SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h75'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		4 / 4 ARG A 225
ALA A 253
ALA A 285
GLU A 281
 None
 1.16A 1e7bA-3h75A:
undetectable		 1e7bA-3h75A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		4 / 4 ARG A 225
ALA A 253
ALA A 285
GLU A 281
 None
 1.12A 1e7bB-3h75A:
undetectable		 1e7bB-3h75A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		5 / 11 VAL A  54
LEU A  81
LEU A 306
THR A  52
TYR A 369
 None
 1.15A 1mmtA-3h75A:
undetectable		 1mmtA-3h75A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		4 / 4 LEU A 104
LEU A 129
SER A 130
LEU A 137
 None
 1.19A 1ya3A-3h75A:
undetectable		 1ya3A-3h75A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2002_1
(SERUM ALBUMIN)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		5 / 10 ALA A 253
ALA A 256
LEU A 236
SER A 292
LEU A 291
 None
 1.16A 2bxeA-3h75A:
undetectable		 2bxeA-3h75A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1216_1
(LIPOPROTEIN LPPX)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		4 / 5 LEU A  57
ILE A 126
LEU A 129
SER A 130
 None
 0.85A 2byoA-3h75A:
undetectable		 2byoA-3h75A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OK6_H_BEZH2001_0
(AROMATIC AMINE
DEHYDROGENASE, LARGE
SUBUNIT
AROMATIC AMINE
DEHYDROGENASE, SMALL
SUBUNIT)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		5 / 10 PHE A 299
GLN A 348
GLY A 346
LEU A 342
PHE A  73
 None
 1.38A 2ok6A-3h75A:
undetectable
2ok6H-3h75A:
undetectable		 2ok6A-3h75A:
22.07
2ok6H-3h75A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		4 / 7 LEU A 190
VAL A 192
THR A 193
VAL A 122
 None
None
SO4  A 400 ( 3.9A)
None
 0.90A 2qblA-3h75A:
undetectable		 2qblA-3h75A:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		4 / 7 ARG A  92
GLU A 222
ALA A 195
ALA A 196
 SO4  A 400 (-2.9A)
None
SO4  A 400 (-3.4A)
None
 1.01A 2zgwA-3h75A:
undetectable		 2zgwA-3h75A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		3 / 3 LEU A 373
TRP A 304
GLY A 303
 None
 0.79A 3l35A-3h75A:
undetectable
3l35H-3h75A:
undetectable		 3l35A-3h75A:
9.45
3l35H-3h75A:
4.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		3 / 3 LEU A 373
TRP A 304
GLY A 303
 None
 0.78A 3l35B-3h75A:
undetectable
3l35K-3h75A:
undetectable		 3l35B-3h75A:
9.45
3l35K-3h75A:
4.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		4 / 7 PRO A 324
ILE A 151
LEU A 127
ASN A 118
 None
 0.94A 3p50A-3h75A:
undetectable		 3p50A-3h75A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		4 / 7 PRO A 324
ILE A 151
LEU A 127
ASN A 118
 None
 0.94A 3p50B-3h75A:
undetectable		 3p50B-3h75A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		4 / 7 PRO A 324
ILE A 151
LEU A 127
ASN A 118
 None
 0.95A 3p50C-3h75A:
undetectable		 3p50C-3h75A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_D_PFLD320_1
(GLR4197 PROTEIN)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		4 / 7 PRO A 324
ILE A 151
LEU A 127
ASN A 118
 None
 0.94A 3p50D-3h75A:
undetectable		 3p50D-3h75A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		4 / 7 PRO A 324
ILE A 151
LEU A 127
ASN A 118
 None
 0.94A 3p50E-3h75A:
undetectable		 3p50E-3h75A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPW_A_NCAA412_0
(OLD YELLOW ENZYME
2.6 (OYE2.6), NADPH
DEHYDROGENASE)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		5 / 9 THR A  97
ALA A 101
ILE A 126
PHE A  56
ASN A  58
 None
 1.43A 3upwA-3h75A:
undetectable		 3upwA-3h75A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		4 / 5 LEU A 185
ALA A 256
THR A 242
PHE A 273
 None
 1.41A 3vasB-3h75A:
2.5		 3vasB-3h75A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		4 / 6 THR A  63
ASN A  61
GLY A  60
ILE A  87
 None
 1.04A 3w9tF-3h75A:
undetectable		 3w9tF-3h75A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		6 / 12 LEU A  81
GLY A 322
LEU A 306
HIS A 310
ASP A 311
GLY A 302
 None
 1.16A 4blvA-3h75A:
2.4		 4blvA-3h75A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_A_0LAA602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		4 / 5 LEU A 342
LEU A 373
THR A 300
TRP A 304
 None
 1.25A 4do3A-3h75A:
undetectable		 4do3A-3h75A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA602_1
(SERUM ALBUMIN)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		5 / 9 ALA A 253
ALA A 256
LEU A 185
SER A 292
LEU A 291
 None
 1.25A 4or0A-3h75A:
undetectable		 4or0A-3h75A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4USW_A_ACTA1470_0
(ADENYLATE CYCLASE
TYPE 10)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		4 / 6 LEU A 169
LEU A 291
VAL A 293
PHE A 273
 None
 1.25A 4uswA-3h75A:
undetectable		 4uswA-3h75A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJQ_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		5 / 11 SER A 274
SER A 188
GLU A 200
ASN A 277
GLY A 162
 None
None
None
GOL  A 402 (-2.9A)
None
 1.34A 4zjqA-3h75A:
0.2		 4zjqA-3h75A:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		4 / 4 LEU A 170
ILE A 182
PRO A 211
LEU A 207
 None
 1.19A 5eb3A-3h75A:
2.8		 5eb3A-3h75A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA303_1
(CHITOSANASE)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		4 / 5 ASP A 157
VAL A 276
GLY A 297
ALA A 296
 None
 1.00A 5hwaA-3h75A:
undetectable		 5hwaA-3h75A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IM2_A_BEZA401_0
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		5 / 12 PHE A 105
ILE A 126
LEU A 104
LEU A  88
VAL A  55
 None
 0.92A 5im2A-3h75A:
undetectable		 5im2A-3h75A:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_1
(METHYLTRANSFERASE)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		4 / 7 GLY A  60
PHE A  66
SER A  71
GLU A  64
 None
GOL  A 402 ( 4.0A)
None
None
 1.12A 5n5dB-3h75A:
2.8		 5n5dB-3h75A:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA502_1
(CYTOCHROME P450 2C9)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		4 / 6 PRO A 267
GLY A 268
THR A 269
LYS A 172
 None
 0.96A 5xxiA-3h75A:
undetectable		 5xxiA-3h75A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YVN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 3h75 PERIPLASMIC
SUGAR-BINDING DOMAIN
PROTEIN
(Pseudomonas
protegens) 		4 / 6 LEU A 334
GLN A 338
LEU A 376
LEU A 373
 None
 1.17A 5yvnA-3h75A:
undetectable		 5yvnA-3h75A:
25.21