SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h7k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		4 / 7 ASP A  94
TRP A 125
TYR A 133
ARG A  32
 AGT  A 366 ( 3.0A)
AGT  A 366 (-3.9A)
None
None
 1.47A 1cebB-3h7kA:
undetectable		 1cebB-3h7kA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_2
(POL POLYPROTEIN)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		3 / 3 ASP A 226
VAL A 168
PRO A  16
 AGT  A 366 ( 2.2A)
None
None
 0.74A 2avvA-3h7kA:
undetectable		 2avvA-3h7kA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		5 / 12 THR A 221
GLY A 223
GLY A 217
VAL A 176
HIS A 224
 AGT  A 366 ( 4.5A)
None
NA  A 387 (-3.7A)
None
AGT  A 366 ( 4.1A)
 1.16A 2b25B-3h7kA:
undetectable		 2b25B-3h7kA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		4 / 6 LEU A 203
ILE A 118
ARG A  93
GLY A 164
 None
None
None
AGT  A 366 ( 3.5A)
 0.82A 2du8A-3h7kA:
undetectable		 2du8A-3h7kA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		4 / 6 LEU A 203
ILE A 118
ARG A  93
GLY A 164
 None
None
None
AGT  A 366 ( 3.5A)
 0.79A 2du8B-3h7kA:
undetectable		 2du8B-3h7kA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		5 / 12 ASN A 123
GLY A 131
GLY A 127
TYR A 133
ASN A  35
 None
NA  A 385 ( 4.5A)
None
None
AGT  A 366 ( 4.8A)
 1.23A 2zw9A-3h7kA:
undetectable		 2zw9A-3h7kA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		4 / 4 ARG A 306
ASP A 244
ASP A 247
PRO A 248
 None
 0.46A 3fgrB-3h7kA:
undetectable		 3fgrB-3h7kA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		5 / 12 LEU A 161
ILE A 166
CYH A 174
LEU A 203
SER A 191
 None
 1.21A 3ko0A-3h7kA:
undetectable
3ko0B-3h7kA:
undetectable
3ko0C-3h7kA:
undetectable
3ko0D-3h7kA:
undetectable		 3ko0A-3h7kA:
14.13
3ko0B-3h7kA:
14.13
3ko0C-3h7kA:
14.13
3ko0D-3h7kA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		5 / 12 SER A 191
LEU A 161
ILE A 166
CYH A 174
LEU A 203
 None
 1.22A 3ko0G-3h7kA:
undetectable
3ko0H-3h7kA:
undetectable
3ko0I-3h7kA:
undetectable
3ko0J-3h7kA:
undetectable		 3ko0G-3h7kA:
14.13
3ko0H-3h7kA:
14.13
3ko0I-3h7kA:
14.13
3ko0J-3h7kA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		5 / 11 SER A 191
LEU A 203
LEU A 161
ILE A 166
CYH A 174
 None
 1.23A 3ko0A-3h7kA:
undetectable
3ko0B-3h7kA:
undetectable
3ko0I-3h7kA:
undetectable
3ko0J-3h7kA:
undetectable		 3ko0A-3h7kA:
14.13
3ko0B-3h7kA:
14.13
3ko0I-3h7kA:
14.13
3ko0J-3h7kA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		5 / 12 LEU A 203
LEU A 161
ILE A 166
CYH A 174
SER A 191
 None
 1.22A 3ko0K-3h7kA:
undetectable
3ko0L-3h7kA:
undetectable
3ko0M-3h7kA:
undetectable
3ko0N-3h7kA:
undetectable		 3ko0K-3h7kA:
14.13
3ko0L-3h7kA:
14.13
3ko0M-3h7kA:
14.13
3ko0N-3h7kA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		3 / 3 GLY A 164
ASP A  94
ASP A  89
 AGT  A 366 ( 3.5A)
AGT  A 366 ( 3.0A)
None
 0.47A 3ou7C-3h7kA:
undetectable		 3ou7C-3h7kA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		5 / 12 PHE A  92
ILE A  54
ALA A  51
VAL A  82
MET A  85
 None
 1.16A 3s79A-3h7kA:
undetectable		 3s79A-3h7kA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		4 / 6 ILE A 209
TRP A 241
ILE A 278
MET A 228
 None
 1.37A 3weoA-3h7kA:
undetectable		 3weoA-3h7kA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		4 / 8 ASP A  94
CYH A 180
GLU A 179
ASP A 226
 AGT  A 366 ( 3.0A)
None
None
AGT  A 366 ( 2.2A)
 1.05A 4gkhB-3h7kA:
undetectable		 4gkhB-3h7kA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		4 / 8 ASP A  94
CYH A 180
GLU A 179
ASP A 226
 AGT  A 366 ( 3.0A)
None
None
AGT  A 366 ( 2.2A)
 0.90A 4gkhD-3h7kA:
undetectable		 4gkhD-3h7kA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		4 / 8 ASP A  94
CYH A 180
GLU A 179
ASP A 226
 AGT  A 366 ( 3.0A)
None
None
AGT  A 366 ( 2.2A)
 1.02A 4gkiC-3h7kA:
undetectable		 4gkiC-3h7kA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4II8_A_010A210_0
(LYSOZYME C)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		4 / 7 GLU A 179
ASP A 218
ASN A 227
ILE A 225
 None
 1.13A 4ii8A-3h7kA:
undetectable		 4ii8A-3h7kA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		3 / 3 ASP A  89
TYR A 133
TRP A  36
 None
 1.22A 4p7nA-3h7kA:
undetectable		 4p7nA-3h7kA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAH_A_LNRA600_1
(PHENYLALANINE
HYDROXYLASE)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		4 / 6 LEU A 339
HIS A 365
HIS A 167
GLU A  18
 None
AGT  A 366 ( 4.8A)
None
None
 1.06A 4pahA-3h7kA:
undetectable		 4pahA-3h7kA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		4 / 8 HIS A  22
ASN A 318
HIS A 365
THR A 368
 None
None
AGT  A 366 ( 4.8A)
None
 1.31A 5db5A-3h7kA:
undetectable
5db5B-3h7kA:
undetectable		 5db5A-3h7kA:
21.59
5db5B-3h7kA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		5 / 12 PHE A  92
ILE A  54
ALA A  51
VAL A  82
MET A  85
 None
 1.17A 5jkvA-3h7kA:
undetectable		 5jkvA-3h7kA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_B_FUAB1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		4 / 5 ILE A 100
LEU A 161
HIS A 167
VAL A 168
 None
 1.14A 5jmnB-3h7kA:
undetectable		 5jmnB-3h7kA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B2W_A_AG2A401_1
(PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		7 / 10 ASP A  89
TRP A  91
ASP A  94
TRP A 125
ASP A 220
THR A 221
HIS A 224
 None
AGT  A 366 ( 3.6A)
AGT  A 366 ( 3.0A)
AGT  A 366 (-3.9A)
AGT  A 366 (-3.7A)
AGT  A 366 ( 4.5A)
AGT  A 366 ( 4.1A)
 0.76A 6b2wA-3h7kA:
44.9		 6b2wA-3h7kA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B2W_A_AG2A401_1
(PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		5 / 10 ASP A 139
ASP A  94
TRP A 125
THR A 221
HIS A 224
 None
AGT  A 366 ( 3.0A)
AGT  A 366 (-3.9A)
AGT  A 366 ( 4.5A)
AGT  A 366 ( 4.1A)
 1.43A 6b2wA-3h7kA:
44.9		 6b2wA-3h7kA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EUQ_A_DXCA502_0
(MULTIDRUG
TRANSPORTER MDFA)		 3h7k AGMATINE DEIMINASE
(Arabidopsis
thaliana) 		5 / 11 ASN A 187
MET A 159
LEU A 161
GLY A 214
LEU A 199
 None
 1.31A 6euqA-3h7kA:
0.0		 6euqA-3h7kA:
21.90