SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h7m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_2
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION
CHIMERA OF IG
GAMMA-1 CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)
3h7m SENSOR PROTEIN
(Geobacter
sulfurreducens)
4 / 5 TYR A  69
TYR A  66
PRO A  67
ASP A  63
None
1.46A 1i7zB-3h7mA:
undetectable
1i7zB-3h7mA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UZ2_A_ACTA1123_0
(XENAVIDIN)
3h7m SENSOR PROTEIN
(Geobacter
sulfurreducens)
4 / 7 ASN A  82
TYR A 238
THR A 139
VAL A 276
None
1.16A 2uz2A-3h7mA:
undetectable
2uz2A-3h7mA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_2
(TRANSPORTER)
3h7m SENSOR PROTEIN
(Geobacter
sulfurreducens)
3 / 3 SER A 232
MET A 211
ASP A 159
None
0.92A 4mm4B-3h7mA:
undetectable
4mm4B-3h7mA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)
3h7m SENSOR PROTEIN
(Geobacter
sulfurreducens)
3 / 3 GLU A 175
TYR A 176
ARG A 180
None
0.86A 5uunA-3h7mA:
undetectable
5uunA-3h7mA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)
3h7m SENSOR PROTEIN
(Geobacter
sulfurreducens)
3 / 3 GLU A 175
TYR A 176
ARG A 180
None
0.81A 5uunB-3h7mA:
undetectable
5uunB-3h7mA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3h7m SENSOR PROTEIN
(Geobacter
sulfurreducens)
3 / 3 ARG A 261
LEU A 257
PHE A 253
None
0.79A 6nknP-3h7mA:
undetectable
6nknP-3h7mA:
22.26