74A:
21.50