SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h7a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		5 / 10 ILE A  21
ALA A  22
ALA A  19
ALA A  34
ILE A 183
 ILE  A  21 ( 0.6A)
ALA  A  22 ( 0.0A)
ALA  A  19 ( 0.0A)
ALA  A  34 ( 0.0A)
ILE  A 183 ( 0.7A)
 1.07A 2aclC-3h7aA:
undetectable		 2aclC-3h7aA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		4 / 8 ILE A 135
PHE A 137
THR A  70
LEU A  73
 ILE  A 135 ( 0.6A)
PHE  A 137 ( 1.3A)
THR  A  70 ( 0.8A)
LEU  A  73 ( 0.5A)
 0.89A 3abkA-3h7aA:
undetectable
3abkJ-3h7aA:
undetectable		 3abkA-3h7aA:
18.89
3abkJ-3h7aA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		4 / 8 ILE A 135
PHE A 137
THR A  70
LEU A  73
 ILE  A 135 ( 0.6A)
PHE  A 137 ( 1.3A)
THR  A  70 ( 0.8A)
LEU  A  73 ( 0.5A)
 0.82A 3ablN-3h7aA:
undetectable
3ablW-3h7aA:
undetectable		 3ablN-3h7aA:
18.89
3ablW-3h7aA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		4 / 8 ILE A 135
PHE A 137
THR A  70
LEU A  73
 ILE  A 135 ( 0.6A)
PHE  A 137 ( 1.3A)
THR  A  70 ( 0.8A)
LEU  A  73 ( 0.5A)
 0.86A 3abmN-3h7aA:
undetectable
3abmW-3h7aA:
undetectable		 3abmN-3h7aA:
18.89
3abmW-3h7aA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		4 / 8 ILE A 135
PHE A 137
THR A  70
LEU A  73
 ILE  A 135 ( 0.6A)
PHE  A 137 ( 1.3A)
THR  A  70 ( 0.8A)
LEU  A  73 ( 0.5A)
 0.89A 3ag3N-3h7aA:
undetectable
3ag3W-3h7aA:
undetectable		 3ag3N-3h7aA:
18.89
3ag3W-3h7aA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		4 / 8 ILE A 135
PHE A 137
THR A  70
LEU A  73
 ILE  A 135 ( 0.6A)
PHE  A 137 ( 1.3A)
THR  A  70 ( 0.8A)
LEU  A  73 ( 0.5A)
 0.92A 3asoN-3h7aA:
1.0
3asoW-3h7aA:
undetectable		 3asoN-3h7aA:
18.89
3asoW-3h7aA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		5 / 10 ILE A  21
ALA A  22
ALA A  19
ALA A  34
ILE A 183
 ILE  A  21 ( 0.6A)
ALA  A  22 ( 0.0A)
ALA  A  19 ( 0.0A)
ALA  A  34 ( 0.0A)
ILE  A 183 ( 0.7A)
 1.09A 3falA-3h7aA:
undetectable		 3falA-3h7aA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		5 / 10 ILE A  21
ALA A  22
ALA A  19
ALA A  34
ILE A 183
 ILE  A  21 ( 0.6A)
ALA  A  22 ( 0.0A)
ALA  A  19 ( 0.0A)
ALA  A  34 ( 0.0A)
ILE  A 183 ( 0.7A)
 1.03A 3falC-3h7aA:
undetectable		 3falC-3h7aA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		5 / 12 GLY A  12
ALA A  13
ASP A  62
ALA A  63
VAL A  89
 GLY  A  12 ( 0.0A)
ALA  A  13 ( 0.0A)
ASP  A  62 ( 0.6A)
ALA  A  63 ( 0.0A)
VAL  A  89 ( 0.6A)
 1.18A 3nvkF-3h7aA:
undetectable
3nvkJ-3h7aA:
8.0		 3nvkF-3h7aA:
23.30
3nvkJ-3h7aA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		5 / 12 GLY A  12
GLY A  14
ASP A  62
ARG A  64
VAL A  89
 GLY  A  12 ( 0.0A)
GLY  A  14 ( 0.0A)
ASP  A  62 ( 0.6A)
ARG  A  64 ( 0.6A)
VAL  A  89 ( 0.6A)
 0.98A 3o7wA-3h7aA:
undetectable		 3o7wA-3h7aA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		3 / 3 THR A  70
ASN A  74
GLU A 122
 THR  A  70 ( 0.8A)
ASN  A  74 ( 0.6A)
GLU  A 122 ( 0.6A)
 0.69A 3v4tA-3h7aA:
undetectable
3v4tC-3h7aA:
0.3		 3v4tA-3h7aA:
20.29
3v4tC-3h7aA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_D_15UD402_1
(PROTHROMBIN)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		5 / 12 ASP A  62
ALA A  63
GLU A 110
ALA A 112
VAL A  89
 ASP  A  62 ( 0.6A)
ALA  A  63 ( 0.0A)
GLU  A 110 ( 0.6A)
ALA  A 112 ( 0.0A)
VAL  A  89 ( 0.6A)
 1.01A 4hfpD-3h7aA:
undetectable		 4hfpD-3h7aA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		5 / 9 PRO A 214
VAL A 217
ALA A 218
TYR A 221
GLY A  18
 PRO  A 214 ( 1.1A)
VAL  A 217 ( 0.6A)
ALA  A 218 ( 0.0A)
TYR  A 221 ( 1.3A)
GLY  A  18 ( 0.0A)
 1.05A 4mmbA-3h7aA:
undetectable		 4mmbA-3h7aA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		5 / 12 PRO A 214
VAL A 217
ALA A 218
TYR A 221
GLY A  18
 PRO  A 214 ( 1.1A)
VAL  A 217 ( 0.6A)
ALA  A 218 ( 0.0A)
TYR  A 221 ( 1.3A)
GLY  A  18 ( 0.0A)
 0.89A 4mmdB-3h7aA:
undetectable		 4mmdB-3h7aA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		5 / 12 ILE A  86
GLY A  18
ALA A  19
ALA A  26
ILE A  56
 ILE  A  86 ( 0.6A)
GLY  A  18 ( 0.0A)
ALA  A  19 ( 0.0A)
ALA  A  26 ( 0.0A)
ILE  A  56 ( 0.7A)
 0.95A 4nkxB-3h7aA:
undetectable		 4nkxB-3h7aA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		4 / 7 ILE A 135
PHE A 137
THR A  70
LEU A  73
 ILE  A 135 ( 0.6A)
PHE  A 137 ( 1.3A)
THR  A  70 ( 0.8A)
LEU  A  73 ( 0.5A)
 0.86A 5b1bN-3h7aA:
undetectable
5b1bW-3h7aA:
undetectable		 5b1bN-3h7aA:
18.89
5b1bW-3h7aA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		4 / 7 ILE A 135
PHE A 137
THR A  70
LEU A  73
 ILE  A 135 ( 0.6A)
PHE  A 137 ( 1.3A)
THR  A  70 ( 0.8A)
LEU  A  73 ( 0.5A)
 0.88A 5b3sN-3h7aA:
undetectable
5b3sW-3h7aA:
undetectable		 5b3sN-3h7aA:
18.89
5b3sW-3h7aA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		4 / 6 PHE A 158
ALA A 162
HIS A 180
LEU A 160
 PHE  A 158 ( 1.3A)
ALA  A 162 ( 0.0A)
HIS  A 180 ( 1.0A)
LEU  A 160 ( 0.6A)
 1.25A 5dzkB-3h7aA:
3.1
5dzkP-3h7aA:
undetectable		 5dzkB-3h7aA:
23.99
5dzkP-3h7aA:
0.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		4 / 7 ILE A 135
PHE A 137
THR A  70
LEU A  73
 ILE  A 135 ( 0.6A)
PHE  A 137 ( 1.3A)
THR  A  70 ( 0.8A)
LEU  A  73 ( 0.5A)
 0.91A 5iy5N-3h7aA:
undetectable
5iy5W-3h7aA:
undetectable		 5iy5N-3h7aA:
18.89
5iy5W-3h7aA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_D_SAMD501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		5 / 10 LEU A  61
ILE A  11
GLY A  12
GLY A  14
ALA A  63
 LEU  A  61 ( 0.6A)
ILE  A  11 ( 0.6A)
GLY  A  12 ( 0.0A)
GLY  A  14 ( 0.0A)
ALA  A  63 ( 0.0A)
 0.95A 5o96C-3h7aA:
3.6
5o96D-3h7aA:
3.6		 5o96C-3h7aA:
20.66
5o96D-3h7aA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		4 / 7 THR A  85
LEU A  73
VAL A  69
VAL A  89
 THR  A  85 ( 0.8A)
LEU  A  73 ( 0.5A)
VAL  A  69 ( 0.6A)
VAL  A  89 ( 0.6A)
 1.05A 5wk9A-3h7aA:
undetectable		 5wk9A-3h7aA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_1
(CYTOCHROME P450 2C9)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		5 / 12 VAL A  69
MET A 167
GLY A 116
ALA A 115
LEU A  61
 VAL  A  69 ( 0.6A)
MET  A 167 ( 0.0A)
GLY  A 116 ( 0.0A)
ALA  A 115 ( 0.0A)
LEU  A  61 ( 0.6A)
 1.06A 5x23A-3h7aA:
undetectable		 5x23A-3h7aA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_1
(CYTOCHROME P450 2C9)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		5 / 12 VAL A  69
MET A 167
GLY A 116
ALA A 115
LEU A  61
 VAL  A  69 ( 0.6A)
MET  A 167 ( 0.0A)
GLY  A 116 ( 0.0A)
ALA  A 115 ( 0.0A)
LEU  A  61 ( 0.6A)
 1.01A 5xxiA-3h7aA:
undetectable		 5xxiA-3h7aA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3h7a SHORT CHAIN
DEHYDROGENASE
(Rhodopseudomonas
palustris) 		4 / 8 ILE A 135
PHE A 137
THR A  70
LEU A  73
 ILE  A 135 ( 0.6A)
PHE  A 137 ( 1.3A)
THR  A  70 ( 0.8A)
LEU  A  73 ( 0.5A)
 0.89A 5zcpN-3h7aA:
undetectable
5zcpW-3h7aA:
undetectable		 5zcpN-3h7aA:
18.89
5zcpW-3h7aA:
11.90