SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h79'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_A_ACTA501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 3h79 THIOREDOXIN-LIKE
PROTEIN
(Trypanosoma
cruzi) 		4 / 7 ARG A  97
VAL A  38
ILE A  76
TYR A  99
 None
 0.90A 2yfbA-3h79A:
undetectable		 2yfbA-3h79A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_B_ACTB501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 3h79 THIOREDOXIN-LIKE
PROTEIN
(Trypanosoma
cruzi) 		4 / 6 ARG A  97
VAL A  38
ILE A  76
TYR A  99
 None
 0.88A 2yfbB-3h79A:
undetectable		 2yfbB-3h79A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 3h79 THIOREDOXIN-LIKE
PROTEIN
(Trypanosoma
cruzi) 		3 / 3 ASN A 126
LEU A  58
PHE A 124
 None
 0.61A 4dajB-3h79A:
undetectable		 4dajB-3h79A:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_C_08JC602_1
(CYTOCHROME P450 3A4)		 3h79 THIOREDOXIN-LIKE
PROTEIN
(Trypanosoma
cruzi) 		4 / 7 SER A  15
ALA A  73
ILE A  28
LEU A  20
 None
 0.84A 5te8C-3h79A:
undetectable		 5te8C-3h79A:
17.26