SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h7n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_D_FUAD705_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		5 / 12 THR A 249
PHE A 173
PHE A 199
SER A 250
VAL A 236
 None
 1.47A 1q23D-3h7nA:
undetectable
1q23E-3h7nA:
undetectable		 1q23D-3h7nA:
13.81
1q23E-3h7nA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_F_FUAF704_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		5 / 11 THR A 249
PHE A 173
PHE A 199
SER A 250
VAL A 236
 None
 1.39A 1q23F-3h7nA:
undetectable		 1q23F-3h7nA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		5 / 11 THR A 249
PHE A 173
PHE A 199
SER A 250
VAL A 236
 None
 1.41A 1q23G-3h7nA:
undetectable		 1q23G-3h7nA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		5 / 11 THR A 249
PHE A 173
PHE A 199
SER A 250
VAL A 236
 None
 1.43A 1q23I-3h7nA:
undetectable		 1q23I-3h7nA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  95
PHE A  81
THR A 109
LEU A 108
 None
 0.86A 1v55N-3h7nA:
2.6
1v55W-3h7nA:
undetectable		 1v55N-3h7nA:
21.45
1v55W-3h7nA:
7.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_1
(RETINOIC ACID
RECEPTOR, BETA)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 574
ILE A 579
PHE A 637
LEU A 642
LEU A 570
 None
 0.98A 1xdkB-3h7nA:
undetectable		 1xdkB-3h7nA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_1
(RETINOIC ACID
RECEPTOR, BETA)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 574
ILE A 579
PHE A 637
LEU A 642
LEU A 570
 None
 0.98A 1xdkF-3h7nA:
undetectable		 1xdkF-3h7nA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		5 / 12 TYR A 313
PHE A 315
PHE A 373
THR A 289
LEU A 291
 None
 1.29A 2bjfA-3h7nA:
undetectable		 2bjfA-3h7nA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  95
PHE A  81
THR A 109
LEU A 108
 None
 0.84A 2einA-3h7nA:
2.5
2einJ-3h7nA:
undetectable		 2einA-3h7nA:
21.45
2einJ-3h7nA:
7.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 131
LEU A 117
ILE A 110
LEU A  79
ILE A  95
 None
 1.22A 2f78A-3h7nA:
undetectable		 2f78A-3h7nA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 131
LEU A 117
ILE A 110
LEU A  79
ILE A  95
 None
 1.24A 2f7aA-3h7nA:
undetectable		 2f7aA-3h7nA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 117
VAL A 119
ILE A 110
ILE A  68
 None
 0.90A 2piwA-3h7nA:
undetectable		 2piwA-3h7nA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 526
ASP A 396
GLU A 447
TYR A 415
 None
 1.37A 2ya7C-3h7nA:
2.4		 2ya7C-3h7nA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 571
PHE A 640
LEU A 639
PHE A 562
 None
 1.26A 3abmC-3h7nA:
3.3
3abmJ-3h7nA:
undetectable		 3abmC-3h7nA:
16.12
3abmJ-3h7nA:
7.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  95
PHE A  81
THR A 109
LEU A 108
 None
 0.89A 3asoN-3h7nA:
2.7
3asoW-3h7nA:
undetectable		 3asoN-3h7nA:
21.45
3asoW-3h7nA:
7.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 5 PRO A  18
PRO A  20
TYR A  88
TYR A  15
 None
 1.16A 3d9lA-3h7nA:
3.5
3d9lY-3h7nA:
undetectable		 3d9lA-3h7nA:
10.29
3d9lY-3h7nA:
4.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		5 / 12 THR A 519
GLU A 563
LEU A 570
ILE A 569
LEU A 525
 None
 1.45A 3gwxB-3h7nA:
undetectable		 3gwxB-3h7nA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 205
TYR A 204
GLY A 181
LEU A 183
TRP A 246
 None
 1.29A 3ou6C-3h7nA:
undetectable		 3ou6C-3h7nA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 205
TYR A 204
GLY A 181
LEU A 183
TRP A 246
 None
 1.28A 3ou6D-3h7nA:
undetectable		 3ou6D-3h7nA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 205
TYR A 204
GLY A 181
LEU A 183
TRP A 246
 None
 1.29A 3ou7C-3h7nA:
undetectable		 3ou7C-3h7nA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYE_B_YTZB902_1
(DIHYDROPTEROATE
SYNTHASE)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		3 / 3 PHE A 476
LYS A 356
SER A 361
 None
 1.00A 3tyeB-3h7nA:
undetectable		 3tyeB-3h7nA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		3 / 3 GLN A 424
PHE A 408
TYR A 442
 None
 0.96A 3ucjB-3h7nA:
undetectable		 3ucjB-3h7nA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		3 / 3 GLN A 424
PHE A 408
TYR A 442
 None
 0.95A 3ucjA-3h7nA:
undetectable		 3ucjA-3h7nA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_1
(WBDD)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 6 TYR A 668
ASP A 396
GLN A 390
GLU A 447
 None
 1.49A 4azvA-3h7nA:
undetectable		 4azvA-3h7nA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 8 TYR A  56
ASN A  58
ILE A 463
SER A 461
 None
 0.98A 4eyzA-3h7nA:
undetectable		 4eyzA-3h7nA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 8 TYR A  56
ASN A  58
VAL A 473
SER A 461
 None
 1.02A 4eyzA-3h7nA:
undetectable		 4eyzA-3h7nA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 8 TYR A  56
ASN A  58
ILE A 463
SER A 461
 None
 0.99A 4eyzB-3h7nA:
undetectable		 4eyzB-3h7nA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 8 TYR A  56
ASN A  58
VAL A 473
SER A 461
 None
 1.02A 4eyzB-3h7nA:
undetectable		 4eyzB-3h7nA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 8 ASP A   8
ASN A 383
ASP A 388
GLU A 392
 None
 1.12A 4feuD-3h7nA:
undetectable		 4feuD-3h7nA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 8 ASP A   8
ASN A 383
ASP A 388
GLU A 392
 None
 1.10A 4feuF-3h7nA:
undetectable		 4feuF-3h7nA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 7 ASP A   8
ASN A 383
ASP A 388
GLU A 392
 None
 1.06A 4fevB-3h7nA:
undetectable		 4fevB-3h7nA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 7 ASP A   8
ASN A 383
ASP A 388
GLU A 392
 None
 1.09A 4fevD-3h7nA:
undetectable		 4fevD-3h7nA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 7 ASP A   8
ASN A 383
ASP A 388
GLU A 392
 None
 1.10A 4fevF-3h7nA:
undetectable		 4fevF-3h7nA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 7 ASP A   8
ASN A 383
ASP A 388
GLU A 392
 None
 1.05A 4fewB-3h7nA:
undetectable		 4fewB-3h7nA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 7 ASP A   8
ASN A 383
ASP A 388
GLU A 392
 None
 1.04A 4fexB-3h7nA:
undetectable		 4fexB-3h7nA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		6 / 12 TYR A 701
PHE A 692
LEU A 679
VAL A 678
LEU A 616
TYR A  14
 None
 1.48A 4g1bD-3h7nA:
undetectable		 4g1bD-3h7nA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 8 ASP A   8
ASN A 383
ASP A 388
GLU A 392
 None
 1.08A 4gkhB-3h7nA:
undetectable		 4gkhB-3h7nA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 8 ASP A   8
ASN A 383
ASP A 388
GLU A 392
 None
 1.09A 4gkhD-3h7nA:
undetectable		 4gkhD-3h7nA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 8 ASP A   8
ASN A 383
ASP A 388
GLU A 392
 None
 1.08A 4gkhF-3h7nA:
undetectable		 4gkhF-3h7nA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 7 ASP A   8
ASN A 383
ASP A 388
GLU A 392
 None
 1.10A 4gkhG-3h7nA:
undetectable		 4gkhG-3h7nA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 6 ASP A   8
ASN A 383
ASP A 388
GLU A 392
 None
 1.09A 4gkhJ-3h7nA:
undetectable		 4gkhJ-3h7nA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 8 ASP A   8
ASN A 383
ASP A 388
GLU A 392
 None
 1.11A 4gkhC-3h7nA:
2.4
4gkhK-3h7nA:
undetectable		 4gkhC-3h7nA:
16.00
4gkhK-3h7nA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		5 / 12 ASN A  94
GLN A 477
ASN A 480
ASN A  10
LEU A  12
 None
 1.41A 4kuoA-3h7nA:
undetectable		 4kuoA-3h7nA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 5 VAL A 175
LEU A 234
VAL A 236
PHE A 177
 None
 1.01A 4lb0B-3h7nA:
undetectable		 4lb0B-3h7nA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		5 / 12 GLN A 299
LEU A 243
MET A 259
VAL A 260
VAL A 223
 None
 1.28A 4okxA-3h7nA:
undetectable		 4okxA-3h7nA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_G_IPHG101_0
(INSULIN)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 680
VAL A 709
LEU A 616
LEU A 675
ALA A 676
 None
 1.07A 4p65B-3h7nA:
undetectable
4p65D-3h7nA:
undetectable
4p65G-3h7nA:
undetectable
4p65H-3h7nA:
undetectable		 4p65B-3h7nA:
4.71
4p65D-3h7nA:
4.71
4p65G-3h7nA:
2.59
4p65H-3h7nA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		3 / 3 ILE A 397
ASP A 394
ARG A 628
 None
 0.79A 4pstA-3h7nA:
undetectable		 4pstA-3h7nA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U14_A_0HKA2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 4 ASN A 120
LEU A  60
PHE A  72
TYR A  56
 None
 1.46A 4u14A-3h7nA:
2.7		 4u14A-3h7nA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 7 ILE A  95
PHE A  81
THR A 109
LEU A 108
 None
 0.91A 5b1bN-3h7nA:
4.6
5b1bW-3h7nA:
undetectable		 5b1bN-3h7nA:
21.45
5b1bW-3h7nA:
7.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 7 ILE A  95
PHE A  81
THR A 109
LEU A 108
 None
 0.91A 5b3sN-3h7nA:
2.5
5b3sW-3h7nA:
undetectable		 5b3sN-3h7nA:
21.45
5b3sW-3h7nA:
7.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 7 ILE A  95
PHE A  81
THR A 109
LEU A 108
 None
 0.92A 5iy5N-3h7nA:
3.8
5iy5W-3h7nA:
undetectable		 5iy5N-3h7nA:
21.45
5iy5W-3h7nA:
6.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 571
PHE A 640
LEU A 639
PHE A 562
 None
 1.34A 5xdqP-3h7nA:
2.6
5xdqW-3h7nA:
undetectable		 5xdqP-3h7nA:
16.12
5xdqW-3h7nA:
7.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  95
PHE A  81
THR A 109
LEU A 108
 None
 0.92A 5zcpN-3h7nA:
3.8
5zcpW-3h7nA:
undetectable		 5zcpN-3h7nA:
21.45
5zcpW-3h7nA:
7.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		4 / 7 THR A  77
LEU A  78
ILE A  95
THR A  80
 None
 1.03A 5zsfA-3h7nA:
undetectable
5zsfB-3h7nA:
undetectable		 5zsfA-3h7nA:
7.63
5zsfB-3h7nA:
7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3h7n NUCLEOPORIN NUP120
(Saccharomyces
cerevisiae) 		3 / 3 GLN A 104
TYR A 106
ASN A 103
 None
 1.02A 6dwdC-3h7nA:
undetectable		 6dwdC-3h7nA:
21.35